FN1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description fibronectin 1|This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2335)
External Link https://ncbi.nlm.nih.gov/gene/2335
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Genes

500 genes differentially expressed following the FN1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen 0.0253782
AKAP12 A kinase (PRKA) anchor protein 12 0.0139402
CXCL5 chemokine (C-X-C motif) ligand 5 0.0135757
S100P S100 calcium binding protein P 0.0119304
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0110772
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0101281
GPX2 glutathione peroxidase 2 0.00934442
TSPAN8 tetraspanin 8 0.00933397
TFF3 trefoil factor 3 (intestinal) 0.00923036
LGALS4 lectin, galactoside-binding, soluble, 4 0.00921916
MGP matrix Gla protein 0.00897722
C2CD5 C2 calcium-dependent domain containing 5 0.00891703
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00870787
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.008636
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 0.00859446
AREG amphiregulin 0.00839625
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00800148
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00796862
SRPX sushi-repeat containing protein, X-linked 0.00790865
FAR2 fatty acyl CoA reductase 2 0.0077116
TFF1 trefoil factor 1 0.0077051
BMP6 bone morphogenetic protein 6 0.00759159
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00754573
EREG epiregulin 0.00752284
GMDS GDP-mannose 4,6-dehydratase 0.00751559
DIPK1A divergent protein kinase domain 1A 0.00750298
RXYLT1 ribitol xylosyltransferase 1 0.00739816
SRGN serglycin 0.00728878
ZBTB20 zinc finger and BTB domain containing 20 0.00722662
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00718845
ADIRF adipogenesis regulatory factor 0.007051
KLK6 kallikrein-related peptidase 6 0.00700744
CALB1 calbindin 1, 28kDa 0.00700075
PNMA2 paraneoplastic Ma antigen 2 0.00689348
TESC tescalcin 0.00679407
MYRF myelin regulatory factor 0.00677339
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00676354
BAMBI BMP and activin membrane-bound inhibitor 0.0066926
HEPH hephaestin 0.00663915
MMP1 matrix metallopeptidase 1 0.00657466
NANOG Nanog homeobox 0.00655956
WWTR1 WW domain containing transcription regulator 1 0.00655634
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.00641142
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.00638021
CA12 carbonic anhydrase XII 0.00637587
GPR137B G protein-coupled receptor 137B 0.00636164
TM4SF4 transmembrane 4 L six family member 4 0.00629314
TRIB3 tribbles pseudokinase 3 0.00628639
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00627654
ICAM2 intercellular adhesion molecule 2 0.00625732
NOP56 NOP56 ribonucleoprotein 0.00619142
DUSP6 dual specificity phosphatase 6 0.00614404
PDE4B phosphodiesterase 4B, cAMP-specific 0.00609313
IL17RB interleukin 17 receptor B 0.00604102
DPEP1 dipeptidase 1 (renal) 0.00602014
KIF16B kinesin family member 16B 0.00598419
CRYBG3 beta-gamma crystallin domain containing 3 0.00597126
TOX3 TOX high mobility group box family member 3 0.00595517
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00593238
CALML5 calmodulin-like 5 0.00592465
ANK2 ankyrin 2, neuronal 0.00592259
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00590865
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00590254
CYBA cytochrome b-245, alpha polypeptide 0.00587902
TMX4 thioredoxin-related transmembrane protein 4 0.00586977
ANXA13 annexin A13 0.00584456
ZBTB38 zinc finger and BTB domain containing 38 0.00584295
TM9SF3 transmembrane 9 superfamily member 3 0.00584262
SOX9 SRY (sex determining region Y)-box 9 0.0057942
RNPS1 RNA binding protein S1, serine-rich domain 0.00577664
SALL1 spalt-like transcription factor 1 0.0057652
PWP1 PWP1 homolog (S. cerevisiae) 0.00572793
AMIGO2 adhesion molecule with Ig-like domain 2 0.00565616
HAL histidine ammonia-lyase 0.00565057
FERMT1 fermitin family member 1 0.00564389
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.00564053
COMMD4 COMM domain containing 4 0.00563914
EPS8L3 EPS8-like 3 0.00562841
TCEAL2 transcription elongation factor A (SII)-like 2 0.00559456
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.0055734
NRCAM neuronal cell adhesion molecule 0.0055618
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 0.00553058
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 0.005525
SCAND1 SCAN domain containing 1 0.00551871
MKKS McKusick-Kaufman syndrome 0.00551694
TFF2 trefoil factor 2 0.0054878
PLK1 polo-like kinase 1 0.00548017
PLAAT3 phospholipase A and acyltransferase 3 0.0054776
PROCR protein C receptor, endothelial 0.00547755
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.00547053
DACH1 dachshund family transcription factor 1 0.00541449
EDF1 endothelial differentiation-related factor 1 0.00537297
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00536586
MX1 MX dynamin-like GTPase 1 0.00535799
NEBL nebulette 0.00534157
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.00532759
SACS sacsin molecular chaperone 0.00532562
QPCT glutaminyl-peptide cyclotransferase 0.00528783
ACOT9 acyl-CoA thioesterase 9 0.00526817
KRT23 keratin 23, type I 0.00521841
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00520493
ASCL1 achaete-scute family bHLH transcription factor 1 0.0052044
IER2 immediate early response 2 0.00515718
MT1H metallothionein 1H 0.0051425
MUC13 mucin 13, cell surface associated 0.00513943
GPR183 G protein-coupled receptor 183 0.00513834
BCL2A1 BCL2-related protein A1 0.00513549
CIAPIN1 cytokine induced apoptosis inhibitor 1 0.00512034
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00509929
RGS2 regulator of G-protein signaling 2 0.00506885
F3 coagulation factor III (thromboplastin, tissue factor) 0.00504471
AHI1 Abelson helper integration site 1 0.00500032
ENOPH1 enolase-phosphatase 1 0.00498003
MAB21L2 mab-21-like 2 (C. elegans) 0.00497345
COL9A3 collagen, type IX, alpha 3 0.00493244
RELN reelin 0.00492467
QKI QKI, KH domain containing, RNA binding 0.00492341
PHYH phytanoyl-CoA 2-hydroxylase 0.00488121
CXCL3 chemokine (C-X-C motif) ligand 3 0.0048704
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00486871
NR1D2 nuclear receptor subfamily 1, group D, member 2 0.00486803
RNH1 ribonuclease/angiogenin inhibitor 1 0.00484741
TIMP4 TIMP metallopeptidase inhibitor 4 0.00481553
FA2H fatty acid 2-hydroxylase 0.00479078
TOP2B topoisomerase (DNA) II beta 180kDa 0.0047744
HOXA10 homeobox A10 0.00477187
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00475295
HOMER3 homer scaffolding protein 3 0.00474494
GOLGA8A golgin A8 family, member A 0.00473183
TBC1D4 TBC1 domain family, member 4 0.00473071
C3ORF14 chromosome 3 open reading frame 14 0.00471989
LAMP5 lysosomal-associated membrane protein family, member 5 0.00470765
IFNG interferon, gamma 0.00470695
SDC4 syndecan 4 0.00470354
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00469693
GIPC2 GIPC PDZ domain containing family, member 2 0.00469642
NCALD neurocalcin delta 0.00468682
GSAP gamma-secretase activating protein 0.00467452
FXYD2 FXYD domain containing ion transport regulator 2 0.00463919
GAS2 growth arrest-specific 2 0.00463546
AK1 adenylate kinase 1 0.00462262
TBC1D15 TBC1 domain family, member 15 0.00461935
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.00460076
DGLUCY D-glutamate cyclase 0.00459257
SPRY2 sprouty homolog 2 (Drosophila) 0.00458289
JUNB jun B proto-oncogene 0.00458003
TM4SF20 transmembrane 4 L six family member 20 0.0045736
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 0.00456022
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00454628
ATG3 autophagy related 3 0.00454458
PAH phenylalanine hydroxylase 0.00454346
FCGBP Fc fragment of IgG binding protein 0.0045357
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00452754
OPHN1 oligophrenin 1 0.00452398
KLC1 kinesin light chain 1 0.00451989
PLN phospholamban 0.00451642
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00450288
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00448714
ETFA electron-transfer-flavoprotein, alpha polypeptide 0.00446379
PCBP4 poly(rC) binding protein 4 0.00446341
CIB2 calcium and integrin binding family member 2 0.00445774
IFI35 interferon-induced protein 35 0.00443711
RAB21 RAB21, member RAS oncogene family 0.00443058
E2F2 E2F transcription factor 2 0.00443053
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.00441617
CA9 carbonic anhydrase IX 0.00441164
DERA deoxyribose-phosphate aldolase (putative) 0.00441141
SETBP1 SET binding protein 1 0.00440897
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00440794
ARPC5L actin related protein 2/3 complex, subunit 5-like 0.00440385
GADD45B growth arrest and DNA-damage-inducible, beta 0.00439406
MED27 mediator complex subunit 27 0.00438774
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.00438697
CXCL12 chemokine (C-X-C motif) ligand 12 0.00438468
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.0043823
ANXA5 annexin A5 0.00437177
IER3 immediate early response 3 0.00436826
CARD10 caspase recruitment domain family, member 10 0.00436644
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00435154
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 0.00433252
ELOVL2 ELOVL fatty acid elongase 2 0.00432372
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.00431874
LGALS1 lectin, galactoside-binding, soluble, 1 0.00430997
DUSP22 dual specificity phosphatase 22 0.00430877
FGGY FGGY carbohydrate kinase domain containing 0.00430863
RAB8B RAB8B, member RAS oncogene family 0.00429824
GPM6A glycoprotein M6A 0.00429267
CXCR4 chemokine (C-X-C motif) receptor 4 0.00428324
TNIK TRAF2 and NCK interacting kinase 0.00427522
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00427179
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 0.00427127
BMP2 bone morphogenetic protein 2 0.00427111
ZFAND6 zinc finger, AN1-type domain 6 0.00427103
TSPO translocator protein (18kDa) 0.00426786
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.00425395
RIOX2 ribosomal oxygenase 2 0.00424888
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.0042379
IFI27 interferon, alpha-inducible protein 27 0.00422598
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.00422148
DMD dystrophin 0.00421948
LACTB2 lactamase, beta 2 0.00421574
ETV5 ets variant 5 0.00421562
ARHGAP12 Rho GTPase activating protein 12 0.00420658
MCM7 minichromosome maintenance complex component 7 0.00418631
SINHCAF SIN3-HDAC complex associated factor 0.00418076
RNASET2 ribonuclease T2 0.00417338
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.0041699
C9ORF3 chromosome 9 open reading frame 3 0.00416731
REG1A regenerating islet-derived 1 alpha 0.00416535
NUP214 nucleoporin 214kDa 0.00416393
GATA6 GATA binding protein 6 0.00416205
MCM2 minichromosome maintenance complex component 2 0.00415879
COLEC11 collectin sub-family member 11 0.00415421
GADD45G growth arrest and DNA-damage-inducible, gamma 0.00415178
MTMR11 myotubularin related protein 11 0.00415061
MAP2K5 mitogen-activated protein kinase kinase 5 0.00414624
CRIP1 cysteine-rich protein 1 (intestinal) 0.00412872
PDLIM1 PDZ and LIM domain 1 0.0041218
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.00411184
INSM1 insulinoma-associated 1 0.00410918
DPYSL2 dihydropyrimidinase-like 2 0.00409712
C1QTNF3 C1q and tumor necrosis factor related protein 3 0.00409356
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.00408641
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00408626
JAM3 junctional adhesion molecule 3 0.00408597
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00408362
USP6NL USP6 N-terminal like 0.00407918
GMPS guanine monphosphate synthase 0.00407379
ANAPC5 anaphase promoting complex subunit 5 0.00407288
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.00406655
ETV4 ets variant 4 0.00406539
BBX bobby sox homolog (Drosophila) 0.00406519
ZC4H2 zinc finger, C4H2 domain containing 0.0040504
MT1HL1 metallothionein 1H-like 1 0.00405038
VNN1 vanin 1 0.00403763
PPCDC phosphopantothenoylcysteine decarboxylase 0.00402502
CTSC cathepsin C 0.00401932
FANCL Fanconi anemia, complementation group L 0.00401673
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 0.00401428
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00401211
HIP1R huntingtin interacting protein 1 related 0.00400513
PYGB phosphorylase, glycogen; brain 0.00399827
IST1 increased sodium tolerance 1 homolog (yeast) 0.00398959
H1-10 H1.10 linker histone 0.00397985
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.00397753
SEC23B Sec23 homolog B (S. cerevisiae) 0.00397289
CAPRIN2 caprin family member 2 0.00397089
NCAM1 neural cell adhesion molecule 1 0.00397049
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 0.00396746
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.00396153

decreased expression

Symbol Name Standardized Value
GNAS GNAS complex locus -0.0208277
AQP3 aquaporin 3 (Gill blood group) -0.013453
KRT5 keratin 5, type II -0.0133986
KRT17 keratin 17, type I -0.0125402
TACSTD2 tumor-associated calcium signal transducer 2 -0.0122818
S100A2 S100 calcium binding protein A2 -0.0111357
KRT19 keratin 19, type I -0.010766
C3 complement component 3 -0.0105068
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.0102473
CD52 CD52 molecule -0.0100978
GLUL glutamate-ammonia ligase -0.0100059
SC5D sterol-C5-desaturase -0.00950698
SLPI secretory leukocyte peptidase inhibitor -0.0092432
XIC X chromosome inactivation center -0.00899935
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00872154
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00857855
PRSS8 protease, serine, 8 -0.00849524
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00839119
COL4A5 collagen, type IV, alpha 5 -0.00838999
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00835912
FN1 fibronectin 1 -0.00835551
CP ceruloplasmin (ferroxidase) -0.0082135
CFB complement factor B -0.00820671
CHKB choline kinase beta -0.00816726
GJA1 gap junction protein, alpha 1, 43kDa -0.00813944
KIAA0100 KIAA0100 -0.00792749
TCTA T-cell leukemia translocation altered -0.00784652
FOLR1 folate receptor 1 (adult) -0.00782875
MMP7 matrix metallopeptidase 7 -0.00773939
CD9 CD9 molecule -0.00772867
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00767564
SELENBP1 selenium binding protein 1 -0.00760618
IL7R interleukin 7 receptor -0.00753921
RGCC regulator of cell cycle -0.00753322
CCL19 chemokine (C-C motif) ligand 19 -0.00753094
SNAI2 snail family zinc finger 2 -0.00752922
MPZL2 myelin protein zero-like 2 -0.00747413
A2M alpha-2-macroglobulin -0.00744657
KRT15 keratin 15, type I -0.00743096
CPA3 carboxypeptidase A3 (mast cell) -0.00741433
KRT13 keratin 13, type I -0.00737266
DHCR24 24-dehydrocholesterol reductase -0.00736114
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00735561
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.0073148
CRABP2 cellular retinoic acid binding protein 2 -0.00725361
ABHD3 abhydrolase domain containing 3 -0.0072169
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.00719267
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00717864
PEA15 phosphoprotein enriched in astrocytes 15 -0.00711656
MMP9 matrix metallopeptidase 9 -0.00710686
ITGA6 integrin, alpha 6 -0.00710657
GAL galanin/GMAP prepropeptide -0.00701605
KRT6A keratin 6A, type II -0.00699221
CLCA4 chloride channel accessory 4 -0.00693551
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00692987
LAMB3 laminin, beta 3 -0.00685895
SORD sorbitol dehydrogenase -0.00684959
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00684045
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.0068388
TSC22D1 TSC22 domain family, member 1 -0.00683612
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -0.00681657
EGFL6 EGF-like-domain, multiple 6 -0.00680107
GDE1 glycerophosphodiester phosphodiesterase 1 -0.00676766
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.00674635
EXPH5 exophilin 5 -0.00673011
CNN3 calponin 3, acidic -0.00671704
FOXF2 forkhead box F2 -0.0066925
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00666197
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00665523
WBP5 WW domain binding protein 5 -0.00664978
ADARB1 adenosine deaminase, RNA-specific, B1 -0.00664404
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00663768
NKX3-1 NK3 homeobox 1 -0.00659659
CLCA2 chloride channel accessory 2 -0.00653801
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -0.00653759
PLAT plasminogen activator, tissue -0.00650065
CXADR coxsackie virus and adenovirus receptor -0.00646036
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.00640051
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00636533
COL15A1 collagen, type XV, alpha 1 -0.00633361
ASS1 argininosuccinate synthase 1 -0.00632397
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -0.00629769
EIF5A eukaryotic translation initiation factor 5A -0.00629324
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00624994
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.00623522
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00622867
TGM2 transglutaminase 2 -0.00620303
NELL2 NEL-like 2 (chicken) -0.00618796
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00615359
EMP1 epithelial membrane protein 1 -0.00614196
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00614035
CLEC2B C-type lectin domain family 2, member B -0.00610444
RAD23B RAD23 homolog B (S. cerevisiae) -0.00609961
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00607441
NDFIP1 Nedd4 family interacting protein 1 -0.00606966
BEX4 brain expressed, X-linked 4 -0.00606109
PITX1 paired-like homeodomain 1 -0.00605941
MEST mesoderm specific transcript -0.0060471
MYO1B myosin IB -0.00602902
NMU neuromedin U -0.00598154
MALL mal, T-cell differentiation protein-like -0.00597333
HIRA histone cell cycle regulator -0.00596045
LOX lysyl oxidase -0.00594727
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.00594432
PPL periplakin -0.00594186
GGCX gamma-glutamyl carboxylase -0.0059199
ELOVL5 ELOVL fatty acid elongase 5 -0.00589508
BIRC2 baculoviral IAP repeat containing 2 -0.00583934
FASN fatty acid synthase -0.00582801
ADM adrenomedullin -0.00580354
YAP1 Yes-associated protein 1 -0.00580294
MMP11 matrix metallopeptidase 11 -0.00578533
MMP13 matrix metallopeptidase 13 -0.00578001
RIPOR2 RHO family interacting cell polarization regulator 2 -0.00576946
C1RL complement component 1, r subcomponent-like -0.00574771
BCL6 B-cell CLL/lymphoma 6 -0.00574764
DSP desmoplakin -0.00573681
ESRP1 epithelial splicing regulatory protein 1 -0.00569794
SIRT3 sirtuin 3 -0.00569354
SFTPC surfactant protein C -0.00568551
PRDX6 peroxiredoxin 6 -0.00567383
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00566567
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -0.00563443
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 -0.00561213
OLFM1 olfactomedin 1 -0.00560892
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.00559419
MAPK1 mitogen-activated protein kinase 1 -0.00559289
COL11A1 collagen, type XI, alpha 1 -0.00559242
WFDC2 WAP four-disulfide core domain 2 -0.00558951
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00557892
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.00557355
FOXA1 forkhead box A1 -0.00556843
CD99 CD99 molecule -0.00555707
NXN nucleoredoxin -0.00555487
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.00555321
FGFR2 fibroblast growth factor receptor 2 -0.00550813
DDR2 discoidin domain receptor tyrosine kinase 2 -0.00550594
FGFR3 fibroblast growth factor receptor 3 -0.00548995
LCN2 lipocalin 2 -0.00546393
SEPP1 selenoprotein P, plasma, 1 -0.00546026
FGG fibrinogen gamma chain -0.00543253
SFTPB surfactant protein B -0.00542334
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00540222
EPCAM epithelial cell adhesion molecule -0.00539636
IFITM1 interferon induced transmembrane protein 1 -0.00536953
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00536808
ATAD2 ATPase family, AAA domain containing 2 -0.00535512
CLDN7 claudin 7 -0.00534372
NIBAN1 niban apoptosis regulator 1 -0.00534113
LEF1 lymphoid enhancer-binding factor 1 -0.00533039
HIST1H2BD histone cluster 1, H2bd -0.00528442
S100A4 S100 calcium binding protein A4 -0.00527525
IGFBP5 insulin-like growth factor binding protein 5 -0.0052684
AHCYL1 adenosylhomocysteinase-like 1 -0.0052643
FABP4 fatty acid binding protein 4, adipocyte -0.00524637
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -0.00524118
C4BPA complement component 4 binding protein, alpha -0.0052374
CLU clusterin -0.00522349
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -0.0052232
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 -0.00517822
TRIM29 tripartite motif containing 29 -0.00516953
DPYD dihydropyrimidine dehydrogenase -0.0051434
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -0.00513907
MXI1 MAX interactor 1, dimerization protein -0.00511331
PGD phosphogluconate dehydrogenase -0.00511121
SCARB2 scavenger receptor class B, member 2 -0.00508665
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.00508662
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit -0.00508242
GCG glucagon -0.00508039
ACP2 acid phosphatase 2, lysosomal -0.00507803
ALG8 ALG8, alpha-1,3-glucosyltransferase -0.00507433
TSPAN6 tetraspanin 6 -0.00504167
SOD2 superoxide dismutase 2, mitochondrial -0.00503424
NPTXR neuronal pentraxin receptor -0.00501071
SPINT1 serine peptidase inhibitor, Kunitz type 1 -0.00500073
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.00499608
RGS4 regulator of G-protein signaling 4 -0.004993
NCK1 NCK adaptor protein 1 -0.00499101
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -0.00496437
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.00496411
EHF ets homologous factor -0.00495599
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.00494102
GSTM3 glutathione S-transferase mu 3 (brain) -0.00492962
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00492705
GANAB glucosidase, alpha; neutral AB -0.00492673
F13A1 coagulation factor XIII, A1 polypeptide -0.00491791
SPTAN1 spectrin, alpha, non-erythrocytic 1 -0.00491333
FKBP4 FK506 binding protein 4, 59kDa -0.00489952
GSTA1 glutathione S-transferase alpha 1 -0.00489669
FBN2 fibrillin 2 -0.00487204
TRIB2 tribbles pseudokinase 2 -0.00486721
UXS1 UDP-glucuronate decarboxylase 1 -0.00485469
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.00485398
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.00484933
LRP5 low density lipoprotein receptor-related protein 5 -0.00484176
TWSG1 twisted gastrulation BMP signaling modulator 1 -0.0048242
ANOS1 anosmin 1 -0.00482388
ZNF512B zinc finger protein 512B -0.0048187
CD2 CD2 molecule -0.00481546
PLAU plasminogen activator, urokinase -0.00480453
TAPBP TAP binding protein (tapasin) -0.00479985
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00478916
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00478271
BAG3 BCL2-associated athanogene 3 -0.00477513
CRISP3 cysteine-rich secretory protein 3 -0.00477177
ATXN10 ataxin 10 -0.00476892
JCHAIN joining chain of multimeric IgA and IgM -0.00476352
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -0.00475383
MSMO1 methylsterol monooxygenase 1 -0.00475043
CPM carboxypeptidase M -0.00474268
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00473876
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00473637
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -0.004728
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00472642
COPS7A COP9 signalosome subunit 7A -0.00471962
SFTPD surfactant protein D -0.00471138
IDO1 indoleamine 2,3-dioxygenase 1 -0.00470051
NELFCD negative elongation factor complex member C/D -0.00469435
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) -0.0046907
HAT1 histone acetyltransferase 1 -0.0046901
MECOM MDS1 and EVI1 complex locus -0.00467664
LPIN1 lipin 1 -0.00467322
NPC2 Niemann-Pick disease, type C2 -0.00464618
HDAC9 histone deacetylase 9 -0.00464443
CPE carboxypeptidase E -0.00464014
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00462982
SELL selectin L -0.00462718
BAZ1A bromodomain adjacent to zinc finger domain, 1A -0.00462053
ANKRD17 ankyrin repeat domain 17 -0.00461966
APOA1 apolipoprotein A-I -0.00461345
SPINK5 serine peptidase inhibitor, Kazal type 5 -0.00460267
SOWAHC sosondowah ankyrin repeat domain family member C -0.00457519
STC1 stanniocalcin 1 -0.00457089
CKAP4 cytoskeleton-associated protein 4 -0.00457074
COL5A1 collagen, type V, alpha 1 -0.00456597
RHOBTB3 Rho-related BTB domain containing 3 -0.00456123
VAV3 vav 3 guanine nucleotide exchange factor -0.0045525
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00454627
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00451994
LAMP3 lysosomal-associated membrane protein 3 -0.0045116
CS citrate synthase -0.00451044
ST14 suppression of tumorigenicity 14 (colon carcinoma) -0.00450606
RUNX3 runt-related transcription factor 3 -0.00450527
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00449439
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -0.00449002
TMPRSS2 transmembrane protease, serine 2 -0.00448975
ITGB6 integrin, beta 6 -0.00448408
MCTP2 multiple C2 domains, transmembrane 2 -0.00446837
TMPRSS4 transmembrane protease, serine 4 -0.00446144
COX6C cytochrome c oxidase subunit VIc -0.00444766