FOS Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description FBJ murine osteosarcoma viral oncogene homolog|The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2353)
Similar Terms
Downloads & Tools

Genes

309 genes differentially expressed following the FOS gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ZPLD1 zona pellucida-like domain containing 1 3.23781
TTC16 tetratricopeptide repeat domain 16 3.23781
C6ORF118 chromosome 6 open reading frame 118 3.23781
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4 3.23781
NR1I3 nuclear receptor subfamily 1, group I, member 3 3.23781
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 3.23781
ARL5C ADP-ribosylation factor-like 5C 3.23781
DDTL D-dopachrome tautomerase-like 3.23781
PCDHA2 protocadherin alpha 2 3.23781
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 3.23781
CLEC19A C-type lectin domain family 19, member A 3.23781
NPSR1 neuropeptide S receptor 1 3.23781
FAM221B family with sequence similarity 221, member B 3.23781
CRYGN crystallin, gamma N 3.23781
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6 3.23781
SPON2 spondin 2, extracellular matrix protein 3.23781
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 3.23781
PCDHAC1 protocadherin alpha subfamily C, 1 3.23781
GLIPR1 GLI pathogenesis-related 1 3.23781
C22ORF31 chromosome 22 open reading frame 31 3.23781
IHO1 interactor of HORMAD1 1 3.23781
MEPE matrix extracellular phosphoglycoprotein 3.23781
SQOR sulfide quinone oxidoreductase 3.23781
CPSF4L cleavage and polyadenylation specific factor 4-like 3.23781
CELA3A chymotrypsin-like elastase family, member 3A 3.13935
SIGLEC5 sialic acid binding Ig-like lectin 5 3.13935
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 3.13935
TXNDC8 thioredoxin domain containing 8 (spermatozoa) 3.13935
FABP1 fatty acid binding protein 1, liver 3.13935
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 3.13935
GJB1 gap junction protein, beta 1, 32kDa 3.13935
MAGEA2 melanoma antigen family A2 3.13935
SLC25A45 solute carrier family 25, member 45 3.13935
PRSS41 protease, serine, 41 3.13935
VXN vexin 3.13935
PEAR1 platelet endothelial aggregation receptor 1 3.13935
SSTR5 somatostatin receptor 5 3.13935
TRIM74 tripartite motif containing 74 3.13935
SLC39A5 solute carrier family 39 (zinc transporter), member 5 3.13935
LPA lipoprotein, Lp(a) 3.13935
ICAM2 intercellular adhesion molecule 2 3.13935
MNX1 motor neuron and pancreas homeobox 1 3.13935
CLCF1 cardiotrophin-like cytokine factor 1 3.13935
SPAG6 sperm associated antigen 6 3.13935
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 3.13935
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 3.13935
LOC122526780 uncharacterized LOC122526780 3.13935
GALR3 galanin receptor 3 3.13935
PTK6 protein tyrosine kinase 6 3.13935
SETSIP SET-like protein 3.13935
OR52B2 olfactory receptor, family 52, subfamily B, member 2 3.13935
GUCY2F guanylate cyclase 2F, retinal 3.13935
HAS1 hyaluronan synthase 1 3.13935
DUSP29 dual specificity phosphatase 29 3.13935
XAF1 XIAP associated factor 1 3.13935
CTRC chymotrypsin C (caldecrin) 3.13935
MS4A4E membrane-spanning 4-domains, subfamily A, member 4E 3.13935
SPEM1 spermatid maturation 1 3.13935
SLC45A2 solute carrier family 45, member 2 3.13935
C12ORF54 chromosome 12 open reading frame 54 3.13935
COL3A1 collagen, type III, alpha 1 3.13935
S100P S100 calcium binding protein P 3.13935
IQCF1 IQ motif containing F1 3.13935
S100G S100 calcium binding protein G 3.13935
SAA1 serum amyloid A1 3.13935
OPN5 opsin 5 3.13935
RHOXF2 Rhox homeobox family, member 2 3.13935
PABPC1L2A poly(A) binding protein, cytoplasmic 1-like 2A 3.13935
MOV10L1 Mov10 RISC complex RNA helicase like 1 3.13935
SOAT2 sterol O-acyltransferase 2 3.13935
GATA3 GATA binding protein 3 3.13935
C15ORF62 chromosome 15 open reading frame 62 3.13935
TBX10 T-box 10 3.13935
OR8D4 olfactory receptor, family 8, subfamily D, member 4 3.13935
AKR7L aldo-keto reductase family 7-like (gene/pseudogene) 3.13935
SIX6 SIX homeobox 6 3.13935
SIX1 SIX homeobox 1 3.13935
GJA3 gap junction protein, alpha 3, 46kDa 3.13935
VSIR V-set immunoregulatory receptor 3.13935
OR5H2 olfactory receptor, family 5, subfamily H, member 2 3.13935
RAB44 RAB44, member RAS oncogene family 3.13935
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 3.13935
AVPR1B arginine vasopressin receptor 1B 3.13935
C5ORF52 chromosome 5 open reading frame 52 3.13935
MAGEB1 melanoma antigen family B1 3.13935
VSX2 visual system homeobox 2 3.13935
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 3.13935
AKR1D1 aldo-keto reductase family 1, member D1 3.13935
C3ORF80 chromosome 3 open reading frame 80 3.13935
MYL10 myosin, light chain 10, regulatory 3.13935
ZNF648 zinc finger protein 648 3.13935
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 3.13935
ARR3 arrestin 3, retinal (X-arrestin) 3.13935
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 3.13935
DQX1 DEAQ box RNA-dependent ATPase 1 3.13935
SPATA9 spermatogenesis associated 9 3.13935
EBLN1 endogenous Bornavirus-like nucleoprotein 1 3.13935
C18ORF63 chromosome 18 open reading frame 63 3.13935
SAMD7 sterile alpha motif domain containing 7 3.13935
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 3.13935
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 3.13935
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 3.13935
RFPL1 ret finger protein-like 1 3.13935
APLNR apelin receptor 3.13935
PAGR1 PAXIP1 associated glutamate-rich protein 1 3.13935
NLRP14 NLR family, pyrin domain containing 14 3.13935
KCNK9 potassium channel, two pore domain subfamily K, member 9 3.13935
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 3.13935
ZNF596 zinc finger protein 596 3.13935
MUC13 mucin 13, cell surface associated 3.13935
C2CD4A C2 calcium-dependent domain containing 4A 3.13935
FIBIN fin bud initiation factor homolog (zebrafish) 3.13935
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 3.13935
PSKH2 protein serine kinase H2 3.13935
CDH10 cadherin 10, type 2 (T2-cadherin) 3.13935
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 3.13935
HKDC1 hexokinase domain containing 1 3.13935
CATIP ciliogenesis associated TTC17 interacting protein 3.13935
TRADD TNFRSF1A-associated via death domain 3.13935
CALHM1 calcium homeostasis modulator 1 3.13935
WFDC9 WAP four-disulfide core domain 9 3.13935
GOLGA6D golgin A6 family, member D 3.13935
EMX2 empty spiracles homeobox 2 3.13935
FBXO47 F-box protein 47 3.13935
CCL24 chemokine (C-C motif) ligand 24 3.13935
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 3.13935
TMIGD2 transmembrane and immunoglobulin domain containing 2 3.13935
NUTM2A NUT family member 2A 3.13935
FADS6 fatty acid desaturase 6 3.13935
ADGRF5 adhesion G protein-coupled receptor F5 3.13935
TYR tyrosinase 3.13935
THEM5 thioesterase superfamily member 5 3.13935
CNR2 cannabinoid receptor 2 (macrophage) 3.13935
A1CF APOBEC1 complementation factor 3.13935
TGM6 transglutaminase 6 3.13935
LMX1A LIM homeobox transcription factor 1, alpha 3.13935
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 3.13935
TEX29 testis expressed 29 3.13935
FOXS1 forkhead box S1 3.13935
BANF2 barrier to autointegration factor 2 3.13935
GPR179 G protein-coupled receptor 179 3.13935
GAS2L2 growth arrest-specific 2 like 2 3.13935
PLA2G4E phospholipase A2, group IVE 3.13935
ERMN ermin, ERM-like protein 3.13935
FEZF2 FEZ family zinc finger 2 3.13935
FGR FGR proto-oncogene, Src family tyrosine kinase 3.13935
OR3A1 olfactory receptor, family 3, subfamily A, member 1 3.13935
ATP10B ATPase, class V, type 10B 3.13935
LHX5 LIM homeobox 5 3.13935
CIDEA cell death-inducing DFFA-like effector a 3.13935
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 3.13935
MOS v-mos Moloney murine sarcoma viral oncogene homolog 3.13935
LMAN1L lectin, mannose-binding, 1 like 3.13935
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene) 3.13935
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 3.05231
BEST1 bestrophin 1 3.02622
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.88444
RABL2A RAB, member of RAS oncogene family-like 2A 2.78734
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) 2.77272
JAK1 Janus kinase 1 2.71631
RWDD1 RWD domain containing 1 2.64221
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 2.51711
SHISAL1 shisa like 1 2.49549
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2.43967
ARRB2 arrestin, beta 2 2.42407
RNF185 ring finger protein 185 2.40345
GPANK1 G patch domain and ankyrin repeats 1 2.37533
HCRTR1 hypocretin (orexin) receptor 1 2.36243
STYXL1 serine/threonine/tyrosine interacting-like 1 2.33437
CH25H cholesterol 25-hydroxylase 2.31861
NRROS negative regulator of reactive oxygen species 2.29622
F11 coagulation factor XI 2.28316
ZFP82 ZFP82 zinc finger protein 2.23465
LIN28A lin-28 homolog A (C. elegans) 2.21805
TUBB1 tubulin, beta 1 class VI 2.2112
G2E3 G2/M-phase specific E3 ubiquitin protein ligase 2.20676
TMEM170B transmembrane protein 170B 2.19085
MFSD11 major facilitator superfamily domain containing 11 2.16911
SYPL1 synaptophysin-like 1 2.16346
MEX3B mex-3 RNA binding family member B 2.16346
MTSS2 MTSS I-BAR domain containing 2 2.1464
VEGFB vascular endothelial growth factor B 2.14065
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.1008
TSC2 tuberous sclerosis 2 2.0873
MTFMT mitochondrial methionyl-tRNA formyltransferase 2.07302
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 2.06826
LMF2 lipase maturation factor 2 2.06647
SCHIP1 schwannomin interacting protein 1 2.05894
SVIP small VCP/p97-interacting protein 2.03151
MSANTD4 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils 2.03139
CAMK1G calcium/calmodulin-dependent protein kinase IG 2.03139
MARCHF10 membrane associated ring-CH-type finger 10 2.03139
TMEM233 transmembrane protein 233 2.03139
INO80E INO80 complex subunit E 2.03139
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 2.03139
STARD3 StAR-related lipid transfer (START) domain containing 3 2.03139
PLA2G12A phospholipase A2, group XIIA 2.02285
MED18 mediator complex subunit 18 2.02166
NLGN4X neuroligin 4, X-linked 2.01163
GRB14 growth factor receptor-bound protein 14 2.00175

decreased expression

Symbol Name Standardized Value
SETD7 SET domain containing (lysine methyltransferase) 7 -3.23781
CYTIP cytohesin 1 interacting protein -3.23781
IQCJ IQ motif containing J -3.23781
CAPN11 calpain 11 -3.23781
LAMP3 lysosomal-associated membrane protein 3 -3.13935
MYPN myopalladin -3.13935
GCKR glucokinase (hexokinase 4) regulator -3.13935
MKX mohawk homeobox -3.13935
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -3.13935
ACTA2 actin, alpha 2, smooth muscle, aorta -3.13935
CD80 CD80 molecule -3.13935
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3 -3.13935
USP32 ubiquitin specific peptidase 32 -3.13935
CCNY cyclin Y -3.13935
CXCL2 chemokine (C-X-C motif) ligand 2 -3.13935
LY6H lymphocyte antigen 6 complex, locus H -3.13935
TMEM236 transmembrane protein 236 -3.13935
HAL histidine ammonia-lyase -3.13935
S100B S100 calcium binding protein B -3.13935
CMKLR1 chemerin chemokine-like receptor 1 -3.13935
SIM1 single-minded family bHLH transcription factor 1 -3.13935
NPB neuropeptide B -3.13935
LRRTM2 leucine rich repeat transmembrane neuronal 2 -3.13935
BTC betacellulin -3.13935
TXLNB taxilin beta -3.13935
UPB1 ureidopropionase, beta -3.13935
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 -3.13935
EIF3CL eukaryotic translation initiation factor 3, subunit C-like -3.13935
DUSP15 dual specificity phosphatase 15 -3.13935
TMEM100 transmembrane protein 100 -3.13935
GJB3 gap junction protein, beta 3, 31kDa -3.13935
PARP3 poly (ADP-ribose) polymerase family, member 3 -3.13935
ASPA aspartoacylase -3.13935
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1 -3.13935
HCRTR2 hypocretin (orexin) receptor 2 -3.13935
LOC124902694 uncharacterized LOC124902694 -3.12464
PABPC4L poly(A) binding protein, cytoplasmic 4-like -3.03899
FBXO6 F-box protein 6 -3.02684
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.88309
CSRP1 cysteine and glycine-rich protein 1 -2.78734
ZNF658 zinc finger protein 658 -2.78734
VIM vimentin -2.73412
PTGIS prostaglandin I2 (prostacyclin) synthase -2.72917
SLIT1 slit homolog 1 (Drosophila) -2.71779
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -2.68895
CNST consortin, connexin sorting protein -2.68342
SAMTOR S-adenosylmethionine sensor upstream of mTORC1 -2.64792
SORBS1 sorbin and SH3 domain containing 1 -2.63798
ARMCX6 armadillo repeat containing, X-linked 6 -2.63366
LIN7A lin-7 homolog A (C. elegans) -2.59582
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin -2.51141
LRRC75A leucine rich repeat containing 75A -2.49549
HLA-G major histocompatibility complex, class I, G -2.43967
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) -2.40192
CRLS1 cardiolipin synthase 1 -2.3892
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 -2.37533
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10 -2.36243
SPDYE17 speedy/RINGO cell cycle regulator family member E17 -2.35818
MMP28 matrix metallopeptidase 28 -2.35818
ZNF600 zinc finger protein 600 -2.32209
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -2.32189
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 -2.30909
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) -2.30909
DNAAF11 dynein axonemal assembly factor 11 -2.29567
FGF8 fibroblast growth factor 8 (androgen-induced) -2.28526
FMNL2 formin-like 2 -2.28316
TANGO2 transport and golgi organization 2 homolog (Drosophila) -2.27661
ZNF157 zinc finger protein 157 -2.25209
MED15 mediator complex subunit 15 -2.24634
CALY calcyon neuron-specific vesicular protein -2.24592
PLA2G10 phospholipase A2, group X -2.24592
TGM2 transglutaminase 2 -2.24592
GOLGA6L10 golgin A6 family-like 10 -2.24592
SGK3 serum/glucocorticoid regulated kinase family, member 3 -2.24275
MED13 mediator complex subunit 13 -2.23465
MTNAP1 mitochondrial nucleoid associated protein 1 -2.23465
KRI1 KRI1 homolog (S. cerevisiae) -2.21791
ETFBKMT electron transfer flavoprotein subunit beta lysine methyltransferase -2.19307
FGF20 fibroblast growth factor 20 -2.19307
TRIM54 tripartite motif containing 54 -2.19307
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 -2.19307
CPNE1 copine I -2.19052
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae) -2.18779
EFCAB11 EF-hand calcium binding domain 11 -2.18121
MRPL43 mitochondrial ribosomal protein L43 -2.16346
FERMT2 fermitin family member 2 -2.15576
NMNAT3 nicotinamide nucleotide adenylyltransferase 3 -2.14976
TGFA transforming growth factor, alpha -2.1465
HRC histidine rich calcium binding protein -2.14362
RGS22 regulator of G-protein signaling 22 -2.14362
NLGN2 neuroligin 2 -2.12439
ACTR5 ARP5 actin-related protein 5 homolog (yeast) -2.12259
GRM5 glutamate receptor, metabotropic 5 -2.11797
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 -2.10849
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 -2.10849
EXOC6 exocyst complex component 6 -2.10622
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) -2.09746
RTEL1 regulator of telomere elongation helicase 1 -2.09591
METTL27 methyltransferase like 27 -2.09591
CHMP2B charged multivesicular body protein 2B -2.09371
GLUD1 glutamate dehydrogenase 1 -2.07155
MATN3 matrilin 3 -2.06647
IER2 immediate early response 2 -2.06647
MRPS16 mitochondrial ribosomal protein S16 -2.05623
SERGEF secretion regulating guanine nucleotide exchange factor -2.03139
TRAF2 TNF receptor-associated factor 2 -2.02166
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -2.02166
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific -2.00278
DDIAS DNA damage-induced apoptosis suppressor -2.00259