| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fedratinib (hydrochloride hydrate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fedratinib (hydrochloride hydrate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.131386 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.130749 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.126496 |
| NDRG1 | N-myc downstream regulated 1 | 0.122795 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0965482 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0954482 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.089064 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0846013 |
| LDHA | lactate dehydrogenase A | 0.0822953 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0805221 |
| CANX | calnexin | 0.0737893 |
| OGA | O-GlcNAcase | 0.0725792 |
| STC1 | stanniocalcin 1 | 0.0713698 |
| B2M | beta-2-microglobulin | 0.0707377 |
| VIM | vimentin | 0.0667408 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0659731 |
| SDC4 | syndecan 4 | 0.0654802 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0653854 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.065275 |
| FLNB | filamin B, beta | 0.0638416 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0607582 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.059377 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0569494 |
| COL3A1 | collagen, type III, alpha 1 | 0.0562196 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0533352 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0530319 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0529832 |
| SEPTIN9 | septin 9 | 0.0528732 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0513598 |
| UBC | ubiquitin C | 0.0512685 |
| ARRDC3 | arrestin domain containing 3 | 0.0483221 |
| MYOF | myoferlin | 0.0481152 |
| CD109 | CD109 molecule | 0.0465853 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0453649 |
| ACTG1 | actin gamma 1 | 0.0444066 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0431422 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0426684 |
| LOXL2 | lysyl oxidase-like 2 | 0.0419601 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0414782 |
| MT2A | metallothionein 2A | 0.0407461 |
| INSIG2 | insulin induced gene 2 | 0.0405985 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0405461 |
| FNIP1 | folliculin interacting protein 1 | 0.0402598 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0401805 |
| SBF2 | SET binding factor 2 | 0.0400767 |
| COPA | coatomer protein complex, subunit alpha | 0.0400113 |
| FAM107B | family with sequence similarity 107, member B | 0.0397946 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0393951 |
| RAI1 | retinoic acid induced 1 | 0.0389604 |
| NAV2 | neuron navigator 2 | 0.0387491 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0380663 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0379081 |
| INSIG1 | insulin induced gene 1 | 0.0378807 |
| USP34 | ubiquitin specific peptidase 34 | 0.0378498 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0376297 |
| TPM3 | tropomyosin 3 | 0.0375865 |
| ZNF292 | zinc finger protein 292 | 0.0366583 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0353296 |
| APP | amyloid beta (A4) precursor protein | 0.0352594 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0346627 |
| SETD5 | SET domain containing 5 | 0.0346267 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0345194 |
| ADM | adrenomedullin | 0.034286 |
| NGLY1 | N-glycanase 1 | 0.0341508 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0334891 |
| CD99 | CD99 molecule | 0.0334654 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.033339 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0332021 |
| SEPTIN7 | septin 7 | 0.0331335 |
| SPAG9 | sperm associated antigen 9 | 0.0331005 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0325323 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0320223 |
| SFTPA2 | surfactant protein A2 | 0.0319494 |
| SUCO | SUN domain containing ossification factor | 0.031877 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.031612 |
| FNBP1 | formin binding protein 1 | 0.0315944 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0315898 |
| GLG1 | golgi glycoprotein 1 | 0.0315427 |
| DSPP | dentin sialophosphoprotein | 0.0315031 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0313239 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0312149 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.031121 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0309396 |
| ATP13A3 | ATPase type 13A3 | 0.0306443 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0301617 |
| MSI2 | musashi RNA-binding protein 2 | 0.0300235 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0298853 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0298836 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0297841 |
| RASA2 | RAS p21 protein activator 2 | 0.029759 |
| MSN | moesin | 0.0296652 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0295872 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0293539 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0293334 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0293261 |
| C1D | C1D nuclear receptor corepressor | 0.029302 |
| MT1X | metallothionein 1X | 0.0291051 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.029088 |
| APAF1 | apoptotic peptidase activating factor 1 | 0.028978 |
| ASPH | aspartate beta-hydroxylase | 0.0289637 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL8A1 | collagen, type VIII, alpha 1 | -0.104568 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.104078 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.101715 |
| MEIS2 | Meis homeobox 2 | -0.0639234 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0569679 |
| NAV1 | neuron navigator 1 | -0.0510737 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0483971 |
| GLIS3 | GLIS family zinc finger 3 | -0.0483515 |
| MX2 | MX dynamin-like GTPase 2 | -0.0480673 |
| SUCNR1 | succinate receptor 1 | -0.0474213 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0464424 |
| CAVIN1 | caveolae associated protein 1 | -0.0427075 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0412524 |
| LOX | lysyl oxidase | -0.040781 |
| PODXL | podocalyxin-like | -0.0407426 |
| RNF213 | ring finger protein 213 | -0.0406448 |
| MAP1B | microtubule-associated protein 1B | -0.0387439 |
| TMSB10 | thymosin beta 10 | -0.0380065 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0351724 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0351602 |
| EHBP1 | EH domain binding protein 1 | -0.0338635 |
| TENM3 | teneurin transmembrane protein 3 | -0.0331124 |
| SP100 | SP100 nuclear antigen | -0.0323808 |
| EXT1 | exostosin glycosyltransferase 1 | -0.031295 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0287454 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0287088 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0271826 |
| S100A10 | S100 calcium binding protein A10 | -0.0270598 |
| RAD51B | RAD51 paralog B | -0.0269514 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0267275 |
| CUX1 | cut-like homeobox 1 | -0.0266962 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0265381 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0264351 |
| PRSS23 | protease, serine, 23 | -0.0259244 |
| RIGI | RNA sensor RIG-I | -0.0257489 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0257486 |
| S100A4 | S100 calcium binding protein A4 | -0.0254213 |
| FRMD5 | FERM domain containing 5 | -0.0253949 |
| PRRX1 | paired related homeobox 1 | -0.0253949 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0246784 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0246547 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0242414 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0239674 |
| PARD3 | par-3 family cell polarity regulator | -0.0238516 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0238345 |
| FN1 | fibronectin 1 | -0.0229454 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0228487 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0227342 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0222094 |
| VEGFC | vascular endothelial growth factor C | -0.0220857 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0218973 |
| HMGB1 | high mobility group box 1 | -0.0218465 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0217616 |
| RPL35A | ribosomal protein L35a | -0.0216125 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0215235 |
| TUBB | tubulin, beta class I | -0.0212603 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0212065 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0211037 |
| CEP112 | centrosomal protein 112kDa | -0.020995 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0208908 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0208301 |
| HOXD10 | homeobox D10 | -0.020676 |
| CDH13 | cadherin 13 | -0.0205894 |
| TPM1 | tropomyosin 1 (alpha) | -0.020431 |
| RPL36 | ribosomal protein L36 | -0.0204307 |
| CDK6 | cyclin-dependent kinase 6 | -0.0202119 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0197964 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0197393 |
| PLXNA2 | plexin A2 | -0.019715 |
| SLFN5 | schlafen family member 5 | -0.0194272 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0192966 |
| RPLP2 | ribosomal protein, large, P2 | -0.0191495 |
| PHPT1 | phosphohistidine phosphatase 1 | -0.018862 |
| DCLK2 | doublecortin-like kinase 2 | -0.0188266 |
| RPL28 | ribosomal protein L28 | -0.0187155 |
| PMP22 | peripheral myelin protein 22 | -0.0183563 |
| TRABD2B | TraB domain containing 2B | -0.0180016 |
| PCDH7 | protocadherin 7 | -0.017931 |
| EGFR | epidermal growth factor receptor | -0.0177719 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0177122 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0175403 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0174682 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.0174457 |
| RPL34 | ribosomal protein L34 | -0.017384 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0173627 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0173589 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | -0.0172567 |
| RPL35 | ribosomal protein L35 | -0.0172176 |
| SYT1 | synaptotagmin I | -0.0170638 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0170633 |
| RPS19 | ribosomal protein S19 | -0.0169798 |
| FRMD4A | FERM domain containing 4A | -0.0169359 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0168618 |
| EXOC4 | exocyst complex component 4 | -0.0166616 |
| AOPEP | aminopeptidase O (putative) | -0.0165132 |
| ODAD2 | outer dynein arm docking complex subunit 2 | -0.0164889 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.016487 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0162891 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0162377 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0162151 |
