| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fedratinib (hydrochloride hydrate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fedratinib (hydrochloride hydrate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | 0.278452 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.161464 |
| ASPH | aspartate beta-hydroxylase | 0.143103 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.138856 |
| SDC4 | syndecan 4 | 0.119386 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.106299 |
| TMSB4X | thymosin beta 4, X-linked | 0.101619 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0940153 |
| APP | amyloid beta (A4) precursor protein | 0.093291 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0918785 |
| POTEF | POTE ankyrin domain family, member F | 0.0908039 |
| MT1X | metallothionein 1X | 0.0895072 |
| AHNAK | AHNAK nucleoprotein | 0.0881277 |
| SPAG9 | sperm associated antigen 9 | 0.085241 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0828298 |
| ENO1 | enolase 1, (alpha) | 0.0827556 |
| KRT8 | keratin 8, type II | 0.0815822 |
| PTMA | prothymosin, alpha | 0.0802308 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0748893 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0742831 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0727848 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0717798 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0709328 |
| PCBP2 | poly(rC) binding protein 2 | 0.0688108 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0671592 |
| CANX | calnexin | 0.0661014 |
| PLAU | plasminogen activator, urokinase | 0.0650709 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0641792 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0637999 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0603371 |
| PGK1 | phosphoglycerate kinase 1 | 0.059405 |
| CCNY | cyclin Y | 0.0563701 |
| OGA | O-GlcNAcase | 0.0559993 |
| EZR | ezrin | 0.0559801 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0554383 |
| INSIG1 | insulin induced gene 1 | 0.0551665 |
| TPM3 | tropomyosin 3 | 0.0542726 |
| ANXA2 | annexin A2 | 0.048468 |
| RPLP0 | ribosomal protein, large, P0 | 0.0482404 |
| SFTPA2 | surfactant protein A2 | 0.0473097 |
| LDHA | lactate dehydrogenase A | 0.0471822 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.04465 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0441685 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0436332 |
| CALR | calreticulin | 0.0430196 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0428449 |
| LAMB3 | laminin, beta 3 | 0.0401921 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0401834 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0394136 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0384702 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0383029 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0380207 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0373785 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0370383 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0364922 |
| VIM | vimentin | 0.0364113 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | 0.0362098 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0348343 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0346275 |
| S100A6 | S100 calcium binding protein A6 | 0.0343899 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0343876 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0342203 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0339914 |
| SRP54 | signal recognition particle 54kDa | 0.0337535 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0336711 |
| ANXA1 | annexin A1 | 0.0334556 |
| EMP1 | epithelial membrane protein 1 | 0.0327576 |
| HDLBP | high density lipoprotein binding protein | 0.0325079 |
| PEG10 | paternally expressed 10 | 0.0324093 |
| HLA-C | major histocompatibility complex, class I, C | 0.0317887 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0317441 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0314 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0310088 |
| CCNL1 | cyclin L1 | 0.0309648 |
| DSPP | dentin sialophosphoprotein | 0.0309302 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0304024 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0297804 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0292864 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0291867 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0290942 |
| RPL4 | ribosomal protein L4 | 0.0290705 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0287316 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0284579 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0283994 |
| RLF | rearranged L-myc fusion | 0.0283361 |
| MYO5B | myosin VB | 0.0283278 |
| FNIP1 | folliculin interacting protein 1 | 0.028264 |
| DST | dystonin | 0.0277589 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0277445 |
| C12ORF75 | chromosome 12 open reading frame 75 | 0.0276557 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0275958 |
| HMGB2 | high mobility group box 2 | 0.0270882 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0270284 |
| LASP1 | LIM and SH3 protein 1 | 0.026765 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0267461 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0265146 |
| VMP1 | vacuole membrane protein 1 | 0.0261493 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0255417 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0248452 |
| WDR45B | WD repeat domain 45B | 0.0247515 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.165559 |
| HLA-B | major histocompatibility complex, class I, B | -0.119516 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.105115 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.103921 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0784427 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0720386 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0693546 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0677014 |
| SP100 | SP100 nuclear antigen | -0.0668745 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0597938 |
| APOL1 | apolipoprotein L, 1 | -0.0589234 |
| MX1 | MX dynamin-like GTPase 1 | -0.0579521 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0561874 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0548777 |
| RNF213 | ring finger protein 213 | -0.0506953 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.0504186 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0501415 |
| NDRG1 | N-myc downstream regulated 1 | -0.0489956 |
| RPS29 | ribosomal protein S29 | -0.0485513 |
| MX2 | MX dynamin-like GTPase 2 | -0.0484541 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0479629 |
| S100A10 | S100 calcium binding protein A10 | -0.0478611 |
| PLAT | plasminogen activator, tissue | -0.0477291 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.047375 |
| RPS2 | ribosomal protein S2 | -0.0472999 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0453433 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0446109 |
| PMP22 | peripheral myelin protein 22 | -0.042648 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.04264 |
| RPS23 | ribosomal protein S23 | -0.0426182 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0413537 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0407135 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0406566 |
| LCN2 | lipocalin 2 | -0.0402534 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0396384 |
| HMGA1 | high mobility group AT-hook 1 | -0.0387752 |
| CDCP1 | CUB domain containing protein 1 | -0.0381786 |
| FOSL1 | FOS-like antigen 1 | -0.036646 |
| RPS24 | ribosomal protein S24 | -0.0365279 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0363296 |
| OSMR | oncostatin M receptor | -0.0356721 |
| RPL31 | ribosomal protein L31 | -0.0353905 |
| RPL9 | ribosomal protein L9 | -0.0352604 |
| RPL37A | ribosomal protein L37a | -0.035178 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0346762 |
| RAD51B | RAD51 paralog B | -0.0340518 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0327157 |
| CP | ceruloplasmin (ferroxidase) | -0.0326368 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0318133 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0316889 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0312377 |
| PKM | pyruvate kinase, muscle | -0.0307125 |
| VEGFA | vascular endothelial growth factor A | -0.0300741 |
| MMP7 | matrix metallopeptidase 7 | -0.0300163 |
| HLA-A | major histocompatibility complex, class I, A | -0.0298712 |
| NUMB | numb homolog (Drosophila) | -0.0296955 |
| EFNA5 | ephrin-A5 | -0.0296629 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0295453 |
| C3 | complement component 3 | -0.029394 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0293673 |
| BBX | bobby sox homolog (Drosophila) | -0.029329 |
| EGR1 | early growth response 1 | -0.0292899 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0292781 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0289505 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0286648 |
| KIAA1217 | KIAA1217 | -0.0285941 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0283272 |
| IER3 | immediate early response 3 | -0.0280126 |
| TMC5 | transmembrane channel-like 5 | -0.0275993 |
| BRD2 | bromodomain containing 2 | -0.0274487 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0272157 |
| ADAR | adenosine deaminase, RNA-specific | -0.0271462 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0268425 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0266127 |
| LAP3 | leucine aminopeptidase 3 | -0.0264289 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | -0.0261645 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.026054 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.026006 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.025863 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0257216 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0256705 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0254684 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0253573 |
| RPLP1 | ribosomal protein, large, P1 | -0.0253052 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0249198 |
| RUNX1 | runt-related transcription factor 1 | -0.0248323 |
| RPS17 | ribosomal protein S17 | -0.0247389 |
| RRBP1 | ribosome binding protein 1 | -0.0243889 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0243343 |
| IFI44L | interferon-induced protein 44-like | -0.0242891 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0241513 |
| RPL38 | ribosomal protein L38 | -0.0238844 |
| IFI44 | interferon-induced protein 44 | -0.0238481 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0237344 |
| RIGI | RNA sensor RIG-I | -0.0237124 |
| NABP1 | nucleic acid binding protein 1 | -0.0237 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0235527 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0234978 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0233399 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0232233 |
