| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fedratinib (hydrochloride hydrate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fedratinib (hydrochloride hydrate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | 0.223472 |
| SDC4 | syndecan 4 | 0.16928 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.156933 |
| NDRG1 | N-myc downstream regulated 1 | 0.146401 |
| ACTG1 | actin gamma 1 | 0.125681 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.102857 |
| FLNB | filamin B, beta | 0.10203 |
| TPM3 | tropomyosin 3 | 0.0936984 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0930715 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0903941 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0900858 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0845603 |
| RIOK3 | RIO kinase 3 | 0.0839766 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0839071 |
| LDHA | lactate dehydrogenase A | 0.083457 |
| EZR | ezrin | 0.0823088 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0818889 |
| UBC | ubiquitin C | 0.0771555 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.071533 |
| PCBP2 | poly(rC) binding protein 2 | 0.0701828 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0697334 |
| DSPP | dentin sialophosphoprotein | 0.0671537 |
| FAM107B | family with sequence similarity 107, member B | 0.0647525 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0639491 |
| ARRDC3 | arrestin domain containing 3 | 0.0631461 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0609472 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0598452 |
| MCL1 | myeloid cell leukemia 1 | 0.0576006 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0542712 |
| ITGA6 | integrin, alpha 6 | 0.0541801 |
| CAPRIN2 | caprin family member 2 | 0.0524199 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0523506 |
| DIAPH1 | diaphanous-related formin 1 | 0.0509022 |
| RCOR1 | REST corepressor 1 | 0.0504406 |
| AHNAK | AHNAK nucleoprotein | 0.0498716 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0495353 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0486122 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0484703 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0480157 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.04669 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0453688 |
| LAMC2 | laminin, gamma 2 | 0.0440022 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.0438578 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0433179 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0422566 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0420156 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0415583 |
| OGA | O-GlcNAcase | 0.0412529 |
| SNX9 | sorting nexin 9 | 0.0401813 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0400949 |
| SGMS2 | sphingomyelin synthase 2 | 0.0395284 |
| MSN | moesin | 0.0393057 |
| B2M | beta-2-microglobulin | 0.0391689 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0388954 |
| SPAG9 | sperm associated antigen 9 | 0.0384529 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0384255 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0384147 |
| ATP13A3 | ATPase type 13A3 | 0.0369916 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0367164 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0366454 |
| ASPH | aspartate beta-hydroxylase | 0.0365558 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0362393 |
| EMP1 | epithelial membrane protein 1 | 0.0358467 |
| KRT8 | keratin 8, type II | 0.0356806 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0356635 |
| PGK1 | phosphoglycerate kinase 1 | 0.035491 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0354373 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0354233 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0348051 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0344319 |
| VIM | vimentin | 0.0338272 |
| COPA | coatomer protein complex, subunit alpha | 0.0336178 |
| TMF1 | TATA element modulatory factor 1 | 0.0327814 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0326755 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0324475 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0319038 |
| WASF2 | WAS protein family, member 2 | 0.0315648 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0315178 |
| SMNDC1 | survival motor neuron domain containing 1 | 0.0314768 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0306681 |
| MMP1 | matrix metallopeptidase 1 | 0.0303627 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0302895 |
| MXD1 | MAX dimerization protein 1 | 0.0295246 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0292766 |
| ANXA1 | annexin A1 | 0.029122 |
| CTSB | cathepsin B | 0.0291111 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.028985 |
| SFTPA2 | surfactant protein A2 | 0.0289514 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0288431 |
| TLN1 | talin 1 | 0.0287724 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0287363 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0284342 |
| CCDC88A | coiled-coil domain containing 88A | 0.0281693 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0280752 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0280488 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0279331 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0273848 |
| FAM13A | family with sequence similarity 13, member A | 0.0273733 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0273612 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0272939 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.164461 |
| VCAN | versican | -0.106783 |
| PTMA | prothymosin, alpha | -0.093578 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0754271 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0734654 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.073006 |
| MYOF | myoferlin | -0.0726239 |
| PRELID2 | PRELI domain containing 2 | -0.0690827 |
| RRBP1 | ribosome binding protein 1 | -0.0646742 |
| LMO7 | LIM domain 7 | -0.0639115 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0632515 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0622203 |
| SP100 | SP100 nuclear antigen | -0.0575756 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0558653 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0557211 |
| LAMB3 | laminin, beta 3 | -0.0546097 |
| S100A10 | S100 calcium binding protein A10 | -0.0533411 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0500416 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0498932 |
| RPS24 | ribosomal protein S24 | -0.0496976 |
| IRF1 | interferon regulatory factor 1 | -0.0466821 |
| FOXO1 | forkhead box O1 | -0.0459182 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0444839 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0423918 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0422603 |
| FAT1 | FAT atypical cadherin 1 | -0.0411818 |
| RIGI | RNA sensor RIG-I | -0.0404486 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0404107 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0403347 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0402902 |
| NPSR1 | neuropeptide S receptor 1 | -0.0399545 |
| CDK6 | cyclin-dependent kinase 6 | -0.0395957 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0395953 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0381585 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0376467 |
| DST | dystonin | -0.0364139 |
| RPL35A | ribosomal protein L35a | -0.0360763 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0354871 |
| RNF213 | ring finger protein 213 | -0.0347087 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.034572 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0343334 |
| DIAPH2 | diaphanous-related formin 2 | -0.0336254 |
| RPLP1 | ribosomal protein, large, P1 | -0.0328129 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0327336 |
| PLAC8 | placenta-specific 8 | -0.0326928 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0326549 |
| IER3 | immediate early response 3 | -0.0325453 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0322443 |
| SERINC5 | serine incorporator 5 | -0.0306489 |
| RPL34 | ribosomal protein L34 | -0.0303286 |
| SQSTM1 | sequestosome 1 | -0.0301999 |
| KRT19 | keratin 19, type I | -0.0300747 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0300686 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0299395 |
| SULF2 | sulfatase 2 | -0.0297538 |
| ITGB8 | integrin, beta 8 | -0.0297457 |
| EPCAM | epithelial cell adhesion molecule | -0.0293061 |
| HMGA2 | high mobility group AT-hook 2 | -0.0291422 |
| GNAS | GNAS complex locus | -0.0289951 |
| S100A4 | S100 calcium binding protein A4 | -0.0289085 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0285507 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0281945 |
| EHBP1 | EH domain binding protein 1 | -0.028174 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0279789 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0278663 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0277415 |
| PLSCR1 | phospholipid scramblase 1 | -0.0276891 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.027656 |
| RPL37A | ribosomal protein L37a | -0.0275615 |
| CD2AP | CD2-associated protein | -0.027337 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0268374 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0264458 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0263222 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -0.0261594 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0257526 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0256473 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0253929 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0253033 |
| EXOC4 | exocyst complex component 4 | -0.0252993 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0252818 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0251539 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0251017 |
| RPL11 | ribosomal protein L11 | -0.0249882 |
| ANXA4 | annexin A4 | -0.0249808 |
| MX1 | MX dynamin-like GTPase 1 | -0.0247232 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0246113 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0239629 |
| RPS21 | ribosomal protein S21 | -0.0233817 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0233699 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0233699 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.023338 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0232932 |
| MUC17 | mucin 17, cell surface associated | -0.0231695 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.022907 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.02288 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0228659 |
| RHEB | Ras homolog enriched in brain | -0.0228278 |
| RESF1 | retroelement silencing factor 1 | -0.0227295 |
| ETV6 | ets variant 6 | -0.0226956 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0224735 |
