| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fedratinib (hydrochloride hydrate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fedratinib (hydrochloride hydrate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | 0.123898 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.121237 |
| VCL | vinculin | 0.0984755 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.087626 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0836939 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0829616 |
| TMSB4X | thymosin beta 4, X-linked | 0.0739898 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0679184 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.066874 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0657291 |
| PCBP2 | poly(rC) binding protein 2 | 0.0637386 |
| GOLGA4 | golgin A4 | 0.0615762 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0586319 |
| PDGFC | platelet derived growth factor C | 0.0571691 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0544693 |
| USP47 | ubiquitin specific peptidase 47 | 0.0526068 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0510231 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0508694 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0493636 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0485462 |
| CCNL1 | cyclin L1 | 0.0483921 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0483608 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0476443 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0473602 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0466374 |
| QKI | QKI, KH domain containing, RNA binding | 0.0464217 |
| FAM13A | family with sequence similarity 13, member A | 0.0460862 |
| CENPF | centromere protein F, 350/400kDa | 0.0452723 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0446948 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0446816 |
| POTEF | POTE ankyrin domain family, member F | 0.0446377 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0445562 |
| CD47 | CD47 molecule | 0.0441792 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0438408 |
| MYOF | myoferlin | 0.0438301 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0438162 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0435652 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0427063 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0425513 |
| TMEM65 | transmembrane protein 65 | 0.042427 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0423701 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0423398 |
| SMNDC1 | survival motor neuron domain containing 1 | 0.0421879 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0419568 |
| TJP1 | tight junction protein 1 | 0.0415261 |
| WDR45B | WD repeat domain 45B | 0.039801 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0394072 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0393283 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0385366 |
| ZNF292 | zinc finger protein 292 | 0.0382873 |
| PGK1 | phosphoglycerate kinase 1 | 0.0378602 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0378115 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0374089 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0373641 |
| ECT2 | epithelial cell transforming 2 | 0.0373634 |
| ANXA1 | annexin A1 | 0.0365634 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0364009 |
| HELZ | helicase with zinc finger | 0.0360848 |
| FNIP1 | folliculin interacting protein 1 | 0.0359985 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0351688 |
| SET | SET nuclear proto-oncogene | 0.034981 |
| DSTN | destrin (actin depolymerizing factor) | 0.0348665 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0347439 |
| GOLGA2 | golgin A2 | 0.0341696 |
| NBAS | neuroblastoma amplified sequence | 0.0340723 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0338305 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0335041 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0334629 |
| PTK2 | protein tyrosine kinase 2 | 0.0333009 |
| XPO1 | exportin 1 | 0.0332973 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0326862 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0324874 |
| NUP58 | nucleoporin 58 | 0.0322868 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0321272 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0318687 |
| ARRDC3 | arrestin domain containing 3 | 0.0314957 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0312768 |
| RBM25 | RNA binding motif protein 25 | 0.0307304 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0307236 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.030623 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0304151 |
| YTHDC1 | YTH domain containing 1 | 0.0303825 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0303052 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0300938 |
| SBF2 | SET binding factor 2 | 0.030038 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0297699 |
| JMJD1C | jumonji domain containing 1C | 0.0297328 |
| ANXA3 | annexin A3 | 0.0296122 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0294015 |
| ASPH | aspartate beta-hydroxylase | 0.0293866 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0293396 |
| PRELID2 | PRELI domain containing 2 | 0.0289181 |
| CANX | calnexin | 0.0286392 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0285295 |
| TMF1 | TATA element modulatory factor 1 | 0.0284833 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0283779 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0282009 |
| COPA | coatomer protein complex, subunit alpha | 0.0281729 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0281619 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0275289 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.252232 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.190616 |
| PKM | pyruvate kinase, muscle | -0.142564 |
| AHNAK | AHNAK nucleoprotein | -0.141921 |
| PTMA | prothymosin, alpha | -0.123374 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.116234 |
| RPS27A | ribosomal protein S27a | -0.0851544 |
| RPS6 | ribosomal protein S6 | -0.0808567 |
| UBC | ubiquitin C | -0.0780824 |
| RPLP1 | ribosomal protein, large, P1 | -0.0750001 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0696274 |
| S100A6 | S100 calcium binding protein A6 | -0.0669119 |
| RPS19 | ribosomal protein S19 | -0.0667474 |
| RPL23 | ribosomal protein L23 | -0.0572343 |
| RPS8 | ribosomal protein S8 | -0.0561648 |
| RPL12 | ribosomal protein L12 | -0.0560361 |
| RPL34 | ribosomal protein L34 | -0.0552342 |
| TMSB10 | thymosin beta 10 | -0.0549005 |
| BMP10 | bone morphogenetic protein 10 | -0.0539334 |
| RPS23 | ribosomal protein S23 | -0.0539306 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0530847 |
| EGFR | epidermal growth factor receptor | -0.0524587 |
| S100A10 | S100 calcium binding protein A10 | -0.0522463 |
| RPL31 | ribosomal protein L31 | -0.0503941 |
| RPS24 | ribosomal protein S24 | -0.0499336 |
| S100A9 | S100 calcium binding protein A9 | -0.0494521 |
| RPLP2 | ribosomal protein, large, P2 | -0.0491024 |
| RPL9 | ribosomal protein L9 | -0.048308 |
| RPS25 | ribosomal protein S25 | -0.0452692 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0450832 |
| CCND1 | cyclin D1 | -0.0443903 |
| RPL19 | ribosomal protein L19 | -0.0432537 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0431645 |
| FOXP1 | forkhead box P1 | -0.0413059 |
| TXNRD1 | thioredoxin reductase 1 | -0.038594 |
| RPS21 | ribosomal protein S21 | -0.0376588 |
| RPL37A | ribosomal protein L37a | -0.0375013 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0371991 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0370942 |
| RPS13 | ribosomal protein S13 | -0.0365988 |
| OSMR | oncostatin M receptor | -0.035856 |
| RPL36 | ribosomal protein L36 | -0.0357509 |
| RPL28 | ribosomal protein L28 | -0.0350081 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0343983 |
| RPS5 | ribosomal protein S5 | -0.0342421 |
| GNAS | GNAS complex locus | -0.0337762 |
| RIGI | RNA sensor RIG-I | -0.0334127 |
| S100A4 | S100 calcium binding protein A4 | -0.0322649 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0321815 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0321272 |
| RPL26 | ribosomal protein L26 | -0.0319439 |
| RPL8 | ribosomal protein L8 | -0.0310059 |
| RPL36A | ribosomal protein L36a | -0.0309983 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.030422 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0301096 |
| RPS12 | ribosomal protein S12 | -0.0298321 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0294131 |
| RPL5 | ribosomal protein L5 | -0.0290862 |
| RPL11 | ribosomal protein L11 | -0.0290171 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.028812 |
| RPS29 | ribosomal protein S29 | -0.0284565 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0278775 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0275903 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0275579 |
| RPL32 | ribosomal protein L32 | -0.0275357 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0274328 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0274265 |
| FLNB | filamin B, beta | -0.027211 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0269376 |
| SP100 | SP100 nuclear antigen | -0.0269362 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0268915 |
| RACK1 | receptor for activated C kinase 1 | -0.0266795 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0266184 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0265491 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0265094 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.0263398 |
| NPR2 | natriuretic peptide receptor 2 | -0.0262726 |
| RPL35A | ribosomal protein L35a | -0.0259504 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.02582 |
| RPL18 | ribosomal protein L18 | -0.0257 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0255149 |
| RPL14 | ribosomal protein L14 | -0.0250166 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0249982 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0242645 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0240013 |
| RPS10 | ribosomal protein S10 | -0.0238946 |
| RPL6 | ribosomal protein L6 | -0.0236986 |
| BCOR | BCL6 corepressor | -0.0234638 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0231102 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.022956 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0229236 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0227343 |
| RPL35 | ribosomal protein L35 | -0.0224854 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0223765 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0221907 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.02211 |
| ATF4 | activating transcription factor 4 | -0.0220111 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0220058 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0219357 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0217148 |
