FYB Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description FYN binding protein|The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011] (NCBI Entrez Gene Database, 2533)
External Link http://www.ncbi.nlm.nih.gov/gene/2533
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Genes

72 interacting proteins for FYB from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
BCAR1 breast cancer anti-estrogen resistance 1
BCL10 B-cell CLL/lymphoma 10
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BTK Bruton agammaglobulinemia tyrosine kinase
C11ORF31 chromosome 11 open reading frame 31
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CARD11 caspase recruitment domain family, member 11
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CD247 CD247 molecule
CD2AP CD2-associated protein
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CKAP5 cytoskeleton associated protein 5
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CNOT1 CCR4-NOT transcription complex, subunit 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CTTN cortactin
DARS aspartyl-tRNA synthetase
DNM2 dynamin 2
DNM3 dynamin 3
DOCK2 dedicator of cytokinesis 2
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
ENAH enabled homolog (Drosophila)
EVL Enah/Vasp-like
FAM175B family with sequence similarity 175, member B
FASLG Fas ligand (TNF superfamily, member 6)
FER fer (fps/fes related) tyrosine kinase
FUS FUS RNA binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HSPG2 heparan sulfate proteoglycan 2
KRT33A keratin 33A, type I
KRT36 keratin 36, type I
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LRRK1 leucine-rich repeat kinase 1
MAP3K7 mitogen-activated protein kinase kinase kinase 7
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NCKIPSD NCK interacting protein with SH3 domain
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCG1 phospholipase C, gamma 1
PRKCQ protein kinase C, theta
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRA protein tyrosine phosphatase, receptor type, A
RASA1 RAS p21 protein activator (GTPase activating protein) 1
SH2D1A SH2 domain containing 1A
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SKAP1 src kinase associated phosphoprotein 1
SKAP2 src kinase associated phosphoprotein 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TFG TRK-fused gene
UBASH3B ubiquitin associated and SH3 domain containing B
UBC ubiquitin C
UBR4 ubiquitin protein ligase E3 component n-recognin 4
VASP vasodilator-stimulated phosphoprotein
WAS Wiskott-Aldrich syndrome