| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fedratinib (hydrochloride hydrate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fedratinib (hydrochloride hydrate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.194307 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.139785 |
| ANXA1 | annexin A1 | 0.138445 |
| LMO7 | LIM domain 7 | 0.128569 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.121154 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.103846 |
| LDHA | lactate dehydrogenase A | 0.0986944 |
| TXNRD1 | thioredoxin reductase 1 | 0.0800596 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0797764 |
| GOLGA4 | golgin A4 | 0.0709857 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0697122 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0692422 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0657451 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0641745 |
| ACTG1 | actin gamma 1 | 0.0637696 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0628899 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0622345 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0597687 |
| TOP1 | topoisomerase (DNA) I | 0.0591536 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0557298 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0556412 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0546805 |
| DSPP | dentin sialophosphoprotein | 0.0542584 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.052226 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0513599 |
| CLTC | clathrin, heavy chain (Hc) | 0.051126 |
| FAT1 | FAT atypical cadherin 1 | 0.05047 |
| SDC4 | syndecan 4 | 0.048564 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0483723 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0479994 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0477847 |
| EREG | epiregulin | 0.0477194 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0466514 |
| LAMC2 | laminin, gamma 2 | 0.0461303 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0459814 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0456656 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0455012 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0450742 |
| RBM25 | RNA binding motif protein 25 | 0.0450379 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0448633 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.043994 |
| EZR | ezrin | 0.043917 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0424641 |
| ENO1 | enolase 1, (alpha) | 0.0402731 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0398753 |
| NUP58 | nucleoporin 58 | 0.0398465 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.039709 |
| OXR1 | oxidation resistance 1 | 0.0394552 |
| PCBP2 | poly(rC) binding protein 2 | 0.0387402 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0380823 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0376374 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0374108 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0360875 |
| SLMAP | sarcolemma associated protein | 0.0357751 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.035514 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0352959 |
| TPM3 | tropomyosin 3 | 0.0352857 |
| NDRG1 | N-myc downstream regulated 1 | 0.0349192 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.034577 |
| VMP1 | vacuole membrane protein 1 | 0.0345048 |
| USP3 | ubiquitin specific peptidase 3 | 0.0344919 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0344844 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0339081 |
| COPA | coatomer protein complex, subunit alpha | 0.0337402 |
| RNF145 | ring finger protein 145 | 0.0334121 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0333166 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0332552 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0330671 |
| TXNIP | thioredoxin interacting protein | 0.0328369 |
| MED13L | mediator complex subunit 13-like | 0.0326871 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0325885 |
| NEK7 | NIMA-related kinase 7 | 0.0320654 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0318572 |
| ZNF292 | zinc finger protein 292 | 0.0318041 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0317667 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0314819 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0313449 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0309917 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0309022 |
| WDR45B | WD repeat domain 45B | 0.0306766 |
| CDC73 | cell division cycle 73 | 0.0305242 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0301841 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0300481 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0297594 |
| CALU | calumenin | 0.0297386 |
| PKM | pyruvate kinase, muscle | 0.0296647 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.02961 |
| CCNL1 | cyclin L1 | 0.0295697 |
| RPLP0 | ribosomal protein, large, P0 | 0.0294685 |
| RLF | rearranged L-myc fusion | 0.0294318 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0293574 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0292964 |
| ARRDC3 | arrestin domain containing 3 | 0.0291053 |
| CPOX | coproporphyrinogen oxidase | 0.0289748 |
| CENPF | centromere protein F, 350/400kDa | 0.0288714 |
| DIAPH1 | diaphanous-related formin 1 | 0.0282377 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0282084 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0279324 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0275276 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0274898 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0929389 |
| FHIT | fragile histidine triad | -0.0836801 |
| HMGA2 | high mobility group AT-hook 2 | -0.0826974 |
| RAD51B | RAD51 paralog B | -0.078403 |
| VCL | vinculin | -0.0713904 |
| IER3 | immediate early response 3 | -0.0624892 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0520663 |
| LAMA4 | laminin, alpha 4 | -0.0508976 |
| EXOC4 | exocyst complex component 4 | -0.0484259 |
| GPC5 | glypican 5 | -0.0465875 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0453687 |
| EGR1 | early growth response 1 | -0.0453325 |
| FLOT1 | flotillin 1 | -0.0436496 |
| RCOR1 | REST corepressor 1 | -0.0427829 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0417604 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0369897 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0338988 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | -0.0338563 |
| RPS24 | ribosomal protein S24 | -0.0335076 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.031752 |
| CMIP | c-Maf inducing protein | -0.0311509 |
| RPL35A | ribosomal protein L35a | -0.031033 |
| CUX1 | cut-like homeobox 1 | -0.0296301 |
| RPL34 | ribosomal protein L34 | -0.0288827 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0251544 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0244396 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0241204 |
| RPL31 | ribosomal protein L31 | -0.0240072 |
| CDK13 | cyclin-dependent kinase 13 | -0.0235645 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0234942 |
| SEPTIN9 | septin 9 | -0.0233417 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0225084 |
| HDAC4 | histone deacetylase 4 | -0.0223422 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.02215 |
| EFNB2 | ephrin-B2 | -0.0218753 |
| CCND1 | cyclin D1 | -0.0215816 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0215309 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0210271 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0208625 |
| WWOX | WW domain containing oxidoreductase | -0.0207247 |
| INTS6 | integrator complex subunit 6 | -0.0204731 |
| FHL2 | four and a half LIM domains 2 | -0.0201965 |
| ABR | active BCR-related | -0.0199228 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0186305 |
| PHF14 | PHD finger protein 14 | -0.0182046 |
| AEBP2 | AE binding protein 2 | -0.0178416 |
| RASAL2 | RAS protein activator like 2 | -0.017189 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0171639 |
| ZBTB7C | zinc finger and BTB domain containing 7C | -0.0170291 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0169485 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0169135 |
| RPL9 | ribosomal protein L9 | -0.0168105 |
| RPL26 | ribosomal protein L26 | -0.0166001 |
| HM13 | histocompatibility (minor) 13 | -0.0165123 |
| MTAP | methylthioadenosine phosphorylase | -0.0162862 |
| GLCCI1 | glucocorticoid induced 1 | -0.0162063 |
| AOPEP | aminopeptidase O (putative) | -0.0160146 |
| GATAD2A | GATA zinc finger domain containing 2A | -0.0159492 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0152806 |
| RPS17 | ribosomal protein S17 | -0.0152464 |
| SMAD3 | SMAD family member 3 | -0.0151685 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0151009 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.014961 |
| RRM2 | ribonucleotide reductase M2 | -0.0146957 |
| RPLP1 | ribosomal protein, large, P1 | -0.0146867 |
| CDHR3 | cadherin-related family member 3 | -0.0146078 |
| CHRM3 | cholinergic receptor, muscarinic 3 | -0.0145772 |
| TENM3 | teneurin transmembrane protein 3 | -0.0145711 |
| RPS25 | ribosomal protein S25 | -0.0145366 |
| PCNX4 | pecanex 4 | -0.0145087 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0144346 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0142862 |
| NHSL1 | NHS-like 1 | -0.0138264 |
| COMMD10 | COMM domain containing 10 | -0.0136675 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0134606 |
| RSU1 | Ras suppressor protein 1 | -0.0134249 |
| GPHN | gephyrin | -0.0133714 |
| CCDC138 | coiled-coil domain containing 138 | -0.0133693 |
| ERI2 | ERI1 exoribonuclease family member 2 | -0.0132863 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.013177 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0131352 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0130592 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0130278 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0130185 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0129871 |
| PYGL | phosphorylase, glycogen, liver | -0.012967 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0129446 |
| TNS3 | tensin 3 | -0.0129436 |
| LSMEM2 | leucine-rich single-pass membrane protein 2 | -0.0129431 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.0129333 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | -0.0127941 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0127158 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0126321 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0123042 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0122568 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | -0.0122561 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0121962 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0121862 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.012142 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0121303 |
