FOXO3 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description forkhead box O3|This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2309)
External Link https://ncbi.nlm.nih.gov/gene/2309
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Genes

500 genes differentially expressed following the FOXO3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0208835
KLK11 kallikrein-related peptidase 11 0.0122952
DEFB1 defensin, beta 1 0.011903
KLK10 kallikrein-related peptidase 10 0.0105
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.0103256
KDM5D lysine (K)-specific demethylase 5D 0.0101884
KLK6 kallikrein-related peptidase 6 0.00970454
KLK8 kallikrein-related peptidase 8 0.00941639
MAL mal, T-cell differentiation protein 0.00922359
CCN2 cellular communication network factor 2 0.00890117
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.008769
IFI27 interferon, alpha-inducible protein 27 0.00862095
PDZK1IP1 PDZK1 interacting protein 1 0.00855997
TNNT1 troponin T type 1 (skeletal, slow) 0.00813432
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.00802071
HSPA1A heat shock 70kDa protein 1A 0.00795778
TMPRSS4 transmembrane protease, serine 4 0.00792226
LAMP5 lysosomal-associated membrane protein family, member 5 0.00789103
TMC5 transmembrane channel-like 5 0.00784937
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00783914
TUBB2A tubulin, beta 2A class IIa 0.00780175
ASS1 argininosuccinate synthase 1 0.00780104
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00772333
NVL nuclear VCP-like 0.0076643
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00758881
LGALS13 lectin, galactoside-binding, soluble, 13 0.00757942
ANOS1 anosmin 1 0.00755985
PUF60 poly-U binding splicing factor 60KDa 0.00747377
HIST1H2BD histone cluster 1, H2bd 0.00740372
TSPAN8 tetraspanin 8 0.00737276
KRT1 keratin 1, type II 0.00736492
EXPH5 exophilin 5 0.00731095
NNMT nicotinamide N-methyltransferase 0.0072899
C7 complement component 7 0.00714933
HIST1H2AC histone cluster 1, H2ac 0.00702103
RCAN1 regulator of calcineurin 1 0.00699666
CCP110 centriolar coiled coil protein 110kDa 0.00692685
KLK7 kallikrein-related peptidase 7 0.0069192
KCTD12 potassium channel tetramerization domain containing 12 0.00685656
ZNF185 zinc finger protein 185 (LIM domain) 0.00683593
LCN2 lipocalin 2 0.00670951
GPX1 glutathione peroxidase 1 0.00670378
SMCO4 single-pass membrane protein with coiled-coil domains 4 0.00669625
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00664401
FXYD2 FXYD domain containing ion transport regulator 2 0.00664167
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00664019
NMU neuromedin U 0.00656156
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.0065019
VNN1 vanin 1 0.00646008
GRB7 growth factor receptor-bound protein 7 0.00644079
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00631341
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00627922
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.00627508
WT1 Wilms tumor 1 0.00621519
IFI44 interferon-induced protein 44 0.00620671
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.00617332
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00615635
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00615032
LAMP3 lysosomal-associated membrane protein 3 0.00613018
TM9SF3 transmembrane 9 superfamily member 3 0.00598422
RNH1 ribonuclease/angiogenin inhibitor 1 0.00597205
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00596622
MIPEP mitochondrial intermediate peptidase 0.0058645
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.00582283
XK X-linked Kx blood group 0.00581551
EGR3 early growth response 3 0.00580234
XPO7 exportin 7 0.00577971
PALMD palmdelphin 0.00573906
GMDS GDP-mannose 4,6-dehydratase 0.00573237
ECI2 enoyl-CoA delta isomerase 2 0.00570036
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00568067
KLK5 kallikrein-related peptidase 5 0.00565547
KLK13 kallikrein-related peptidase 13 0.00562499
VDAC1 voltage-dependent anion channel 1 0.00561665
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.00561082
RHCG Rh family, C glycoprotein 0.00560419
JADE3 jade family PHD finger 3 0.00559939
MZB1 marginal zone B and B1 cell-specific protein 0.0055696
HIST1H2BK histone cluster 1, H2bk 0.00556218
NAV3 neuron navigator 3 0.00554836
FOLR1 folate receptor 1 (adult) 0.0055149
PODXL podocalyxin-like 0.00549677
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 0.00549568
OTULINL OTU deubiquitinase with linear linkage specificity like 0.00548607
KLF10 Kruppel-like factor 10 0.00546939
JPT1 Jupiter microtubule associated homolog 1 0.00546148
KRT2 keratin 2, type II 0.00544592
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00544277
BICC1 BicC family RNA binding protein 1 0.00543187
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) 0.00540319
RPIA ribose 5-phosphate isomerase A 0.005401
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.00540019
EVI2A ecotropic viral integration site 2A 0.00539927
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00539369
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.00537835
SLC44A4 solute carrier family 44, member 4 0.00537782
CYCS cytochrome c, somatic 0.00537257
RAB40B RAB40B, member RAS oncogene family 0.0053561
TMPO thymopoietin 0.00534746
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00534718
AQP9 aquaporin 9 0.00531719
GMPR guanosine monophosphate reductase 0.00530521
FMO1 flavin containing monooxygenase 1 0.00529814
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 0.00524461
UBE2S ubiquitin-conjugating enzyme E2S 0.00523439
SRPX sushi-repeat containing protein, X-linked 0.0052332
NOD2 nucleotide-binding oligomerization domain containing 2 0.00522333
CXCL2 chemokine (C-X-C motif) ligand 2 0.00520417
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.00520241
CD93 CD93 molecule 0.00519862
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00518408
IFITM2 interferon induced transmembrane protein 2 0.00515747
MSMB microseminoprotein, beta- 0.00514696
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.00512924
BIRC3 baculoviral IAP repeat containing 3 0.00512736
SLURP1 secreted LY6/PLAUR domain containing 1 0.00512629
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.00511905
KLK12 kallikrein-related peptidase 12 0.005119
TSPAN1 tetraspanin 1 0.00511137
TJP2 tight junction protein 2 0.00510734
YBX3 Y box binding protein 3 0.00510583
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.00510384
AQP3 aquaporin 3 (Gill blood group) 0.00509099
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.00509067
CLIC5 chloride intracellular channel 5 0.0050645
CA2 carbonic anhydrase II 0.00505559
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00504481
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00503855
CLDN10 claudin 10 0.00502164
MT2A metallothionein 2A 0.0050194
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.00501679
IL15 interleukin 15 0.0049666
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.0049529
DSG1 desmoglein 1 0.00495031
BCCIP BRCA2 and CDKN1A interacting protein 0.00494541
COL6A3 collagen, type VI, alpha 3 0.00494427
MB myoglobin 0.00490746
MRPL13 mitochondrial ribosomal protein L13 0.00490282
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00489238
OSBPL3 oxysterol binding protein-like 3 0.00489078
CAPG capping protein (actin filament), gelsolin-like 0.00487883
SPON1 spondin 1, extracellular matrix protein 0.00487485
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant 0.00487471
AOC1 amine oxidase, copper containing 1 0.00487429
FGFR1 fibroblast growth factor receptor 1 0.004864
S100A7 S100 calcium binding protein A7 0.00485803
S100A14 S100 calcium binding protein A14 0.00484769
CA12 carbonic anhydrase XII 0.00484742
IFI16 interferon, gamma-inducible protein 16 0.00484342
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 0.00484324
TYRP1 tyrosinase-related protein 1 0.0048336
LGALS3 lectin, galactoside-binding, soluble, 3 0.00483303
TPM2 tropomyosin 2 (beta) 0.00482564
RXYLT1 ribitol xylosyltransferase 1 0.00481835
ARHGAP29 Rho GTPase activating protein 29 0.00480236
C6 complement component 6 0.00478478
LY86 lymphocyte antigen 86 0.00478261
LAMA2 laminin, alpha 2 0.00477631
LMNB1 lamin B1 0.00477171
AATF apoptosis antagonizing transcription factor 0.00476668
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00474576
LOR loricrin 0.0047419
SKAP1 src kinase associated phosphoprotein 1 0.00472953
MRPS2 mitochondrial ribosomal protein S2 0.004715
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00471383
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 0.00471275
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 0.0047118
NAP1L1 nucleosome assembly protein 1-like 1 0.00468553
TXN thioredoxin 0.0046854
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.00468289
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.00467071
RIOK3 RIO kinase 3 0.0046647
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.00465607
CSRP2 cysteine and glycine-rich protein 2 0.00464716
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00464474
FAR2 fatty acyl CoA reductase 2 0.00464111
MSLN mesothelin 0.00462078
NANS N-acetylneuraminic acid synthase 0.00461175
TPPP3 tubulin polymerization-promoting protein family member 3 0.00460571
MX1 MX dynamin-like GTPase 1 0.00460199
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.00460054
KAT7 K(lysine) acetyltransferase 7 0.00459806
ZNF217 zinc finger protein 217 0.00458683
MAOB monoamine oxidase B 0.00458279
IL10RB interleukin 10 receptor, beta 0.00456764
ATP11B ATPase, class VI, type 11B 0.00456715
CUEDC2 CUE domain containing 2 0.00455885
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.0045572
PRPS2 phosphoribosyl pyrophosphate synthetase 2 0.004556
RELN reelin 0.0045479
AOX1 aldehyde oxidase 1 0.00454777
DUSP2 dual specificity phosphatase 2 0.00454313
HCLS1 hematopoietic cell-specific Lyn substrate 1 0.00453245
GLCE glucuronic acid epimerase 0.0045284
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00451767
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.00451164
PROM1 prominin 1 0.00450936
LY75 lymphocyte antigen 75 0.0044908
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.00448038
CALML5 calmodulin-like 5 0.00447674
SET SET nuclear proto-oncogene 0.00447657
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.00447407
ACOT7 acyl-CoA thioesterase 7 0.00446865
ARL4A ADP-ribosylation factor-like 4A 0.00446737
P3H2 prolyl 3-hydroxylase 2 0.00446331
HSDL2 hydroxysteroid dehydrogenase like 2 0.0044606
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00445888
RGS1 regulator of G-protein signaling 1 0.0044443
NKX2-1 NK2 homeobox 1 0.00443722
SASH3 SAM and SH3 domain containing 3 0.00443599
SOSTDC1 sclerostin domain containing 1 0.00443265
ATP10B ATPase, class V, type 10B 0.00443102
CYB561 cytochrome b561 0.00442575
CRELD2 cysteine-rich with EGF-like domains 2 0.00442414
SELL selectin L 0.00439133
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.00439047
IER2 immediate early response 2 0.00438617
PLCL1 phospholipase C-like 1 0.00436534
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 0.00435865
ADIRF adipogenesis regulatory factor 0.00435385
HSPA8 heat shock 70kDa protein 8 0.00435256
LIG1 ligase I, DNA, ATP-dependent 0.00435018
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 0.00434892
SELENOW selenoprotein W 0.00434764
AHNAK AHNAK nucleoprotein 0.00434433
HAL histidine ammonia-lyase 0.00433599
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 0.00433092
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.0043306
CH25H cholesterol 25-hydroxylase 0.00433024
FGFR4 fibroblast growth factor receptor 4 0.00428955
TMEM131L transmembrane 131 like 0.00428273
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00427074
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.0042695
KLF6 Kruppel-like factor 6 0.00424256
MT1E metallothionein 1E 0.00423527
EPS8L1 EPS8-like 1 0.00423006
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 0.00422379
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.0042192
LGALS1 lectin, galactoside-binding, soluble, 1 0.00421696
PCTP phosphatidylcholine transfer protein 0.00421528
RPA3 replication protein A3, 14kDa 0.00421333
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.00421276
CLDN8 claudin 8 0.00420548
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 0.00419602
CSTA cystatin A (stefin A) 0.00419112
PITX3 paired-like homeodomain 3 0.0041769
RRAS2 related RAS viral (r-ras) oncogene homolog 2 0.00417485
SRGN serglycin 0.00417247
MALL mal, T-cell differentiation protein-like 0.00417077
NEBL nebulette 0.00414374

decreased expression

Symbol Name Standardized Value
XIC X chromosome inactivation center -0.0191482
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0109732
BEX1 brain expressed, X-linked 1 -0.01012
CADM1 cell adhesion molecule 1 -0.00962382
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00955568
COL4A5 collagen, type IV, alpha 5 -0.00952356
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00925745
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00885412
PDE8B phosphodiesterase 8B -0.00852966
SDC3 syndecan 3 -0.00841444
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00835121
GNAS GNAS complex locus -0.00816176
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00815884
CCDC92 coiled-coil domain containing 92 -0.00775222
GOLGA8A golgin A8 family, member A -0.00771249
ACKR3 atypical chemokine receptor 3 -0.00742397
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -0.00722659
CLC Charcot-Leyden crystal galectin -0.00717911
ACTN1 actinin, alpha 1 -0.00695482
MGP matrix Gla protein -0.00689526
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00688477
TBX3 T-box 3 -0.00679808
DLX5 distal-less homeobox 5 -0.00676453
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00665333
SORBS2 sorbin and SH3 domain containing 2 -0.00665064
CCL2 chemokine (C-C motif) ligand 2 -0.00664978
MMP12 matrix metallopeptidase 12 -0.00662825
CPE carboxypeptidase E -0.00662079
NKX2-2 NK2 homeobox 2 -0.00657631
DYNLL1 dynein, light chain, LC8-type 1 -0.0065735
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.006489
OBSL1 obscurin-like 1 -0.00648324
HEBP2 heme binding protein 2 -0.00643722
TENT5A terminal nucleotidyltransferase 5A -0.00642678
STC2 stanniocalcin 2 -0.00637246
PRAME preferentially expressed antigen in melanoma -0.00632166
SDC2 syndecan 2 -0.00622266
MAP7 microtubule-associated protein 7 -0.00621863
EPHA4 EPH receptor A4 -0.00619684
GPNMB glycoprotein (transmembrane) nmb -0.00611259
NDFIP1 Nedd4 family interacting protein 1 -0.00606366
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.00597015
ITGA7 integrin, alpha 7 -0.0059316
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00589969
TNC tenascin C -0.00585906
COL15A1 collagen, type XV, alpha 1 -0.00583065
S100B S100 calcium binding protein B -0.00582562
RAB31 RAB31, member RAS oncogene family -0.0058077
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00577389
PHACTR2 phosphatase and actin regulator 2 -0.00576414
NPY1R neuropeptide Y receptor Y1 -0.00574435
AKR1C2 aldo-keto reductase family 1, member C2 -0.00572461
PDLIM7 PDZ and LIM domain 7 (enigma) -0.00562355
IRS1 insulin receptor substrate 1 -0.00561735
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -0.0056063
AKR1C1 aldo-keto reductase family 1, member C1 -0.00559324
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.00554564
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00554456
NMB neuromedin B -0.00552104
REG3A regenerating islet-derived 3 alpha -0.00551752
NIBAN1 niban apoptosis regulator 1 -0.00549487
IGFBP5 insulin-like growth factor binding protein 5 -0.00547803
GLUL glutamate-ammonia ligase -0.00547156
PBX1 pre-B-cell leukemia homeobox 1 -0.00544667
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00543711
G6PD glucose-6-phosphate dehydrogenase -0.00543432
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.00543175
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -0.00543077
TMEM106B transmembrane protein 106B -0.00541658
CCND2 cyclin D2 -0.00541487
TRIB2 tribbles pseudokinase 2 -0.00541053
MAOA monoamine oxidase A -0.00538097
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 -0.00537619
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00536981
SV2A synaptic vesicle glycoprotein 2A -0.0053591
FLNA filamin A, alpha -0.00534371
GSTM3 glutathione S-transferase mu 3 (brain) -0.00533756
TPD52L1 tumor protein D52-like 1 -0.0053248
PEBP1 phosphatidylethanolamine binding protein 1 -0.00529139
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -0.00527521
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) -0.00527201
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00525898
MFAP5 microfibrillar associated protein 5 -0.00525806
CALD1 caldesmon 1 -0.00523625
TRIM2 tripartite motif containing 2 -0.00522922
TGFBI transforming growth factor, beta-induced, 68kDa -0.00521269
IGSF1 immunoglobulin superfamily, member 1 -0.00520189
MFGE8 milk fat globule-EGF factor 8 protein -0.00519609
LUM lumican -0.00515951
DTNA dystrobrevin, alpha -0.00515045
SORBS1 sorbin and SH3 domain containing 1 -0.00514571
TSPAN4 tetraspanin 4 -0.00514229
AKR1C3 aldo-keto reductase family 1, member C3 -0.00511955
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00511722
FSTL3 follistatin-like 3 (secreted glycoprotein) -0.00511153
MINK1 misshapen-like kinase 1 -0.00511094
ZBTB38 zinc finger and BTB domain containing 38 -0.00510744
PLTP phospholipid transfer protein -0.00510548
OLFM4 olfactomedin 4 -0.00508403
CBX6 chromobox homolog 6 -0.00506829
NRIP1 nuclear receptor interacting protein 1 -0.00506754
PALLD palladin, cytoskeletal associated protein -0.00506707
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -0.00506687
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 -0.00505224
CIDEC cell death-inducing DFFA-like effector c -0.00504906
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00501307
RPS27L ribosomal protein S27-like -0.00500171
BRD4 bromodomain containing 4 -0.0049863
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00497475
GSN gelsolin -0.00496793
KYNU kynureninase -0.0049515
TXNDC9 thioredoxin domain containing 9 -0.00493819
KLF9 Kruppel-like factor 9 -0.00492823
FADS1 fatty acid desaturase 1 -0.00492038
EIF5B eukaryotic translation initiation factor 5B -0.00491646
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -0.0048975
GLA galactosidase, alpha -0.00489226
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 -0.00488883
JAKMIP2 janus kinase and microtubule interacting protein 2 -0.00488102
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -0.00485104
MAP1B microtubule-associated protein 1B -0.00483835
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 -0.00483368
CBS cystathionine-beta-synthase -0.0048242
BEX4 brain expressed, X-linked 4 -0.00481511
ZNF91 zinc finger protein 91 -0.00480608
PMP22 peripheral myelin protein 22 -0.00480498
LRP4 low density lipoprotein receptor-related protein 4 -0.00480472
SCARB2 scavenger receptor class B, member 2 -0.00479631
PERP PERP, TP53 apoptosis effector -0.00479188
MRPL57 mitochondrial ribosomal protein L57 -0.00478144
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00477709
DEFA5 defensin, alpha 5, Paneth cell-specific -0.00477545
ABAT 4-aminobutyrate aminotransferase -0.00476562
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00472697
NME4 NME/NM23 nucleoside diphosphate kinase 4 -0.00470944
UGDH UDP-glucose 6-dehydrogenase -0.00470074
DDR2 discoidin domain receptor tyrosine kinase 2 -0.00469255
MSX1 msh homeobox 1 -0.00466689
NFIC nuclear factor I/C (CCAAT-binding transcription factor) -0.0046625
C3ORF14 chromosome 3 open reading frame 14 -0.00465999
ASPH aspartate beta-hydroxylase -0.0046594
HDGFL3 HDGF like 3 -0.00465913
JAG1 jagged 1 -0.00465282
RGL2 ral guanine nucleotide dissociation stimulator-like 2 -0.00464709
TSPYL4 TSPY-like 4 -0.00464457
FHL1 four and a half LIM domains 1 -0.00463913
CNN1 calponin 1, basic, smooth muscle -0.00463872
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -0.00462178
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00460647
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.00459
PEG3 paternally expressed 3 -0.00458133
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 -0.00457044
REEP5 receptor accessory protein 5 -0.0045693
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.00451763
CCL8 chemokine (C-C motif) ligand 8 -0.00451491
FABP4 fatty acid binding protein 4, adipocyte -0.00450928
SCRG1 stimulator of chondrogenesis 1 -0.00449815
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.00449393
SEPP1 selenoprotein P, plasma, 1 -0.00449019
SCAND1 SCAN domain containing 1 -0.00447747
RNF24 ring finger protein 24 -0.00445614
AHDC1 AT hook, DNA binding motif, containing 1 -0.00444867
SYT11 synaptotagmin XI -0.00444209
MAGEF1 melanoma antigen family F1 -0.00443796
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -0.00442757
STARD13 StAR-related lipid transfer (START) domain containing 13 -0.00442518
TIMP4 TIMP metallopeptidase inhibitor 4 -0.00442455
DNM1L dynamin 1-like -0.00442294
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -0.00441589
BASP1 brain abundant, membrane attached signal protein 1 -0.00441235
FTH1 ferritin, heavy polypeptide 1 -0.00440732
FNDC3B fibronectin type III domain containing 3B -0.00439789
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00439285
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00438445
LRRN3 leucine rich repeat neuronal 3 -0.00437581
KRT81 keratin 81, type II -0.00437573
TCAF1 TRPM8 channel-associated factor 1 -0.004362
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00434922
APOA1 apolipoprotein A-I -0.00434623
SALL1 spalt-like transcription factor 1 -0.00433757
APOC3 apolipoprotein C-III -0.00433276
PLAT plasminogen activator, tissue -0.00432846
ENAH enabled homolog (Drosophila) -0.00432794
LMBRD1 LMBR1 domain containing 1 -0.0043236
S100A8 S100 calcium binding protein A8 -0.00431464
NDN necdin, melanoma antigen (MAGE) family member -0.00431374
ITGAV integrin, alpha V -0.00430965
ARMCX3 armadillo repeat containing, X-linked 3 -0.00430538
KRT17 keratin 17, type I -0.00429873
ZNF512B zinc finger protein 512B -0.00428341
MXRA5 matrix-remodelling associated 5 -0.00426814
CA8 carbonic anhydrase VIII -0.00426413
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00425117
MYO1B myosin IB -0.0042406
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00423895
NOVA1 neuro-oncological ventral antigen 1 -0.00423205
NTM neurotrimin -0.00422566
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.00422447
PCDH9 protocadherin 9 -0.00422098
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 -0.00421966
ESR1 estrogen receptor 1 -0.0042109
VSIG4 V-set and immunoglobulin domain containing 4 -0.00419763
THBS4 thrombospondin 4 -0.00419493
FASN fatty acid synthase -0.00418431
MAST4 microtubule associated serine/threonine kinase family member 4 -0.00418333
SERINC1 serine incorporator 1 -0.00417761
TRAF3IP2 TRAF3 interacting protein 2 -0.00417125
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.0041711
LYZ lysozyme -0.00416942
NCAM1 neural cell adhesion molecule 1 -0.00416687
PAX6 paired box 6 -0.00416337
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.00415657
PARP2 poly (ADP-ribose) polymerase 2 -0.00414833
CST3 cystatin C -0.00414695
MMP8 matrix metallopeptidase 8 -0.0041458
ZFHX3 zinc finger homeobox 3 -0.00414579
PIGG phosphatidylinositol glycan anchor biosynthesis, class G -0.0041422
KRT13 keratin 13, type I -0.00413955
TLE5 TLE family member 5, transcriptional modulator -0.00413871
DUOX2 dual oxidase 2 -0.00413828
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.00412826
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00412161
ITM2A integral membrane protein 2A -0.00411525
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00411386
FGL2 fibrinogen-like 2 -0.00411051
SLC22A17 solute carrier family 22, member 17 -0.00410605
ECE1 endothelin converting enzyme 1 -0.00409972
CAMK2B calcium/calmodulin-dependent protein kinase II beta -0.00407604
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 -0.00407238
NCKAP1 NCK-associated protein 1 -0.00407146
PHLDA3 pleckstrin homology-like domain, family A, member 3 -0.00406169
TAC1 tachykinin, precursor 1 -0.00405707
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.00405657
CCN3 cellular communication network factor 3 -0.00405296
SFRP1 secreted frizzled-related protein 1 -0.00404604
TG thyroglobulin -0.00404474
HDDC2 HD domain containing 2 -0.00404342
ANKRD10 ankyrin repeat domain 10 -0.00403882
SEC62 SEC62 homolog (S. cerevisiae) -0.00403226
RAB32 RAB32, member RAS oncogene family -0.00401841
KHNYN KH and NYN domain containing -0.00401825
NBPF10 neuroblastoma breakpoint family, member 10 -0.00401331
GRK5 G protein-coupled receptor kinase 5 -0.00398584
CLSTN2 calsyntenin 2 -0.00398473
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00397915
THPO thrombopoietin -0.00396855
GTF2H5 general transcription factor IIH, polypeptide 5 -0.00396843
CLIP3 CAP-GLY domain containing linker protein 3 -0.00396029
HHEX hematopoietically expressed homeobox -0.00395565
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00395503