Fenofibrate_NCI-H1792 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Fenofibrate perturbation in NCI-H1792 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Fenofibrate_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FNDC3B fibronectin type III domain containing 3B 0.19176
PDE4D phosphodiesterase 4D, cAMP-specific 0.109112
SDK1 sidekick cell adhesion molecule 1 0.106516
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0889348
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0851349
FAM20C family with sequence similarity 20, member C 0.0804335
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0802919
SOD2 superoxide dismutase 2, mitochondrial 0.0798843
GRB10 growth factor receptor-bound protein 10 0.0761529
EFNA5 ephrin-A5 0.0755544
SMAD3 SMAD family member 3 0.075554
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0736466
VEGFA vascular endothelial growth factor A 0.0712739
NAV2 neuron navigator 2 0.0691124
CD44 CD44 molecule (Indian blood group) 0.0603908
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.0601281
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0578269
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0578223
AKAP13 A kinase (PRKA) anchor protein 13 0.0574529
DSCAM Down syndrome cell adhesion molecule 0.0566793
TRIO trio Rho guanine nucleotide exchange factor 0.0544509
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0543442
SIK3 SIK family kinase 3 0.0540625
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.0506273
ENO1 enolase 1, (alpha) 0.0502193
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.0491883
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0478778
ATXN1 ataxin 1 0.0463972
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.0448608
CXCL8 chemokine (C-X-C motif) ligand 8 0.0444547
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.0439324
RBM39 RNA binding motif protein 39 0.0432187
CDH13 cadherin 13 0.043218
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.042925
ELL2 elongation factor, RNA polymerase II, 2 0.0428279
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0425776
ANKRD11 ankyrin repeat domain 11 0.0420509
ARHGAP5 Rho GTPase activating protein 5 0.0410537
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0406473
OSMR oncostatin M receptor 0.0397676
SEPTIN9 septin 9 0.039476
FAM107B family with sequence similarity 107, member B 0.0393414
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0393335
RBMS3 RNA binding motif, single stranded interacting protein 3 0.0392019
MYH9 myosin, heavy chain 9, non-muscle 0.0387475
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0383235
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0382574
PRELID2 PRELI domain containing 2 0.0380072
UBC ubiquitin C 0.0376756
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.0376029
RPL3 ribosomal protein L3 0.0368968
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0355957
POTEF POTE ankyrin domain family, member F 0.0355533
EGFR epidermal growth factor receptor 0.0355117
AKAP12 A kinase (PRKA) anchor protein 12 0.0353007
RAB27B RAB27B, member RAS oncogene family 0.0352517
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0348871
ANKRD36 ankyrin repeat domain 36 0.0345304
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0342196
PTK2 protein tyrosine kinase 2 0.0341353
NPAS2 neuronal PAS domain protein 2 0.0339465
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.0338433
LDHA lactate dehydrogenase A 0.0335144
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0332746
TGM2 transglutaminase 2 0.0328299
PICALM phosphatidylinositol binding clathrin assembly protein 0.0327254
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.0321487
ZFAND3 zinc finger, AN1-type domain 3 0.0318286
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.0316319
PKM pyruvate kinase, muscle 0.0315106
MYO10 myosin X 0.0308594
LRMDA leucine rich melanocyte differentiation associated 0.0308392
APP amyloid beta (A4) precursor protein 0.0307462
DOCK5 dedicator of cytokinesis 5 0.0306876
TIMP1 TIMP metallopeptidase inhibitor 1 0.0305228
MEF2A myocyte enhancer factor 2A 0.0302579
ASPH aspartate beta-hydroxylase 0.0301289
TOP1 topoisomerase (DNA) I 0.0300616
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 0.0298398
ARHGAP32 Rho GTPase activating protein 32 0.0295342
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0292199
RPL4 ribosomal protein L4 0.0292084
HSPA8 heat shock 70kDa protein 8 0.0290756
IFI44L interferon-induced protein 44-like 0.0288535
KANSL1 KAT8 regulatory NSL complex subunit 1 0.0287825
NAV1 neuron navigator 1 0.0287455
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0286715
MSN moesin 0.0286448
MACF1 microtubule-actin crosslinking factor 1 0.0285224
ATP13A3 ATPase type 13A3 0.0284885
ASCC3 activating signal cointegrator 1 complex subunit 3 0.0283559
NPC1 Niemann-Pick disease, type C1 0.0282082
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0276652
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0275925
RAP1B RAP1B, member of RAS oncogene family 0.0275339
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 0.0274969
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0270361
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.027035
ACTN4 actinin, alpha 4 0.0270195
PELI1 pellino E3 ubiquitin protein ligase 1 0.0269635

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.173762
VIM vimentin -0.128929
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.122047
FTL ferritin, light polypeptide -0.0834015
IGFBP3 insulin-like growth factor binding protein 3 -0.0676744
PTMA prothymosin, alpha -0.0666345
TMSB10 thymosin beta 10 -0.0654326
BASP1 brain abundant, membrane attached signal protein 1 -0.0533398
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0530289
C15ORF48 chromosome 15 open reading frame 48 -0.0478643
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0458161
EGR1 early growth response 1 -0.0415151
BLZF1 basic leucine zipper nuclear factor 1 -0.0395831
ZMYND8 zinc finger, MYND-type containing 8 -0.0394674
EIF1 eukaryotic translation initiation factor 1 -0.0382447
LMAN1 lectin, mannose-binding, 1 -0.0368394
S100A6 S100 calcium binding protein A6 -0.0357831
IER3 immediate early response 3 -0.0354545
VDAC1 voltage-dependent anion channel 1 -0.0353864
RPLP1 ribosomal protein, large, P1 -0.0351994
KPNB1 karyopherin (importin) beta 1 -0.0338819
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0330587
DDIT3 DNA-damage-inducible transcript 3 -0.0328654
SOS1 son of sevenless homolog 1 (Drosophila) -0.0327592
LOX lysyl oxidase -0.0326004
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0325508
RPLP0 ribosomal protein, large, P0 -0.0323891
ARF4 ADP-ribosylation factor 4 -0.0317735
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0315442
PFN1 profilin 1 -0.0300576
SYAP1 synapse associated protein 1 -0.0294997
SRP54 signal recognition particle 54kDa -0.028773
SEC24A SEC24 family member A -0.0284197
SEC31A SEC31 homolog A (S. cerevisiae) -0.0282318
GCC2 GRIP and coiled-coil domain containing 2 -0.0280454
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -0.0279143
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0277411
GOLGA4 golgin A4 -0.027688
NCOA7 nuclear receptor coactivator 7 -0.0274652
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0270346
RPS21 ribosomal protein S21 -0.0268832
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0264377
WASF2 WAS protein family, member 2 -0.0262181
MT2A metallothionein 2A -0.0254699
RPS19 ribosomal protein S19 -0.025334
MYADM myeloid-associated differentiation marker -0.0250726
DPYD dihydropyrimidine dehydrogenase -0.0250414
ANKRD28 ankyrin repeat domain 28 -0.0247725
MORF4L2 mortality factor 4 like 2 -0.0243023
GSTP1 glutathione S-transferase pi 1 -0.0242485
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.0234959
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 -0.0230409
MRPS6 mitochondrial ribosomal protein S6 -0.0228822
TMEM263 transmembrane protein 263 -0.0225094
FOS FBJ murine osteosarcoma viral oncogene homolog -0.022446
KDM2A lysine (K)-specific demethylase 2A -0.0221996
BPTF bromodomain PHD finger transcription factor -0.0221141
RIOK3 RIO kinase 3 -0.0220332
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.021679
BTG1 B-cell translocation gene 1, anti-proliferative -0.0216039
RPL32 ribosomal protein L32 -0.0211861
PCBP2 poly(rC) binding protein 2 -0.0210251
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.0209844
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0206403
FKBP10 FK506 binding protein 10, 65 kDa -0.0206182
RAB7A RAB7A, member RAS oncogene family -0.0203313
MXI1 MAX interactor 1, dimerization protein -0.0201603
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -0.020147
AKAP9 A kinase (PRKA) anchor protein 9 -0.0198314
MBD5 methyl-CpG binding domain protein 5 -0.0197311
MYO9A myosin IXA -0.0196832
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -0.0196501
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0192751
HMGA1 high mobility group AT-hook 1 -0.0190608
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0190408
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -0.01862
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) -0.0185479
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0184508
RPL34 ribosomal protein L34 -0.0184472
FNBP4 formin binding protein 4 -0.0183522
HDAC9 histone deacetylase 9 -0.0182905
ZFP91 ZFP91 zinc finger protein -0.0181472
CCNI cyclin I -0.0181368
ARF1 ADP-ribosylation factor 1 -0.0180231
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.017953
TXNIP thioredoxin interacting protein -0.0179412
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0179036
CCDC88A coiled-coil domain containing 88A -0.0177085
UGP2 UDP-glucose pyrophosphorylase 2 -0.0176596
ARHGAP24 Rho GTPase activating protein 24 -0.0176012
CLINT1 clathrin interactor 1 -0.0174035
KLF6 Kruppel-like factor 6 -0.0173211
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0171482
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0170921
ZNF609 zinc finger protein 609 -0.0170708
SSH2 slingshot protein phosphatase 2 -0.0168705
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0168527
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0168494
PTPRK protein tyrosine phosphatase, receptor type, K -0.016809
SYT1 synaptotagmin I -0.0168013