FOXP1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description forkhead box P1|This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 27086)
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Genes

315 genes differentially expressed following the FOXP1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TBX20 T-box 20 2.90057
PCDHB7 protocadherin beta 7 2.90057
SSTR1 somatostatin receptor 1 2.90057
GLYAT glycine-N-acyltransferase 2.90057
UNC13C unc-13 homolog C (C. elegans) 2.90057
DRICH1 aspartate-rich 1 2.90057
TMEM191B transmembrane protein 191B 2.90057
GJB2 gap junction protein, beta 2, 26kDa 2.90057
BMP8B bone morphogenetic protein 8b 2.90057
ARSF arylsulfatase F 2.90057
ADRB2 adrenoceptor beta 2, surface 2.90057
PRELP proline/arginine-rich end leucine-rich repeat protein 2.90057
CD1C CD1c molecule 2.90057
NDRG1 N-myc downstream regulated 1 2.90057
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 2.90057
UPK3A uroplakin 3A 2.90057
TMEM225 transmembrane protein 225 2.90057
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 2.90057
FGF21 fibroblast growth factor 21 2.90057
PARP3 poly (ADP-ribose) polymerase family, member 3 2.90057
SLC26A1 solute carrier family 26 (anion exchanger), member 1 2.90057
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 2.90057
SLC39A8 solute carrier family 39 (zinc transporter), member 8 2.90057
FAM221B family with sequence similarity 221, member B 2.90057
CXCL2 chemokine (C-X-C motif) ligand 2 2.90057
CSNK2A3 casein kinase 2, alpha 3 polypeptide 2.90057
RNF39 ring finger protein 39 2.90057
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 2.90057
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 2.90057
STAP1 signal transducing adaptor family member 1 2.90057
CAMK1G calcium/calmodulin-dependent protein kinase IG 2.90057
PCDHGA12 protocadherin gamma subfamily A, 12 2.90057
KRTAP4-9 keratin associated protein 4-9 2.90057
DHRS9 dehydrogenase/reductase (SDR family) member 9 2.90057
ATOH8 atonal homolog 8 (Drosophila) 2.90057
BFSP2 beaded filament structural protein 2, phakinin 2.90057
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.90057
PCDH8 protocadherin 8 2.90057
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 2.90057
RPUSD3 RNA pseudouridylate synthase domain containing 3 2.90057
LCN15 lipocalin 15 2.90057
SPNS2 spinster homolog 2 (Drosophila) 2.90057
OR51L1 olfactory receptor, family 51, subfamily L, member 1 2.90057
DPPA3 developmental pluripotency associated 3 2.90057
COPZ2 coatomer protein complex, subunit zeta 2 2.90057
S100A1 S100 calcium binding protein A1 2.90057
TWIST1 twist family bHLH transcription factor 1 2.90057
LY6S-AS1 LY6S antisense RNA 1 2.90057
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 2.90057
XKRX XK, Kell blood group complex subunit-related, X-linked 2.90057
F5 coagulation factor V (proaccelerin, labile factor) 2.90057
SYT15 synaptotagmin XV 2.90057
MROH5 maestro heat-like repeat family member 5 2.90057
UBE2E1 ubiquitin-conjugating enzyme E2E 1 2.90057
PRG4 proteoglycan 4 2.90057
PCDHGC3 protocadherin gamma subfamily C, 3 2.90057
ASIC3 acid sensing (proton gated) ion channel 3 2.90057
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 2.90057
FAM220A family with sequence similarity 220, member A 2.90057
PKD2L1 polycystic kidney disease 2-like 1 2.90057
AGA-DT AGA divergent transcript 2.90057
H2BW2 H2B.W histone 2 2.90057
CCN5 cellular communication network factor 5 2.90057
LORICRIN loricrin cornified envelope precursor protein 2.90057
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 2.90057
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.90057
GPR33 G protein-coupled receptor 33 (gene/pseudogene) 2.90057
TCERG1L transcription elongation regulator 1-like 2.90057
KRT86 keratin 86, type II 2.90057
ASIC4 acid sensing (proton gated) ion channel family member 4 2.90057
TAS1R1 taste receptor, type 1, member 1 2.90057
ARHGAP15 Rho GTPase activating protein 15 2.90057
OVOL3 ovo-like zinc finger 3 2.90057
C1ORF162 chromosome 1 open reading frame 162 2.90057
MSGN1 mesogenin 1 2.90057
MSX2 msh homeobox 2 2.90057
CBLN3 cerebellin 3 precursor 2.90057
EDAR ectodysplasin A receptor 2.90057
TEX101 testis expressed 101 2.90057
ERAS ES cell expressed Ras 2.90057
FPR1 formyl peptide receptor 1 2.90057
NHLRC4 NHL repeat containing 4 2.90057
TLR4 toll-like receptor 4 2.90057
TFEC transcription factor EC 2.90057
ADIG adipogenin 2.90057
ALG10B ALG10B, alpha-1,2-glucosyltransferase 2.90057
BARX2 BARX homeobox 2 2.90057
CELA2A chymotrypsin-like elastase family, member 2A 2.90057
PIWIL1 piwi-like RNA-mediated gene silencing 1 2.90057
FAM186A family with sequence similarity 186, member A 2.90057
C1QTNF8 C1q and tumor necrosis factor related protein 8 2.90057
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 2.90057
MIP major intrinsic protein of lens fiber 2.90057
FAM153A family with sequence similarity 153, member A 2.90057
GPR119 G protein-coupled receptor 119 2.90057
ANKRD63 ankyrin repeat domain 63 2.90057
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 2.90057
EBLN1 endogenous Bornavirus-like nucleoprotein 1 2.90057
CTSO cathepsin O 2.90057
CNTF ciliary neurotrophic factor 2.90057
CA5A carbonic anhydrase VA, mitochondrial 2.90057
HBE1 hemoglobin, epsilon 1 2.90057
KRTAP5-11 keratin associated protein 5-11 2.90057
GFI1B growth factor independent 1B transcription repressor 2.90057
LRRC46 leucine rich repeat containing 46 2.90057
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 2.90057
EBF2 early B-cell factor 2 2.90057
NPIPB15 nuclear pore complex interacting protein family, member B15 2.90057
MORC1 MORC family CW-type zinc finger 1 2.90057
LRRC25 leucine rich repeat containing 25 2.90057
STAB1 stabilin 1 2.90057
NANOGNB NANOG neighbor homeobox 2.90057
LYZ lysozyme 2.90057
DLX3 distal-less homeobox 3 2.90057
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 2.90057
ISL1 ISL LIM homeobox 1 2.90057
HRCT1 histidine rich carboxyl terminus 1 2.90057
ITGB7 integrin, beta 7 2.90057
C2CD4B C2 calcium-dependent domain containing 4B 2.90057
DRD4 dopamine receptor D4 2.90057
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 2.90057
FIBIN fin bud initiation factor homolog (zebrafish) 2.90057
MAB21L2 mab-21-like 2 (C. elegans) 2.90057
SPINK9 serine peptidase inhibitor, Kazal type 9 2.90057
NPFFR1 neuropeptide FF receptor 1 2.90057
TRADD TNFRSF1A-associated via death domain 2.90057
ZC3H12D zinc finger CCCH-type containing 12D 2.90057
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 2.90057
CALHM3 calcium homeostasis modulator 3 2.90057
OLFML1 olfactomedin-like 1 2.90057
PLA2G4E phospholipase A2, group IVE 2.90057
PHOX2A paired-like homeobox 2a 2.90057
GOLGA8M golgin A8 family, member M 2.90057
SLCO1C1 solute carrier organic anion transporter family, member 1C1 2.90057
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 2.90057
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 2.90057
CCDC177 coiled-coil domain containing 177 2.90057
TGM4 transglutaminase 4 2.90057
PGPEP1L pyroglutamyl-peptidase I-like 2.90057
CLNK cytokine-dependent hematopoietic cell linker 2.90057
POPDC2 popeye domain containing 2 2.90057
LPO lactoperoxidase 2.90057
TRPM8 transient receptor potential cation channel, subfamily M, member 8 2.90057
DMRTB1 DMRT-like family B with proline-rich C-terminal, 1 2.90057
RAD9B RAD9 homolog B (S. pombe) 2.90057
IRX4 iroquois homeobox 4 2.90057
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 2.90057
CPN2 carboxypeptidase N, polypeptide 2 2.90057
ALOX5AP arachidonate 5-lipoxygenase-activating protein 2.90057
FAIM2 Fas apoptotic inhibitory molecule 2 2.90057
PRR15L proline rich 15-like 2.90057
TM4SF19 transmembrane 4 L six family member 19 2.90057
MT1M metallothionein 1M 2.90057
ADAM18 ADAM metallopeptidase domain 18 2.90057
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 2.90057
MAGEB17 melanoma antigen family B17 2.90057
CIB3 calcium and integrin binding family member 3 2.90057
PLA2G5 phospholipase A2, group V 2.90057
PPP1R27 protein phosphatase 1, regulatory subunit 27 2.90057
GRAPL GRB2-related adaptor protein-like 2.90057
ACSM4 acyl-CoA synthetase medium-chain family member 4 2.90057
ELMOD3 ELMO/CED-12 domain containing 3 2.87746
ANPEP alanyl (membrane) aminopeptidase 2.79288
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.79288
DHRS1 dehydrogenase/reductase (SDR family) member 1 2.67168
UBA6 ubiquitin-like modifier activating enzyme 6 2.62596
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains 2.62358
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 2.59821
COPB1 coatomer protein complex, subunit beta 1 2.59515
BUD31 BUD31 homolog (S. cerevisiae) 2.57731
CCDC192 coiled-coil domain containing 192 2.51381
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) 2.48929
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 2.43213
KIF18B kinesin family member 18B 2.4063
DNAH12 dynein, axonemal, heavy chain 12 2.37805
NR1I2 nuclear receptor subfamily 1, group I, member 2 2.37805
CCDC154 coiled-coil domain containing 154 2.35884
LRRIQ4 leucine-rich repeats and IQ motif containing 4 2.35318
AGXT2 alanine--glyoxylate aminotransferase 2 2.35318
GSTO1 glutathione S-transferase omega 1 2.31993
SH3GL1 SH3-domain GRB2-like 1 2.29746
DNAAF1 dynein, axonemal, assembly factor 1 2.29383
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 2.29383
TAFA4 TAFA chemokine like family member 4 2.26394
ENO3 enolase 3 (beta, muscle) 2.26394
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 2.26235
STK32A serine/threonine kinase 32A 2.2583
PDK1 pyruvate dehydrogenase kinase, isozyme 1 2.24364
TSN translin 2.226
FAM228B family with sequence similarity 228, member B 2.2254
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 2.22197
CFAP46 cilia and flagella associated protein 46 2.21502
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 2.21372
CLPTM1L CLPTM1-like 2.17884
RHOB ras homolog family member B 2.17884
SPMIP4 sperm microtubule inner protein 4 2.17884
DOCK2 dedicator of cytokinesis 2 2.16356
MME membrane metallo-endopeptidase 2.15802
TMEM87B transmembrane protein 87B 2.14833
DYNLT5 dynein light chain Tctex-type family member 5 2.1307
ACP2 acid phosphatase 2, lysosomal 2.12042
CNKSR3 CNKSR family member 3 2.11912
IWS1 IWS1 homolog (S. cerevisiae) 2.10423
SYTL2 synaptotagmin-like 2 2.1035
SYBU syntabulin (syntaxin-interacting) 2.05339
DENND5B DENN/MADD domain containing 5B 2.05188
GATAD2B GATA zinc finger domain containing 2B 2.05188
MRPS25 mitochondrial ribosomal protein S25 2.04779
SRSF6 serine/arginine-rich splicing factor 6 2.03361
TRAPPC9 trafficking protein particle complex 9 2.0264
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 2.01443

decreased expression

Symbol Name Standardized Value
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1 -2.90057
ZNF536 zinc finger protein 536 -2.90057
ROM1 retinal outer segment membrane protein 1 -2.90057
DAND5 DAN domain family member 5, BMP antagonist -2.90057
SUN3 Sad1 and UNC84 domain containing 3 -2.90057
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 -2.90057
ZMYND12 zinc finger, MYND-type containing 12 -2.90057
VSIG1 V-set and immunoglobulin domain containing 1 -2.90057
SEMG1 semenogelin I -2.90057
ANO1 anoctamin 1, calcium activated chloride channel -2.90057
TMEM86A transmembrane protein 86A -2.90057
ADAM20 ADAM metallopeptidase domain 20 -2.90057
CD48 CD48 molecule -2.90057
CRX cone-rod homeobox -2.90057
FGD3 FYVE, RhoGEF and PH domain containing 3 -2.90057
NCCRP1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) -2.90057
COL20A1 collagen, type XX, alpha 1 -2.90057
PTAFR platelet-activating factor receptor -2.90057
FXYD2 FXYD domain containing ion transport regulator 2 -2.90057
MEDAG mesenteric estrogen-dependent adipogenesis -2.90057
CD101 CD101 molecule -2.90057
ASCL5 achaete-scute family bHLH transcription factor 5 -2.90057
PLAT plasminogen activator, tissue -2.90057
PRM1 protamine 1 -2.90057
SCD5 stearoyl-CoA desaturase 5 -2.90057
VSTM1 V-set and transmembrane domain containing 1 -2.90057
HLA-DOB major histocompatibility complex, class II, DO beta -2.90057
RNF170 ring finger protein 170 -2.90057
RTL9 retrotransposon Gag like 9 -2.90057
PTH2R parathyroid hormone 2 receptor -2.90057
GOLGA8H golgin A8 family, member H -2.90057
GSDMA gasdermin A -2.90057
LDB3 LIM domain binding 3 -2.90057
PCDH19 protocadherin 19 -2.90057
LTB4R2 leukotriene B4 receptor 2 -2.90057
SHISA4 shisa family member 4 -2.90057
TSNAXIP1 translin-associated factor X interacting protein 1 -2.90057
INPP1 inositol polyphosphate-1-phosphatase -2.78189
FAM86B2 family with sequence similarity 86, member B2 -2.78189
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 -2.78189
BCL3 B-cell CLL/lymphoma 3 -2.78189
RGS19 regulator of G-protein signaling 19 -2.77107
OMG oligodendrocyte myelin glycoprotein -2.74544
C22ORF23 chromosome 22 open reading frame 23 -2.74226
KDM3A lysine (K)-specific demethylase 3A -2.69381
AGO2 argonaute RISC catalytic component 2 -2.61435
SYT9 synaptotagmin IX -2.61183
ZXDB zinc finger, X-linked, duplicated B -2.59821
PURA purine-rich element binding protein A -2.55262
TMEM258 transmembrane protein 258 -2.51381
ARL10 ADP-ribosylation factor-like 10 -2.44245
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 -2.43116
DRAM1 DNA-damage regulated autophagy modulator 1 -2.36788
BIVM basic, immunoglobulin-like variable motif containing -2.35956
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -2.35956
TNNI3K TNNI3 interacting kinase -2.35884
RPL21 ribosomal protein L21 -2.3387
PRKCD protein kinase C, delta -2.33706
PCLAF PCNA clamp associated factor -2.3367
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 -2.3367
COL6A1 collagen, type VI, alpha 1 -2.30557
TUBA1B tubulin, alpha 1b -2.30395
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -2.29383
FOXP1 forkhead box P1 -2.27634
LAMA1 laminin, alpha 1 -2.27566
ZBTB17 zinc finger and BTB domain containing 17 -2.27481
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -2.27481
USP21 ubiquitin specific peptidase 21 -2.2583
GREB1L growth regulation by estrogen in breast cancer-like -2.25751
CXCL17 chemokine (C-X-C motif) ligand 17 -2.25678
RAB9B RAB9B, member RAS oncogene family -2.25678
IRS4 insulin receptor substrate 4 -2.25678
OSBPL11 oxysterol binding protein-like 11 -2.25678
PTPN21 protein tyrosine phosphatase, non-receptor type 21 -2.23112
MSTO1 misato 1, mitochondrial distribution and morphology regulator -2.22197
ZBTB11 zinc finger and BTB domain containing 11 -2.22197
NCOA1 nuclear receptor coactivator 1 -2.21603
ATN1 atrophin 1 -2.21502
BIRC2 baculoviral IAP repeat containing 2 -2.21502
BAZ1B bromodomain adjacent to zinc finger domain, 1B -2.17884
ADO 2-aminoethanethiol (cysteamine) dioxygenase -2.15871
CFAP97 cilia and flagella associated protein 97 -2.15735
JMY junction mediating and regulatory protein, p53 cofactor -2.1307
TMEM109 transmembrane protein 109 -2.12888
FBXO44 F-box protein 44 -2.096
SPX spexin hormone -2.08825
RGPD6 RANBP2-like and GRIP domain containing 6 -2.08825
C1ORF50 chromosome 1 open reading frame 50 -2.04779
NTMT2 N-terminal Xaa-Pro-Lys N-methyltransferase 2 -2.04559
TEDC1 tubulin epsilon and delta complex 1 -2.04559
DNAI2 dynein, axonemal, intermediate chain 2 -2.04559
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like -2.04347
PAQR8 progestin and adipoQ receptor family member VIII -2.03846
PLIN2 perilipin 2 -2.0272
KIFC2 kinesin family member C2 -2.0264
PDE8A phosphodiesterase 8A -2.0264
MTCH1 mitochondrial carrier 1 -2.02548
MRPL46 mitochondrial ribosomal protein L46 -2.02458
KLHL32 kelch-like family member 32 -2.0154
MYOZ1 myozenin 1 -2.0154
NOMO2 NODAL modulator 2 -2.01443
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -2.01443
CLTA clathrin, light chain A -2.01443
CD24 CD24 molecule -2.006