| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fedratinib (hydrochloride hydrate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fedratinib (hydrochloride hydrate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.120708 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.116366 |
| STC1 | stanniocalcin 1 | 0.114684 |
| PGK1 | phosphoglycerate kinase 1 | 0.104501 |
| MT2A | metallothionein 2A | 0.103775 |
| GOLGA4 | golgin A4 | 0.102563 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0877395 |
| ZNF292 | zinc finger protein 292 | 0.0839589 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.067806 |
| POTEF | POTE ankyrin domain family, member F | 0.0612111 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0605162 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0565885 |
| LDHA | lactate dehydrogenase A | 0.0563594 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0530497 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0523776 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0500551 |
| PKM | pyruvate kinase, muscle | 0.0484088 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0481401 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0455869 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.045413 |
| NDRG1 | N-myc downstream regulated 1 | 0.0452938 |
| SDC4 | syndecan 4 | 0.0450366 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0442504 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0436027 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0432988 |
| XPO1 | exportin 1 | 0.0430893 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0422538 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.042131 |
| OGA | O-GlcNAcase | 0.0419124 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0414611 |
| RBM39 | RNA binding motif protein 39 | 0.0412257 |
| ANLN | anillin, actin binding protein | 0.0406055 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0403714 |
| ENO1 | enolase 1, (alpha) | 0.0398614 |
| CD109 | CD109 molecule | 0.0391907 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0390637 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0386003 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0384607 |
| HMGB2 | high mobility group box 2 | 0.0378646 |
| TPM3 | tropomyosin 3 | 0.0376833 |
| CENPF | centromere protein F, 350/400kDa | 0.0375659 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0371551 |
| RTN4 | reticulon 4 | 0.0369849 |
| TPX2 | TPX2, microtubule-associated | 0.0368002 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0367007 |
| FAM162A | family with sequence similarity 162, member A | 0.0364837 |
| SRP54 | signal recognition particle 54kDa | 0.0361921 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.036062 |
| SETD5 | SET domain containing 5 | 0.0360059 |
| MSN | moesin | 0.0351017 |
| TMF1 | TATA element modulatory factor 1 | 0.0349252 |
| SEPTIN7 | septin 7 | 0.0345938 |
| PCBP2 | poly(rC) binding protein 2 | 0.0337382 |
| COPA | coatomer protein complex, subunit alpha | 0.0336897 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0335744 |
| NUP58 | nucleoporin 58 | 0.0335166 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0332187 |
| RPS6 | ribosomal protein S6 | 0.0323993 |
| DSTN | destrin (actin depolymerizing factor) | 0.0322915 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0319708 |
| HELZ | helicase with zinc finger | 0.0318282 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0314012 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0313249 |
| RLF | rearranged L-myc fusion | 0.0309989 |
| FAM13A | family with sequence similarity 13, member A | 0.030946 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0309298 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0308825 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0308225 |
| TFG | TRK-fused gene | 0.0307871 |
| INSIG2 | insulin induced gene 2 | 0.0304827 |
| VEGFA | vascular endothelial growth factor A | 0.0304043 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0302282 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0301932 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0300866 |
| RNF24 | ring finger protein 24 | 0.0299974 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0295708 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0294838 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.0293157 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0289426 |
| CALU | calumenin | 0.0289383 |
| PTMA | prothymosin, alpha | 0.0289141 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0286868 |
| NOP58 | NOP58 ribonucleoprotein | 0.0286227 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0283598 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0281765 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0281303 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0280896 |
| SUCO | SUN domain containing ossification factor | 0.0279942 |
| SPAG9 | sperm associated antigen 9 | 0.0279592 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0279177 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0276698 |
| USP37 | ubiquitin specific peptidase 37 | 0.0274649 |
| CALR | calreticulin | 0.0269704 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.026952 |
| ARRDC3 | arrestin domain containing 3 | 0.0269492 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0269235 |
| ZNF148 | zinc finger protein 148 | 0.0268143 |
| CCNL1 | cyclin L1 | 0.0268096 |
| MKI67 | marker of proliferation Ki-67 | 0.0267293 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.026619 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | -0.139965 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.136728 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.123888 |
| COL1A1 | collagen, type I, alpha 1 | -0.105434 |
| FRMD4A | FERM domain containing 4A | -0.10485 |
| HLA-B | major histocompatibility complex, class I, B | -0.0896161 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0883697 |
| NAV1 | neuron navigator 1 | -0.0816519 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0811847 |
| SP100 | SP100 nuclear antigen | -0.0800178 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0776521 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0746438 |
| GLIS3 | GLIS family zinc finger 3 | -0.0684741 |
| LOXL2 | lysyl oxidase-like 2 | -0.0604917 |
| TMEM178B | transmembrane protein 178B | -0.0597684 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.058712 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0569948 |
| COL1A2 | collagen, type I, alpha 2 | -0.0565294 |
| INHBA | inhibin, beta A | -0.0556583 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0519568 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0519456 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.050258 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0494646 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0493207 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0491069 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0489648 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0484763 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0464112 |
| HDAC9 | histone deacetylase 9 | -0.0461094 |
| COL5A1 | collagen, type V, alpha 1 | -0.0451159 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.04429 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.044145 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0440122 |
| CADM1 | cell adhesion molecule 1 | -0.0437371 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0434741 |
| PCBP3 | poly(rC) binding protein 3 | -0.0431645 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0428337 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0424261 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0417555 |
| IER3 | immediate early response 3 | -0.0413291 |
| EGFR | epidermal growth factor receptor | -0.0409821 |
| RAI14 | retinoic acid induced 14 | -0.0409799 |
| HPCAL1 | hippocalcin-like 1 | -0.0408741 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0407747 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0402321 |
| TNNC1 | troponin C type 1 (slow) | -0.0401611 |
| PLSCR1 | phospholipid scramblase 1 | -0.0394875 |
| RIGI | RNA sensor RIG-I | -0.0394375 |
| XAF1 | XIAP associated factor 1 | -0.0386995 |
| FHIT | fragile histidine triad | -0.0378638 |
| TNS3 | tensin 3 | -0.0368727 |
| IL1B | interleukin 1, beta | -0.0367256 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0358013 |
| HLA-A | major histocompatibility complex, class I, A | -0.0357224 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0357179 |
| MTSS1 | metastasis suppressor 1 | -0.0356977 |
| HLA-C | major histocompatibility complex, class I, C | -0.0355152 |
| HMGA2 | high mobility group AT-hook 2 | -0.0354588 |
| EGR1 | early growth response 1 | -0.0353413 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0352644 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0352041 |
| DST | dystonin | -0.034886 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0330855 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0329068 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0323299 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.032168 |
| INTS6 | integrator complex subunit 6 | -0.0320255 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0319335 |
| ATXN1 | ataxin 1 | -0.0318931 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0318687 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0317359 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0316856 |
| HLA-E | major histocompatibility complex, class I, E | -0.0314995 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0313437 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0297836 |
| COL5A3 | collagen, type V, alpha 3 | -0.0294572 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0290704 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0284312 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0283107 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0278734 |
| CCDC138 | coiled-coil domain containing 138 | -0.0275289 |
| RNF213 | ring finger protein 213 | -0.0271644 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) | -0.0270619 |
| MMP12 | matrix metallopeptidase 12 | -0.0269389 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0267096 |
| FBN1 | fibrillin 1 | -0.0265638 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0265313 |
| ASPH | aspartate beta-hydroxylase | -0.0264712 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0259841 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0259677 |
| SYNDIG1 | synapse differentiation inducing 1 | -0.0259023 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0256377 |
| NABP1 | nucleic acid binding protein 1 | -0.0256332 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0253143 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0253077 |
| VCL | vinculin | -0.025222 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0251199 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0250546 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0250314 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0249765 |
