FOXO4 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description forkhead box O4|This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010] (NCBI Entrez Gene Database, 4303)
External Link http://www.ncbi.nlm.nih.gov/gene/4303
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Genes

29 interacting proteins for FOXO4 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ATXN3 ataxin 3
CCND1 cyclin D1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CREBBP CREB binding protein
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
EP300 E1A binding protein p300
ESR1 estrogen receptor 1
FOXG1 forkhead box G1
IGFBP1 insulin-like growth factor binding protein 1
MAPK10 mitogen-activated protein kinase 10
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
NLK nemo-like kinase
NRF1 nuclear respiratory factor 1
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
RAN RAN, member RAS oncogene family
SIRT1 sirtuin 1
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
UBC ubiquitin C
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
XPO1 exportin 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta