Fanconi Anemia pathway Gene Set
Dataset
Reactome Pathways 2014
Category
structural or functional annotations
Type
pathway
Description
Interstrand cross links (ICL) of DNA can be induced by both endogenous and exogenous ligands. ICL if not repaired will lead to cell death. ICL repair pathway, also known as Fanconi anemia pathway is the cellular response to this type of DNA damage. (Pathway Ontology , PW_0001065 )
External Link
http://www.reactome.org/PathwayBrowser/#/R-HSA-6783310
Similar Terms
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Genes
22 proteins participating in the Fanconi Anemia pathway pathway from the Reactome Pathways dataset.
Symbol
Name
ATM
ATM serine/threonine kinase
ATR
ATR serine/threonine kinase
BRCA1
breast cancer 1, early onset
BRCA2
breast cancer 2, early onset
FANCA
Fanconi anemia, complementation group A
FANCB
Fanconi anemia, complementation group B
FANCC
Fanconi anemia, complementation group C
FANCD2
Fanconi anemia, complementation group D2
FANCE
Fanconi anemia, complementation group E
FANCF
Fanconi anemia, complementation group F
FANCG
Fanconi anemia, complementation group G
FANCI
Fanconi anemia, complementation group I
FANCL
Fanconi anemia, complementation group L
FANCM
Fanconi anemia, complementation group M
PALB2
partner and localizer of BRCA2
RPS27A
ribosomal protein S27a
UBA52
ubiquitin A-52 residue ribosomal protein fusion product 1
UBB
ubiquitin B
UBC
ubiquitin C
UBE2T
ubiquitin-conjugating enzyme E2T
USP1
ubiquitin specific peptidase 1
ZBTB32
zinc finger and BTB domain containing 32
