Fenofibrate Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A chlorobenzophenone that is (4-chlorophenyl)(phenyl)methanone substituted by a [2-methyl-1-oxo-1-(propan-2-yloxy)propan-2-yl]oxy group at position 1 on the phenyl ring. (Chemical Entities of Biological Interest Ontology, CHEBI_5001)
External Link http://ctdbase.org/detail.go?type=chem&acc=D011345
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Genes

83 genes/proteins interacting with the chemical Fenofibrate from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
A1BG alpha-1-B glycoprotein
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ACAA2 acetyl-CoA acyltransferase 2
ACSL1 acyl-CoA synthetase long-chain family member 1
ADIPOQ adiponectin, C1Q and collagen domain containing
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALB albumin
ANXA3 annexin A3
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOC3 apolipoprotein C-III
APP amyloid beta (A4) precursor protein
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BCKDK branched chain ketoacid dehydrogenase kinase
BDH1 3-hydroxybutyrate dehydrogenase, type 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CD40LG CD40 ligand
CPT2 carnitine palmitoyltransferase 2
CRAT carnitine O-acetyltransferase
CRP C-reactive protein, pentraxin-related
CX3CL1 chemokine (C-X3-C motif) ligand 1
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
ECH1 enoyl CoA hydratase 1, peroxisomal
EDN1 endothelin 1
ETFDH electron-transferring-flavoprotein dehydrogenase
F2 coagulation factor II (thrombin)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FGF21 fibroblast growth factor 21
GATA4 GATA binding protein 4
GSTP1 glutathione S-transferase pi 1
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
IFNG interferon, gamma
IL12B interleukin 12B
IL1B interleukin 1, beta
IL6 interleukin 6
JUN jun proto-oncogene
KRT18 keratin 18, type I
KRT8 keratin 8, type II
LPL lipoprotein lipase
MITF microphthalmia-associated transcription factor
MKI67 marker of proliferation Ki-67
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS3 nitric oxide synthase 3 (endothelial cell)
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
PCNA proliferating cell nuclear antigen
PCSK9 proprotein convertase subtilisin/kexin type 9
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PON1 paraoxonase 1
PPARA peroxisome proliferator-activated receptor alpha
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PSEN1 presenilin 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SCARB1 scavenger receptor class B, member 1
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
STK11 serine/threonine kinase 11
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TYR tyrosinase