FOXA1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description forkhead box A1|This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3169)
External Link https://ncbi.nlm.nih.gov/gene/3169
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Genes

498 genes differentially expressed following the FOXA1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 0.0182692
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0161551
AQP3 aquaporin 3 (Gill blood group) 0.0140707
KRT23 keratin 23, type I 0.0132301
S100A7 S100 calcium binding protein A7 0.0130951
SDC1 syndecan 1 0.0126098
CRISP3 cysteine-rich secretory protein 3 0.0123766
CXCL9 chemokine (C-X-C motif) ligand 9 0.0122426
TXNDC9 thioredoxin domain containing 9 0.0113138
MAGEA3 melanoma antigen family A3 0.0111738
KRT5 keratin 5, type II 0.0109828
S100A9 S100 calcium binding protein A9 0.0108366
FZD6 frizzled class receptor 6 0.0107375
ALCAM activated leukocyte cell adhesion molecule 0.0107253
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.0107058
KRT17 keratin 17, type I 0.0105372
PSCA prostate stem cell antigen 0.010371
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.0103683
GNAS GNAS complex locus 0.0102493
ELF5 E74-like factor 5 (ets domain transcription factor) 0.0102214
RAI14 retinoic acid induced 14 0.0101489
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.0100455
CLC Charcot-Leyden crystal galectin 0.00982344
KRT15 keratin 15, type I 0.00977625
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00959847
MDFIC MyoD family inhibitor domain containing 0.00957895
GPNMB glycoprotein (transmembrane) nmb 0.00918781
XPO7 exportin 7 0.00898491
MFAP3L microfibrillar-associated protein 3-like 0.0089491
PLAT plasminogen activator, tissue 0.00887356
S100A2 S100 calcium binding protein A2 0.00880016
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00871368
UPK1B uroplakin 1B 0.00867092
WT1 Wilms tumor 1 0.00863158
PFN2 profilin 2 0.00856522
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00846244
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00842679
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.00836927
MSMB microseminoprotein, beta- 0.00834498
PRKD3 protein kinase D3 0.00822811
AMIGO2 adhesion molecule with Ig-like domain 2 0.00817736
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.00815437
ANKRD46 ankyrin repeat domain 46 0.00813168
GBP1 guanylate binding protein 1, interferon-inducible 0.00809836
KAT2B K(lysine) acetyltransferase 2B 0.00808381
CBR4 carbonyl reductase 4 0.00802709
CLCA2 chloride channel accessory 2 0.00801139
QPCT glutaminyl-peptide cyclotransferase 0.00800848
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00797537
CLDN10 claudin 10 0.00793967
HNMT histamine N-methyltransferase 0.00788015
MARCKSL1 MARCKS-like 1 0.00786362
MINPP1 multiple inositol-polyphosphate phosphatase 1 0.00772579
CXCL11 chemokine (C-X-C motif) ligand 11 0.0077251
KRT14 keratin 14, type I 0.00768836
APOL1 apolipoprotein L, 1 0.00768151
CXCL14 chemokine (C-X-C motif) ligand 14 0.00767301
PERP PERP, TP53 apoptosis effector 0.00766395
LCN2 lipocalin 2 0.0076259
OSBPL3 oxysterol binding protein-like 3 0.00762528
KRCC1 lysine-rich coiled-coil 1 0.00754006
DPYD dihydropyrimidine dehydrogenase 0.00751826
CD59 CD59 molecule, complement regulatory protein 0.00744736
TOX3 TOX high mobility group box family member 3 0.00738533
EVI5 ecotropic viral integration site 5 0.00736429
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.00736221
CCL5 chemokine (C-C motif) ligand 5 0.00735422
DIPK1A divergent protein kinase domain 1A 0.00733837
TMEM45A transmembrane protein 45A 0.00732691
KRT6A keratin 6A, type II 0.00725347
ANXA1 annexin A1 0.0072482
CD38 CD38 molecule 0.00720233
SPRR1B small proline-rich protein 1B 0.00719948
TCTA T-cell leukemia translocation altered 0.00717363
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 0.00713874
DENND1B DENN/MADD domain containing 1B 0.00708395
MUC16 mucin 16, cell surface associated 0.00708215
ASF1A anti-silencing function 1A histone chaperone 0.00706207
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00705707
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00701912
ARID4B AT rich interactive domain 4B (RBP1-like) 0.00701047
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 0.0070052
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.00699073
CXCL10 chemokine (C-X-C motif) ligand 10 0.00697696
LUM lumican 0.00688959
USP6NL USP6 N-terminal like 0.00687235
MPZL2 myelin protein zero-like 2 0.00684802
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 0.00684697
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.0067982
LY75 lymphocyte antigen 75 0.00677987
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.0067654
WIPF1 WAS/WASL interacting protein family, member 1 0.00676485
TYRP1 tyrosinase-related protein 1 0.00675105
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.00674892
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00674705
VCAM1 vascular cell adhesion molecule 1 0.00674228
ATP7B ATPase, Cu++ transporting, beta polypeptide 0.00671034
SRGN serglycin 0.00670923
SPART spartin 0.00667573
INSIG2 insulin induced gene 2 0.00667126
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 0.00666096
PROM1 prominin 1 0.00664988
GCH1 GTP cyclohydrolase 1 0.00663779
AHNAK2 AHNAK nucleoprotein 2 0.00662843
YPEL5 yippee-like 5 (Drosophila) 0.00659956
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.00658536
PIR pirin (iron-binding nuclear protein) 0.00653828
MOSPD1 motile sperm domain containing 1 0.0065024
TMEM106B transmembrane protein 106B 0.0064735
KANK1 KN motif and ankyrin repeat domains 1 0.00647122
COL3A1 collagen, type III, alpha 1 0.0064678
CCPG1 cell cycle progression 1 0.00646518
SLAMF7 SLAM family member 7 0.00646419
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 0.0064254
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 0.00641756
FAM3C family with sequence similarity 3, member C 0.00641225
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.00638601
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.00636239
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00635061
ENOPH1 enolase-phosphatase 1 0.00634279
CCN2 cellular communication network factor 2 0.00633396
IGFBP1 insulin-like growth factor binding protein 1 0.00631378
ALG6 ALG6, alpha-1,3-glucosyltransferase 0.00630422
PAH phenylalanine hydroxylase 0.00629546
CALML5 calmodulin-like 5 0.00628498
SFRP1 secreted frizzled-related protein 1 0.00628049
SIX2 SIX homeobox 2 0.00627837
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.00627473
STEAP3 STEAP family member 3, metalloreductase 0.00625946
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00624357
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.00624086
COL11A1 collagen, type XI, alpha 1 0.00623602
HCRTR1 hypocretin (orexin) receptor 1 0.00622333
TRAPPC8 trafficking protein particle complex 8 0.00622256
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.00620579
KDM5D lysine (K)-specific demethylase 5D 0.00616653
SLPI secretory leukocyte peptidase inhibitor 0.00616141
SUCO SUN domain containing ossification factor 0.00615488
SIK1 salt-inducible kinase 1 0.00613622
GPR137B G protein-coupled receptor 137B 0.00613483
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.00612197
NCOA1 nuclear receptor coactivator 1 0.00611865
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.00611727
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00610596
HCRT hypocretin (orexin) neuropeptide precursor 0.00608248
CD46 CD46 molecule, complement regulatory protein 0.00605455
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00605247
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 0.00603789
SNAI2 snail family zinc finger 2 0.0060362
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.0060249
CD58 CD58 molecule 0.00601837
GCLM glutamate-cysteine ligase, modifier subunit 0.00601734
RO60 Ro60, Y RNA binding protein 0.00601229
MBD2 methyl-CpG binding domain protein 2 0.00600415
GOLGA8A golgin A8 family, member A 0.00600033
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00598712
TFDP1 transcription factor Dp-1 0.00598469
FHOD3 formin homology 2 domain containing 3 0.00597167
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like 0.00596964
WNT5A wingless-type MMTV integration site family, member 5A 0.0059539
LRRC8B leucine rich repeat containing 8 family, member B 0.00592565
FABP4 fatty acid binding protein 4, adipocyte 0.00591291
DNAAF5 dynein, axonemal, assembly factor 5 0.00589709
CYB5R1 cytochrome b5 reductase 1 0.00589308
CKAP4 cytoskeleton-associated protein 4 0.0058844
ADD3 adducin 3 (gamma) 0.00588345
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.00587999
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.0058565
LAPTM4B lysosomal protein transmembrane 4 beta 0.00585285
ARG1 arginase 1 0.00584906
CLIC3 chloride intracellular channel 3 0.00584065
LGALS13 lectin, galactoside-binding, soluble, 13 0.00583674
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.00582166
OSBPL10 oxysterol binding protein-like 10 0.0058137
SRI sorcin 0.00579296
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.00578593
FBXO21 F-box protein 21 0.00578349
DDHD2 DDHD domain containing 2 0.00578189
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 0.0057798
IDO1 indoleamine 2,3-dioxygenase 1 0.0057771
RCAN1 regulator of calcineurin 1 0.00577568
KPNA3 karyopherin alpha 3 (importin alpha 4) 0.00577517
SLF2 SMC5-SMC6 complex localization factor 2 0.00576308
TOR1AIP1 torsin A interacting protein 1 0.0057583
EMC2 ER membrane protein complex subunit 2 0.00575662
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00575096
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.00572754
ATMIN ATM interactor 0.0057234
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.00572024
TMEM165 transmembrane protein 165 0.00571907
OXCT1 3-oxoacid CoA transferase 1 0.00571573
CYB561 cytochrome b561 0.00571188
TFR2 transferrin receptor 2 0.00571148
PALMD palmdelphin 0.0057083
MCTP2 multiple C2 domains, transmembrane 2 0.00570734
JCHAIN joining chain of multimeric IgA and IgM 0.00570621
RSAD2 radical S-adenosyl methionine domain containing 2 0.00570608
RAP2A RAP2A, member of RAS oncogene family 0.00570143
TSLIG3A tRNA splicing ligase complex subunit 3A 0.00569494
LMAN1 lectin, mannose-binding, 1 0.00569144
OPTN optineurin 0.00568794
PIGN phosphatidylinositol glycan anchor biosynthesis, class N 0.00567644
MTDH metadherin 0.00564797
CCSER2 coiled-coil serine-rich protein 2 0.00564606
UXT ubiquitously-expressed, prefoldin-like chaperone 0.0056437
PRKCI protein kinase C, iota 0.00564299
ATP11B ATPase, class VI, type 11B 0.00563469
SPRR3 small proline-rich protein 3 0.00562206
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.00559856
WFS1 Wolfram syndrome 1 (wolframin) 0.00558268
GLS glutaminase 0.00558106
ACVR2A activin A receptor, type IIA 0.00557671
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 0.00557111
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 0.00554952
TP63 tumor protein p63 0.00554503
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.00553777
TUT4 terminal uridylyl transferase 4 0.00553743
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00553406
IQCE IQ motif containing E 0.00553363
TRAPPC10 trafficking protein particle complex 10 0.00552953
GATA2 GATA binding protein 2 0.00552761
PRPF4B pre-mRNA processing factor 4B 0.00552719
CDK14 cyclin-dependent kinase 14 0.00552021
ORC1 origin recognition complex, subunit 1 0.00551315
E2F5 E2F transcription factor 5, p130-binding 0.00550788
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.00549578
KRT13 keratin 13, type I 0.00548578
PHTF2 putative homeodomain transcription factor 2 0.00547828
CFH complement factor H 0.0054546
MYH10 myosin, heavy chain 10, non-muscle 0.00544652
UXS1 UDP-glucuronate decarboxylase 1 0.00544218
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.00542838
GPR87 G protein-coupled receptor 87 0.00542438
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase 0.0054218
TUBB4B tubulin, beta 4B class IVb 0.0054183
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.00541111
USP32P2 ubiquitin specific peptidase 32 pseudogene 2 0.00540239
BTG3 BTG family, member 3 0.00539688
RANBP6 RAN binding protein 6 0.00539513
SLC38A4 solute carrier family 38, member 4 0.00538399
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 0.00537966
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 0.00537864
CLIC5 chloride intracellular channel 5 0.00537221
GZMK granzyme K (granzyme 3; tryptase II) 0.00536693
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 0.00536177
SPAST spastin 0.00535541
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00534865
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00533564
TMCO3 transmembrane and coiled-coil domains 3 0.00532749

decreased expression

Symbol Name Standardized Value
CDC42 cell division cycle 42 -0.0165545
AGR2 anterior gradient 2 -0.0147387
THBS4 thrombospondin 4 -0.0145658
TFF1 trefoil factor 1 -0.0141897
MGP matrix Gla protein -0.0136559
CA2 carbonic anhydrase II -0.0135951
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -0.0118609
IL17RB interleukin 17 receptor B -0.0118568
ADIRF adipogenesis regulatory factor -0.0117518
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.0114787
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0112591
KRT19 keratin 19, type I -0.0111265
LGALS4 lectin, galactoside-binding, soluble, 4 -0.0111259
ASS1 argininosuccinate synthase 1 -0.010742
FHL1 four and a half LIM domains 1 -0.0107209
REG1A regenerating islet-derived 1 alpha -0.0106443
CTSZ cathepsin Z -0.0106273
C2CD5 C2 calcium-dependent domain containing 5 -0.0104756
MUC2 mucin 2, oligomeric mucus/gel-forming -0.0102142
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.0102024
CST3 cystatin C -0.0101391
CRYAB crystallin, alpha B -0.0100354
SPINK4 serine peptidase inhibitor, Kazal type 4 -0.00995158
CRIP1 cysteine-rich protein 1 (intestinal) -0.0097743
F13A1 coagulation factor XIII, A1 polypeptide -0.00973716
MT1E metallothionein 1E -0.00971079
CA12 carbonic anhydrase XII -0.00963034
HSPB8 heat shock 22kDa protein 8 -0.00957696
ZNF721 zinc finger protein 721 -0.00956445
GAB2 GRB2-associated binding protein 2 -0.00949099
HEATR1 HEAT repeat containing 1 -0.00944532
IRS2 insulin receptor substrate 2 -0.00940442
FMOD fibromodulin -0.00932219
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00919924
TSPAN7 tetraspanin 7 -0.00919755
RBM47 RNA binding motif protein 47 -0.00899563
IRF8 interferon regulatory factor 8 -0.0089881
FCGBP Fc fragment of IgG binding protein -0.00898805
HIRA histone cell cycle regulator -0.00897334
MAOA monoamine oxidase A -0.0089466
STC2 stanniocalcin 2 -0.00893681
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.0088813
ACTC1 actin, alpha, cardiac muscle 1 -0.00886357
KRT18 keratin 18, type I -0.00882587
CD93 CD93 molecule -0.00877724
CLCA1 chloride channel accessory 1 -0.00877062
MFAP4 microfibrillar-associated protein 4 -0.00874129
LMNB1 lamin B1 -0.00873073
RGS5 regulator of G-protein signaling 5 -0.00865204
DMBT1 deleted in malignant brain tumors 1 -0.00854313
EIF5A eukaryotic translation initiation factor 5A -0.00854149
VDAC1 voltage-dependent anion channel 1 -0.00850839
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.00849559
CHGB chromogranin B -0.00840574
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.00838699
IFI6 interferon, alpha-inducible protein 6 -0.00827734
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00824851
KCTD12 potassium channel tetramerization domain containing 12 -0.00816862
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00803644
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -0.00799047
PGC progastricsin (pepsinogen C) -0.00795345
GPX3 glutathione peroxidase 3 -0.00794154
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00783205
BAG3 BCL2-associated athanogene 3 -0.00779077
ACKR1 atypical chemokine receptor 1 (Duffy blood group) -0.00778064
UGDH UDP-glucose 6-dehydrogenase -0.00769535
CHRDL1 chordin-like 1 -0.00768254
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00758807
CD14 CD14 molecule -0.0075747
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00754374
CFD complement factor D (adipsin) -0.00748159
IL6ST interleukin 6 signal transducer -0.00747161
AHNAK AHNAK nucleoprotein -0.0073803
OPHN1 oligophrenin 1 -0.00734009
APOLD1 apolipoprotein L domain containing 1 -0.00727775
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.00726213
HOXB6 homeobox B6 -0.00726071
VWF von Willebrand factor -0.00725846
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00725114
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.00724653
MYO5C myosin VC -0.0072302
GPC3 glypican 3 -0.00722892
WFDC2 WAP four-disulfide core domain 2 -0.00722015
REG3A regenerating islet-derived 3 alpha -0.00720725
MEN1 multiple endocrine neoplasia I -0.007195
GJA1 gap junction protein, alpha 1, 43kDa -0.00719023
MYBPC1 myosin binding protein C, slow type -0.00717366
ZW10 zw10 kinetochore protein -0.00714048
DHDDS dehydrodolichyl diphosphate synthase -0.00713685
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle -0.00712711
REEP1 receptor accessory protein 1 -0.00711465
SCD5 stearoyl-CoA desaturase 5 -0.0071049
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00710099
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00709431
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00707201
KLF6 Kruppel-like factor 6 -0.00705597
MT1M metallothionein 1M -0.00703705
GPX2 glutathione peroxidase 2 -0.00700864
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.00700192
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00699254
COL4A2 collagen, type IV, alpha 2 -0.00698891
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) -0.00698294
DDR2 discoidin domain receptor tyrosine kinase 2 -0.00696204
AOC1 amine oxidase, copper containing 1 -0.0069389
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -0.00693623
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -0.00692156
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00691238
F12 coagulation factor XII (Hageman factor) -0.00687854
VSIG4 V-set and immunoglobulin domain containing 4 -0.0068303
DES desmin -0.00682177
ERP29 endoplasmic reticulum protein 29 -0.0068136
CD99 CD99 molecule -0.00680721
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.00679401
SLN sarcolipin -0.00679153
KLF4 Kruppel-like factor 4 (gut) -0.00679002
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00677824
TFPI2 tissue factor pathway inhibitor 2 -0.00675092
S100A10 S100 calcium binding protein A10 -0.0067496
ZBTB35 zinc finger and BTB domain containing 35 -0.0067478
ITGA7 integrin, alpha 7 -0.00673192
KRT8 keratin 8, type II -0.00672876
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -0.00672549
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00670908
CYBB cytochrome b-245, beta polypeptide -0.00670878
IGFBP4 insulin-like growth factor binding protein 4 -0.00670428
DMAC2L distal membrane arm assembly component 2 like -0.00669536
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00667187
CLDN5 claudin 5 -0.00666259
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -0.00665826
MGLL monoglyceride lipase -0.00665158
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -0.00664593
AP1S1 adaptor-related protein complex 1, sigma 1 subunit -0.00662838
TENT5A terminal nucleotidyltransferase 5A -0.00659755
FST follistatin -0.0065971
MID1 midline 1 -0.00658929
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -0.00658852
GLUL glutamate-ammonia ligase -0.00658312
STMN2 stathmin 2 -0.00658205
CLEC11A C-type lectin domain family 11, member A -0.00657993
NPY neuropeptide Y -0.00657977
RPS26 ribosomal protein S26 -0.00657389
EDN3 endothelin 3 -0.00656628
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -0.00656352
SNAP25 synaptosomal-associated protein, 25kDa -0.00656235
CLDN7 claudin 7 -0.0065386
ASRGL1 asparaginase like 1 -0.00653792
OLA1 Obg-like ATPase 1 -0.00653527
TPD52L1 tumor protein D52-like 1 -0.00652824
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00652623
DDIT3 DNA-damage-inducible transcript 3 -0.00652003
OXA1L oxidase (cytochrome c) assembly 1-like -0.0065022
NEFM neurofilament, medium polypeptide -0.00649662
FKBP5 FK506 binding protein 5 -0.00647226
SH3TC1 SH3 domain and tetratricopeptide repeats 1 -0.00647061
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -0.00644417
FGFBP1 fibroblast growth factor binding protein 1 -0.00644051
PYCARD PYD and CARD domain containing -0.00643091
FGFR1 fibroblast growth factor receptor 1 -0.00642667
TPSAB1 tryptase alpha/beta 1 -0.00642151
MX1 MX dynamin-like GTPase 1 -0.00642001
FOXF1 forkhead box F1 -0.00640532
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00639814
TCF7 transcription factor 7 (T-cell specific, HMG-box) -0.00637439
EPS8L3 EPS8-like 3 -0.00634577
GPA33 glycoprotein A33 (transmembrane) -0.00634316
PGD phosphogluconate dehydrogenase -0.00633175
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -0.00630342
RCAN2 regulator of calcineurin 2 -0.00630224
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00629993
XIC X chromosome inactivation center -0.00629828
RNASE6 ribonuclease, RNase A family, k6 -0.00626877
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 -0.00626451
IFITM1 interferon induced transmembrane protein 1 -0.00622314
PQBP1 polyglutamine binding protein 1 -0.00620145
CA4 carbonic anhydrase IV -0.00620032
RBM34 RNA binding motif protein 34 -0.00619826
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.00619099
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit -0.00618771
CORO1C coronin, actin binding protein, 1C -0.00618425
AREG amphiregulin -0.00618368
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00617903
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -0.00617792
APOA1 apolipoprotein A-I -0.00616767
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00614658
MAPT microtubule-associated protein tau -0.00614567
TTC39A tetratricopeptide repeat domain 39A -0.00614539
GRK5 G protein-coupled receptor kinase 5 -0.00614423
GUSBP3 glucuronidase, beta pseudogene 3 -0.00613017
EMP1 epithelial membrane protein 1 -0.00612819
SEPP1 selenoprotein P, plasma, 1 -0.00612091
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0060983
CDC42SE1 CDC42 small effector 1 -0.00608138
PDAP1 PDGFA associated protein 1 -0.0060567
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 -0.0060512
SPON1 spondin 1, extracellular matrix protein -0.0060248
ITPK1 inositol-tetrakisphosphate 1-kinase -0.0060203
ZNF652 zinc finger protein 652 -0.00601372
CDC45 cell division cycle 45 -0.0060085
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.0060049
RNASET2 ribonuclease T2 -0.00600291
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.0059944
EDN1 endothelin 1 -0.00598685
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.0059817
JAM3 junctional adhesion molecule 3 -0.00598117
DCHS1 dachsous cadherin-related 1 -0.0059808
GAS6 growth arrest-specific 6 -0.00598042
RAP1GAP2 RAP1 GTPase activating protein 2 -0.00596651
EFNB2 ephrin-B2 -0.00596243
GLA galactosidase, alpha -0.00593385
COLEC12 collectin sub-family member 12 -0.00593041
CHN2 chimerin 2 -0.0059303
TFF3 trefoil factor 3 (intestinal) -0.00592675
PFDN6 prefoldin subunit 6 -0.00590874
SPARCL1 SPARC-like 1 (hevin) -0.00589416
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -0.0058713
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.00585195
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00579779
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.00579238
PHB prohibitin -0.00576
MYO1B myosin IB -0.00575908
INSR insulin receptor -0.00575904
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -0.00575795
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -0.00574852
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.0057357
CAV1 caveolin 1, caveolae protein, 22kDa -0.00572531
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00569923
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -0.00567733
GPR183 G protein-coupled receptor 183 -0.00567652
HAUS2 HAUS augmin-like complex, subunit 2 -0.00566618
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) -0.00565462
CD248 CD248 molecule, endosialin -0.00565081
TNNT1 troponin T type 1 (skeletal, slow) -0.00564994
MMP3 matrix metallopeptidase 3 -0.00564253
BMP2 bone morphogenetic protein 2 -0.00563706
HSPA1A heat shock 70kDa protein 1A -0.00563525
DDAH2 dimethylarginine dimethylaminohydrolase 2 -0.00562379
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.00562242
PRR11 proline rich 11 -0.00562038
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -0.00561383
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00560585
NPTX2 neuronal pentraxin II -0.00559208
PELI2 pellino E3 ubiquitin protein ligase family member 2 -0.00559091
TESC tescalcin -0.00558028
CNOT2 CCR4-NOT transcription complex, subunit 2 -0.00557482
CLDN15 claudin 15 -0.0055692
INSL3 insulin-like 3 (Leydig cell) -0.00556819
CARD10 caspase recruitment domain family, member 10 -0.00556495
SPRY4 sprouty homolog 4 (Drosophila) -0.0055637
SPRY2 sprouty homolog 2 (Drosophila) -0.00555951