Fanconi Syndrome Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A renal tubular transport disease of the proximal renal tubes characterized by glucosuria, phosphaturia, generalized aminoaciduria and HCO3 wasting. (Human Disease Ontology, DOID_1062)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D005198
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Genes

60 genes/proteins associated with the disease Fanconi Syndrome from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
FRTS1 Fanconi renotubular syndrome 2.88009
GPX3 glutathione peroxidase 3 2.88009
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 2.88009
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 2.88009
BCL2 B-cell CLL/lymphoma 2 1.84924
TNF tumor necrosis factor 1.78587
BCL2L1 BCL2-like 1 1.60921
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.60082
IFNG interferon, gamma 1.57924
MPO myeloperoxidase 1.57665
IL6 interleukin 6 1.4727
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.43455
VEGFA vascular endothelial growth factor A 1.41992
JUN jun proto-oncogene 1.41938
HMOX1 heme oxygenase 1 1.39952
RB1 retinoblastoma 1 1.39702
CAT catalase 1.39535
BAX BCL2-associated X protein 1.38584
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.37504
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.37047
DDIT3 DNA-damage-inducible transcript 3 1.34926
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.30238
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.27905
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.26856
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.22853
PARP1 poly (ADP-ribose) polymerase 1 1.18456
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.17034
KLF4 Kruppel-like factor 4 (gut) 1.17034
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.16866
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.16567
B2M beta-2-microglobulin 1.16236
ICAM1 intercellular adhesion molecule 1 1.15122
CDK6 cyclin-dependent kinase 6 1.12599
MMP9 matrix metallopeptidase 9 1.1253
FAS Fas cell surface death receptor 1.12426
ALB albumin 1.12254
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.1198
CDK4 cyclin-dependent kinase 4 1.11707
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.11673
TGFB1 transforming growth factor, beta 1 1.10803
IL1B interleukin 1, beta 1.10596
BID BH3 interacting domain death agonist 1.10211
ALAS2 5'-aminolevulinate synthase 2 1.09541
NOS3 nitric oxide synthase 3 (endothelial cell) 1.08619
ATF3 activating transcription factor 3 1.08266
CHD1 chromodomain helicase DNA binding protein 1 1.08126
TP53 tumor protein p53 1.07768
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.07482
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.06917
IL12A interleukin 12A 1.06771
NOS2 nitric oxide synthase 2, inducible 1.0637
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.06044
CD44 CD44 molecule (Indian blood group) 1.05461
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.05126
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.04538
BIRC5 baculoviral IAP repeat containing 5 1.03789
TYMS thymidylate synthetase 1.03159
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.02708
FOS FBJ murine osteosarcoma viral oncogene homolog 1.02003
CCL2 chemokine (C-C motif) ligand 2 1.01324