| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fedratinib (hydrochloride hydrate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fedratinib (hydrochloride hydrate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.186132 |
| VCL | vinculin | 0.127077 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.111929 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0994856 |
| MEIS2 | Meis homeobox 2 | 0.0928713 |
| LPIN1 | lipin 1 | 0.0877829 |
| DST | dystonin | 0.0815141 |
| MAP1B | microtubule-associated protein 1B | 0.0797777 |
| PLAT | plasminogen activator, tissue | 0.0777249 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0773723 |
| FAM13A | family with sequence similarity 13, member A | 0.0767651 |
| ACTG1 | actin gamma 1 | 0.0733107 |
| FMN1 | formin 1 | 0.0729622 |
| PCBP2 | poly(rC) binding protein 2 | 0.0717672 |
| TLE4 | transducin-like enhancer of split 4 | 0.0639412 |
| HELZ | helicase with zinc finger | 0.0637595 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0576963 |
| CADM1 | cell adhesion molecule 1 | 0.057687 |
| MEF2A | myocyte enhancer factor 2A | 0.0573898 |
| GPC5 | glypican 5 | 0.056543 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0555544 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0543399 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0543226 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0541779 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0539134 |
| NRG1 | neuregulin 1 | 0.053689 |
| APP | amyloid beta (A4) precursor protein | 0.0534498 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0531502 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0519857 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0511336 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0499048 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0497955 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0484521 |
| WDR45B | WD repeat domain 45B | 0.0483237 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0481891 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0468422 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.046469 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0458228 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0456776 |
| NDRG1 | N-myc downstream regulated 1 | 0.0450757 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0450408 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0449893 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0442778 |
| ZNF292 | zinc finger protein 292 | 0.0437739 |
| VMP1 | vacuole membrane protein 1 | 0.0434649 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0433464 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0423706 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0422715 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0422567 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0421296 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0408646 |
| ENO1 | enolase 1, (alpha) | 0.0402653 |
| PRKCA | protein kinase C, alpha | 0.0401487 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0400567 |
| CANX | calnexin | 0.0400484 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0399423 |
| SEPTIN9 | septin 9 | 0.0395951 |
| GOLGA4 | golgin A4 | 0.0391766 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0391244 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0386327 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.038607 |
| DPH6 | diphthamine biosynthesis 6 | 0.0384458 |
| PHF3 | PHD finger protein 3 | 0.0380953 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0379382 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0374025 |
| TPR | translocated promoter region, nuclear basket protein | 0.0370172 |
| TMF1 | TATA element modulatory factor 1 | 0.0362241 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0358537 |
| MYO9A | myosin IXA | 0.0358332 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0355611 |
| CUL3 | cullin 3 | 0.0355373 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0351663 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0349503 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0347076 |
| FNBP1 | formin binding protein 1 | 0.034661 |
| CSNK1D | casein kinase 1, delta | 0.0341682 |
| PRPF3 | pre-mRNA processing factor 3 | 0.0340617 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0339591 |
| YTHDC1 | YTH domain containing 1 | 0.0337864 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0337625 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0337415 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0334912 |
| NBEA | neurobeachin | 0.0329566 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.032887 |
| CYTH1 | cytohesin 1 | 0.0328436 |
| ZNF395 | zinc finger protein 395 | 0.032722 |
| CCNY | cyclin Y | 0.0324546 |
| ENAH | enabled homolog (Drosophila) | 0.0322938 |
| ARRDC3 | arrestin domain containing 3 | 0.0322844 |
| MSI2 | musashi RNA-binding protein 2 | 0.0320392 |
| GPC6 | glypican 6 | 0.0320203 |
| MBTD1 | mbt domain containing 1 | 0.0319659 |
| CLTC | clathrin, heavy chain (Hc) | 0.0319488 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0318889 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0317518 |
| ZNF638 | zinc finger protein 638 | 0.031638 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0313958 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0312812 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0312642 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0312588 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.195271 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.120551 |
| RPL35A | ribosomal protein L35a | -0.0973536 |
| RPLP1 | ribosomal protein, large, P1 | -0.0921704 |
| RPL23 | ribosomal protein L23 | -0.0892162 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.084071 |
| RPS6 | ribosomal protein S6 | -0.0830908 |
| RPS24 | ribosomal protein S24 | -0.0807544 |
| RPL34 | ribosomal protein L34 | -0.0802227 |
| RPL38 | ribosomal protein L38 | -0.0704296 |
| RPS19 | ribosomal protein S19 | -0.0634175 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0613363 |
| TMSB10 | thymosin beta 10 | -0.0569897 |
| VIM | vimentin | -0.055586 |
| RPL31 | ribosomal protein L31 | -0.0547152 |
| RPL27 | ribosomal protein L27 | -0.0511738 |
| RPL19 | ribosomal protein L19 | -0.0498693 |
| FTL | ferritin, light polypeptide | -0.0492198 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.047135 |
| RPL32 | ribosomal protein L32 | -0.0467456 |
| RPL37A | ribosomal protein L37a | -0.0444911 |
| RPL26 | ribosomal protein L26 | -0.0428909 |
| RPS3 | ribosomal protein S3 | -0.0419899 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0419439 |
| RPL36 | ribosomal protein L36 | -0.0380385 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0374214 |
| PTMA | prothymosin, alpha | -0.0373344 |
| S100A9 | S100 calcium binding protein A9 | -0.0361841 |
| RPS20 | ribosomal protein S20 | -0.0358971 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0354908 |
| RPS5 | ribosomal protein S5 | -0.0346098 |
| RPS23 | ribosomal protein S23 | -0.0331527 |
| TBX2 | T-box 2 | -0.0330396 |
| RPL11 | ribosomal protein L11 | -0.0323459 |
| FAM162A | family with sequence similarity 162, member A | -0.0320072 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0311467 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0309178 |
| RPS29 | ribosomal protein S29 | -0.0301596 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0291416 |
| RPLP2 | ribosomal protein, large, P2 | -0.0290792 |
| RPS8 | ribosomal protein S8 | -0.0290237 |
| RPS11 | ribosomal protein S11 | -0.0284962 |
| RPL30 | ribosomal protein L30 | -0.0278113 |
| RPS15 | ribosomal protein S15 | -0.027191 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.027089 |
| HMGB1 | high mobility group box 1 | -0.026853 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0267329 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0265265 |
| RPL36A | ribosomal protein L36a | -0.0259825 |
| RPS21 | ribosomal protein S21 | -0.0258544 |
| RPS14 | ribosomal protein S14 | -0.0257512 |
| RPL12 | ribosomal protein L12 | -0.0248452 |
| RPS13 | ribosomal protein S13 | -0.0247872 |
| RPL9 | ribosomal protein L9 | -0.024748 |
| COL1A1 | collagen, type I, alpha 1 | -0.0245881 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0245521 |
| IER3 | immediate early response 3 | -0.0238611 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.023842 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0236136 |
| RPL6 | ribosomal protein L6 | -0.0235139 |
| RPL8 | ribosomal protein L8 | -0.023257 |
| RPL5 | ribosomal protein L5 | -0.0231107 |
| HMGA1 | high mobility group AT-hook 1 | -0.022849 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0226092 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0225275 |
| RPL35 | ribosomal protein L35 | -0.0224078 |
| YBX1 | Y box binding protein 1 | -0.0223455 |
| RPS25 | ribosomal protein S25 | -0.022243 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0220745 |
| KIF21A | kinesin family member 21A | -0.0218133 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0217537 |
| RPLP0 | ribosomal protein, large, P0 | -0.0216878 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0216848 |
| RPS2 | ribosomal protein S2 | -0.0216652 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0215966 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0215419 |
| GATA3 | GATA binding protein 3 | -0.0214053 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0213983 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -0.0212705 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0207984 |
| RPL7 | ribosomal protein L7 | -0.0207026 |
| LMNA | lamin A/C | -0.0206772 |
| RPL37 | ribosomal protein L37 | -0.0205625 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.0205123 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0204481 |
| SSH2 | slingshot protein phosphatase 2 | -0.0204185 |
| ZNF804A | zinc finger protein 804A | -0.0203632 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0202917 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0201278 |
| RNF145 | ring finger protein 145 | -0.0199827 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0198568 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.019743 |
| RPS17 | ribosomal protein S17 | -0.0195339 |
| RPS12 | ribosomal protein S12 | -0.0192651 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0192273 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0191924 |
| GNAS | GNAS complex locus | -0.0191822 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0191428 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0190775 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0190183 |
