| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fedratinib (hydrochloride hydrate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fedratinib (hydrochloride hydrate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0624989 |
| SDC4 | syndecan 4 | 0.0620197 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0606244 |
| PTMA | prothymosin, alpha | 0.0541722 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0523257 |
| ACTG1 | actin gamma 1 | 0.0476475 |
| GOLGA4 | golgin A4 | 0.0471969 |
| CCNL1 | cyclin L1 | 0.0428344 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0381978 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0371093 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0362632 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0345614 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.034108 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0331591 |
| DSPP | dentin sialophosphoprotein | 0.0327512 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0319685 |
| KRT8 | keratin 8, type II | 0.0317888 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0315564 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0304471 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0270291 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.026441 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.026407 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0237016 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0233766 |
| SPAG9 | sperm associated antigen 9 | 0.023309 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0230402 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0228562 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0224355 |
| RPS6 | ribosomal protein S6 | 0.0223731 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0221338 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0216258 |
| ANXA1 | annexin A1 | 0.0214828 |
| FNBP1L | formin binding protein 1-like | 0.0213576 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0213466 |
| KRT18 | keratin 18, type I | 0.0210979 |
| GOLGA2 | golgin A2 | 0.0205011 |
| RPL35A | ribosomal protein L35a | 0.0199116 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0193867 |
| TMF1 | TATA element modulatory factor 1 | 0.019379 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0193239 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0187153 |
| ARRDC3 | arrestin domain containing 3 | 0.0186472 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0184591 |
| RAB18 | RAB18, member RAS oncogene family | 0.0183824 |
| HELZ | helicase with zinc finger | 0.0183583 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0183516 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0183417 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0183387 |
| TPM3 | tropomyosin 3 | 0.0181679 |
| INSIG1 | insulin induced gene 1 | 0.017647 |
| USP3 | ubiquitin specific peptidase 3 | 0.0175328 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0174003 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0173411 |
| RBM39 | RNA binding motif protein 39 | 0.0171751 |
| B2M | beta-2-microglobulin | 0.0170181 |
| HMGB2 | high mobility group box 2 | 0.0165042 |
| TUFT1 | tuftelin 1 | 0.0164867 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0163891 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0162679 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0161608 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 | 0.0161425 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | 0.0160619 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0160189 |
| FBXO11 | F-box protein 11 | 0.0159201 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0158726 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0158391 |
| POTEF | POTE ankyrin domain family, member F | 0.0157663 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0157381 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.015593 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.015433 |
| KRT20 | keratin 20, type I | 0.0153369 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0151905 |
| SRP54 | signal recognition particle 54kDa | 0.0151682 |
| TPR | translocated promoter region, nuclear basket protein | 0.0150816 |
| SUCO | SUN domain containing ossification factor | 0.0149648 |
| MXD1 | MAX dimerization protein 1 | 0.0149453 |
| CDA | cytidine deaminase | 0.0149253 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0148726 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.014789 |
| RTN3 | reticulon 3 | 0.0147124 |
| RLF | rearranged L-myc fusion | 0.0146907 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0145644 |
| MTMR3 | myotubularin related protein 3 | 0.0142898 |
| ARF1 | ADP-ribosylation factor 1 | 0.0142489 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0142223 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0141048 |
| RYK | receptor-like tyrosine kinase | 0.014036 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0140305 |
| RAB14 | RAB14, member RAS oncogene family | 0.0139212 |
| RIOK3 | RIO kinase 3 | 0.0139057 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0138558 |
| RBM5 | RNA binding motif protein 5 | 0.0138091 |
| GDF15 | growth differentiation factor 15 | 0.0138086 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.013733 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0136958 |
| MORF4L1 | mortality factor 4 like 1 | 0.0136701 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0136366 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0136359 |
| CASC3 | cancer susceptibility candidate 3 | 0.0136263 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0136183 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.208138 |
| UBC | ubiquitin C | -0.179341 |
| RPS27A | ribosomal protein S27a | -0.0906975 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0898781 |
| BCL2L1 | BCL2-like 1 | -0.0747457 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0657491 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0628822 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0572845 |
| AHNAK | AHNAK nucleoprotein | -0.0554719 |
| PERP | PERP, TP53 apoptosis effector | -0.0542161 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0503036 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0502834 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0501454 |
| EPCAM | epithelial cell adhesion molecule | -0.0487603 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.045567 |
| PKM | pyruvate kinase, muscle | -0.0451851 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0450375 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0439111 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0429463 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0418588 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0415937 |
| S100A10 | S100 calcium binding protein A10 | -0.0408548 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0407509 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0403876 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0402244 |
| SP100 | SP100 nuclear antigen | -0.0399649 |
| RPS24 | ribosomal protein S24 | -0.039651 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0381174 |
| RPL31 | ribosomal protein L31 | -0.0380998 |
| MX2 | MX dynamin-like GTPase 2 | -0.0380657 |
| PLSCR1 | phospholipid scramblase 1 | -0.0374137 |
| CCND1 | cyclin D1 | -0.0373598 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0369667 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0369194 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0366916 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0364288 |
| NEBL | nebulette | -0.0352334 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0348395 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0346528 |
| FLNA | filamin A, alpha | -0.0344574 |
| RPS21 | ribosomal protein S21 | -0.0340139 |
| RPS5 | ribosomal protein S5 | -0.0338355 |
| RPL23 | ribosomal protein L23 | -0.0337415 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0325893 |
| EXOC4 | exocyst complex component 4 | -0.0324995 |
| FAT1 | FAT atypical cadherin 1 | -0.0324067 |
| MED13L | mediator complex subunit 13-like | -0.0323129 |
| FTL | ferritin, light polypeptide | -0.03229 |
| TXNIP | thioredoxin interacting protein | -0.0322084 |
| ANXA2 | annexin A2 | -0.032137 |
| RIGI | RNA sensor RIG-I | -0.0319861 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0318703 |
| VMP1 | vacuole membrane protein 1 | -0.0311907 |
| PRELID2 | PRELI domain containing 2 | -0.0308848 |
| TMEM123 | transmembrane protein 123 | -0.0305686 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.030189 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0298149 |
| ETV6 | ets variant 6 | -0.0297497 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0293104 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.029112 |
| JMJD1C | jumonji domain containing 1C | -0.0289473 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0288239 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0287737 |
| EGR1 | early growth response 1 | -0.0285691 |
| RNF43 | ring finger protein 43 | -0.0284311 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0280514 |
| CADPS | Ca++-dependent secretion activator | -0.0278068 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0276867 |
| RNF213 | ring finger protein 213 | -0.0276815 |
| IER3 | immediate early response 3 | -0.0273151 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0272232 |
| H1-0 | H1.0 linker histone | -0.0266496 |
| CST3 | cystatin C | -0.026508 |
| SMYD3 | SET and MYND domain containing 3 | -0.0263994 |
| ACTN4 | actinin, alpha 4 | -0.0262698 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0261265 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0260728 |
| BBX | bobby sox homolog (Drosophila) | -0.0257767 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0257697 |
| EHBP1 | EH domain binding protein 1 | -0.0256075 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.025495 |
| RPS11 | ribosomal protein S11 | -0.0252717 |
| JUN | jun proto-oncogene | -0.0249485 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.024888 |
| RPS15 | ribosomal protein S15 | -0.0247137 |
| NRP1 | neuropilin 1 | -0.0246927 |
| ITGA6 | integrin, alpha 6 | -0.0246691 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.024639 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0245946 |
| DIAPH2 | diaphanous-related formin 2 | -0.0245324 |
| RPL12 | ribosomal protein L12 | -0.0244962 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.024475 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0244177 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0243486 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0242557 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0237782 |
| VCL | vinculin | -0.0237292 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0236991 |
| RPL28 | ribosomal protein L28 | -0.023599 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0235779 |
