| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fenofibrate perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fenofibrate_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.270731 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.129755 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.103314 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.101276 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0982377 |
| YAP1 | Yes-associated protein 1 | 0.0801943 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.076177 |
| VMP1 | vacuole membrane protein 1 | 0.0758056 |
| ANXA1 | annexin A1 | 0.0739403 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0652044 |
| CCNL1 | cyclin L1 | 0.0640333 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0615655 |
| UBC | ubiquitin C | 0.0613371 |
| PCBP2 | poly(rC) binding protein 2 | 0.0590658 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.054842 |
| TPM3 | tropomyosin 3 | 0.0544882 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0542263 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0539944 |
| RRM2 | ribonucleotide reductase M2 | 0.0533139 |
| RPL3 | ribosomal protein L3 | 0.052851 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.052684 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0522149 |
| YBX1 | Y box binding protein 1 | 0.0495274 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.049261 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0488582 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0483307 |
| MED13L | mediator complex subunit 13-like | 0.0483228 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0474859 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0470879 |
| TXNRD1 | thioredoxin reductase 1 | 0.0470483 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0468828 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0463988 |
| ASPH | aspartate beta-hydroxylase | 0.0451579 |
| NEK7 | NIMA-related kinase 7 | 0.0451486 |
| SET | SET nuclear proto-oncogene | 0.0448044 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0430809 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0429764 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.042804 |
| TNPO1 | transportin 1 | 0.0421999 |
| RBM39 | RNA binding motif protein 39 | 0.042133 |
| LDHA | lactate dehydrogenase A | 0.0419473 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0416013 |
| ECT2 | epithelial cell transforming 2 | 0.0415983 |
| ZNF292 | zinc finger protein 292 | 0.041249 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0404083 |
| ENO1 | enolase 1, (alpha) | 0.0403584 |
| YEATS2 | YEATS domain containing 2 | 0.0397744 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0395988 |
| EPHA6 | EPH receptor A6 | 0.0395876 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.038938 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0386012 |
| XPO1 | exportin 1 | 0.0382188 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0380085 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.037523 |
| POTEF | POTE ankyrin domain family, member F | 0.0371906 |
| CPOX | coproporphyrinogen oxidase | 0.0371246 |
| PDGFC | platelet derived growth factor C | 0.036972 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0368465 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0364439 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0364036 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0360163 |
| TBK1 | TANK-binding kinase 1 | 0.0358162 |
| MATR3 | matrin 3 | 0.0352284 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0350649 |
| NBAS | neuroblastoma amplified sequence | 0.0349341 |
| THOC1 | THO complex 1 | 0.034317 |
| PNN | pinin, desmosome associated protein | 0.0341307 |
| NCKAP1 | NCK-associated protein 1 | 0.0340477 |
| RPS2 | ribosomal protein S2 | 0.0340128 |
| RPL4 | ribosomal protein L4 | 0.0339285 |
| ARRDC3 | arrestin domain containing 3 | 0.0338083 |
| USP34 | ubiquitin specific peptidase 34 | 0.0337545 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.033733 |
| TMEM41B | transmembrane protein 41B | 0.0335995 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0334137 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0332037 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0328341 |
| JMJD1C | jumonji domain containing 1C | 0.0325819 |
| PTMS | parathymosin | 0.0324199 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0323104 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0321569 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0321553 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.032061 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.032004 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0319769 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0316556 |
| ATP11A | ATPase, class VI, type 11A | 0.0314989 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0314875 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.031476 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0310537 |
| PREPL | prolyl endopeptidase-like | 0.0308094 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0305541 |
| RTN4 | reticulon 4 | 0.0304975 |
| HDGF | hepatoma-derived growth factor | 0.0303947 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0301213 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0298423 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0298358 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.0296616 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0295134 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0294767 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.177963 |
| VIM | vimentin | -0.138924 |
| PCDH7 | protocadherin 7 | -0.0995565 |
| TMSB10 | thymosin beta 10 | -0.0991147 |
| NLGN1 | neuroligin 1 | -0.0834004 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0693347 |
| HMGA2 | high mobility group AT-hook 2 | -0.0675459 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0655365 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0632518 |
| RASAL2 | RAS protein activator like 2 | -0.0576847 |
| ZNF804A | zinc finger protein 804A | -0.0504623 |
| RPL35A | ribosomal protein L35a | -0.0479594 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0398619 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0389109 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0384758 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0360656 |
| GCG | glucagon | -0.0351591 |
| EGR1 | early growth response 1 | -0.0341859 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0309519 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0304631 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0300269 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0298856 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0297108 |
| CMIP | c-Maf inducing protein | -0.0295599 |
| CCND1 | cyclin D1 | -0.0295098 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0287043 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0284872 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0274924 |
| CAVIN1 | caveolae associated protein 1 | -0.0271762 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0252289 |
| ADIPOR2 | adiponectin receptor 2 | -0.0251285 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0247524 |
| EHBP1 | EH domain binding protein 1 | -0.0244256 |
| NABP1 | nucleic acid binding protein 1 | -0.0242838 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0241792 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0238875 |
| MYPN | myopalladin | -0.0236651 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0233389 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0230516 |
| RPS21 | ribosomal protein S21 | -0.0228394 |
| RPL36 | ribosomal protein L36 | -0.022382 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0219699 |
| FTL | ferritin, light polypeptide | -0.0216101 |
| BRI3BP | BRI3 binding protein | -0.0215859 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0213613 |
| CUX1 | cut-like homeobox 1 | -0.0211317 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0211269 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0210281 |
| MAP1B | microtubule-associated protein 1B | -0.0197488 |
| EGFR | epidermal growth factor receptor | -0.0196738 |
| AHNAK | AHNAK nucleoprotein | -0.0196512 |
| TEAD4 | TEA domain family member 4 | -0.0196278 |
| ASTN2 | astrotactin 2 | -0.0194568 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0191379 |
| CDK6 | cyclin-dependent kinase 6 | -0.0187981 |
| INTS6 | integrator complex subunit 6 | -0.0187543 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0187233 |
| MTAP | methylthioadenosine phosphorylase | -0.0186784 |
| HMGB1 | high mobility group box 1 | -0.0185231 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0184198 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0174455 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0171473 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0171352 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0168943 |
| COMMD10 | COMM domain containing 10 | -0.0167563 |
| TBCA | tubulin folding cofactor A | -0.0166426 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0160741 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0159639 |
| BPTF | bromodomain PHD finger transcription factor | -0.0157894 |
| CALD1 | caldesmon 1 | -0.0154035 |
| FSTL5 | follistatin-like 5 | -0.0150835 |
| CEP112 | centrosomal protein 112kDa | -0.0149033 |
| GNAS | GNAS complex locus | -0.0148398 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.0146172 |
| UBB | ubiquitin B | -0.0145485 |
| RPS10 | ribosomal protein S10 | -0.0145009 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0143369 |
| ZMYM4 | zinc finger, MYM-type 4 | -0.0143148 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0142714 |
| NSD1 | nuclear receptor binding SET domain protein 1 | -0.0141187 |
| RNF216 | ring finger protein 216 | -0.0139546 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0139266 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0139175 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | -0.0139169 |
| COX6A1 | cytochrome c oxidase subunit VIa polypeptide 1 | -0.0138363 |
| RPS16 | ribosomal protein S16 | -0.0136252 |
| EDARADD | EDAR-associated death domain | -0.0135692 |
| ACTG1 | actin gamma 1 | -0.0135066 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0132521 |
| RPLP1 | ribosomal protein, large, P1 | -0.0131619 |
| AK1 | adenylate kinase 1 | -0.0130953 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0130719 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0129425 |
| LRRC23 | leucine rich repeat containing 23 | -0.0128591 |
| RPL38 | ribosomal protein L38 | -0.0128424 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0128246 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0126213 |
| PRDX1 | peroxiredoxin 1 | -0.012575 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0125441 |
| NAV3 | neuron navigator 3 | -0.012507 |
