FZD7 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description frizzled class receptor 7|Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8324)
Similar Terms
Downloads & Tools

Genes

260 genes differentially expressed following the FZD7 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ANGPTL3 angiopoietin-like 3 2.80795
MYOM2 myomesin 2 2.80795
GPR25 G protein-coupled receptor 25 2.80795
ASB17 ankyrin repeat and SOCS box containing 17 2.80795
EPHX4 epoxide hydrolase 4 2.80795
PAX2 paired box 2 2.80795
DSG3 desmoglein 3 2.80795
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 2.80795
CCL5 chemokine (C-C motif) ligand 5 2.80795
OSR2 odd-skipped related transciption factor 2 2.80795
SLC25A41 solute carrier family 25, member 41 2.80795
NRAP nebulin-related anchoring protein 2.80795
AFM afamin 2.80795
RRAD Ras-related associated with diabetes 2.80795
NCF1 neutrophil cytosolic factor 1 2.80795
IGFL2 IGF-like family member 2 2.80795
ADGRE1 adhesion G protein-coupled receptor E1 2.80795
MYOM3 myomesin 3 2.80795
NRROS negative regulator of reactive oxygen species 2.80795
ASCL3 achaete-scute family bHLH transcription factor 3 2.80795
IRX4 iroquois homeobox 4 2.80795
ANKRD30A ankyrin repeat domain 30A 2.80795
SPDEF SAM pointed domain containing ETS transcription factor 2.80795
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.80795
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 2.80795
METTL21C methyltransferase like 21C 2.80795
BTBD16 BTB (POZ) domain containing 16 2.80795
IL23R interleukin 23 receptor 2.80795
FAM9C family with sequence similarity 9, member C 2.80795
SP6 Sp6 transcription factor 2.80795
MRC1 mannose receptor, C type 1 2.80795
MYO1G myosin IG 2.80795
NEUROG3 neurogenin 3 2.80795
SPP2 secreted phosphoprotein 2, 24kDa 2.80795
ARSI arylsulfatase family, member I 2.80795
PI16 peptidase inhibitor 16 2.80795
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.80795
ASB5 ankyrin repeat and SOCS box containing 5 2.80795
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 2.80795
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 2.80795
CSN1S1 casein alpha s1 2.80795
HTRA4 HtrA serine peptidase 4 2.80795
SIM1 single-minded family bHLH transcription factor 1 2.80795
GPX5 glutathione peroxidase 5 2.80795
MT3 metallothionein 3 2.80795
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 2.80795
SEPTIN12 septin 12 2.80795
SERTM2 serine rich and transmembrane domain containing 2 2.80795
H3C14 H3 clustered histone 14 2.80795
H3-7 H3.7 histone (putative) 2.80795
CTXND1 cortexin domain containing 1 2.80795
H2BK1 H2B.K variant histone 1 2.80795
EXOC1L exocyst complex component 1 like 2.80795
C10ORF53 chromosome 10 open reading frame 53 2.80795
TSPAN1 tetraspanin 1 2.80795
HLX H2.0-like homeobox 2.80795
OVGP1 oviductal glycoprotein 1, 120kDa 2.80795
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 2.80795
IZUMO4 IZUMO family member 4 2.80795
ZNF436 zinc finger protein 436 2.80795
PCDHB12 protocadherin beta 12 2.80795
VIT vitrin 2.80795
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 2.80795
MAG myelin associated glycoprotein 2.80795
TFEC transcription factor EC 2.80795
GJD2 gap junction protein, delta 2, 36kDa 2.80795
TSPO2 translocator protein 2 2.80795
SYT15 synaptotagmin XV 2.80795
GATA4 GATA binding protein 4 2.80795
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 2.80795
C15ORF62 chromosome 15 open reading frame 62 2.80795
FAM90A11 family with sequence similarity 90 member A11 2.80795
TEKT2 tektin 2 (testicular) 2.80795
CST1 cystatin SN 2.80795
ZNF541 zinc finger protein 541 2.80795
SLC36A3 solute carrier family 36, member 3 2.80795
MRLN myoregulin 2.80795
MR1 major histocompatibility complex, class I-related 2.80795
SOWAHA sosondowah ankyrin repeat domain family member A 2.80795
EPYC epiphycan 2.80795
SMIM22 small integral membrane protein 22 2.80795
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 2.80795
CRHBP corticotropin releasing hormone binding protein 2.80795
TPSB2 tryptase beta 2 (gene/pseudogene) 2.80795
NR5A1 nuclear receptor subfamily 5, group A, member 1 2.80795
GPR12 G protein-coupled receptor 12 2.80795
EHF ets homologous factor 2.80795
DRD5 dopamine receptor D5 2.80795
TEKT1 tektin 1 2.80795
FIBIN fin bud initiation factor homolog (zebrafish) 2.80795
PAGE4 P antigen family, member 4 (prostate associated) 2.80795
CPA2 carboxypeptidase A2 (pancreatic) 2.80795
HKDC1 hexokinase domain containing 1 2.80795
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 2.80795
FBXO40 F-box protein 40 2.80795
C20ORF144 chromosome 20 open reading frame 144 2.80795
FSHR follicle stimulating hormone receptor 2.80795
C8G complement component 8, gamma polypeptide 2.80795
CDH17 cadherin 17, LI cadherin (liver-intestine) 2.80795
GPR62 G protein-coupled receptor 62 2.80795
IDI2 isopentenyl-diphosphate delta isomerase 2 2.80795
POU3F3 POU class 3 homeobox 3 2.80795
NPAS4 neuronal PAS domain protein 4 2.80795
GCM1 glial cells missing homolog 1 (Drosophila) 2.80795
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 2.80795
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 2.80795
GRAP2 GRB2-related adaptor protein 2 2.80795
PDK4 pyruvate dehydrogenase kinase, isozyme 4 2.80795
SYTL4 synaptotagmin-like 4 2.80795
IL10RA interleukin 10 receptor, alpha 2.80795
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 2.80795
TEX38 testis expressed 38 2.80795
TGM3 transglutaminase 3 2.80795
PF4V1 platelet factor 4 variant 1 2.80795
CCDC70 coiled-coil domain containing 70 2.80795
PCDHAC2 protocadherin alpha subfamily C, 2 2.80795
PXT1 peroxisomal, testis specific 1 2.80795
PLCD4 phospholipase C, delta 4 2.80795
PAGE2B P antigen family, member 2B 2.80795
CD27 CD27 molecule 2.80795
CFI complement factor I 2.80795
HMGB4 high mobility group box 4 2.80795
GDI2 GDP dissociation inhibitor 2 2.80795
RBBP8NL RBBP8 N-terminal like 2.80795
OR13G1 olfactory receptor, family 13, subfamily G, member 1 2.80795
FAM47E family with sequence similarity 47, member E 2.6839
NES nestin 2.55621
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa 2.55621
BRMS1 breast cancer metastasis suppressor 1 2.53374
PWWP3B PWWP domain containing 3B 2.52795
CEMIP cell migration inducing protein, hyaluronan binding 2.48871
TMEM259 transmembrane protein 259 2.48871
ATP5PO ATP synthase peripheral stalk subunit OSCP 2.4558
NPIPB12 nuclear pore complex interacting protein family member B12 2.39665
RBAK RB-associated KRAB zinc finger 2.39665
MTX2 metaxin 2 2.38405
ZNF584 zinc finger protein 584 2.36723
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 2.34248
KIN Kin17 DNA and RNA binding protein 2.2997
KLLN killin, p53-regulated DNA replication inhibitor 2.24301
SNF8 SNF8, ESCRT-II complex subunit 2.23633
ACKR3 atypical chemokine receptor 3 2.23461
F2 coagulation factor II (thrombin) 2.23461
ANO3 anoctamin 3 2.23461
ARMH1 armadillo like helical domain containing 1 2.23404
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 2.23404
CEP126 centrosomal protein 126kDa 2.23404
ACKR2 atypical chemokine receptor 2 2.22713
PTGDR prostaglandin D2 receptor (DP) 2.22713
KIF13B kinesin family member 13B 2.21833
LEMD3 LEM domain containing 3 2.21833
RNF17 ring finger protein 17 2.21797
PRPF8 pre-mRNA processing factor 8 2.21536
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 2.20543
EPS8 epidermal growth factor receptor pathway substrate 8 2.19593
TIGD4 tigger transposable element derived 4 2.17439
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 2.16742
H2AC8 H2A clustered histone 8 2.16333
PNPLA1 patatin-like phospholipase domain containing 1 2.16045
H3C11 H3 clustered histone 11 2.15845
SNAI3 snail family zinc finger 3 2.15608
AMPH amphiphysin 2.15538
OSER1 oxidative stress responsive serine-rich 1 2.15151
SCN3B sodium channel, voltage gated, type III beta subunit 2.14576
TXNRD2 thioredoxin reductase 2 2.10816
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 2.09718
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 2.0949
KMT5A lysine methyltransferase 5A 2.07467
MAP3K10 mitogen-activated protein kinase kinase kinase 10 2.07467
ZNF576 zinc finger protein 576 2.07195
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 2.07001
NRL neural retina leucine zipper 2.04165
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 2.03034
DCP2 decapping mRNA 2 2.02952
COQ3 coenzyme Q3 methyltransferase 2.01913
ATG7 autophagy related 7 2.01789
PDE4DIP phosphodiesterase 4D interacting protein 2.00034
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like 2.00034

decreased expression

Symbol Name Standardized Value
SPMAP2L sperm microtubule associated protein 2 like -2.80795
GLUD2 glutamate dehydrogenase 2 -2.80795
PCDHB9 protocadherin beta 9 -2.80795
GRIA2 glutamate receptor, ionotropic, AMPA 2 -2.80795
LOC124906892 uncharacterized LOC124906892 -2.80795
ASGR2 asialoglycoprotein receptor 2 -2.80795
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -2.80795
LHX6 LIM homeobox 6 -2.80795
FXYD2 FXYD domain containing ion transport regulator 2 -2.80795
SHE Src homology 2 domain containing E -2.80795
UBIAD1 UbiA prenyltransferase domain containing 1 -2.80795
COL20A1 collagen, type XX, alpha 1 -2.80795
GJA4 gap junction protein, alpha 4, 37kDa -2.80795
ERAS ES cell expressed Ras -2.80795
SPMIP3 sperm microtubule inner protein 3 -2.80795
SPACDR sperm acrosome developmental regulator -2.80795
GPRASP3 G protein-coupled receptor associated sorting protein family member 3 -2.80795
LORICRIN loricrin cornified envelope precursor protein -2.80795
DOK7 docking protein 7 -2.80795
TRPA1 transient receptor potential cation channel, subfamily A, member 1 -2.80795
LTF lactotransferrin -2.80795
ASIC3 acid sensing (proton gated) ion channel 3 -2.80795
ZIC4 Zic family member 4 -2.80795
KLHL31 kelch-like family member 31 -2.80795
DTD2 D-tyrosyl-tRNA deacylase 2 (putative) -2.80795
IL12A interleukin 12A -2.80795
HSF5 heat shock transcription factor family member 5 -2.80795
LRRK2 leucine-rich repeat kinase 2 -2.80795
ADAM2 ADAM metallopeptidase domain 2 -2.80795
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 -2.80795
WFDC8 WAP four-disulfide core domain 8 -2.80795
AQP3 aquaporin 3 (Gill blood group) -2.80795
SLC38A8 solute carrier family 38, member 8 -2.80795
PHOX2A paired-like homeobox 2a -2.80795
NYX nyctalopin -2.80795
LRRN4 leucine rich repeat neuronal 4 -2.80795
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 -2.59324
SPDYE16 speedy/RINGO cell cycle regulator family member E16 -2.55621
EPCAM epithelial cell adhesion molecule -2.45334
TMEM213 transmembrane protein 213 -2.39665
PADI3 peptidyl arginine deiminase, type III -2.38398
URI1 URI1, prefoldin-like chaperone -2.2997
RXFP1 relaxin/insulin-like family peptide receptor 1 -2.28849
FZD7 frizzled class receptor 7 -2.25983
DIRAS1 DIRAS family, GTP-binding RAS-like 1 -2.23777
GIGYF1 GRB10 interacting GYF protein 1 -2.23461
MRPL4 mitochondrial ribosomal protein L4 -2.23204
ZNF618 zinc finger protein 618 -2.23178
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 -2.22615
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G -2.22212
ITM2C integral membrane protein 2C -2.21833
ZCCHC18 zinc finger, CCHC domain containing 18 -2.20251
PIAS4 protein inhibitor of activated STAT, 4 -2.1989
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -2.19593
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) -2.17426
COL28A1 collagen, type XXVIII, alpha 1 -2.17407
WRNIP1 Werner helicase interacting protein 1 -2.15608
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 -2.15151
CNTNAP2 contactin associated protein-like 2 -2.14838
ASCC3 activating signal cointegrator 1 complex subunit 3 -2.13988
MRPL42 mitochondrial ribosomal protein L42 -2.13392
SYNPO synaptopodin -2.10956
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) -2.10956
LRRC69 leucine rich repeat containing 69 -2.09987
DCAF4 DDB1 and CUL4 associated factor 4 -2.08454
CDCA5 cell division cycle associated 5 -2.07531
CPD carboxypeptidase D -2.07467
KCTD14 potassium channel tetramerization domain containing 14 -2.07195
FIP1L1 factor interacting with PAPOLA and CPSF1 -2.07195
C9ORF43 chromosome 9 open reading frame 43 -2.06741
LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 -2.06741
ASPN asporin -2.06741
PCDHB16 protocadherin beta 16 -2.06595
COX11 COX11 cytochrome c oxidase copper chaperone -2.06552
SEC24B SEC24 family member B -2.05814
UVRAG UV radiation resistance associated -2.05541
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -2.05257
RRP36 ribosomal RNA processing 36 homolog (S. cerevisiae) -2.03682
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 -2.03034
YTHDC1 YTH domain containing 1 -2.03034
MOB1A MOB kinase activator 1A -2.01913
HASPIN histone H3 associated protein kinase -2.00136