FYN Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description FYN proto-oncogene, Src family tyrosine kinase|This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2534)
External Link http://www.ncbi.nlm.nih.gov/gene/2534
Similar Terms
Downloads & Tools

Genes

71 substrates of the kinase FYN from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADD2 adducin 2 (beta)
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
APP amyloid beta (A4) precursor protein
ARHGAP33 Rho GTPase activating protein 33
BCR breakpoint cluster region
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD226 CD226 molecule
CD300LB CD300 molecule-like family member b
CD300LF CD300 molecule-like family member f
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD5 CD5 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDK5 cyclin-dependent kinase 5
CHN2 chimerin 2
CLIC5 chloride intracellular channel 5
CRMP1 collapsin response mediator protein 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CYTH1 cytohesin 1
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DLG2 discs, large homolog 2 (Drosophila)
DLG4 discs, large homolog 4 (Drosophila)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FLOT1 flotillin 1
FLOT2 flotillin 2
FYB FYN binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GRB10 growth factor receptor-bound protein 10
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
H3F3A H3 histone, family 3A
IFITM3 interferon induced transmembrane protein 3
ITCH itchy E3 ubiquitin protein ligase
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JUP junction plakoglobin
KIRREL kin of IRRE like (Drosophila)
MAP2 microtubule-associated protein 2
MAPK14 mitogen-activated protein kinase 14
MAPT microtubule-associated protein tau
NFE2L2 nuclear factor, erythroid 2-like 2
NMT1 N-myristoyltransferase 1
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
PECAM1 platelet/endothelial cell adhesion molecule 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PRKCD protein kinase C, delta
PROM1 prominin 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRJ protein tyrosine phosphatase, receptor type, J
PTPRT protein tyrosine phosphatase, receptor type, T
PXN paxillin
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RTN4 reticulon 4
SCN5A sodium channel, voltage gated, type V alpha subunit
SIGLEC10 sialic acid binding Ig-like lectin 10
SKAP1 src kinase associated phosphoprotein 1
SKAP2 src kinase associated phosphoprotein 2
SLAMF1 signaling lymphocytic activation molecule family member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STK11 serine/threonine kinase 11
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TOM1L1 target of myb1 (chicken)-like 1
WAS Wiskott-Aldrich syndrome