FOXF2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description forkhead box F2|FOXF2 encodes forkhead box F2, one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2295)
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Genes

360 genes differentially expressed following the FOXF2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
GJA3 gap junction protein, alpha 3, 46kDa 2.47277
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 2.47277
RSPO3 R-spondin 3 2.47277
SLC30A2 solute carrier family 30 (zinc transporter), member 2 2.47277
DEPP1 DEPP autophagy regulator 1 2.47277
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 2.47277
PBOV1 prostate and breast cancer overexpressed 1 2.47277
FAM221B family with sequence similarity 221, member B 2.47277
RAPSN receptor-associated protein of the synapse 2.47277
GFPT2 glutamine-fructose-6-phosphate transaminase 2 2.47277
SLC15A5 solute carrier family 15, member 5 2.47277
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 2.47277
PLIN1 perilipin 1 2.47277
SIX2 SIX homeobox 2 2.47277
HLX H2.0-like homeobox 2.47277
SRPRA SRP receptor subunit alpha 2.47277
CST11 cystatin 11 2.47277
RASL10A RAS-like, family 10, member A 2.47277
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 2.47277
CHRND cholinergic receptor, nicotinic, delta (muscle) 2.47277
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 2.47277
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7 2.47277
TDRD6 tudor domain containing 6 2.47277
DYNLT4 dynein light chain Tctex-type 4 2.47277
PMCH pro-melanin-concentrating hormone 2.47277
CIBAR2 CBY1 interacting BAR domain containing 2 2.47277
DGKH diacylglycerol kinase, eta 2.47277
CCDC87 coiled-coil domain containing 87 2.47277
GALK2 galactokinase 2 2.47277
SCIN scinderin 2.47277
POU2AF2 POU class 2 homeobox associating factor 2 2.47277
TMEM184A transmembrane protein 184A 2.47277
CD33 CD33 molecule 2.47277
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.47277
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 2.47277
KCNU1 potassium channel, subfamily U, member 1 2.47277
LCN12 lipocalin 12 2.47277
CD68 CD68 molecule 2.47277
ACP4 acid phosphatase 4 2.47277
SIRAL2 SIR2 antiphage like 2 2.47277
HBZ hemoglobin, zeta 2.47277
TBATA thymus, brain and testes associated 2.47277
AIRE autoimmune regulator 2.47277
MAS1 MAS1 proto-oncogene, G protein-coupled receptor 2.47277
PRR29 proline rich 29 2.47277
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 2.47277
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 2.47277
OOSP1 oocyte secreted protein 1, pseudogene 2.47277
PTH parathyroid hormone 2.47277
C7 complement component 7 2.47277
ALG10B ALG10B, alpha-1,2-glucosyltransferase 2.47277
SPDYC speedy/RINGO cell cycle regulator family member C 2.47277
RASAL3 RAS protein activator like 3 2.47277
C1QTNF9 C1q and tumor necrosis factor related protein 9 2.47277
SLAMF1 signaling lymphocytic activation molecule family member 1 2.47277
GZMM granzyme M (lymphocyte met-ase 1) 2.47277
FGFBP2 fibroblast growth factor binding protein 2 2.47277
LRRC73 leucine rich repeat containing 73 2.47277
CNTN6 contactin 6 2.47277
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 2.47277
GRID2 glutamate receptor, ionotropic, delta 2 2.47277
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.47277
XKR3 XK, Kell blood group complex subunit-related family, member 3 2.47277
OR52E5 olfactory receptor, family 52, subfamily E, member 5 2.47277
GPR37L1 G protein-coupled receptor 37 like 1 2.47277
FAM228A family with sequence similarity 228, member A 2.47277
GATA5 GATA binding protein 5 2.47277
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 2.47277
ROPN1L rhophilin associated tail protein 1-like 2.47277
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 2.47277
TMEM98 transmembrane protein 98 2.47277
PCDHA1 protocadherin alpha 1 2.47277
IL36G interleukin 36, gamma 2.47277
GLP2R glucagon-like peptide 2 receptor 2.47277
RAET1G retinoic acid early transcript 1G 2.47277
FABP9 fatty acid binding protein 9, testis 2.47277
PDILT protein disulfide isomerase-like, testis expressed 2.47277
GPR4 G protein-coupled receptor 4 2.47277
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.47277
TUBA3E tubulin, alpha 3e 2.47277
MAGEB1 melanoma antigen family B1 2.47277
DMTF1 cyclin D binding myb-like transcription factor 1 2.47277
IL6 interleukin 6 2.47277
HPSE heparanase 2.47277
CXCL16 chemokine (C-X-C motif) ligand 16 2.47277
SPMIP7 sperm microtubule inner protein 7 2.47277
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 2.47277
GOLGA6L4 golgin A6 family-like 4 2.47277
OR8D4 olfactory receptor, family 8, subfamily D, member 4 2.47277
BICD1 bicaudal D homolog 1 (Drosophila) 2.47277
WNT11 wingless-type MMTV integration site family, member 11 2.47277
TSSK4 testis-specific serine kinase 4 2.47277
KRT13 keratin 13, type I 2.47277
PCP2 Purkinje cell protein 2 2.47277
TPSG1 tryptase gamma 1 2.47277
LRRIQ3 leucine-rich repeats and IQ motif containing 3 2.47277
C2ORF66 chromosome 2 open reading frame 66 2.47277
KLHL41 kelch-like family member 41 2.47277
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 2.47277
H2BK1 H2B.K variant histone 1 2.47277
PRM1 protamine 1 2.47277
SPINK9 serine peptidase inhibitor, Kazal type 9 2.47277
PAGE4 P antigen family, member 4 (prostate associated) 2.47277
GLOD5 glyoxalase domain containing 5 2.47277
LRTM2 leucine-rich repeats and transmembrane domains 2 2.47277
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 2.47277
NGB neuroglobin 2.47277
PDCL2 phosducin-like 2 2.47277
TASP1 taspase, threonine aspartase, 1 2.47277
LRRC46 leucine rich repeat containing 46 2.47277
KCNK3 potassium channel, two pore domain subfamily K, member 3 2.47277
KCNK7 potassium channel, two pore domain subfamily K, member 7 2.47277
CLIC5 chloride intracellular channel 5 2.47277
IGFBP1 insulin-like growth factor binding protein 1 2.47277
MAN2A1 mannosidase, alpha, class 2A, member 1 2.47277
SMPX small muscle protein, X-linked 2.47277
DRD5 dopamine receptor D5 2.47277
CLEC9A C-type lectin domain family 9, member A 2.47277
DMRT3 doublesex and mab-3 related transcription factor 3 2.47277
VAV1 vav 1 guanine nucleotide exchange factor 2.47277
CIMIP1 ciliary microtubule inner protein 1 2.47277
PGR progesterone receptor 2.47277
NKX6-2 NK6 homeobox 2 2.47277
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.47277
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 2.47277
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 2.47277
CFH complement factor H 2.47277
ANKRD55 ankyrin repeat domain 55 2.47277
PRR35 proline rich 35 2.47277
DENND2A DENN/MADD domain containing 2A 2.47277
RUMY3 RUMY family member 3 2.47277
VWA3B von Willebrand factor A domain containing 3B 2.47277
RRH retinal pigment epithelium-derived rhodopsin homolog 2.47277
C17ORF99 chromosome 17 open reading frame 99 2.47277
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 2.47277
RGCC regulator of cell cycle 2.47277
DSP desmoplakin 2.47277
RICTOR RPTOR independent companion of MTOR, complex 2 2.47277
HK3 hexokinase 3 (white cell) 2.47277
SAMHD1 SAM domain and HD domain 1 2.47277
ZNF474 zinc finger protein 474 2.47277
TGM7 transglutaminase 7 2.47277
C4BPA complement component 4 binding protein, alpha 2.47277
OR52P1 olfactory receptor family 52 subfamily P member 1 (gene/pseudogene) 2.47277
MAGEA12 melanoma antigen family A12 2.47277
FOXP3 forkhead box P3 2.47277
GCM2 glial cells missing homolog 2 (Drosophila) 2.47277
CLCA1 chloride channel accessory 1 2.47277
LRRC74B leucine rich repeat containing 74B 2.47277
CTXND1 cortexin domain containing 1 2.47277
PLGLB2 plasminogen-like B2 2.47277
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.47277
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.47277
SRARP steroid receptor associated and regulated protein 2.47277
TCF21 transcription factor 21 2.47277
HSPB9 heat shock protein, alpha-crystallin-related, B9 2.47277
POU3F2 POU class 3 homeobox 2 2.47277
MEPCE methylphosphate capping enzyme 2.47277
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 2.47277
TMEM8B transmembrane protein 8B 2.47277
OXER1 oxoeicosanoid (OXE) receptor 1 2.47277
GPR17 G protein-coupled receptor 17 2.47277
AMER2 APC membrane recruitment protein 2 2.47277
PADI1 peptidyl arginine deiminase, type I 2.47277
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 2.47277
SMIM31 small integral membrane protein 31 2.47277
CPB1 carboxypeptidase B1 (tissue) 2.47277
ZNF593OS ZNF593 opposite strand 2.47277
C4ORF51 chromosome 4 open reading frame 51 2.46733
CD177 CD177 molecule 2.45576
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 2.45576
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 2.45062
LRRC75A leucine rich repeat containing 75A 2.41352
UBE4B ubiquitination factor E4B 2.40393
FBXL22 F-box and leucine-rich repeat protein 22 2.39073
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 2.39073
ZNF446 zinc finger protein 446 2.39027
ZNF317 zinc finger protein 317 2.36604
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 2.36278
NOPCHAP1 NOP protein chaperone 1 2.35575
MCU mitochondrial calcium uniporter 2.34834
RAB11FIP1 RAB11 family interacting protein 1 (class I) 2.3434
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 2.34079
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 2.33299
CEP43 centrosomal protein 43 2.32921
ODF2 outer dense fiber of sperm tails 2 2.32412
PODNL1 podocan-like 1 2.32253
TAS1R1 taste receptor, type 1, member 1 2.32253
SYT14 synaptotagmin XIV 2.31949
MRPL4 mitochondrial ribosomal protein L4 2.31507
SOX21 SRY (sex determining region Y)-box 21 2.31471
PEG10 paternally expressed 10 2.2998
MST1R macrophage stimulating 1 receptor 2.29372
FKBPL FK506 binding protein like 2.28336
PTPRU protein tyrosine phosphatase, receptor type, U 2.27746
ZNF808 zinc finger protein 808 2.27617
ZSCAN9 zinc finger and SCAN domain containing 9 2.25197
SHPK sedoheptulokinase 2.24763
LPCAT1 lysophosphatidylcholine acyltransferase 1 2.24763
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 2.23086
PRRC2A proline-rich coiled-coil 2A 2.22688
TBC1D7-LOC100130357 TBC1D7-LOC100130357 readthrough 2.19856
THUMPD2 THUMP domain containing 2 2.18447
STK33 serine/threonine kinase 33 2.16804
BICRAL BICRA like chromatin remodeling complex associated protein 2.16019
PTPN6 protein tyrosine phosphatase, non-receptor type 6 2.15557
KIF14 kinesin family member 14 2.14287
HAUS4 HAUS augmin-like complex, subunit 4 2.14013
ANKRD13C ankyrin repeat domain 13C 2.13886
BRSK2 BR serine/threonine kinase 2 2.13847
SEZ6 seizure related 6 homolog (mouse) 2.13622
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) 2.11879
CTSA cathepsin A 2.1154
DNAH5 dynein, axonemal, heavy chain 5 2.1154
COL4A1 collagen, type IV, alpha 1 2.10455
MVP major vault protein 2.10455
ZNF235 zinc finger protein 235 2.09782
TJP2 tight junction protein 2 2.09335
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 2.08439
TP53I3 tumor protein p53 inducible protein 3 2.07422
CPEB2 cytoplasmic polyadenylation element binding protein 2 2.06706
INCENP inner centromere protein antigens 135/155kDa 2.06199
THEM6 thioesterase superfamily member 6 2.05612
HAP1 huntingtin-associated protein 1 2.04575
MAP2K5-DT MAP2K5 divergent transcript 2.03234
RILP Rab interacting lysosomal protein 2.03101
KALRN kalirin, RhoGEF kinase 2.03101
CLEC11A C-type lectin domain family 11, member A 2.02947
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 2.02136
MED13 mediator complex subunit 13 2.021
COL25A1 collagen, type XXV, alpha 1 2.01609
ZSCAN12 zinc finger and SCAN domain containing 12 2.01304
MCF2 MCF.2 cell line derived transforming sequence 2.01078
PPP1R3E protein phosphatase 1, regulatory subunit 3E 2.00499

decreased expression

Symbol Name Standardized Value
LOC107986837 uncharacterized LOC107986837 -2.47277
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C -2.47277
VSTM2B V-set and transmembrane domain containing 2B -2.47277
ARID3A AT rich interactive domain 3A (BRIGHT-like) -2.47277
LBP lipopolysaccharide binding protein -2.47277
GPR21 G protein-coupled receptor 21 -2.47277
THRSP thyroid hormone responsive -2.47277
PTGER4 prostaglandin E receptor 4 (subtype EP4) -2.47277
NPIPA8 nuclear pore complex interacting protein family, member A8 -2.47277
ACOT12 acyl-CoA thioesterase 12 -2.47277
GALR3 galanin receptor 3 -2.47277
TPPP tubulin polymerization promoting protein -2.47277
SPON2 spondin 2, extracellular matrix protein -2.47277
LHX1 LIM homeobox 1 -2.47277
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 -2.47277
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 -2.47277
CD96 CD96 molecule -2.47277
PRB2 proline-rich protein BstNI subfamily 2 -2.47277
FAM240C family with sequence similarity 240 member C -2.47277
CCDC163 CCDC163 homolog -2.47277
CLDN15 claudin 15 -2.47277
SPC25 SPC25, NDC80 kinetochore complex component -2.47277
PXDC1 PX domain containing 1 -2.47277
WNT9B wingless-type MMTV integration site family, member 9B -2.47277
FOXI3 forkhead box I3 -2.47277
KCNT1 potassium channel, sodium activated subfamily T, member 1 -2.47277
SCRT2 scratch family zinc finger 2 -2.47277
CATSPER3 cation channel, sperm associated 3 -2.47277
LDHAL6A lactate dehydrogenase A-like 6A -2.47277
CLDN5 claudin 5 -2.47277
CFAP99 cilia and flagella associated protein 99 -2.47277
ARL5C ADP-ribosylation factor-like 5C -2.47277
ADAM21 ADAM metallopeptidase domain 21 -2.47277
ABHD3 abhydrolase domain containing 3 -2.47277
DAPK1 death-associated protein kinase 1 -2.47277
FBXO40 F-box protein 40 -2.47277
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) -2.47277
MAGEB17 melanoma antigen family B17 -2.47277
FMO1 flavin containing monooxygenase 1 -2.47277
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 -2.47277
RNFT2 ring finger protein, transmembrane 2 -2.47277
BTNL2 butyrophilin-like 2 -2.47277
MYO3B myosin IIIB -2.47277
RSL1D1 ribosomal L1 domain containing 1 -2.47277
PRPH2 peripherin 2 (retinal degeneration, slow) -2.47277
AHRR aryl-hydrocarbon receptor repressor -2.47277
BCL3 B-cell CLL/lymphoma 3 -2.47277
SHISA8 shisa family member 8 -2.47277
MSMP microseminoprotein, prostate associated -2.47277
EFCC1 EF-hand and coiled-coil domain containing 1 -2.47277
LMBR1L limb development membrane protein 1-like -2.47277
MRPS9 mitochondrial ribosomal protein S9 -2.47277
TBRG1 transforming growth factor beta regulator 1 -2.44222
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria -2.43663
INA internexin neuronal intermediate filament protein, alpha -2.42607
ADRA1D adrenoceptor alpha 1D -2.39648
NOS2 nitric oxide synthase 2, inducible -2.39648
ZNF723 zinc finger protein 723 -2.39278
RLN2 relaxin 2 -2.39027
ALG12 ALG12, alpha-1,6-mannosyltransferase -2.39027
CAMLG calcium modulating ligand -2.39027
MAPRE1 microtubule-associated protein, RP/EB family, member 1 -2.36644
SYT11 synaptotagmin XI -2.35125
PYGM phosphorylase, glycogen, muscle -2.34834
ZSCAN5A zinc finger and SCAN domain containing 5A -2.33599
VCX3B variable charge, X-linked 3B -2.33492
BRICD5 BRICHOS domain containing 5 -2.33492
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -2.32412
EGLN1 egl-9 family hypoxia-inducible factor 1 -2.32412
ZCCHC2 zinc finger, CCHC domain containing 2 -2.30458
PLPPR5 phospholipid phosphatase related 5 -2.28336
PDLIM1 PDZ and LIM domain 1 -2.28336
CRB2 crumbs family member 2 -2.27617
CARS1 cysteinyl-tRNA synthetase 1 -2.27617
ARHGAP17 Rho GTPase activating protein 17 -2.26369
NUTF2 nuclear transport factor 2 -2.26323
RETREG2 reticulophagy regulator family member 2 -2.2613
RCC2 regulator of chromosome condensation 2 -2.25097
C5 complement component 5 -2.22411
CETN2 centrin, EF-hand protein, 2 -2.22175
RPL7A ribosomal protein L7a -2.21871
TRIM5 tripartite motif containing 5 -2.21612
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21 -2.21266
UQCC6 ubiquinol-cytochrome c reductase complex assembly factor 6 -2.21038
SRSF2 serine/arginine-rich splicing factor 2 -2.20128
STX1B syntaxin 1B -2.19109
PPDPF pancreatic progenitor cell differentiation and proliferation factor -2.17465
TAGLN transgelin -2.17465
TLR2 toll-like receptor 2 -2.17465
FLACC1 flagellum associated containing coiled-coil domains 1 -2.17465
MPZL2 myelin protein zero-like 2 -2.17465
ZNF471 zinc finger protein 471 -2.17465
CENATAC centrosomal AT-AC splicing factor -2.16606
PCDHA4 protocadherin alpha 4 -2.16606
CEP57 centrosomal protein 57kDa -2.15096
C1ORF50 chromosome 1 open reading frame 50 -2.14935
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) -2.14718
CCND2 cyclin D2 -2.14013
RTN3 reticulon 3 -2.13886
RPLP0 ribosomal protein, large, P0 -2.13886
AKAP8L A kinase (PRKA) anchor protein 8-like -2.1265
UROS uroporphyrinogen III synthase -2.12149
ZKSCAN2 zinc finger with KRAB and SCAN domains 2 -2.1136
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -2.11196
DTD2 D-tyrosyl-tRNA deacylase 2 (putative) -2.11161
CNTN2 contactin 2 (axonal) -2.10157
CEP152 centrosomal protein 152kDa -2.09782
NDRG2 NDRG family member 2 -2.09335
TUBA4B tubulin, alpha 4b -2.09335
SELENOM selenoprotein M -2.09335
BEND6 BEN domain containing 6 -2.08369
SLC16A4 solute carrier family 16, member 4 -2.06022
PGM2L1 phosphoglucomutase 2-like 1 -2.05215
KLHL13 kelch-like family member 13 -2.05181
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -2.04575
GLRX2 glutaredoxin 2 -2.03101
SREBF1 sterol regulatory element binding transcription factor 1 -2.02943
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -2.02943
POLR3B polymerase (RNA) III (DNA directed) polypeptide B -2.02943
CALD1 caldesmon 1 -2.02832
GCNT7 glucosaminyl (N-acetyl) transferase family member 7 -2.02658
CDC50A cell division cycle 50 P4-ATPase accessory subunit A -2.01377
TIPE3 TNF alpha induced protein 8 like 3 -2.01078
CCDC124 coiled-coil domain containing 124 -2.00647
RPA3 replication protein A3, 14kDa -2.00647
CCDC141 coiled-coil domain containing 141 -2.00521