| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fenofibrate perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fenofibrate_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.302661 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.110349 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0982856 |
| FN1 | fibronectin 1 | 0.0921777 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0764083 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.069437 |
| CANX | calnexin | 0.0689047 |
| ATP13A3 | ATPase type 13A3 | 0.0652918 |
| CADM1 | cell adhesion molecule 1 | 0.0640306 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0639478 |
| SPAG9 | sperm associated antigen 9 | 0.0629462 |
| MT2A | metallothionein 2A | 0.0539461 |
| CALR | calreticulin | 0.0512915 |
| PTMA | prothymosin, alpha | 0.0504817 |
| SMAD3 | SMAD family member 3 | 0.0486522 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.047286 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0466111 |
| ZNF292 | zinc finger protein 292 | 0.0465508 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0446107 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0433463 |
| ARRDC3 | arrestin domain containing 3 | 0.0417546 |
| UBC | ubiquitin C | 0.0409832 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0405914 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0402352 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0395356 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0383431 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0377837 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0365373 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0365 |
| RLF | rearranged L-myc fusion | 0.0358338 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0358023 |
| FNDC3B | fibronectin type III domain containing 3B | 0.03566 |
| PTK2 | protein tyrosine kinase 2 | 0.035397 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0349953 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0330509 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0327142 |
| OGA | O-GlcNAcase | 0.0326341 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0320058 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0318422 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0317493 |
| APP | amyloid beta (A4) precursor protein | 0.031062 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0309885 |
| USP3 | ubiquitin specific peptidase 3 | 0.030754 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.030455 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0304426 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0301647 |
| LDHA | lactate dehydrogenase A | 0.0299476 |
| GOLGA4 | golgin A4 | 0.0299401 |
| POSTN | periostin, osteoblast specific factor | 0.0298343 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0296575 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0290185 |
| RBM39 | RNA binding motif protein 39 | 0.0288819 |
| MRTFA | myocardin related transcription factor A | 0.0281691 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0280226 |
| RASA2 | RAS p21 protein activator 2 | 0.0279619 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0277378 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0275292 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0271826 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0265969 |
| VEGFA | vascular endothelial growth factor A | 0.0260736 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0260618 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0260268 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0254172 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.025406 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0253256 |
| RPS8 | ribosomal protein S8 | 0.0247974 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0247226 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0241605 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0240634 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0237766 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0237304 |
| NAV2 | neuron navigator 2 | 0.023579 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0235379 |
| HMGB2 | high mobility group box 2 | 0.0234409 |
| DENND5A | DENN/MADD domain containing 5A | 0.0234184 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.023396 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0232772 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0231365 |
| QKI | QKI, KH domain containing, RNA binding | 0.0228412 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0226981 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0224668 |
| RPS3 | ribosomal protein S3 | 0.0224609 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0223783 |
| CALU | calumenin | 0.0223343 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0222811 |
| FMNL2 | formin-like 2 | 0.022276 |
| RPL3 | ribosomal protein L3 | 0.0221455 |
| PDE8A | phosphodiesterase 8A | 0.0221336 |
| IER3 | immediate early response 3 | 0.0220791 |
| YBX1 | Y box binding protein 1 | 0.021683 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0216345 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0214679 |
| RNF145 | ring finger protein 145 | 0.0214064 |
| TMSB4X | thymosin beta 4, X-linked | 0.0213596 |
| RYBP | RING1 and YY1 binding protein | 0.0212987 |
| SEPTIN7 | septin 7 | 0.0212887 |
| RPL26 | ribosomal protein L26 | 0.0212303 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0210845 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0208281 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0207086 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.305143 |
| VIM | vimentin | -0.117995 |
| NDRG1 | N-myc downstream regulated 1 | -0.114255 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0986503 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0920048 |
| COL1A1 | collagen, type I, alpha 1 | -0.0903637 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0896607 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0801375 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0708807 |
| COL1A2 | collagen, type I, alpha 2 | -0.0701596 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0685181 |
| CALD1 | caldesmon 1 | -0.0617268 |
| CDH13 | cadherin 13 | -0.0590784 |
| FBN1 | fibrillin 1 | -0.0577232 |
| GLIS3 | GLIS family zinc finger 3 | -0.0567079 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0562673 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0543185 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0522651 |
| TMSB10 | thymosin beta 10 | -0.0517063 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0456238 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0440021 |
| VCAN | versican | -0.0433183 |
| CLMP | CXADR-like membrane protein | -0.0424219 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0412119 |
| NAV1 | neuron navigator 1 | -0.0382176 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0370194 |
| ASPH | aspartate beta-hydroxylase | -0.0362184 |
| CNTN5 | contactin 5 | -0.0344235 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0336309 |
| POTEF | POTE ankyrin domain family, member F | -0.0324261 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0322247 |
| EGR1 | early growth response 1 | -0.0321161 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0316592 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0306195 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0306035 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0299986 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0299287 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0294424 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0289791 |
| MAP1B | microtubule-associated protein 1B | -0.0281654 |
| COL5A1 | collagen, type V, alpha 1 | -0.028093 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0279065 |
| HLA-B | major histocompatibility complex, class I, B | -0.0270742 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0265642 |
| PRSS23 | protease, serine, 23 | -0.0264418 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0258612 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0257983 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0249554 |
| NEK10 | NIMA-related kinase 10 | -0.0249467 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0249383 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0241946 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0238775 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0236654 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.023475 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0234716 |
| VCL | vinculin | -0.0234134 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.023367 |
| TPM4 | tropomyosin 4 | -0.0233364 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0232244 |
| FOXP1 | forkhead box P1 | -0.0229188 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.022547 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0215114 |
| ACTG1 | actin gamma 1 | -0.0214682 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0213592 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0210444 |
| SDC2 | syndecan 2 | -0.0210394 |
| NRP1 | neuropilin 1 | -0.0208467 |
| NREP | neuronal regeneration related protein | -0.0207571 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0205808 |
| CUX1 | cut-like homeobox 1 | -0.0205257 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0200415 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0197041 |
| S100A9 | S100 calcium binding protein A9 | -0.0192308 |
| OXR1 | oxidation resistance 1 | -0.0189881 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0189471 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0189372 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0185791 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0185052 |
| STC1 | stanniocalcin 1 | -0.0182971 |
| LMO4 | LIM domain only 4 | -0.0180415 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0179884 |
| HDAC9 | histone deacetylase 9 | -0.0175236 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.017397 |
| HLA-A | major histocompatibility complex, class I, A | -0.017094 |
| PRRX1 | paired related homeobox 1 | -0.0170845 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0169665 |
| CMIP | c-Maf inducing protein | -0.0168242 |
| OSMR | oncostatin M receptor | -0.0167735 |
| IL6 | interleukin 6 | -0.0164963 |
| CST3 | cystatin C | -0.0159594 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0157917 |
| CTSB | cathepsin B | -0.0157096 |
| EPHB1 | EPH receptor B1 | -0.0156041 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.015598 |
| STC2 | stanniocalcin 2 | -0.015502 |
| FRMD4A | FERM domain containing 4A | -0.0153231 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0151425 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0151106 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0149527 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0147869 |
