| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | frizzled class receptor 4|This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8322) |
| External Link | https://ncbi.nlm.nih.gov/gene/8322 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the FZD4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.0138408 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0136595 |
| XIC | X chromosome inactivation center | 0.011872 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0117104 |
| RGS5 | regulator of G-protein signaling 5 | 0.0105952 |
| RTN2 | reticulon 2 | 0.0104131 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.0101133 |
| TXNDC9 | thioredoxin domain containing 9 | 0.0100995 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0100877 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00979477 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00978545 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00956948 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00935766 |
| BAG3 | BCL2-associated athanogene 3 | 0.00934017 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00929273 |
| FGF13 | fibroblast growth factor 13 | 0.00925687 |
| DUSP5 | dual specificity phosphatase 5 | 0.00920114 |
| PCLAF | PCNA clamp associated factor | 0.00905566 |
| S100A7 | S100 calcium binding protein A7 | 0.00902401 |
| TOX3 | TOX high mobility group box family member 3 | 0.00899449 |
| EVI2A | ecotropic viral integration site 2A | 0.0089886 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00863173 |
| WBP5 | WW domain binding protein 5 | 0.00853263 |
| FAM46C | family with sequence similarity 46, member C | 0.00851218 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00834418 |
| SLC25A46 | solute carrier family 25, member 46 | 0.00833472 |
| MIR22HG | MIR22 host gene | 0.00822029 |
| S100P | S100 calcium binding protein P | 0.00818888 |
| PWP1 | PWP1 homolog (S. cerevisiae) | 0.00810187 |
| CCP110 | centriolar coiled coil protein 110kDa | 0.00800378 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00797809 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00793417 |
| STC1 | stanniocalcin 1 | 0.00793415 |
| VAMP7 | vesicle-associated membrane protein 7 | 0.00789714 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00785128 |
| PLK2 | polo-like kinase 2 | 0.00782774 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | 0.00780498 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00772361 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00767764 |
| LAGE3 | L antigen family, member 3 | 0.00758633 |
| S100A8 | S100 calcium binding protein A8 | 0.00757378 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00750455 |
| BEX4 | brain expressed, X-linked 4 | 0.00745615 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00743913 |
| IL6ST | interleukin 6 signal transducer | 0.00738206 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | 0.00725649 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.0072128 |
| CCDC86 | coiled-coil domain containing 86 | 0.00720453 |
| RAB5A | RAB5A, member RAS oncogene family | 0.00710658 |
| MYDGF | myeloid-derived growth factor | 0.00706872 |
| DEFB4A | defensin, beta 4A | 0.00699389 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00696625 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | 0.00696156 |
| DIO2 | deiodinase, iodothyronine, type II | 0.00692401 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00689753 |
| COMMD3 | COMM domain containing 3 | 0.00682001 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00681922 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00678235 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | 0.00675563 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00671537 |
| MITF | microphthalmia-associated transcription factor | 0.0066771 |
| BAG2 | BCL2-associated athanogene 2 | 0.00666784 |
| COX7B | cytochrome c oxidase subunit VIIb | 0.00666293 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00665175 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00662246 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00658541 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00656308 |
| PLK1 | polo-like kinase 1 | 0.00655416 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00655317 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.0065442 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00652358 |
| STOM | stomatin | 0.00650448 |
| PTTG1 | pituitary tumor-transforming 1 | 0.00648195 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0064492 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 0.0064249 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.0063891 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | 0.006371 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00635037 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00631721 |
| S100A9 | S100 calcium binding protein A9 | 0.00630815 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00628142 |
| PLXNC1 | plexin C1 | 0.00626829 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00620897 |
| CENPU | centromere protein U | 0.0061986 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 0.00619469 |
| GTPBP8 | GTP-binding protein 8 (putative) | 0.00616555 |
| MAGEA3 | melanoma antigen family A3 | 0.00616444 |
| SSX1 | synovial sarcoma, X breakpoint 1 | 0.00616032 |
| PLN | phospholamban | 0.00615751 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0061238 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) | 0.00610616 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.00606841 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00601883 |
| GAL | galanin/GMAP prepropeptide | 0.00599937 |
| NDUFB3 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | 0.00599094 |
| NVL | nuclear VCP-like | 0.00597053 |
| FADS1 | fatty acid desaturase 1 | 0.00596468 |
| MAOA | monoamine oxidase A | 0.00595806 |
| PLS1 | plastin 1 | 0.00589429 |
| S100A12 | S100 calcium binding protein A12 | 0.00588876 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00588799 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.00588613 |
| TMC5 | transmembrane channel-like 5 | 0.00586429 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.00581631 |
| GPC4 | glypican 4 | 0.00580695 |
| LTF | lactotransferrin | 0.00579516 |
| TBX3 | T-box 3 | 0.00579131 |
| SALL1 | spalt-like transcription factor 1 | 0.00578316 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa | 0.00573704 |
| AXIN1 | axin 1 | 0.0057348 |
| FRZB | frizzled-related protein | 0.00572488 |
| MPDZ | multiple PDZ domain protein | 0.00572074 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | 0.00571468 |
| MRPS33 | mitochondrial ribosomal protein S33 | 0.00568752 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.00568598 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0056797 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.00564521 |
| CLC | Charcot-Leyden crystal galectin | 0.00561716 |
| CRYAB | crystallin, alpha B | 0.00560946 |
| RAB9A | RAB9A, member RAS oncogene family | 0.00560407 |
| MCOLN1 | mucolipin 1 | 0.00559239 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00558723 |
| RPL26L1 | ribosomal protein L26-like 1 | 0.00558047 |
| VCAN | versican | 0.00558028 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00557966 |
| SEC61B | Sec61 beta subunit | 0.00556757 |
| RNF167 | ring finger protein 167 | 0.00553484 |
| DLL3 | delta-like 3 (Drosophila) | 0.00552946 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00552454 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.00552259 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00547547 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0054585 |
| CYTIP | cytohesin 1 interacting protein | 0.00545665 |
| CORO1C | coronin, actin binding protein, 1C | 0.00543906 |
| LST1 | leukocyte specific transcript 1 | 0.00542857 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase | 0.0054229 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00542128 |
| NDUFA6 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | 0.00541499 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.00540384 |
| DUOX2 | dual oxidase 2 | 0.00538444 |
| CGA | glycoprotein hormones, alpha polypeptide | 0.00538426 |
| WASHC3 | WASH complex subunit 3 | 0.00538291 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00537816 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | 0.0053741 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.00536787 |
| TSPAN1 | tetraspanin 1 | 0.00535671 |
| PLA2G2D | phospholipase A2, group IID | 0.00535502 |
| RAB4A | RAB4A, member RAS oncogene family | 0.00533668 |
| RGS2 | regulator of G-protein signaling 2 | 0.00532321 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00531516 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.00531025 |
| MME | membrane metallo-endopeptidase | 0.00529232 |
| ATF3 | activating transcription factor 3 | 0.00528477 |
| CCNB1 | cyclin B1 | 0.00528125 |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 | 0.00527707 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00527318 |
| PRDX3 | peroxiredoxin 3 | 0.00526953 |
| ATG3 | autophagy related 3 | 0.00524531 |
| STK26 | serine/threonine protein kinase 26 | 0.0052453 |
| ANOS1 | anosmin 1 | 0.00524103 |
| HOPX | HOP homeobox | 0.00523694 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.00523577 |
| HBD | hemoglobin, delta | 0.00523476 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00520062 |
| TDG | thymine-DNA glycosylase | 0.00518135 |
| RAB32 | RAB32, member RAS oncogene family | 0.00518116 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00517587 |
| FASN | fatty acid synthase | 0.00517093 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | 0.00516865 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | 0.00516587 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.00516285 |
| CLIC2 | chloride intracellular channel 2 | 0.00515935 |
| VNN2 | vanin 2 | 0.00515667 |
| SH2B2 | SH2B adaptor protein 2 | 0.00515645 |
| TMEM159 | transmembrane protein 159 | 0.00514571 |
| SDF2L1 | stromal cell-derived factor 2-like 1 | 0.00513515 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | 0.00512423 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00510607 |
| AIM2 | absent in melanoma 2 | 0.00509664 |
| CRY1 | cryptochrome circadian clock 1 | 0.00509361 |
| GTF2B | general transcription factor IIB | 0.00508996 |
| ADM | adrenomedullin | 0.00508849 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | 0.00507262 |
| RPS27L | ribosomal protein S27-like | 0.00505598 |
| PLIN2 | perilipin 2 | 0.00505258 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.00503647 |
| PPAP2A | phosphatidic acid phosphatase type 2A | 0.00503516 |
| ABHD4 | abhydrolase domain containing 4 | 0.00503069 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.00502741 |
| PLXDC1 | plexin domain containing 1 | 0.00501769 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.005008 |
| APLNR | apelin receptor | 0.00500586 |
| ISCU | iron-sulfur cluster assembly enzyme | 0.00499803 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | 0.00499075 |
| STX3 | syntaxin 3 | 0.00497897 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | 0.00496507 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00494804 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00493144 |
| MAMLD1 | mastermind-like domain containing 1 | 0.00491958 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00491121 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 0.00490863 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00490655 |
| GMFG | glia maturation factor, gamma | 0.00489084 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | 0.00488605 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | 0.00487898 |
| CD2 | CD2 molecule | 0.00486847 |
| HSPA14 | heat shock 70kDa protein 14 | 0.00485102 |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.00484763 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.0048435 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00483489 |
| WAC | WW domain containing adaptor with coiled-coil | 0.00483286 |
| PSMA5 | proteasome (prosome, macropain) subunit, alpha type, 5 | 0.00483071 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa | 0.0048231 |
| SP110 | SP110 nuclear body protein | 0.00481607 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.00481517 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.00480701 |
| CD86 | CD86 molecule | 0.00480473 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00480068 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00479251 |
| DCTN6 | dynactin 6 | 0.00478791 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00477711 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00477018 |
| GTPBP2 | GTP binding protein 2 | 0.00476682 |
| NTS | neurotensin | 0.0047631 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00476166 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00476052 |
| MRPS2 | mitochondrial ribosomal protein S2 | 0.00476017 |
| NANOG | Nanog homeobox | 0.00475761 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.0047539 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.00475387 |
| AFF1 | AF4/FMR2 family, member 1 | 0.004753 |
| LYZ | lysozyme | 0.00474917 |
| SRPRB | signal recognition particle receptor, B subunit | 0.00474715 |
| CCDC47 | coiled-coil domain containing 47 | 0.00474708 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 | 0.00474169 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00473966 |
| QKI | QKI, KH domain containing, RNA binding | 0.00472985 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 0.00472922 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00472595 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.00470468 |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) | 0.0046945 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00468721 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0046816 |
| TRIB2 | tribbles pseudokinase 2 | 0.00468058 |
| REG1A | regenerating islet-derived 1 alpha | 0.0046775 |
| ATP5MJ | ATP synthase membrane subunit j | 0.00467586 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00467579 |
| SSR4 | signal sequence receptor, delta | 0.00466853 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.00466371 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT19 | keratin 19, type I | -0.0172654 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.0148913 |
| ALB | albumin | -0.0146124 |
| KRT14 | keratin 14, type I | -0.0142465 |
| AUTS2 | autism susceptibility candidate 2 | -0.013988 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.013902 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0133645 |
| KRT5 | keratin 5, type II | -0.0121468 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0112487 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0107258 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.010673 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.0104752 |
| CHEK1 | checkpoint kinase 1 | -0.0103265 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.01031 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0102311 |
| MMP7 | matrix metallopeptidase 7 | -0.010168 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0100115 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00985783 |
| MUC16 | mucin 16, cell surface associated | -0.00980219 |
| DSP | desmoplakin | -0.00968366 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00961336 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00960754 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00958199 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00952201 |
| APOA2 | apolipoprotein A-II | -0.00951363 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00942912 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00942675 |
| H1-0 | H1.0 linker histone | -0.00942031 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00939671 |
| CD9 | CD9 molecule | -0.00938648 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00938456 |
| LAMB3 | laminin, beta 3 | -0.00925518 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00923963 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00899057 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00896599 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00887749 |
| VSNL1 | visinin-like 1 | -0.00871571 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00854026 |
| KRT18 | keratin 18, type I | -0.00851297 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00850974 |
| APOA1 | apolipoprotein A-I | -0.00838544 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00806934 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00803413 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0080203 |
| WT1 | Wilms tumor 1 | -0.00798672 |
| S100A2 | S100 calcium binding protein A2 | -0.00788482 |
| NDP | Norrie disease (pseudoglioma) | -0.00782399 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00775494 |
| STMN2 | stathmin 2 | -0.00762175 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00759877 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00756368 |
| GPC3 | glypican 3 | -0.00750079 |
| C1RL | complement component 1, r subcomponent-like | -0.00744455 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.00739514 |
| AHSG | alpha-2-HS-glycoprotein | -0.00739001 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00737998 |
| HLA-F | major histocompatibility complex, class I, F | -0.00733727 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.0073319 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00732552 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0072997 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.00728292 |
| CD99 | CD99 molecule | -0.0072794 |
| FABP1 | fatty acid binding protein 1, liver | -0.00725558 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00719173 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00716839 |
| CTSZ | cathepsin Z | -0.00716547 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | -0.00716049 |
| TBC1D16 | TBC1 domain family, member 16 | -0.00715912 |
| COL1A2 | collagen, type I, alpha 2 | -0.0071459 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00712692 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | -0.00711534 |
| SIRT3 | sirtuin 3 | -0.00711347 |
| RPIA | ribose 5-phosphate isomerase A | -0.00711149 |
| ADD3 | adducin 3 (gamma) | -0.0070851 |
| PCP4 | Purkinje cell protein 4 | -0.00708363 |
| FGG | fibrinogen gamma chain | -0.00705662 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | -0.00705099 |
| AREG | amphiregulin | -0.00693421 |
| MB | myoglobin | -0.00690137 |
| IL1R1 | interleukin 1 receptor, type I | -0.00689702 |
| MEIS1 | Meis homeobox 1 | -0.00688032 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00685651 |
| TTR | transthyretin | -0.00681453 |
| KRT15 | keratin 15, type I | -0.00678314 |
| COQ8A | coenzyme Q8A | -0.00675604 |
| PENK | proenkephalin | -0.0067496 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -0.00674708 |
| PERP | PERP, TP53 apoptosis effector | -0.00673829 |
| HLA-B | major histocompatibility complex, class I, B | -0.00673704 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00672562 |
| KRT8 | keratin 8, type II | -0.00670543 |
| STK10 | serine/threonine kinase 10 | -0.00670543 |
| TPM2 | tropomyosin 2 (beta) | -0.00668133 |
| PEG3 | paternally expressed 3 | -0.00666658 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.00665373 |
| AFP | alpha-fetoprotein | -0.00661958 |
| SRPRA | SRP receptor subunit alpha | -0.00661639 |
| ENG | endoglin | -0.00658796 |
| RECQL | RecQ helicase-like | -0.00656892 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00656122 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00650223 |
| SYNM | synemin, intermediate filament protein | -0.00649006 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | -0.00648568 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | -0.0064777 |
| PRSS3 | protease, serine, 3 | -0.00643507 |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 | -0.00642791 |
| GAS6 | growth arrest-specific 6 | -0.00642513 |
| FOLR1 | folate receptor 1 (adult) | -0.00642502 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.00636471 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.00635004 |
| APOB | apolipoprotein B | -0.00632997 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | -0.00632841 |
| VTN | vitronectin | -0.00621694 |
| MGP | matrix Gla protein | -0.00620196 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00616659 |
| CRP | C-reactive protein, pentraxin-related | -0.0061285 |
| DCPS | decapping enzyme, scavenger | -0.00612018 |
| HAMP | hepcidin antimicrobial peptide | -0.006103 |
| PKP2 | plakophilin 2 | -0.00608389 |
| SERPINA6 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 | -0.00604189 |
| GAS1 | growth arrest-specific 1 | -0.00602571 |
| HLA-C | major histocompatibility complex, class I, C | -0.00601283 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00597934 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00596103 |
| FKBP5 | FK506 binding protein 5 | -0.00596031 |
| MLF2 | myeloid leukemia factor 2 | -0.0059519 |
| ITGA6 | integrin, alpha 6 | -0.00593969 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | -0.0059303 |
| FBXO21 | F-box protein 21 | -0.00591168 |
| IL1A | interleukin 1, alpha | -0.00590145 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | -0.00589933 |
| TPBG | trophoblast glycoprotein | -0.00588251 |
| PROM1 | prominin 1 | -0.0058683 |
| EMX2 | empty spiracles homeobox 2 | -0.00586398 |
| TRIM29 | tripartite motif containing 29 | -0.00585315 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00584986 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0058393 |
| CDR1 | cerebellar degeneration-related protein 1, 34kDa | -0.00583552 |
| ATP11B | ATPase, class VI, type 11B | -0.00583346 |
| ABHD2 | abhydrolase domain containing 2 | -0.00583303 |
| IL1R2 | interleukin 1 receptor, type II | -0.00582058 |
| MXRA7 | matrix-remodelling associated 7 | -0.00579947 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00577533 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.00576613 |
| LEFTY1 | left-right determination factor 1 | -0.00575517 |
| HAT1 | histone acetyltransferase 1 | -0.00575287 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.00573733 |
| MSLN | mesothelin | -0.0057081 |
| IL7 | interleukin 7 | -0.00568738 |
| SPATA20 | spermatogenesis associated 20 | -0.00568645 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.00568552 |
| GCG | glucagon | -0.00568489 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00568319 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | -0.00565817 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.00563362 |
| PEG10 | paternally expressed 10 | -0.00562256 |
| IL10RB | interleukin 10 receptor, beta | -0.00562239 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -0.00561418 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00560795 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.00559768 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00558717 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00558005 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00555722 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00555241 |
| PTDSS1 | phosphatidylserine synthase 1 | -0.00554076 |
| KRT23 | keratin 23, type I | -0.00553654 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00552051 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00550853 |
| RTN1 | reticulon 1 | -0.00550684 |
| IREB2 | iron-responsive element binding protein 2 | -0.00550452 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.00550376 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | -0.00546371 |
| CPA1 | carboxypeptidase A1 (pancreatic) | -0.005459 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.00545638 |
| KRT17 | keratin 17, type I | -0.00545179 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.00541524 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -0.00541096 |
| UXS1 | UDP-glucuronate decarboxylase 1 | -0.0053943 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.00538117 |
| SCG5 | secretogranin V | -0.00537526 |
| TMEM106C | transmembrane protein 106C | -0.00536778 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00536486 |
| TP53I3 | tumor protein p53 inducible protein 3 | -0.0053486 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | -0.00532243 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0053211 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | -0.00531675 |
| EMP1 | epithelial membrane protein 1 | -0.00530467 |
| APOC3 | apolipoprotein C-III | -0.00530396 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00528709 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00528146 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00526095 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00524942 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | -0.00524678 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00523006 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.00522905 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.00521904 |
| MPZL2 | myelin protein zero-like 2 | -0.00521789 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00519462 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00519423 |
| SNX7 | sorting nexin 7 | -0.0051852 |
| FOCAD | focadhesin | -0.00518502 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | -0.00518212 |
| AOC1 | amine oxidase, copper containing 1 | -0.0051769 |
| S100A10 | S100 calcium binding protein A10 | -0.00515592 |
| TAGLN | transgelin | -0.00513152 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.00513145 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | -0.00512223 |
| CBS | cystathionine-beta-synthase | -0.0051153 |
| ASRGL1 | asparaginase like 1 | -0.00511344 |
| APH1A | APH1A gamma secretase subunit | -0.00510651 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.00510474 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00509712 |
| ESM1 | endothelial cell-specific molecule 1 | -0.00509495 |
| NUP160 | nucleoporin 160kDa | -0.00509062 |
| ANXA4 | annexin A4 | -0.00508626 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.00507592 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.00507506 |
| FGF9 | fibroblast growth factor 9 | -0.0050735 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00507142 |
| AUP1 | ancient ubiquitous protein 1 | -0.00506395 |
| STC2 | stanniocalcin 2 | -0.00506316 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.00505704 |
| GAS2 | growth arrest-specific 2 | -0.00505701 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | -0.00504733 |
| AGXT | alanine-glyoxylate aminotransferase | -0.00501661 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.0050148 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | -0.00499908 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00499733 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.00499082 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.00498711 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.0049796 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | -0.00497791 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | -0.00496899 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00496089 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00495681 |
| MEN1 | multiple endocrine neoplasia I | -0.00495625 |
| TNNC1 | troponin C type 1 (slow) | -0.0049377 |
| PLA2G1B | phospholipase A2, group IB (pancreas) | -0.00493214 |
| CYB561 | cytochrome b561 | -0.00492553 |
| SST | somatostatin | -0.00492261 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00491943 |
| APMAP | adipocyte plasma membrane associated protein | -0.00491356 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00491332 |
| POU4F1 | POU class 4 homeobox 1 | -0.00491171 |
| GPR161 | G protein-coupled receptor 161 | -0.00490982 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.00490643 |
| COPS7A | COP9 signalosome subunit 7A | -0.0049058 |
| GTF2I | general transcription factor IIi | -0.00490371 |
| TM7SF3 | transmembrane 7 superfamily member 3 | -0.00490092 |
