FPGS Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description folylpolyglutamate synthase|This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. Alternative splicing results in transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014] (NCBI Entrez Gene Database, 2356)
External Link http://www.ncbi.nlm.nih.gov/gene/2356
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Genes

3 interacting proteins for FPGS from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
MAX MYC associated factor X
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
UBC ubiquitin C