| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fedratinib (hydrochloride hydrate) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fedratinib (hydrochloride hydrate)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.265065 |
| INHBA | inhibin, beta A | 0.136181 |
| FN1 | fibronectin 1 | 0.117222 |
| MMP1 | matrix metallopeptidase 1 | 0.114711 |
| COL6A3 | collagen, type VI, alpha 3 | 0.113636 |
| FAM13A | family with sequence similarity 13, member A | 0.110529 |
| VIM | vimentin | 0.103619 |
| SPAG9 | sperm associated antigen 9 | 0.0698547 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0683817 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0680485 |
| ATP13A3 | ATPase type 13A3 | 0.0679175 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0665749 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0647235 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0584536 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0569061 |
| NDRG1 | N-myc downstream regulated 1 | 0.0550239 |
| CALU | calumenin | 0.0539308 |
| GOLGA4 | golgin A4 | 0.0523771 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0523205 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0515896 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0468479 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0455269 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0444181 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0443687 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0435765 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0427438 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0408165 |
| NGLY1 | N-glycanase 1 | 0.040662 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0401372 |
| OGA | O-GlcNAcase | 0.0398977 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0393666 |
| PCBP2 | poly(rC) binding protein 2 | 0.039017 |
| ACTG1 | actin gamma 1 | 0.0377048 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0369375 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0365847 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0362501 |
| B2M | beta-2-microglobulin | 0.0358755 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0345456 |
| SETD5 | SET domain containing 5 | 0.0330414 |
| DST | dystonin | 0.0329687 |
| ZNF292 | zinc finger protein 292 | 0.0327938 |
| SEC24D | SEC24 family member D | 0.0326934 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0321273 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0318917 |
| LDHA | lactate dehydrogenase A | 0.0309782 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0303251 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0288293 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0286895 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0284875 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0283973 |
| NKTR | natural killer cell triggering receptor | 0.0282182 |
| FNIP1 | folliculin interacting protein 1 | 0.027891 |
| MMP12 | matrix metallopeptidase 12 | 0.0277184 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0276309 |
| ENO1 | enolase 1, (alpha) | 0.0274842 |
| GPHN | gephyrin | 0.027248 |
| FMNL2 | formin-like 2 | 0.0265266 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0263167 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0261995 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0257753 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.025528 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0253591 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0253312 |
| MYO10 | myosin X | 0.0252753 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0252283 |
| INSIG1 | insulin induced gene 1 | 0.0251962 |
| HELZ | helicase with zinc finger | 0.0251856 |
| NBAS | neuroblastoma amplified sequence | 0.0251279 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.024909 |
| PDE8A | phosphodiesterase 8A | 0.0248349 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0247579 |
| CENPF | centromere protein F, 350/400kDa | 0.0243364 |
| ADM | adrenomedullin | 0.0242566 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.024226 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0241479 |
| EMP1 | epithelial membrane protein 1 | 0.0240649 |
| SERINC3 | serine incorporator 3 | 0.0240283 |
| LOX | lysyl oxidase | 0.0240104 |
| ARRDC3 | arrestin domain containing 3 | 0.0239072 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | 0.0235926 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0232027 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0228305 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0226881 |
| ANXA5 | annexin A5 | 0.0226284 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0223921 |
| TPM3 | tropomyosin 3 | 0.0220902 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0220675 |
| RUNX1 | runt-related transcription factor 1 | 0.022041 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0219584 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.021818 |
| APAF1 | apoptotic peptidase activating factor 1 | 0.0217967 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.021743 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0215374 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0215005 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0214439 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0212607 |
| APP | amyloid beta (A4) precursor protein | 0.0211851 |
| CDK19 | cyclin-dependent kinase 19 | 0.0208306 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0206945 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0206158 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.137545 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0805707 |
| TMSB10 | thymosin beta 10 | -0.0767556 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0746483 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0610638 |
| HLA-B | major histocompatibility complex, class I, B | -0.0551435 |
| RPL35A | ribosomal protein L35a | -0.0499675 |
| RPLP1 | ribosomal protein, large, P1 | -0.0486806 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0464844 |
| RPL34 | ribosomal protein L34 | -0.0439221 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0414731 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0405678 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0388864 |
| RPS8 | ribosomal protein S8 | -0.0386202 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0374326 |
| RPS6 | ribosomal protein S6 | -0.037128 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0344662 |
| CAVIN1 | caveolae associated protein 1 | -0.0342712 |
| FTL | ferritin, light polypeptide | -0.0327532 |
| RPS12 | ribosomal protein S12 | -0.0326012 |
| RPL37A | ribosomal protein L37a | -0.0313914 |
| RPLP2 | ribosomal protein, large, P2 | -0.0312605 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0301291 |
| CALD1 | caldesmon 1 | -0.029582 |
| RPS19 | ribosomal protein S19 | -0.0284669 |
| EGFR | epidermal growth factor receptor | -0.0280724 |
| IER3 | immediate early response 3 | -0.0279357 |
| RPL31 | ribosomal protein L31 | -0.0267073 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0266834 |
| VCL | vinculin | -0.0266647 |
| RPL26 | ribosomal protein L26 | -0.0263788 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0262546 |
| RPL28 | ribosomal protein L28 | -0.0261337 |
| IGF2 | insulin-like growth factor 2 | -0.0260427 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.025357 |
| RPS25 | ribosomal protein S25 | -0.0253213 |
| RPS16 | ribosomal protein S16 | -0.0248294 |
| RPL13A | ribosomal protein L13a | -0.0243251 |
| HMGA2 | high mobility group AT-hook 2 | -0.0241782 |
| PTMA | prothymosin, alpha | -0.0237042 |
| RPL23 | ribosomal protein L23 | -0.022927 |
| RPS24 | ribosomal protein S24 | -0.0227006 |
| RPS20 | ribosomal protein S20 | -0.0224663 |
| COL1A2 | collagen, type I, alpha 2 | -0.0220939 |
| RPL38 | ribosomal protein L38 | -0.0217582 |
| RPS27A | ribosomal protein S27a | -0.0214297 |
| COL3A1 | collagen, type III, alpha 1 | -0.0213145 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0211768 |
| RPL35 | ribosomal protein L35 | -0.0209258 |
| RPL9 | ribosomal protein L9 | -0.0207459 |
| RPL27 | ribosomal protein L27 | -0.0201575 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0200315 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0199435 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0199043 |
| RPS21 | ribosomal protein S21 | -0.0198974 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0192675 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0191629 |
| RPS29 | ribosomal protein S29 | -0.0190849 |
| RPL12 | ribosomal protein L12 | -0.0190655 |
| TPM4 | tropomyosin 4 | -0.0188431 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0188166 |
| S100A10 | S100 calcium binding protein A10 | -0.0184854 |
| RPL7A | ribosomal protein L7a | -0.0184668 |
| FRMD4A | FERM domain containing 4A | -0.0183756 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0183186 |
| COL5A3 | collagen, type V, alpha 3 | -0.0180252 |
| RPL19 | ribosomal protein L19 | -0.0179835 |
| GLIS3 | GLIS family zinc finger 3 | -0.0176498 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0175962 |
| PARD3 | par-3 family cell polarity regulator | -0.017352 |
| RPL5 | ribosomal protein L5 | -0.0173264 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0170484 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0168514 |
| CLMP | CXADR-like membrane protein | -0.0167807 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0166909 |
| CDH13 | cadherin 13 | -0.0165573 |
| RPS23 | ribosomal protein S23 | -0.0164918 |
| RACK1 | receptor for activated C kinase 1 | -0.0164097 |
| KIAA1549L | KIAA1549-like | -0.0163776 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.016337 |
| RPL36 | ribosomal protein L36 | -0.0161214 |
| COL5A1 | collagen, type V, alpha 1 | -0.016009 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0159785 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.015891 |
| RPS14 | ribosomal protein S14 | -0.0157971 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0157035 |
| TPM1 | tropomyosin 1 (alpha) | -0.0156539 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0155257 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0153962 |
| CALR | calreticulin | -0.0151279 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0150823 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0149608 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0149004 |
| CCND1 | cyclin D1 | -0.0148966 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0148077 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0147344 |
| LRRC23 | leucine rich repeat containing 23 | -0.0146818 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0146287 |
| RPL11 | ribosomal protein L11 | -0.0144161 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0144089 |
