| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fenofibrate perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fenofibrate_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.267739 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.189111 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.177647 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.15328 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.146846 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.146588 |
| FBN1 | fibrillin 1 | 0.146134 |
| AHNAK | AHNAK nucleoprotein | 0.10834 |
| UBC | ubiquitin C | 0.0960599 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0882326 |
| COL3A1 | collagen, type III, alpha 1 | 0.0819002 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0794434 |
| COL5A2 | collagen, type V, alpha 2 | 0.0788877 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0766411 |
| CALR | calreticulin | 0.0759701 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0751696 |
| CANX | calnexin | 0.0742082 |
| OGA | O-GlcNAcase | 0.0741889 |
| NAV1 | neuron navigator 1 | 0.0725734 |
| DST | dystonin | 0.0725475 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0718037 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.071664 |
| LDHA | lactate dehydrogenase A | 0.0713573 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0701056 |
| NAV2 | neuron navigator 2 | 0.0677041 |
| AUTS2 | autism susceptibility candidate 2 | 0.065777 |
| LOXL2 | lysyl oxidase-like 2 | 0.0657222 |
| SBF2 | SET binding factor 2 | 0.0654083 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0647337 |
| LOX | lysyl oxidase | 0.063427 |
| FLNB | filamin B, beta | 0.0623401 |
| PODXL | podocalyxin-like | 0.0602918 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.05994 |
| APP | amyloid beta (A4) precursor protein | 0.0597657 |
| MYOF | myoferlin | 0.0594746 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0590695 |
| SEPTIN9 | septin 9 | 0.0589311 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0576105 |
| THBS2 | thrombospondin 2 | 0.0557939 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0545605 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0541791 |
| CD44 | CD44 molecule (Indian blood group) | 0.0517391 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0510194 |
| PGK1 | phosphoglycerate kinase 1 | 0.0497606 |
| ATP13A3 | ATPase type 13A3 | 0.0495045 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0479066 |
| COL1A2 | collagen, type I, alpha 2 | 0.046767 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0464812 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0460563 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0442253 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0438422 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0436801 |
| FNIP1 | folliculin interacting protein 1 | 0.043367 |
| GPC6 | glypican 6 | 0.0423289 |
| MAP4 | microtubule-associated protein 4 | 0.0419058 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0418613 |
| PLAT | plasminogen activator, tissue | 0.0415755 |
| ZNF292 | zinc finger protein 292 | 0.0414535 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0413438 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0406152 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0404889 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0396341 |
| RAI14 | retinoic acid induced 14 | 0.0393431 |
| SQSTM1 | sequestosome 1 | 0.0390731 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.038972 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0389693 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0389131 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0386305 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0384554 |
| RUNX1 | runt-related transcription factor 1 | 0.0384445 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0378158 |
| TMSB4X | thymosin beta 4, X-linked | 0.0374004 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0365396 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0363685 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0359401 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.03591 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0356137 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0352958 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0352628 |
| COL5A1 | collagen, type V, alpha 1 | 0.0340222 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0339345 |
| YEATS2 | YEATS domain containing 2 | 0.0339271 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0335857 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0335477 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0334908 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0329714 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0328753 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0326273 |
| PRELID2 | PRELI domain containing 2 | 0.0323591 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0322879 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0322519 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0320063 |
| SPAG9 | sperm associated antigen 9 | 0.0318377 |
| DENND5A | DENN/MADD domain containing 5A | 0.03179 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0316357 |
| SETD5 | SET domain containing 5 | 0.0312223 |
| ABI1 | abl-interactor 1 | 0.0308648 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0305698 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0303134 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0302724 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0928464 |
| TMSB10 | thymosin beta 10 | -0.0911185 |
| MT2A | metallothionein 2A | -0.0755827 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0619262 |
| NDRG1 | N-myc downstream regulated 1 | -0.0438411 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0400964 |
| VIM | vimentin | -0.0377113 |
| FTL | ferritin, light polypeptide | -0.0318438 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0286651 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0270112 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0261721 |
| RPL35A | ribosomal protein L35a | -0.0240269 |
| RPLP1 | ribosomal protein, large, P1 | -0.0213954 |
| PFN1 | profilin 1 | -0.0208444 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0202592 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0199005 |
| RPL28 | ribosomal protein L28 | -0.0198511 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0197022 |
| RPL36 | ribosomal protein L36 | -0.0194834 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0194563 |
| CD81 | CD81 molecule | -0.0193816 |
| HLA-B | major histocompatibility complex, class I, B | -0.0189643 |
| HLA-C | major histocompatibility complex, class I, C | -0.0179874 |
| RPLP2 | ribosomal protein, large, P2 | -0.0178174 |
| FN1 | fibronectin 1 | -0.0175348 |
| RPS6 | ribosomal protein S6 | -0.0164835 |
| MT1X | metallothionein 1X | -0.0160673 |
| BSG | basigin (Ok blood group) | -0.0159294 |
| S100A11 | S100 calcium binding protein A11 | -0.0157444 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0156555 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0155646 |
| MYADM | myeloid-associated differentiation marker | -0.0155323 |
| MTDH | metadherin | -0.0151316 |
| TBCA | tubulin folding cofactor A | -0.0150996 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0148308 |
| SEC61G | Sec61 gamma subunit | -0.0148056 |
| RPL9 | ribosomal protein L9 | -0.0146899 |
| RPS19 | ribosomal protein S19 | -0.0146774 |
| RPS14 | ribosomal protein S14 | -0.0143684 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0143237 |
| LMNA | lamin A/C | -0.0142773 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0142284 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0141237 |
| ATF4 | activating transcription factor 4 | -0.013873 |
| RPL37A | ribosomal protein L37a | -0.0138482 |
| NABP1 | nucleic acid binding protein 1 | -0.0136348 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.013578 |
| MRC2 | mannose receptor, C type 2 | -0.013135 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0131138 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.012785 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0127054 |
| FOSL1 | FOS-like antigen 1 | -0.0124853 |
| CTSD | cathepsin D | -0.0123627 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0122182 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0120472 |
| HLA-A | major histocompatibility complex, class I, A | -0.012038 |
| RPL32 | ribosomal protein L32 | -0.0119022 |
| PLXNA2 | plexin A2 | -0.0118685 |
| EGR1 | early growth response 1 | -0.0117133 |
| RPS15 | ribosomal protein S15 | -0.011525 |
| RPS12 | ribosomal protein S12 | -0.0113635 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0113111 |
| POTEF | POTE ankyrin domain family, member F | -0.0112343 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.011145 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0109323 |
| RPL35 | ribosomal protein L35 | -0.0108196 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0105381 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.010535 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0104922 |
| RPL11 | ribosomal protein L11 | -0.0104042 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.010285 |
| GNAS | GNAS complex locus | -0.010132 |
| RAD23A | RAD23 homolog A (S. cerevisiae) | -0.00995874 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00995302 |
| UBL5 | ubiquitin-like 5 | -0.00992773 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00991413 |
| FLT1 | fms-related tyrosine kinase 1 | -0.00990946 |
| TMEM165 | transmembrane protein 165 | -0.00990685 |
| RPS20 | ribosomal protein S20 | -0.00975283 |
| RPS8 | ribosomal protein S8 | -0.00974121 |
| RPS21 | ribosomal protein S21 | -0.00965171 |
| TTYH3 | tweety family member 3 | -0.009642 |
| S100A4 | S100 calcium binding protein A4 | -0.00960134 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.00955965 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00940249 |
| TXNIP | thioredoxin interacting protein | -0.00938432 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00936672 |
| CST3 | cystatin C | -0.00933067 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.00923218 |
| DSTN | destrin (actin depolymerizing factor) | -0.00920419 |
| RPS23 | ribosomal protein S23 | -0.00909388 |
| INTS6 | integrator complex subunit 6 | -0.00909132 |
| GUK1 | guanylate kinase 1 | -0.00895178 |
| RPS27 | ribosomal protein S27 | -0.00893642 |
| RPS3 | ribosomal protein S3 | -0.00884662 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00884609 |
| IL7R | interleukin 7 receptor | -0.00883114 |
| FMN2 | formin 2 | -0.00873688 |
| TOR4A | torsin family 4, member A | -0.00873077 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.00870498 |