FREM2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description FRAS1 related extracellular matrix protein 2|This gene encodes an integral membrane protein containing numerous CSPG (chondroitin sulfate proteoglycan element) repeats and Calx-beta domains. The encoded protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions. This protein is important for the integrity of skin and renal epithelia. Mutations in this gene are associated with Fraser syndrome. [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 341640)
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Genes

391 genes differentially expressed following the FREM2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 3.45262
COL20A1 collagen, type XX, alpha 1 3.45262
CD5 CD5 molecule 3.45262
LY86 lymphocyte antigen 86 3.45262
TSHB thyroid stimulating hormone, beta 3.45262
CEMP1 cementum protein 1 3.45262
CARD16 caspase recruitment domain family, member 16 3.45262
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 3.45262
WDR87 WD repeat domain 87 3.45262
VWA5B2 von Willebrand factor A domain containing 5B2 3.45262
A4GALT alpha 1,4-galactosyltransferase 3.45262
KNG1 kininogen 1 3.45262
KLRK1 killer cell lectin-like receptor subfamily K, member 1 3.45262
UPK3B uroplakin 3B 3.45262
HLX H2.0-like homeobox 3.45262
CFHR4 complement factor H-related 4 3.45262
PRB2 proline-rich protein BstNI subfamily 2 3.45262
LIPJ lipase, family member J 3.45262
LIPK lipase, family member K 3.45262
KLK1 kallikrein 1 3.45262
TAS2R39 taste receptor, type 2, member 39 3.45262
FRMD7 FERM domain containing 7 3.45262
FPR1 formyl peptide receptor 1 3.45262
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 3.45262
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 3.45262
MAP3K6 mitogen-activated protein kinase kinase kinase 6 3.45262
OVGP1 oviductal glycoprotein 1, 120kDa 3.45262
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 3.45262
TMEM176B transmembrane protein 176B 3.45262
HGD homogentisate 1,2-dioxygenase 3.45262
MOGAT3 monoacylglycerol O-acyltransferase 3 3.45262
CD68 CD68 molecule 3.45262
CRH corticotropin releasing hormone 3.45262
DLL4 delta-like 4 (Drosophila) 3.45262
MUC22 mucin 22 3.45262
TREML2 triggering receptor expressed on myeloid cells-like 2 3.45262
IL2RA interleukin 2 receptor, alpha 3.45262
DIO1 deiodinase, iodothyronine, type I 3.45262
SPHK1 sphingosine kinase 1 3.45262
HMX1 H6 family homeobox 1 3.45262
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 3.45262
SPAG6 sperm associated antigen 6 3.45262
RGPD3 RANBP2-like and GRIP domain containing 3 3.45262
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 3.45262
ADAMTSL5 ADAMTS-like 5 3.45262
OR2B6 olfactory receptor, family 2, subfamily B, member 6 3.45262
SLC25A45 solute carrier family 25, member 45 3.45262
NPSR1 neuropeptide S receptor 1 3.45262
MEI1 meiosis inhibitor 1 3.45262
MSC musculin 3.45262
OLFM4 olfactomedin 4 3.45262
TUBB1 tubulin, beta 1 class VI 3.45262
MFAP5 microfibrillar associated protein 5 3.45262
GPR22 G protein-coupled receptor 22 3.45262
ALPK2 alpha-kinase 2 3.45262
REN renin 3.45262
C11ORF87 chromosome 11 open reading frame 87 3.45262
UPP2 uridine phosphorylase 2 3.45262
FAM90A12 family with sequence similarity 90 member A12 3.45262
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 3.45262
MGAM maltase-glucoamylase 3.45262
ACER1 alkaline ceramidase 1 3.45262
DNAAF1 dynein, axonemal, assembly factor 1 3.45262
KRT86 keratin 86, type II 3.45262
FIMP1 fertilization-influencing membrane protein 1 3.45262
PLCZ1 phospholipase C, zeta 1 3.45262
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 3.45262
LMNTD1 lamin tail domain containing 1 3.45262
TMPRSS7 transmembrane protease, serine 7 3.45262
PROX2 prospero homeobox 2 3.45262
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 3.45262
ALX4 ALX homeobox 4 3.45262
OR10H1 olfactory receptor, family 10, subfamily H, member 1 3.45262
PTH1R parathyroid hormone 1 receptor 3.45262
ACKR5 atypical chemokine receptor 5 3.45262
LITAFD LITAF domain containing 3.45262
LRRC8C-DT LRRC8C divergent transcript 3.45262
C17ORF113 chromosome 17 open reading frame 113 3.45262
LOC124903372 uncharacterized LOC124903372 3.45262
GREP1 glycine rich extracellular protein 1 3.45262
DYNLT4 dynein light chain Tctex-type 4 3.45262
KASH5 KASH domain containing 5 3.45262
ATOSB atos homolog B 3.45262
CCN3 cellular communication network factor 3 3.45262
CFAP65 cilia and flagella associated protein 65 3.45262
NIBAN3 niban apoptosis regulator 3 3.45262
TRIM31 tripartite motif containing 31 3.45262
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 3.45262
CELA2A chymotrypsin-like elastase family, member 2A 3.45262
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) 3.45262
MIA melanoma inhibitory activity 3.45262
MYH15 myosin, heavy chain 15 3.45262
ADGRG1 adhesion G protein-coupled receptor G1 3.45262
S1PR1 sphingosine-1-phosphate receptor 1 3.45262
CXCL16 chemokine (C-X-C motif) ligand 16 3.45262
LOC124909439 uncharacterized LOC124909439 3.45262
AXDND1 axonemal dynein light chain domain containing 1 3.45262
CLIP4 CAP-GLY domain containing linker protein family, member 4 3.45262
DAO D-amino-acid oxidase 3.45262
VSX2 visual system homeobox 2 3.45262
RGS22 regulator of G-protein signaling 22 3.45262
PGA5 pepsinogen 5, group I (pepsinogen A) 3.45262
LGSN lengsin, lens protein with glutamine synthetase domain 3.45262
PIRT phosphoinositide-interacting regulator of transient receptor potential channels 3.45262
DOK7 docking protein 7 3.45262
ZNF441 zinc finger protein 441 3.45262
REP15 RAB15 effector protein 3.45262
ZNF705G zinc finger protein 705G 3.45262
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like 3.45262
F5 coagulation factor V (proaccelerin, labile factor) 3.45262
GATA2 GATA binding protein 2 3.45262
LRRN4CL LRRN4 C-terminal like 3.45262
PRG3 proteoglycan 3 3.45262
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 3.45262
ASIC4 acid sensing (proton gated) ion channel family member 4 3.45262
DEFB1 defensin, beta 1 3.45262
CALML5 calmodulin-like 5 3.45262
IL21R interleukin 21 receptor 3.45262
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 3.45262
CLEC4G C-type lectin domain family 4, member G 3.45262
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 3.45262
RSPH10B radial spoke head 10 homolog B (Chlamydomonas) 3.45262
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 3.45262
PCDHGA2 protocadherin gamma subfamily A, 2 3.45262
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 3.45262
TEX12 testis expressed 12 3.45262
DMRTA2 DMRT-like family A2 3.45262
BEAN1 brain expressed, associated with NEDD4, 1 3.45262
DPRX divergent-paired related homeobox 3.45262
RETNLB resistin like beta 3.45262
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene) 3.45262
ACVR2B activin A receptor, type IIB 3.45262
GNG8 guanine nucleotide binding protein (G protein), gamma 8 3.45262
PHOSPHO1 phosphatase, orphan 1 3.45262
NPPA natriuretic peptide A 3.45262
CH25H cholesterol 25-hydroxylase 3.45262
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 3.45262
CERKL ceramide kinase-like 3.45262
AQP4 aquaporin 4 3.45262
AQP6 aquaporin 6, kidney specific 3.45262
MUC17 mucin 17, cell surface associated 3.45262
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 3.45262
IL9R interleukin 9 receptor 3.45262
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 3.45262
HLA-DMB major histocompatibility complex, class II, DM beta 3.45262
SP140L SP140 nuclear body protein-like 3.45262
ADAM18 ADAM metallopeptidase domain 18 3.45262
GBX1 gastrulation brain homeobox 1 3.45262
CCDC78 coiled-coil domain containing 78 3.45262
DRC1 dynein regulatory complex subunit 1 3.45262
SYT4 synaptotagmin IV 3.45262
ZNF831 zinc finger protein 831 3.45262
GJC2 gap junction protein, gamma 2, 47kDa 3.45262
GOLGA8K golgin A8 family, member K 3.45262
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 3.45262
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 3.45262
ARL13A ADP-ribosylation factor-like 13A 3.45262
CRYBA1 crystallin, beta A1 3.45262
PRSS37 protease, serine, 37 3.45262
PRH2 proline-rich protein HaeIII subfamily 2 3.45262
INSM1 insulinoma-associated 1 3.45262
PRTN3 proteinase 3 3.45262
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 3.45262
ATP10B ATPase, class V, type 10B 3.45262
SH2D1A SH2 domain containing 1A 3.45262
PHGR1 proline/histidine/glycine-rich 1 3.45262
IGIP IgA-inducing protein 3.45262
BRDT bromodomain, testis-specific 3.45262
ANKRD31 ankyrin repeat domain 31 3.45262
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 3.45262
NUTM2A NUT family member 2A 3.45262
OR14A16 olfactory receptor, family 14, subfamily A, member 16 3.45262
NLRP4 NLR family, pyrin domain containing 4 3.45262
LHX6 LIM homeobox 6 3.45262
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 3.45262
SLC7A4 solute carrier family 7, member 4 3.45262
NEUROD2 neuronal differentiation 2 3.45262
IRX4 iroquois homeobox 4 3.45262
CD226 CD226 molecule 3.45262
PXT1 peroxisomal, testis specific 1 3.45262
CLNK cytokine-dependent hematopoietic cell linker 3.45262
GPRC5D G protein-coupled receptor, class C, group 5, member D 3.45262
ARGFX arginine-fifty homeobox 3.45262
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 3.45262
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 3.45262
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 3.45262
NUTM2G NUT family member 2G 3.45262
GREM2 gremlin 2, DAN family BMP antagonist 3.45262
BIN2 bridging integrator 2 3.45262
SMCO3 single-pass membrane protein with coiled-coil domains 3 3.45262
UPK2 uroplakin 2 3.45008
DRC3 dynein regulatory complex subunit 3 3.40751
TUBA4B tubulin, alpha 4b 3.40751
ASTE1 asteroid homolog 1 (Drosophila) 3.09913
QRICH1 glutamine-rich 1 3.06133
GYS2 glycogen synthase 2 (liver) 3.03107
MROH1 maestro heat-like repeat family member 1 2.98018
MOV10 Mov10 RISC complex RNA helicase 2.93575
MUC4 mucin 4, cell surface associated 2.90349
RANBP17 RAN binding protein 17 2.9026
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 2.88995
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit 2.88222
HSPG2 heparan sulfate proteoglycan 2 2.88222
STARD7 StAR-related lipid transfer (START) domain containing 7 2.85137
BRD4 bromodomain containing 4 2.71761
NAF1 nuclear assembly factor 1 ribonucleoprotein 2.65864
LRRC3B leucine rich repeat containing 3B 2.56381
SNIP1 Smad nuclear interacting protein 1 2.56381
ZNF878 zinc finger protein 878 2.55044
TRAF2 TNF receptor-associated factor 2 2.53485
EMC10 ER membrane protein complex subunit 10 2.51419
CCNC cyclin C 2.48136
ARSL arylsulfatase L 2.47818
MSANTD7 Myb/SANT DNA binding domain containing 7 2.45617
ALMS1 Alstrom syndrome protein 1 2.45141
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 2.39529
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 2.39168
SOX13 SRY (sex determining region Y)-box 13 2.39097
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 2.38541
ECI1 enoyl-CoA delta isomerase 1 2.38233
GLRB glycine receptor, beta 2.3795
H3-7 H3.7 histone (putative) 2.3795
NPIPA6 nuclear pore complex interacting protein family, member A6 2.3795
IGSF23 immunoglobulin superfamily, member 23 2.3795
EPHA3 EPH receptor A3 2.3795
SPESP1 sperm equatorial segment protein 1 2.3795
CXCL17 chemokine (C-X-C motif) ligand 17 2.3795
MSR1 macrophage scavenger receptor 1 2.3795
TET2 tet methylcytosine dioxygenase 2 2.36589
RNF25 ring finger protein 25 2.36518
FBXL14 F-box and leucine-rich repeat protein 14 2.35953
KTN1 kinectin 1 (kinesin receptor) 2.30414
LRFN5 leucine rich repeat and fibronectin type III domain containing 5 2.30382
CCDC6 coiled-coil domain containing 6 2.29961
BLVRB biliverdin reductase B 2.2964
RAB11B RAB11B, member RAS oncogene family 2.26799
LEFTY1 left-right determination factor 1 2.26368
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 2.25826
RBPJ recombination signal binding protein for immunoglobulin kappa J region 2.2341
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 2.22047
IGBP1 immunoglobulin (CD79A) binding protein 1 2.21557
STIP1 stress-induced phosphoprotein 1 2.19831
CCKBR cholecystokinin B receptor 2.1863
TMEM51 transmembrane protein 51 2.17729
NXT1 nuclear transport factor 2-like export factor 1 2.16197
CRABP2 cellular retinoic acid binding protein 2 2.15119
MT1X metallothionein 1X 2.11107
GIGYF2 GRB10 interacting GYF protein 2 2.10764
EED embryonic ectoderm development 2.10327
RPH3A rabphilin 3A 2.10327
SMAD1 SMAD family member 1 2.08604
ZNF207 zinc finger protein 207 2.08135
NKAP NFKB activating protein 2.07048
FBXO31 F-box protein 31 2.07048
TMEM69 transmembrane protein 69 2.07048
TRIML2 tripartite motif family-like 2 2.06921
FNBP1L formin binding protein 1-like 2.06286
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 2.06037
GSDMD gasdermin D 2.0562
CLIC4 chloride intracellular channel 4 2.05568
HADH hydroxyacyl-CoA dehydrogenase 2.04304
SLC19A1 solute carrier family 19 (folate transporter), member 1 2.04304
EPHB2 EPH receptor B2 2.03785
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 2.03394
EML1 echinoderm microtubule associated protein like 1 2.01828
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta 2.01082
KIAA0753 KIAA0753 2.00189
C1ORF94 chromosome 1 open reading frame 94 2.00189

decreased expression

Symbol Name Standardized Value
IGSF22 immunoglobulin superfamily, member 22 -3.45262
FAM181B family with sequence similarity 181, member B -3.45262
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 -3.45262
CATSPER4 cation channel, sperm associated 4 -3.45262
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -3.45262
TRAF3IP3 TRAF3 interacting protein 3 -3.45262
KCTD4 potassium channel tetramerization domain containing 4 -3.45262
DISP2 dispatched homolog 2 (Drosophila) -3.45262
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 -3.45262
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 -3.45262
FRS3 fibroblast growth factor receptor substrate 3 -3.45262
ZNF471 zinc finger protein 471 -3.45262
ELFN1 extracellular leucine-rich repeat and fibronectin type III domain containing 1 -3.45262
MCHR1 melanin-concentrating hormone receptor 1 -3.45262
ALX1 ALX homeobox 1 -3.45262
CCDC92 coiled-coil domain containing 92 -3.45262
C7orf78 chromosome 7 open reading frame 78 -3.45262
REC114 REC114 meiotic recombination protein -3.45262
DUSP10 dual specificity phosphatase 10 -3.45262
MTMR11 myotubularin related protein 11 -3.45262
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase -3.45262
F7 coagulation factor VII (serum prothrombin conversion accelerator) -3.45262
NHLH1 nescient helix loop helix 1 -3.45262
CR2 complement component (3d/Epstein Barr virus) receptor 2 -3.45262
COL15A1 collagen, type XV, alpha 1 -3.45262
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -3.45262
VCX variable charge, X-linked -3.45262
PDCL2 phosducin-like 2 -3.45262
G0S2 G0/G1 switch 2 -3.45262
DAPL1 death associated protein-like 1 -3.45262
SDR42E2 short chain dehydrogenase/reductase family 42E, member 2 -3.45262
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 -3.45262
CTXND1 cortexin domain containing 1 -3.45262
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B -3.45262
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 -3.45262
PLD6 phospholipase D family, member 6 -3.45262
SMIM17 small integral membrane protein 17 -3.45262
PCDHA11 protocadherin alpha 11 -3.45262
NDNF neuron-derived neurotrophic factor -3.45262
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -3.45262
HDAC10 histone deacetylase 10 -3.45262
DCLK3 doublecortin-like kinase 3 -3.45262
PHOX2A paired-like homeobox 2a -3.45262
HPD 4-hydroxyphenylpyruvate dioxygenase -3.45262
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -3.45262
DNAAF19 dynein axonemal assembly factor 19 -3.45262
DCT dopachrome tautomerase -3.45262
PDE3A phosphodiesterase 3A, cGMP-inhibited -3.29425
APCDD1 adenomatosis polyposis coli down-regulated 1 -3.29377
EIF4E eukaryotic translation initiation factor 4E -3.25581
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta -3.15108
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 -3.01492
MTPAP mitochondrial poly(A) polymerase -2.99337
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide -2.85137
CCDC142 coiled-coil domain containing 142 -2.82645
SPATA24 spermatogenesis associated 24 -2.80719
FANCF Fanconi anemia, complementation group F -2.78689
ZNF615 zinc finger protein 615 -2.75564
CA13 carbonic anhydrase XIII -2.75564
KIAA0040 KIAA0040 -2.75477
PCYT1A phosphate cytidylyltransferase 1, choline, alpha -2.7477
TCF7 transcription factor 7 (T-cell specific, HMG-box) -2.70805
MAPRE3 microtubule-associated protein, RP/EB family, member 3 -2.62021
VEGFB vascular endothelial growth factor B -2.57398
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.57378
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 -2.55378
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -2.54953
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.47818
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 -2.45614
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) -2.39858
FAR2 fatty acyl CoA reductase 2 -2.39605
WIPI1 WD repeat domain, phosphoinositide interacting 1 -2.3903
CEP112 centrosomal protein 112kDa -2.38541
TBX19 T-box 19 -2.3795
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase -2.37653
KNOP1 lysine-rich nucleolar protein 1 -2.36376
FAM177A1 family with sequence similarity 177, member A1 -2.35823
MRPL55 mitochondrial ribosomal protein L55 -2.33462
SETD9 SET domain containing 9 -2.3252
IL23A interleukin 23, alpha subunit p19 -2.32462
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1 -2.32462
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) -2.32462
DOC2B double C2-like domains, beta -2.32462
GID8 GID complex subunit 8 -2.29961
AGER advanced glycosylation end product-specific receptor -2.2964
SBK2 SH3 domain binding kinase family, member 2 -2.2964
HSPA12B heat shock 70kD protein 12B -2.2964
RGN regucalcin -2.2964
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -2.28633
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -2.27634
ANGPTL4 angiopoietin-like 4 -2.27634
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 -2.27634
H4C1 H4 clustered histone 1 -2.27634
MPRIP myosin phosphatase Rho interacting protein -2.27458
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.27215
USP10 ubiquitin specific peptidase 10 -2.27016
POFUT3 protein O-fucosyltransferase 3 -2.26799
SASH1 SAM and SH3 domain containing 1 -2.26799
EP400 E1A binding protein p400 -2.24118
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -2.22275
HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 -2.22047
SPRED3 sprouty-related, EVH1 domain containing 3 -2.21004
DGLUCY D-glutamate cyclase -2.19831
PIPOX pipecolic acid oxidase -2.16981
ZNF322 zinc finger protein 322 -2.16172
BORCS7 BLOC-1 related complex subunit 7 -2.14123
FREM2 FRAS1 related extracellular matrix protein 2 -2.14123
MTERF2 mitochondrial transcription termination factor 2 -2.13027
RFTN1 raftlin, lipid raft linker 1 -2.12956
UBA3 ubiquitin-like modifier activating enzyme 3 -2.11745
GSN gelsolin -2.11071
CNOT9 CCR4-NOT transcription complex subunit 9 -2.08618
CSNK2A1 casein kinase 2, alpha 1 polypeptide -2.07549
RPL23A ribosomal protein L23a -2.07462
FAM234B family with sequence similarity 234 member B -2.07048
ZNF677 zinc finger protein 677 -2.0562
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 -2.04315
INMT indolethylamine N-methyltransferase -2.04304
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.03869
SETD3 SET domain containing 3 -2.0337
CLCN4 chloride channel, voltage-sensitive 4 -2.0337
SCD5 stearoyl-CoA desaturase 5 -2.02956
ARHGAP1 Rho GTPase activating protein 1 -2.00471