FZD2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description frizzled class receptor 2|This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways. [provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 2535)
External Link http://www.ncbi.nlm.nih.gov/gene/2535
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73 interacting proteins for FZD2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARR3 arrestin 3, retinal (X-arrestin)
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CDC42 cell division cycle 42
CLTA clathrin, light chain A
CLTB clathrin, light chain B
CLTC clathrin, heavy chain (Hc)
CSNK1A1 casein kinase 1, alpha 1
CSNK1G2 casein kinase 1, gamma 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DACT1 dishevelled-binding antagonist of beta-catenin 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK2 dickkopf WNT signaling pathway inhibitor 2
DKK4 dickkopf WNT signaling pathway inhibitor 4
DLG4 discs, large homolog 4 (Drosophila)
DVL1 dishevelled segment polarity protein 1
DVL2 dishevelled segment polarity protein 2
DVL3 dishevelled segment polarity protein 3
FKBP1A FK506 binding protein 1A, 12kDa
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG5 guanine nucleotide binding protein (G protein), gamma 5
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNG8 guanine nucleotide binding protein (G protein), gamma 8
KREMEN1 kringle containing transmembrane protein 1
KREMEN2 kringle containing transmembrane protein 2
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NOS3 nitric oxide synthase 3 (endothelial cell)
PARD6A par-6 family cell polarity regulator alpha
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCG protein kinase C, gamma
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
ROR2 receptor tyrosine kinase-like orphan receptor 2
SAG S-antigen; retina and pineal gland (arrestin)
SOST sclerostin
SPHK1 sphingosine kinase 1
UBC ubiquitin C
WNT3A wingless-type MMTV integration site family, member 3A
WNT5A wingless-type MMTV integration site family, member 5A
YES1 YES proto-oncogene 1, Src family tyrosine kinase