FOXI1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description forkhead box I1|This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it is possible that this gene plays an important role in the development of the cochlea and vestibulum, as well as embryogenesis. Mutations in this gene may be associated with the common cavity phenotype. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2299)
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Genes

314 genes differentially expressed following the FOXI1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PI16 peptidase inhibitor 16 2.34088
IQCJ IQ motif containing J 2.34088
DRICH1 aspartate-rich 1 2.34088
SKOR2 SKI family transcriptional corepressor 2 2.34088
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 2.34088
MUC5B mucin 5B, oligomeric mucus/gel-forming 2.34088
FOXR1 forkhead box R1 2.34088
OR2J2 olfactory receptor, family 2, subfamily J, member 2 2.34088
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 2.34088
PAX5 paired box 5 2.34088
PRL prolactin 2.34088
IL5RA interleukin 5 receptor, alpha 2.34088
SIRPB2 signal-regulatory protein beta 2 2.34088
SLC46A2 solute carrier family 46, member 2 2.34088
IGFL4 IGF-like family member 4 2.34088
GNLY granulysin 2.34088
CD1C CD1c molecule 2.34088
SPINK6 serine peptidase inhibitor, Kazal type 6 2.34088
NANOS2 nanos homolog 2 (Drosophila) 2.34088
NXPH4 neurexophilin 4 2.34088
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 2.34088
NCF1 neutrophil cytosolic factor 1 2.34088
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 2.34088
MUSK muscle, skeletal, receptor tyrosine kinase 2.34088
GRIA2 glutamate receptor, ionotropic, AMPA 2 2.34088
CCL3L3 chemokine (C-C motif) ligand 3-like 3 2.34088
ADAT3 adenosine deaminase, tRNA-specific 3 2.34088
LRRIQ4 leucine-rich repeats and IQ motif containing 4 2.34088
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial 2.34088
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 2.34088
LGALS9 lectin, galactoside-binding, soluble, 9 2.34088
MLF2 myeloid leukemia factor 2 2.34088
REM1 RAS (RAD and GEM)-like GTP-binding 1 2.34088
OR2B11 olfactory receptor, family 2, subfamily B, member 11 2.34088
SPACA3 sperm acrosome associated 3 2.34088
MYL5 myosin, light chain 5, regulatory 2.34088
GTPBP3 GTP binding protein 3 (mitochondrial) 2.34088
ANKK1 ankyrin repeat and kinase domain containing 1 2.34088
CCT8 chaperonin containing TCP1, subunit 8 (theta) 2.34088
DIRAS2 DIRAS family, GTP-binding RAS-like 2 2.34088
GPR22 G protein-coupled receptor 22 2.34088
MYCT1 myc target 1 2.34088
HCRTR2 hypocretin (orexin) receptor 2 2.34088
ANKRD34C ankyrin repeat domain 34C 2.34088
OTUD6A OTU deubiquitinase 6A 2.34088
BIRC3 baculoviral IAP repeat containing 3 2.34088
C9ORF152 chromosome 9 open reading frame 152 2.34088
CIMIP2C ciliary microtubule inner protein 2C 2.34088
THEMIS thymocyte selection associated 2.34088
TBC1D3I TBC1 domain family member 3I 2.34088
KY kyphoscoliosis peptidase 2.34088
HBG2 hemoglobin, gamma G 2.34088
CAPN9 calpain 9 2.34088
CCER2 coiled-coil glutamate-rich protein 2 2.34088
FRG2C FSHD region gene 2 family, member C 2.34088
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) 2.34088
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 2.34088
SMPX small muscle protein, X-linked 2.34088
TTC23L tetratricopeptide repeat domain 23-like 2.34088
GCSAM germinal center-associated, signaling and motility 2.34088
GBP3 guanylate binding protein 3 2.34088
GBP4 guanylate binding protein 4 2.34088
AGA-DT AGA divergent transcript 2.34088
SPAAR small regulatory polypeptide of amino acid response 2.34088
ACP4 acid phosphatase 4 2.34088
GARIN5B golgi associated RAB2 interactor family member 5B 2.34088
CATSPERZ catsper channel auxiliary subunit zeta 2.34088
KASH5 KASH domain containing 5 2.34088
MSANTD5 Myb/SANT DNA binding domain containing 5 2.34088
ACOD1 aconitate decarboxylase 1 2.34088
SLURP2 secreted LY6/PLAUR domain containing 2 2.34088
RAB5IF RAB5 interacting factor 2.34088
GPR85 G protein-coupled receptor 85 2.34088
NCLN nicalin 2.34088
ABHD15 abhydrolase domain containing 15 2.34088
PANX3 pannexin 3 2.34088
PVRIG poliovirus receptor related immunoglobulin domain containing 2.34088
CLTA clathrin, light chain A 2.34088
CES3 carboxylesterase 3 2.34088
SIX3 SIX homeobox 3 2.34088
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 2.34088
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 2.34088
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.34088
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.34088
SLC5A9 solute carrier family 5 (sodium/sugar cotransporter), member 9 2.34088
DSG1 desmoglein 1 2.34088
AGA aspartylglucosaminidase 2.34088
ALG10B ALG10B, alpha-1,2-glucosyltransferase 2.34088
BARX2 BARX homeobox 2 2.34088
TACR2 tachykinin receptor 2 2.34088
C1QL2 complement component 1, q subcomponent-like 2 2.34088
TBX5 T-box 5 2.34088
SCRT1 scratch family zinc finger 1 2.34088
NPIPB9 nuclear pore complex interacting protein family, member B9 2.34088
CD79A CD79a molecule, immunoglobulin-associated alpha 2.34088
ANXA10 annexin A10 2.34088
C3ORF80 chromosome 3 open reading frame 80 2.34088
BMF Bcl2 modifying factor 2.34088
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 2.34088
IFNL4 interferon, lambda 4 (gene/pseudogene) 2.34088
OR56A4 olfactory receptor, family 56, subfamily A, member 4 2.34088
EDN3 endothelin 3 2.34088
SUPT20HL2 suppressor of Ty 20 homolog (S. cerevisiae)-like 2 2.34088
GCGR glucagon receptor 2.34088
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 2.34088
POF1B premature ovarian failure, 1B 2.34088
KLHL6 kelch-like family member 6 2.34088
THTPA thiamine triphosphatase 2.34088
RBMXL1 RNA binding motif protein, X-linked-like 1 2.34088
LY96 lymphocyte antigen 96 2.34088
DMRT1 doublesex and mab-3 related transcription factor 1 2.34088
PRSS55 protease, serine, 55 2.34088
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 2.34088
CIDEC cell death-inducing DFFA-like effector c 2.34088
SMYD1 SET and MYND domain containing 1 2.34088
STAB2 stabilin 2 2.34088
KCNK4 potassium channel, two pore domain subfamily K, member 4 2.34088
HAMP hepcidin antimicrobial peptide 2.34088
ADORA1 adenosine A1 receptor 2.34088
CLRN1 clarin 1 2.34088
HM13 histocompatibility (minor) 13 2.34088
TEKT5 tektin 5 2.34088
TRIM50 tripartite motif containing 50 2.34088
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 2.34088
TTC9B tetratricopeptide repeat domain 9B 2.34088
IL1B interleukin 1, beta 2.34088
C2CD4C C2 calcium-dependent domain containing 4C 2.34088
ALOXE3 arachidonate lipoxygenase 3 2.34088
COL17A1 collagen, type XVII, alpha 1 2.34088
SERINC4 serine incorporator 4 2.34088
KLK5 kallikrein-related peptidase 5 2.34088
CDRT15L2 CMT1A duplicated region transcript 15-like 2 2.34088
CTAGE9 CTAGE family, member 9 2.34088
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 2.34088
KLF1 Kruppel-like factor 1 (erythroid) 2.34088
BPIFB1 BPI fold containing family B, member 1 2.34088
SLC31A2 solute carrier family 31 (copper transporter), member 2 2.34088
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.34088
PRSS54 protease, serine, 54 2.34088
PRSS57 protease, serine, 57 2.34088
RAVER2 ribonucleoprotein, PTB-binding 2 2.34088
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 2.34088
PATL2 protein associated with topoisomerase II homolog 2 (yeast) 2.34088
TMPRSS13 transmembrane protease, serine 13 2.34088
TMEM156 transmembrane protein 156 2.34088
HPGDS hematopoietic prostaglandin D synthase 2.34088
PCDHGA4 protocadherin gamma subfamily A, 4 2.34088
RNF148 ring finger protein 148 2.34088
ARHGAP40 Rho GTPase activating protein 40 2.34088
PPP1R3F protein phosphatase 1, regulatory subunit 3F 2.34088
ANGPTL7 angiopoietin-like 7 2.34088
FAM161B family with sequence similarity 161, member B 2.34088
RNASE6 ribonuclease, RNase A family, k6 2.34088
UFSP1 UFM1-specific peptidase 1 (non-functional) 2.34088
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 2.34088
AMPD1 adenosine monophosphate deaminase 1 2.34088
PDK4 pyruvate dehydrogenase kinase, isozyme 4 2.34088
GJC2 gap junction protein, gamma 2, 47kDa 2.34088
ZPBP zona pellucida binding protein 2.34088
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 2.34088
FOXP3 forkhead box P3 2.34088
SYTL4 synaptotagmin-like 4 2.34088
IER5L immediate early response 5-like 2.34088
ALOX15B arachidonate 15-lipoxygenase, type B 2.34088
PRH2 proline-rich protein HaeIII subfamily 2 2.34088
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 2.34088
TMEM31 transmembrane protein 31 2.34088
AOC3 amine oxidase, copper containing 3 2.34088
CARNS1 carnosine synthase 1 2.34088
SLITRK1 SLIT and NTRK-like family, member 1 2.34088
DMTN dematin actin binding protein 2.34088
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 2.34088
EFCAB10 EF-hand calcium binding domain 10 2.34088
RILPL1 Rab interacting lysosomal protein-like 1 2.34088
PRTN3 proteinase 3 2.34088
PTCRA pre T-cell antigen receptor alpha 2.34088
CTSA cathepsin A 2.34088
MST1 macrophage stimulating 1 2.34088
VSIR V-set immunoregulatory receptor 2.33099
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 2.33099
RHCG Rh family, C glycoprotein 2.29679
NT5C3A 5'-nucleotidase, cytosolic IIIA 2.29679
RIC8A RIC8 guanine nucleotide exchange factor A 2.29679
RNF222 ring finger protein 222 2.29679
ASMT acetylserotonin O-methyltransferase 2.29679
FETUB fetuin B 2.29679
GCC2 GRIP and coiled-coil domain containing 2 2.29679
RGPD4 RANBP2-like and GRIP domain containing 4 2.29679
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 2.29679
KIAA1191 KIAA1191 2.28614
EMILIN2 elastin microfibril interfacer 2 2.28614
RPL22L1 ribosomal protein L22-like 1 2.27877
SAR1B secretion associated, Ras related GTPase 1B 2.24787
IFT52 intraflagellar transport 52 2.24613
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.23915
CORO1B coronin, actin binding protein, 1B 2.23324
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4 2.23324
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis) 2.23094
SETX senataxin 2.20738
TAMM41 TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae) 2.19259
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.19259
EMD emerin 2.18892
CREG2 cellular repressor of E1A-stimulated genes 2 2.18892
ZCRB1 zinc finger CCHC-type and RNA binding motif 1 2.18408
HIRA histone cell cycle regulator 2.18163
IRAK1 interleukin-1 receptor-associated kinase 1 2.18163
AMDHD2 amidohydrolase domain containing 2 2.1771
LSM10 LSM10, U7 small nuclear RNA associated 2.16088
KIF7 kinesin family member 7 2.15946
PNP purine nucleoside phosphorylase 2.14672
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 2.14597
KSR1 kinase suppressor of ras 1 2.14432
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 2.13885
POLI polymerase (DNA directed) iota 2.13533
ZNF182 zinc finger protein 182 2.13208
MAP1S microtubule-associated protein 1S 2.09949
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 2.07645
M1AP meiosis 1 associated protein 2.07125
PTGES prostaglandin E synthase 2.0692
ELOA elongin A 2.06135
PIAS3 protein inhibitor of activated STAT, 3 2.04867
PARL presenilin associated, rhomboid-like 2.03321
NR2C1 nuclear receptor subfamily 2, group C, member 1 2.03321
SCG5 secretogranin V 2.03321
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 2.02754
SCAMP4 secretory carrier membrane protein 4 2.00801
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 2.00046

decreased expression

Symbol Name Standardized Value
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -2.34088
THAP9 THAP domain containing 9 -2.34088
EPSTI1 epithelial stromal interaction 1 (breast) -2.34088
RABGGTA Rab geranylgeranyltransferase, alpha subunit -2.34088
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -2.34088
C8ORF58 chromosome 8 open reading frame 58 -2.34088
POLQ polymerase (DNA directed), theta -2.34088
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa -2.34088
WDFY3 WD repeat and FYVE domain containing 3 -2.34088
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 -2.34088
PYGM phosphorylase, glycogen, muscle -2.34088
IL17C interleukin 17C -2.34088
ZNF641 zinc finger protein 641 -2.34088
UPK3B uroplakin 3B -2.34088
CHST13 carbohydrate (chondroitin 4) sulfotransferase 13 -2.34088
FLT3 fms-related tyrosine kinase 3 -2.34088
INSYN2B inhibitory synaptic factor family member 2B -2.34088
LARS1 leucyl-tRNA synthetase 1 -2.34088
UBA3 ubiquitin-like modifier activating enzyme 3 -2.34088
DUSP2 dual specificity phosphatase 2 -2.34088
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -2.34088
ACTR6 ARP6 actin-related protein 6 homolog (yeast) -2.32298
FAM186B family with sequence similarity 186, member B -2.29679
ZNF222 zinc finger protein 222 -2.29679
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.29679
LHX1 LIM homeobox 1 -2.29679
CFAP141 cilia and flagella associated protein 141 -2.29679
LOC124903233 uncharacterized LOC124903233 -2.29679
TNS4 tensin 4 -2.29679
ALOX15 arachidonate 15-lipoxygenase -2.29679
SLC22A10 solute carrier family 22, member 10 -2.29679
TRPC4 transient receptor potential cation channel, subfamily C, member 4 -2.29679
CALCA calcitonin-related polypeptide alpha -2.29679
C19ORF67 chromosome 19 open reading frame 67 -2.29679
NR2C2 nuclear receptor subfamily 2, group C, member 2 -2.29679
OVOL3 ovo-like zinc finger 3 -2.29679
GUCY2D guanylate cyclase 2D, membrane (retina-specific) -2.29679
TFF3 trefoil factor 3 (intestinal) -2.29679
CLEC19A C-type lectin domain family 19, member A -2.29679
SYTL3 synaptotagmin-like 3 -2.29679
FAM177B family with sequence similarity 177, member B -2.29679
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) -2.29679
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -2.29679
AGXT2 alanine--glyoxylate aminotransferase 2 -2.29679
VWA7 von Willebrand factor A domain containing 7 -2.29679
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) -2.29679
ERMN ermin, ERM-like protein -2.29679
SIDT1 SID1 transmembrane family, member 1 -2.29679
CCDC172 coiled-coil domain containing 172 -2.29679
FKBP1C FK506 binding protein 1C -2.29679
C11ORF16 chromosome 11 open reading frame 16 -2.29679
ZNF844 zinc finger protein 844 -2.29679
COL11A2 collagen, type XI, alpha 2 -2.29679
DNM3 dynamin 3 -2.296
NECAB2 N-terminal EF-hand calcium binding protein 2 -2.29217
C3ORF70 chromosome 3 open reading frame 70 -2.28614
OTUD7B OTU deubiquitinase 7B -2.27849
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 -2.27191
GUF1 GUF1 GTPase homolog (S. cerevisiae) -2.26492
RPTOR regulatory associated protein of MTOR, complex 1 -2.26175
BCL2L10 BCL2-like 10 (apoptosis facilitator) -2.24734
TMEM229A transmembrane protein 229A -2.24734
TAFA5 TAFA chemokine like family member 5 -2.24734
PIWIL2 piwi-like RNA-mediated gene silencing 2 -2.23324
KLF8 Kruppel-like factor 8 -2.22425
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.21634
MED18 mediator complex subunit 18 -2.21346
GP6 glycoprotein VI (platelet) -2.19259
ATP11A ATPase, class VI, type 11A -2.19259
ZNF274 zinc finger protein 274 -2.19181
CELF2 CUGBP, Elav-like family member 2 -2.18284
TLR3 toll-like receptor 3 -2.18284
SLC35F1 solute carrier family 35, member F1 -2.18163
BCAS4 breast carcinoma amplified sequence 4 -2.18163
AIP aryl hydrocarbon receptor interacting protein -2.18163
MEX3D mex-3 RNA binding family member D -2.18163
PLD5 phospholipase D family, member 5 -2.17401
C9ORF85 chromosome 9 open reading frame 85 -2.16965
CTNND1 catenin (cadherin-associated protein), delta 1 -2.16715
C6ORF62 chromosome 6 open reading frame 62 -2.15693
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 -2.15487
PTGIS prostaglandin I2 (prostacyclin) synthase -2.09184
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q -2.0581
MRPS36 mitochondrial ribosomal protein S36 -2.04154
GLRX2 glutaredoxin 2 -2.03321
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -2.02754
SLC44A3 solute carrier family 44, member 3 -2.02754