Familial Adenomatous Polyposis Gene Set

Dataset	DisGeNET Gene-Disease Associations
Category	disease or phenotype associations
Type	disease
Description	An autosomal dominant disease that is caused by mutations in the APC gene and involves formation of numerous polyps in the epithelium of the large intestine which are initially benign and later transform into colon cancer. (Human Disease Ontology, DOID_0050424)
External Link	https://www.disgenet.org/browser/0/1/0/C2674616
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Genes

11 genes associated with the disease Familial Adenomatous Polyposis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol	Name
AFAP1	actin filament associated protein 1
APC	adenomatous polyposis coli
FAP	fibroblast activation protein, alpha
MSH3	mutS homolog 3
MUTYH	mutY homolog
NTHL1	nth endonuclease III-like 1 (E. coli)
PLA2G1B	phospholipase A2, group IB (pancreas)
PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)
PLB1	phospholipase B1
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta