| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fenofibrate perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fenofibrate_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.334195 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.193095 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.174244 |
| PTMA | prothymosin, alpha | 0.118562 |
| TMSB4X | thymosin beta 4, X-linked | 0.107934 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.102119 |
| CANX | calnexin | 0.0936836 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0910839 |
| UBC | ubiquitin C | 0.0890243 |
| LDHA | lactate dehydrogenase A | 0.0879379 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0848253 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0846025 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0843939 |
| CALR | calreticulin | 0.083346 |
| RAI1 | retinoic acid induced 1 | 0.0823826 |
| PGK1 | phosphoglycerate kinase 1 | 0.0760882 |
| VIM | vimentin | 0.0759052 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0733061 |
| TMSB10 | thymosin beta 10 | 0.0668592 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0628837 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0626096 |
| ENO1 | enolase 1, (alpha) | 0.0605685 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0593538 |
| APP | amyloid beta (A4) precursor protein | 0.0591932 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0562588 |
| OGA | O-GlcNAcase | 0.0559258 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0550769 |
| EZR | ezrin | 0.0548971 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0544481 |
| POTEF | POTE ankyrin domain family, member F | 0.0537316 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.051807 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0511121 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0506827 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0503486 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.05019 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.04902 |
| AHNAK | AHNAK nucleoprotein | 0.0486078 |
| SET | SET nuclear proto-oncogene | 0.0482265 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0475747 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0469624 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0458314 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0456307 |
| TOP1 | topoisomerase (DNA) I | 0.0456306 |
| FMNL2 | formin-like 2 | 0.0449611 |
| ACTG1 | actin gamma 1 | 0.0443007 |
| ZNF292 | zinc finger protein 292 | 0.044114 |
| RACK1 | receptor for activated C kinase 1 | 0.043576 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0431863 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0421098 |
| RPL3 | ribosomal protein L3 | 0.0415361 |
| ANXA1 | annexin A1 | 0.0406764 |
| WDR45B | WD repeat domain 45B | 0.040266 |
| YBX1 | Y box binding protein 1 | 0.0401237 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0400265 |
| MYOF | myoferlin | 0.0397464 |
| LMAN1 | lectin, mannose-binding, 1 | 0.039236 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0388883 |
| RPL4 | ribosomal protein L4 | 0.0384593 |
| PKM | pyruvate kinase, muscle | 0.0380755 |
| RBM39 | RNA binding motif protein 39 | 0.0380161 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0380049 |
| RTN4 | reticulon 4 | 0.037791 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0376207 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0368656 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0365759 |
| GOLGA4 | golgin A4 | 0.0362054 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0357948 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.03547 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0354408 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0353084 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0352498 |
| FTL | ferritin, light polypeptide | 0.0351252 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0350338 |
| HDLBP | high density lipoprotein binding protein | 0.0346886 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.03424 |
| SPAG9 | sperm associated antigen 9 | 0.0341191 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0338697 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0336364 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0334329 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0332865 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0329292 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0328722 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0326197 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0324006 |
| MORF4L2 | mortality factor 4 like 2 | 0.0314431 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0314268 |
| SBF2 | SET binding factor 2 | 0.0314149 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0313197 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0311456 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0311195 |
| RPS4X | ribosomal protein S4, X-linked | 0.0308878 |
| RPS3 | ribosomal protein S3 | 0.0308372 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0306485 |
| FNIP1 | folliculin interacting protein 1 | 0.030483 |
| XPO1 | exportin 1 | 0.0301647 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0297614 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.029641 |
| YEATS2 | YEATS domain containing 2 | 0.0296338 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0295123 |
| PLK2 | polo-like kinase 2 | 0.0292905 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TP63 | tumor protein p63 | -0.187803 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.12599 |
| HLA-B | major histocompatibility complex, class I, B | -0.0904112 |
| MT2A | metallothionein 2A | -0.073563 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0673664 |
| RIGI | RNA sensor RIG-I | -0.0508265 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0501362 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0492908 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0458189 |
| CD44 | CD44 molecule (Indian blood group) | -0.0433278 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0408806 |
| CADM2 | cell adhesion molecule 2 | -0.0395412 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0373888 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0368989 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0355956 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0354663 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0354296 |
| PLSCR1 | phospholipid scramblase 1 | -0.0349362 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0347432 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0336863 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0330768 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0329842 |
| DPYD | dihydropyrimidine dehydrogenase | -0.032722 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0326649 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0322778 |
| SP100 | SP100 nuclear antigen | -0.0320965 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0316008 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.031018 |
| EGR1 | early growth response 1 | -0.0301868 |
| PMP22 | peripheral myelin protein 22 | -0.0288326 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0281594 |
| RNF213 | ring finger protein 213 | -0.026831 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0261145 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0247904 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0246052 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0245124 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0242251 |
| TRIM56 | tripartite motif containing 56 | -0.0242084 |
| TGM2 | transglutaminase 2 | -0.0242067 |
| PDE10A | phosphodiesterase 10A | -0.0241828 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0237143 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0227402 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0206135 |
| MT1E | metallothionein 1E | -0.0206071 |
| CAPRIN2 | caprin family member 2 | -0.0203526 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0203418 |
| RPL35A | ribosomal protein L35a | -0.0201972 |
| ECE1 | endothelin converting enzyme 1 | -0.0199475 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0199257 |
| HMGA1 | high mobility group AT-hook 1 | -0.019698 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0193963 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.019011 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0189292 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0186543 |
| CMIP | c-Maf inducing protein | -0.0185736 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0177258 |
| RUNX1 | runt-related transcription factor 1 | -0.0177203 |
| RPL36 | ribosomal protein L36 | -0.0174514 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0167049 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0165365 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0164834 |
| DPH6 | diphthamine biosynthesis 6 | -0.0164606 |
| RPL38 | ribosomal protein L38 | -0.0164567 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0163869 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0163276 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0163221 |
| TPRG1 | tumor protein p63 regulated 1 | -0.0162517 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0161323 |
| BPTF | bromodomain PHD finger transcription factor | -0.0158964 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0158119 |
| SVIL | supervillin | -0.0157029 |
| HDAC9 | histone deacetylase 9 | -0.0156848 |
| NEK10 | NIMA-related kinase 10 | -0.0155157 |
| CDCP1 | CUB domain containing protein 1 | -0.0155086 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0151995 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0149884 |
| FERMT1 | fermitin family member 1 | -0.014577 |
| FOXP1 | forkhead box P1 | -0.014347 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0142173 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0140311 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0140062 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0139727 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.0138622 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.013567 |
| PHF14 | PHD finger protein 14 | -0.0135188 |
| XAF1 | XIAP associated factor 1 | -0.0134553 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0134307 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0132821 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0131607 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0131167 |
| OSMR | oncostatin M receptor | -0.0130826 |
| RPS2 | ribosomal protein S2 | -0.0129363 |
| RPS28 | ribosomal protein S28 | -0.0128441 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0127907 |
| HPCAL1 | hippocalcin-like 1 | -0.0127763 |
| RAD51B | RAD51 paralog B | -0.012687 |
| RPS21 | ribosomal protein S21 | -0.0126791 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0126737 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0124186 |
| RPL36A | ribosomal protein L36a | -0.0124096 |
