| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fedratinib (hydrochloride hydrate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fedratinib (hydrochloride hydrate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.165153 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.112881 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.099802 |
| OGA | O-GlcNAcase | 0.0937585 |
| PGK1 | phosphoglycerate kinase 1 | 0.0786081 |
| ARRDC3 | arrestin domain containing 3 | 0.0759793 |
| FN1 | fibronectin 1 | 0.0736354 |
| SFTPA2 | surfactant protein A2 | 0.0687731 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0684615 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0680174 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0668177 |
| SDC4 | syndecan 4 | 0.0652142 |
| LDHA | lactate dehydrogenase A | 0.0642712 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0628197 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.060443 |
| SPAG9 | sperm associated antigen 9 | 0.0598425 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0585062 |
| ANLN | anillin, actin binding protein | 0.0564704 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0560648 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0558709 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0557957 |
| FNIP1 | folliculin interacting protein 1 | 0.0556919 |
| CANX | calnexin | 0.055169 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.052571 |
| NDRG1 | N-myc downstream regulated 1 | 0.0514161 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0509441 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.05029 |
| JMJD1C | jumonji domain containing 1C | 0.0498115 |
| NAV2 | neuron navigator 2 | 0.0489642 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0471785 |
| STC1 | stanniocalcin 1 | 0.0467677 |
| MKI67 | marker of proliferation Ki-67 | 0.0466862 |
| CENPF | centromere protein F, 350/400kDa | 0.0454089 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0448908 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0434876 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0432272 |
| TMSB4X | thymosin beta 4, X-linked | 0.0427598 |
| ACTG1 | actin gamma 1 | 0.0426307 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0426212 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0419501 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0409294 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0406661 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0403213 |
| AHNAK | AHNAK nucleoprotein | 0.0395757 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0395309 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0394214 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0387104 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0383428 |
| PCBP2 | poly(rC) binding protein 2 | 0.038239 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.037366 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0365412 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.036503 |
| APP | amyloid beta (A4) precursor protein | 0.036261 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0354438 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0346282 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0337872 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0337063 |
| CDK19 | cyclin-dependent kinase 19 | 0.0335884 |
| DIAPH3 | diaphanous-related formin 3 | 0.033312 |
| GOLGA4 | golgin A4 | 0.0329756 |
| ZNF292 | zinc finger protein 292 | 0.0325838 |
| YTHDC1 | YTH domain containing 1 | 0.0324633 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0313405 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0305598 |
| MYOF | myoferlin | 0.0303114 |
| SERINC3 | serine incorporator 3 | 0.030143 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0299468 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.029751 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0295951 |
| ATP13A3 | ATPase type 13A3 | 0.0293256 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0290836 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0289959 |
| RBM39 | RNA binding motif protein 39 | 0.0289426 |
| AFDN | afadin, adherens junction formation factor | 0.0288536 |
| PHF3 | PHD finger protein 3 | 0.0286993 |
| ENO1 | enolase 1, (alpha) | 0.028175 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0276899 |
| HDLBP | high density lipoprotein binding protein | 0.0275316 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0273877 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0273427 |
| INSIG1 | insulin induced gene 1 | 0.0272452 |
| CACUL1 | CDK2-associated, cullin domain 1 | 0.0271858 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0269703 |
| FLNB | filamin B, beta | 0.0265939 |
| TPX2 | TPX2, microtubule-associated | 0.0264025 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0259844 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0259312 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0254097 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0253534 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0253282 |
| CLTC | clathrin, heavy chain (Hc) | 0.0252657 |
| ARFGEF3 | ARFGEF family member 3 | 0.0251799 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0251583 |
| ADM | adrenomedullin | 0.0250827 |
| COPA | coatomer protein complex, subunit alpha | 0.024868 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0245935 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0245753 |
| THOC2 | THO complex 2 | 0.0245629 |
| PTMA | prothymosin, alpha | 0.0242606 |
| HELZ | helicase with zinc finger | 0.0240406 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.106281 |
| TMSB10 | thymosin beta 10 | -0.0931185 |
| IER3 | immediate early response 3 | -0.0755316 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.075305 |
| GLIS3 | GLIS family zinc finger 3 | -0.0741166 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0672399 |
| MT2A | metallothionein 2A | -0.0583975 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0570941 |
| HLA-B | major histocompatibility complex, class I, B | -0.0512619 |
| RPLP2 | ribosomal protein, large, P2 | -0.0509314 |
| RPS6 | ribosomal protein S6 | -0.0508116 |
| RPL37A | ribosomal protein L37a | -0.04909 |
| RPS19 | ribosomal protein S19 | -0.0471781 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0464607 |
| CDH13 | cadherin 13 | -0.0458106 |
| TPM1 | tropomyosin 1 (alpha) | -0.0429486 |
| FTL | ferritin, light polypeptide | -0.0421924 |
| RPLP1 | ribosomal protein, large, P1 | -0.0415943 |
| NAV1 | neuron navigator 1 | -0.0408619 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0398757 |
| HMGA2 | high mobility group AT-hook 2 | -0.03987 |
| RPL35A | ribosomal protein L35a | -0.0391282 |
| RPS12 | ribosomal protein S12 | -0.038788 |
| RIGI | RNA sensor RIG-I | -0.0375995 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0374963 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0368279 |
| TMEM132D | transmembrane protein 132D | -0.0366022 |
| RPL9 | ribosomal protein L9 | -0.036219 |
| RPS23 | ribosomal protein S23 | -0.0360626 |
| RPL35 | ribosomal protein L35 | -0.0348377 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0342616 |
| EGR1 | early growth response 1 | -0.0330636 |
| RPL36 | ribosomal protein L36 | -0.0324827 |
| RPS24 | ribosomal protein S24 | -0.0324036 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0323635 |
| VIM | vimentin | -0.0312652 |
| DIAPH2 | diaphanous-related formin 2 | -0.0296318 |
| RPS3 | ribosomal protein S3 | -0.0291644 |
| RPS14 | ribosomal protein S14 | -0.0289011 |
| RPS21 | ribosomal protein S21 | -0.0284685 |
| RPL19 | ribosomal protein L19 | -0.0282501 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.027831 |
| RPL23 | ribosomal protein L23 | -0.0277172 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0273481 |
| HMGA1 | high mobility group AT-hook 1 | -0.0271978 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0271943 |
| SP100 | SP100 nuclear antigen | -0.0268705 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0268698 |
| RPS25 | ribosomal protein S25 | -0.0268291 |
| RPL28 | ribosomal protein L28 | -0.026698 |
| GPC6 | glypican 6 | -0.0265967 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0263244 |
| S100A9 | S100 calcium binding protein A9 | -0.0253361 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0250447 |
| RPL12 | ribosomal protein L12 | -0.0238899 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0236713 |
| TNS3 | tensin 3 | -0.0236073 |
| RPS29 | ribosomal protein S29 | -0.0234178 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.023099 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.022097 |
| PMP22 | peripheral myelin protein 22 | -0.0220781 |
| RPS8 | ribosomal protein S8 | -0.0219391 |
| PLSCR1 | phospholipid scramblase 1 | -0.0218622 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.02184 |
| RPL36A | ribosomal protein L36a | -0.021817 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0217215 |
| HLA-A | major histocompatibility complex, class I, A | -0.021242 |
| RNF213 | ring finger protein 213 | -0.0210556 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0210061 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0208684 |
| TAPBP | TAP binding protein (tapasin) | -0.0205102 |
| RPS10 | ribosomal protein S10 | -0.0203848 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0201637 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0201119 |
| EGFR | epidermal growth factor receptor | -0.0200582 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0198802 |
| RPL30 | ribosomal protein L30 | -0.0198173 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0197273 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0196775 |
| PFN1 | profilin 1 | -0.0194282 |
| RPS13 | ribosomal protein S13 | -0.0193456 |
| RPS27 | ribosomal protein S27 | -0.0191775 |
| RPS20 | ribosomal protein S20 | -0.0189977 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0186308 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0186249 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0185926 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0184756 |
| RPL26 | ribosomal protein L26 | -0.0183667 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0182008 |
| SRGN | serglycin | -0.0181991 |
| C3 | complement component 3 | -0.0181029 |
| BICC1 | BicC family RNA binding protein 1 | -0.0180023 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | -0.017944 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0178394 |
| WFDC10B | WAP four-disulfide core domain 10B | -0.01774 |
| XAF1 | XIAP associated factor 1 | -0.0176333 |
| RPL34 | ribosomal protein L34 | -0.0175989 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0174157 |
| EXOC4 | exocyst complex component 4 | -0.0172976 |
| RPL37 | ribosomal protein L37 | -0.0171217 |
