FREM2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description FRAS1 related extracellular matrix protein 2|This gene encodes an integral membrane protein containing numerous CSPG (chondroitin sulfate proteoglycan element) repeats and Calx-beta domains. The encoded protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions. This protein is important for the integrity of skin and renal epithelia. Mutations in this gene are associated with Fraser syndrome. [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 341640)
External Link http://www.ncbi.nlm.nih.gov/gene/341640
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Genes

2 interacting proteins for FREM2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
RYK receptor-like tyrosine kinase