| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | forkhead box P2|This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010] (NCBI Entrez Gene Database, 93986) |
| External Link | https://ncbi.nlm.nih.gov/gene/93986 |
| Similar Terms | |
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499 genes differentially expressed following the FOXP2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| OLFM4 | olfactomedin 4 | 0.0214783 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0158072 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0150327 |
| MSLN | mesothelin | 0.0139914 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0115769 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0102862 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.0100989 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00973984 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00971768 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00967474 |
| ADIRF | adipogenesis regulatory factor | 0.00965293 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00964495 |
| KRT13 | keratin 13, type I | 0.0095314 |
| S100A8 | S100 calcium binding protein A8 | 0.00952408 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 0.0095084 |
| S100A9 | S100 calcium binding protein A9 | 0.0093174 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 0.00917469 |
| TBC1D31 | TBC1 domain family, member 31 | 0.00917409 |
| KLK11 | kallikrein-related peptidase 11 | 0.00917297 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00900965 |
| FGG | fibrinogen gamma chain | 0.00880198 |
| KIF20A | kinesin family member 20A | 0.00871634 |
| LCN2 | lipocalin 2 | 0.0084561 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00842208 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00839591 |
| ACP3 | acid phosphatase 3 | 0.00835108 |
| MUC16 | mucin 16, cell surface associated | 0.00818061 |
| MAL | mal, T-cell differentiation protein | 0.00812599 |
| KRT15 | keratin 15, type I | 0.00795228 |
| NMU | neuromedin U | 0.00790345 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00789946 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00789169 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00779811 |
| REG1A | regenerating islet-derived 1 alpha | 0.0077972 |
| MAGEA3 | melanoma antigen family A3 | 0.00772572 |
| ODC1 | ornithine decarboxylase 1 | 0.0076891 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00749761 |
| PLCB4 | phospholipase C, beta 4 | 0.00749345 |
| TMSB15A | thymosin beta 15a | 0.00745727 |
| MUC4 | mucin 4, cell surface associated | 0.00741846 |
| KAZN | kazrin, periplakin interacting protein | 0.0073794 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0073366 |
| HAT1 | histone acetyltransferase 1 | 0.0073342 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00730074 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00724826 |
| MT1X | metallothionein 1X | 0.00724585 |
| CLGN | calmegin | 0.0072352 |
| SELENBP1 | selenium binding protein 1 | 0.00717235 |
| PENK | proenkephalin | 0.0071423 |
| LRRC17 | leucine rich repeat containing 17 | 0.0071004 |
| EPHB2 | EPH receptor B2 | 0.00706127 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00696935 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00694523 |
| ADD3 | adducin 3 (gamma) | 0.00689877 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.00685579 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00679146 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.00669068 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00664652 |
| GTF3A | general transcription factor IIIA | 0.00662265 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.00661235 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00658562 |
| H1-10 | H1.10 linker histone | 0.00656687 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.0065444 |
| TRIM29 | tripartite motif containing 29 | 0.00648797 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0064879 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0064696 |
| TSPAN4 | tetraspanin 4 | 0.00646431 |
| CDC45 | cell division cycle 45 | 0.00645823 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.006421 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.00641446 |
| AMD1 | adenosylmethionine decarboxylase 1 | 0.00637562 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.00636909 |
| HMGB1 | high mobility group box 1 | 0.00632746 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.00630521 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00628451 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00628447 |
| CYTL1 | cytokine-like 1 | 0.00626258 |
| ARG2 | arginase 2 | 0.00619851 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00618234 |
| DUOX2 | dual oxidase 2 | 0.0061747 |
| ACKR3 | atypical chemokine receptor 3 | 0.00617221 |
| ICAM2 | intercellular adhesion molecule 2 | 0.00613965 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00613919 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00611744 |
| MT1E | metallothionein 1E | 0.00610167 |
| CRNN | cornulin | 0.00609186 |
| REG3A | regenerating islet-derived 3 alpha | 0.00607549 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0060399 |
| SOX17 | SRY (sex determining region Y)-box 17 | 0.00599007 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.00596051 |
| MEIS1 | Meis homeobox 1 | 0.00592563 |
| HAUS7 | HAUS augmin-like complex, subunit 7 | 0.00591067 |
| FZD6 | frizzled class receptor 6 | 0.00589117 |
| PGD | phosphogluconate dehydrogenase | 0.00588287 |
| NXT1 | nuclear transport factor 2-like export factor 1 | 0.00587085 |
| MT1G | metallothionein 1G | 0.00586449 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.00586107 |
| NPY | neuropeptide Y | 0.00585029 |
| KLK10 | kallikrein-related peptidase 10 | 0.00584375 |
| NEK2 | NIMA-related kinase 2 | 0.00582518 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.00582208 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00581474 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.00581319 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00580938 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.00575605 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00574342 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.00573755 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00573426 |
| MNS1 | meiosis-specific nuclear structural 1 | 0.00571 |
| CRIP2 | cysteine-rich protein 2 | 0.00570265 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00568964 |
| MLF1 | myeloid leukemia factor 1 | 0.00564501 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00564346 |
| REG1B | regenerating islet-derived 1 beta | 0.00563688 |
| EXOSC8 | exosome component 8 | 0.00559962 |
| KLK3 | kallikrein-related peptidase 3 | 0.00559945 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00558874 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00558286 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.00552939 |
| FUS | FUS RNA binding protein | 0.00552557 |
| MECOM | MDS1 and EVI1 complex locus | 0.0054864 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.00548248 |
| PBK | PDZ binding kinase | 0.00547441 |
| ZNF217 | zinc finger protein 217 | 0.00546786 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | 0.00545133 |
| CHMP6 | charged multivesicular body protein 6 | 0.00544205 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | 0.0054381 |
| SRGN | serglycin | 0.00543533 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00542944 |
| KLK2 | kallikrein-related peptidase 2 | 0.00540469 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | 0.00540188 |
| FASN | fatty acid synthase | 0.00539938 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | 0.00538881 |
| DKC1 | dyskeratosis congenita 1, dyskerin | 0.0053591 |
| MT1F | metallothionein 1F | 0.00533828 |
| H2AFV | H2A histone family, member V | 0.00532889 |
| CFI | complement factor I | 0.00532297 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00531129 |
| SNCAIP | synuclein, alpha interacting protein | 0.00527551 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | 0.0052739 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00526983 |
| SPRR1B | small proline-rich protein 1B | 0.00526757 |
| DACH1 | dachshund family transcription factor 1 | 0.00526528 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.00525698 |
| CP | ceruloplasmin (ferroxidase) | 0.00525607 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.00521888 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 0.00520682 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.00518554 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.00518382 |
| LEPR | leptin receptor | 0.005172 |
| MME | membrane metallo-endopeptidase | 0.00516973 |
| NFIB | nuclear factor I/B | 0.00516034 |
| SMAD6 | SMAD family member 6 | 0.00515745 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00513743 |
| MTERF3 | mitochondrial transcription termination factor 3 | 0.00512872 |
| ESD | esterase D | 0.00512759 |
| FABP6 | fatty acid binding protein 6, ileal | 0.00512586 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00512289 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00510861 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00507955 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00507501 |
| RNF144A | ring finger protein 144A | 0.00507054 |
| CLDN5 | claudin 5 | 0.00506499 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.0050615 |
| MAGEA12 | melanoma antigen family A12 | 0.00505991 |
| KRT16 | keratin 16, type I | 0.00504443 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 | 0.00504364 |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) | 0.00503211 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00502567 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00501458 |
| MUC1 | mucin 1, cell surface associated | 0.00500878 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | 0.00500025 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.00499766 |
| ANGPTL2 | angiopoietin-like 2 | 0.00499039 |
| EMD | emerin | 0.00498858 |
| MAB21L2 | mab-21-like 2 (C. elegans) | 0.00498388 |
| TJP3 | tight junction protein 3 | 0.00498312 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.00496343 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00495082 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00494441 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.00493789 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.00493503 |
| TGM2 | transglutaminase 2 | 0.00493458 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.00492374 |
| TBL1X | transducin (beta)-like 1X-linked | 0.00490862 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00490745 |
| FABP1 | fatty acid binding protein 1, liver | 0.00490616 |
| MT1M | metallothionein 1M | 0.00490109 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.00490029 |
| PANK2 | pantothenate kinase 2 | 0.00489305 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00488369 |
| CLIC5 | chloride intracellular channel 5 | 0.00487881 |
| KPNA3 | karyopherin alpha 3 (importin alpha 4) | 0.00487618 |
| TRMT5 | tRNA methyltransferase 5 | 0.00487348 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00486438 |
| CBX7 | chromobox homolog 7 | 0.00486371 |
| NPR1 | natriuretic peptide receptor 1 | 0.00485139 |
| DPEP1 | dipeptidase 1 (renal) | 0.00485075 |
| POLD2 | polymerase (DNA directed), delta 2, accessory subunit | 0.0048503 |
| KIF15 | kinesin family member 15 | 0.00483933 |
| FOLH1B | folate hydrolase 1B | 0.00483682 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase | 0.00483263 |
| E2F2 | E2F transcription factor 2 | 0.00482693 |
| NNMT | nicotinamide N-methyltransferase | 0.0048174 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00480768 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | 0.00480527 |
| PCNA | proliferating cell nuclear antigen | 0.00480485 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00478926 |
| ZNF532 | zinc finger protein 532 | 0.00478529 |
| KIF23 | kinesin family member 23 | 0.00478107 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00475729 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.00475704 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00475367 |
| PITX1 | paired-like homeodomain 1 | 0.00474681 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.00473841 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0047336 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00473208 |
| MOK | MOK protein kinase | 0.00473006 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00472953 |
| RAD51AP1 | RAD51 associated protein 1 | 0.0047278 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | 0.00472737 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00471639 |
| TMEM231 | transmembrane protein 231 | 0.00471513 |
| FBXO5 | F-box protein 5 | 0.00471128 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 | 0.00471019 |
| APOB | apolipoprotein B | 0.00470534 |
| CD320 | CD320 molecule | 0.00470387 |
| DCHS1 | dachsous cadherin-related 1 | 0.00469711 |
| GNAS | GNAS complex locus | 0.00469613 |
| CHKB | choline kinase beta | 0.00466478 |
| KLK8 | kallikrein-related peptidase 8 | 0.00466242 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.00466191 |
| MDFIC | MyoD family inhibitor domain containing | 0.00466078 |
| EXO1 | exonuclease 1 | 0.00465365 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00465152 |
| UBL4A | ubiquitin-like 4A | 0.00463522 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00462782 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00461956 |
| MPZL2 | myelin protein zero-like 2 | 0.00461024 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00460819 |
| MEOX1 | mesenchyme homeobox 1 | 0.0045888 |
| TASP1 | taspase, threonine aspartase, 1 | 0.0045859 |
| SMAGP | small cell adhesion glycoprotein | 0.00458342 |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | 0.00458166 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.00457118 |
| SUCLA2 | succinate-CoA ligase, ADP-forming, beta subunit | 0.00456716 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | 0.0045663 |
| MSX1 | msh homeobox 1 | 0.00455387 |
| SPRR1A | small proline-rich protein 1A | 0.00454377 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.0138956 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.0125658 |
| CA2 | carbonic anhydrase II | -0.0123029 |
| STK10 | serine/threonine kinase 10 | -0.0120142 |
| PEG3 | paternally expressed 3 | -0.011411 |
| XIC | X chromosome inactivation center | -0.0110982 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.0109961 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0109548 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.010758 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0103869 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00986629 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00980337 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00963646 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00958354 |
| DUSP5 | dual specificity phosphatase 5 | -0.00946787 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00908903 |
| GATA6 | GATA binding protein 6 | -0.0087278 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00867109 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00854879 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00853136 |
| THBS2 | thrombospondin 2 | -0.0085186 |
| NRCAM | neuronal cell adhesion molecule | -0.0084021 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00830135 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.00828476 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.00821939 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.0081812 |
| RTN2 | reticulon 2 | -0.00809998 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -0.00808534 |
| ADM | adrenomedullin | -0.00794059 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00788879 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00782284 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00781894 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00781021 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00778351 |
| MAP7 | microtubule-associated protein 7 | -0.00775856 |
| CADM1 | cell adhesion molecule 1 | -0.00774527 |
| IFI44L | interferon-induced protein 44-like | -0.00761198 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.00758653 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00757803 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00752065 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00748864 |
| PDE4DIP | phosphodiesterase 4D interacting protein | -0.0074103 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00738197 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00734601 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00733397 |
| CTSC | cathepsin C | -0.00729273 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00723467 |
| CD164 | CD164 molecule, sialomucin | -0.00722903 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00721617 |
| STK26 | serine/threonine protein kinase 26 | -0.00720527 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00719889 |
| DSE | dermatan sulfate epimerase | -0.00715161 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00714603 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0070218 |
| BSG | basigin (Ok blood group) | -0.00699409 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00698584 |
| GRN | granulin | -0.00697176 |
| RUNX1 | runt-related transcription factor 1 | -0.00696419 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00694605 |
| NPTN | neuroplastin | -0.00688978 |
| IRAG2 | inositol 1,4,5-triphosphate receptor associated 2 | -0.0068682 |
| NDRG1 | N-myc downstream regulated 1 | -0.00683757 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | -0.00681719 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00675682 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00674492 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00674261 |
| HNMT | histamine N-methyltransferase | -0.00672236 |
| BLNK | B-cell linker | -0.00668911 |
| IRF8 | interferon regulatory factor 8 | -0.00668168 |
| GPR137B | G protein-coupled receptor 137B | -0.00668069 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00666555 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.00666376 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00665802 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00663449 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00661327 |
| DUSP2 | dual specificity phosphatase 2 | -0.00660638 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.00659092 |
| CPD | carboxypeptidase D | -0.00659039 |
| EGR2 | early growth response 2 | -0.00654449 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00654235 |
| TOX3 | TOX high mobility group box family member 3 | -0.00653559 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00652685 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 | -0.00649265 |
| GCH1 | GTP cyclohydrolase 1 | -0.00648533 |
| TCTA | T-cell leukemia translocation altered | -0.00643723 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.00642013 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.00639845 |
| REEP1 | receptor accessory protein 1 | -0.00639354 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.00636776 |
| SHTN1 | shootin 1 | -0.00635837 |
| CTSA | cathepsin A | -0.00634009 |
| FAM3C | family with sequence similarity 3, member C | -0.00631549 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00631202 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00628099 |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | -0.00627497 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00623794 |
| CD52 | CD52 molecule | -0.00622649 |
| NAV3 | neuron navigator 3 | -0.00620737 |
| TYMP | thymidine phosphorylase | -0.0061815 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.00617365 |
| APOD | apolipoprotein D | -0.00616873 |
| SNX10 | sorting nexin 10 | -0.00616868 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | -0.00613935 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.00613127 |
| SCARB2 | scavenger receptor class B, member 2 | -0.0061232 |
| EFHD1 | EF-hand domain family, member D1 | -0.00612036 |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) | -0.00609891 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.00609542 |
| OFD1 | oral-facial-digital syndrome 1 | -0.00608692 |
| GPC3 | glypican 3 | -0.00607335 |
| CD8A | CD8a molecule | -0.00607328 |
| IL1A | interleukin 1, alpha | -0.00602996 |
| CST7 | cystatin F (leukocystatin) | -0.0059563 |
| IFI35 | interferon-induced protein 35 | -0.00594842 |
| TTC39A | tetratricopeptide repeat domain 39A | -0.0059449 |
| TLR4 | toll-like receptor 4 | -0.00593526 |
| XAF1 | XIAP associated factor 1 | -0.00593482 |
| MIR22HG | MIR22 host gene | -0.0059197 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -0.00588545 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.00587073 |
| HAL | histidine ammonia-lyase | -0.00586679 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.00586361 |
| IGSF3 | immunoglobulin superfamily, member 3 | -0.00584665 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00583307 |
| RAB14 | RAB14, member RAS oncogene family | -0.00583224 |
| IRF9 | interferon regulatory factor 9 | -0.00580082 |
| KLF9 | Kruppel-like factor 9 | -0.00578693 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00578132 |
| LYST | lysosomal trafficking regulator | -0.00576358 |
| MX1 | MX dynamin-like GTPase 1 | -0.00574878 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00574782 |
| PLXNC1 | plexin C1 | -0.00573965 |
| FAM198B | family with sequence similarity 198, member B | -0.0057244 |
| KIAA0125 | KIAA0125 | -0.00572385 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00572027 |
| SERINC1 | serine incorporator 1 | -0.0056785 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.00566693 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00565276 |
| TPD52 | tumor protein D52 | -0.00564507 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00563348 |
| EVI2A | ecotropic viral integration site 2A | -0.00562428 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | -0.00561586 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.00561052 |
| PLPP2 | phospholipid phosphatase 2 | -0.00560362 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | -0.00560361 |
| LPXN | leupaxin | -0.00560015 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00559429 |
| CTSH | cathepsin H | -0.00558066 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.0055748 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00555913 |
| ANXA10 | annexin A10 | -0.00555637 |
| AIM2 | absent in melanoma 2 | -0.00555613 |
| DCN | decorin | -0.00555429 |
| ZNF91 | zinc finger protein 91 | -0.00555332 |
| MVP | major vault protein | -0.00555086 |
| RHOB | ras homolog family member B | -0.00553875 |
| CHGB | chromogranin B | -0.00553814 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 | -0.00553676 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.0055289 |
| RAI14 | retinoic acid induced 14 | -0.00552705 |
| GOLGA8A | golgin A8 family, member A | -0.00551421 |
| PON3 | paraoxonase 3 | -0.00551137 |
| CST3 | cystatin C | -0.0055005 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.00549903 |
| ZNF589 | zinc finger protein 589 | -0.00549225 |
| RAB8B | RAB8B, member RAS oncogene family | -0.00548821 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.00548151 |
| CTSZ | cathepsin Z | -0.00547924 |
| TXNIP | thioredoxin interacting protein | -0.00547326 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00547283 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -0.00544711 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.00544297 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | -0.00543758 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | -0.00541376 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00540501 |
| RBM34 | RNA binding motif protein 34 | -0.00539836 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00538084 |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | -0.00537223 |
| DIPK1A | divergent protein kinase domain 1A | -0.00536509 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | -0.00536003 |
| RAB9A | RAB9A, member RAS oncogene family | -0.00535936 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00535699 |
| SLAMF7 | SLAM family member 7 | -0.00535523 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00534813 |
| CHI3L2 | chitinase 3-like 2 | -0.00533945 |
| CERS6 | ceramide synthase 6 | -0.0053096 |
| MFAP3L | microfibrillar-associated protein 3-like | -0.00530385 |
| VLDLR | very low density lipoprotein receptor | -0.0052971 |
| TPM4 | tropomyosin 4 | -0.00528473 |
| DST | dystonin | -0.00528393 |
| PTHLH | parathyroid hormone-like hormone | -0.00524575 |
| GUCY2C | guanylate cyclase 2C | -0.00524133 |
| HOXA5 | homeobox A5 | -0.00522189 |
| TRIM22 | tripartite motif containing 22 | -0.00521943 |
| MCL1 | myeloid cell leukemia 1 | -0.00521734 |
| RORA | RAR-related orphan receptor A | -0.00521528 |
| ANKRD12 | ankyrin repeat domain 12 | -0.00521435 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | -0.00521319 |
| BBX | bobby sox homolog (Drosophila) | -0.00521155 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | -0.0052017 |
| POPDC3 | popeye domain containing 3 | -0.00520119 |
| IL6 | interleukin 6 | -0.00519734 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.00518451 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.00517436 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00516501 |
| CHMP5 | charged multivesicular body protein 5 | -0.00516157 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.00516148 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.00515939 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | -0.00515889 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | -0.00515471 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.00513796 |
| FLT3 | fms-related tyrosine kinase 3 | -0.00513744 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.0051362 |
| MYRF | myelin regulatory factor | -0.00511902 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00511514 |
| FMO5 | flavin containing monooxygenase 5 | -0.00510367 |
| C3ORF52 | chromosome 3 open reading frame 52 | -0.00509241 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | -0.00507379 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0050593 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.00505746 |
| GSK3B | glycogen synthase kinase 3 beta | -0.00505678 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00505228 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.00504426 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00504357 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00504209 |
| STX7 | syntaxin 7 | -0.005037 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.00503695 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00503111 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00502741 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00501121 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00501104 |
| NPC1 | Niemann-Pick disease, type C1 | -0.00500827 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -0.0050067 |
| DCLK1 | doublecortin-like kinase 1 | -0.00498581 |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | -0.00498351 |
| STX3 | syntaxin 3 | -0.00497602 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00497441 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | -0.00496569 |
| EMX2 | empty spiracles homeobox 2 | -0.00496568 |
| CD84 | CD84 molecule | -0.00495071 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | -0.00492973 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00492961 |
| TMEM45A | transmembrane protein 45A | -0.00492171 |
| FLNB | filamin B, beta | -0.00492077 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | -0.0049013 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00490116 |
| WDR1 | WD repeat domain 1 | -0.00488353 |
| ABHD4 | abhydrolase domain containing 4 | -0.00488323 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.004877 |
| CA12 | carbonic anhydrase XII | -0.00487573 |
