| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fenofibrate perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fenofibrate_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC38A2 | solute carrier family 38, member 2 | 0.223619 |
| FN1 | fibronectin 1 | 0.212948 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.200441 |
| FNDC3B | fibronectin type III domain containing 3B | 0.190699 |
| C3 | complement component 3 | 0.170983 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.158632 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.149145 |
| ENO1 | enolase 1, (alpha) | 0.127116 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.120933 |
| GPC3 | glypican 3 | 0.110137 |
| DSPP | dentin sialophosphoprotein | 0.108003 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.104351 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.102246 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0847986 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0820463 |
| ATXN1 | ataxin 1 | 0.0767633 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0762429 |
| VEGFA | vascular endothelial growth factor A | 0.0738011 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0733039 |
| EHBP1 | EH domain binding protein 1 | 0.0714161 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0682652 |
| TF | transferrin | 0.0678876 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0638038 |
| ASPH | aspartate beta-hydroxylase | 0.0624255 |
| DST | dystonin | 0.0613346 |
| TNS1 | tensin 1 | 0.0590677 |
| VCL | vinculin | 0.0562127 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0555593 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0544413 |
| PEG3 | paternally expressed 3 | 0.0532857 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0527871 |
| UBC | ubiquitin C | 0.0525913 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0520891 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0512735 |
| FAT1 | FAT atypical cadherin 1 | 0.0512725 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.051007 |
| FRMD5 | FERM domain containing 5 | 0.0492734 |
| DTNA | dystrobrevin, alpha | 0.049242 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0484981 |
| MSI2 | musashi RNA-binding protein 2 | 0.0474421 |
| GPC6 | glypican 6 | 0.0459198 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0455135 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0452931 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.045064 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0443508 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0423283 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0418394 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0415677 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0415455 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0414689 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0406596 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0398865 |
| RPL3 | ribosomal protein L3 | 0.0394818 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0390712 |
| PLIN2 | perilipin 2 | 0.0386229 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0385775 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.038474 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0382055 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0378989 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0378552 |
| CP | ceruloplasmin (ferroxidase) | 0.0377836 |
| AFDN | afadin, adherens junction formation factor | 0.0373863 |
| PTK2 | protein tyrosine kinase 2 | 0.0369039 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0368133 |
| SBF2 | SET binding factor 2 | 0.0362744 |
| FMNL2 | formin-like 2 | 0.0362493 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0361548 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0361141 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0358997 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.035822 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0350107 |
| KRT8 | keratin 8, type II | 0.0346694 |
| RNF213 | ring finger protein 213 | 0.0345439 |
| OSMR | oncostatin M receptor | 0.0344989 |
| RUNX1 | runt-related transcription factor 1 | 0.0343437 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0343014 |
| FLNB | filamin B, beta | 0.0341282 |
| LDHA | lactate dehydrogenase A | 0.0336661 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0331864 |
| KIAA1217 | KIAA1217 | 0.0329374 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0328455 |
| RAD51B | RAD51 paralog B | 0.0328384 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0322318 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0320913 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0320688 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0317997 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0315757 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0314234 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.031203 |
| AHR | aryl hydrocarbon receptor | 0.0311657 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0311065 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0308372 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0306684 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0304774 |
| MALRD1 | MAM and LDL receptor class A domain containing 1 | 0.0299715 |
| CANX | calnexin | 0.0298429 |
| ATP10A | ATPase, class V, type 10A | 0.0297607 |
| MALT1 | MALT1 paracaspase | 0.029699 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0295662 |
| RTN4 | reticulon 4 | 0.0295588 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.277384 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0969756 |
| RPL11 | ribosomal protein L11 | -0.0933264 |
| RPS6 | ribosomal protein S6 | -0.0856463 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0804745 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0710964 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0523487 |
| RPS8 | ribosomal protein S8 | -0.0517595 |
| RPS12 | ribosomal protein S12 | -0.0492635 |
| MT2A | metallothionein 2A | -0.0478073 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0472667 |
| FTL | ferritin, light polypeptide | -0.0445376 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0442209 |
| APOE | apolipoprotein E | -0.042163 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0411686 |
| RPL5 | ribosomal protein L5 | -0.0410688 |
| RPS19 | ribosomal protein S19 | -0.0402677 |
| RPS2 | ribosomal protein S2 | -0.0397706 |
| RPL37A | ribosomal protein L37a | -0.0396464 |
| RPL7 | ribosomal protein L7 | -0.0384611 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0384398 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0382953 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0379839 |
| RPS21 | ribosomal protein S21 | -0.0371508 |
| RPL9 | ribosomal protein L9 | -0.035552 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0346686 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0345302 |
| FOXP1 | forkhead box P1 | -0.0330043 |
| RPL31 | ribosomal protein L31 | -0.0324337 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0318328 |
| JMJD1C | jumonji domain containing 1C | -0.0314035 |
| RPLP0 | ribosomal protein, large, P0 | -0.0313996 |
| RPL35A | ribosomal protein L35a | -0.0313263 |
| MATR3 | matrin 3 | -0.0291924 |
| AHSG | alpha-2-HS-glycoprotein | -0.0290365 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0287632 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0282579 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0281059 |
| RRBP1 | ribosome binding protein 1 | -0.0278338 |
| RPL10A | ribosomal protein L10a | -0.0273632 |
| RPLP1 | ribosomal protein, large, P1 | -0.0270034 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0266454 |
| LCN2 | lipocalin 2 | -0.0264236 |
| PTMA | prothymosin, alpha | -0.0262212 |
| RPLP2 | ribosomal protein, large, P2 | -0.026108 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.025931 |
| RPL26 | ribosomal protein L26 | -0.0255358 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0254308 |
| RPL12 | ribosomal protein L12 | -0.0251749 |
| RPS5 | ribosomal protein S5 | -0.0249415 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0248723 |
| RPL28 | ribosomal protein L28 | -0.0246809 |
| FOXK2 | forkhead box K2 | -0.0246583 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0245987 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.023793 |
| RPS20 | ribosomal protein S20 | -0.0237852 |
| MED13L | mediator complex subunit 13-like | -0.0237697 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0236487 |
| NKTR | natural killer cell triggering receptor | -0.0236318 |
| RPL7A | ribosomal protein L7a | -0.0232023 |
| RPL34 | ribosomal protein L34 | -0.0230819 |
| SVIL | supervillin | -0.0230446 |
| FAM162A | family with sequence similarity 162, member A | -0.0225589 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0225397 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0218169 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.021774 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0216835 |
| WDR45B | WD repeat domain 45B | -0.0216284 |
| ZFR | zinc finger RNA binding protein | -0.0214677 |
| RPS25 | ribosomal protein S25 | -0.0213615 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0212435 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0211838 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.021101 |
| PCBP2 | poly(rC) binding protein 2 | -0.020989 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0208141 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0207281 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0207004 |
| RACK1 | receptor for activated C kinase 1 | -0.02066 |
| RBM39 | RNA binding motif protein 39 | -0.0204704 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0203633 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0202564 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) | -0.0201644 |
| RPS16 | ribosomal protein S16 | -0.0198368 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0196925 |
| H3-3B | H3.3 histone B | -0.0195379 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0194207 |
| CDC27 | cell division cycle 27 | -0.019245 |
| RPS15 | ribosomal protein S15 | -0.0191445 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0188639 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0188384 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0187612 |
| RPL8 | ribosomal protein L8 | -0.0187273 |
| CLU | clusterin | -0.0186379 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.018529 |
| MTDH | metadherin | -0.0184542 |
| RPS24 | ribosomal protein S24 | -0.0183939 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0180843 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0180311 |
| RPS23 | ribosomal protein S23 | -0.0179767 |
| JAK1 | Janus kinase 1 | -0.0179435 |