| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fenofibrate perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fenofibrate_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.202624 |
| GRAMD1B | GRAM domain containing 1B | 0.14429 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0963553 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.091524 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0897596 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0797353 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0795885 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0759191 |
| RTN4 | reticulon 4 | 0.0724801 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0706256 |
| TPM3 | tropomyosin 3 | 0.0694086 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0594911 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0566064 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0556716 |
| USP3 | ubiquitin specific peptidase 3 | 0.0552194 |
| FGB | fibrinogen beta chain | 0.0550419 |
| CCNL1 | cyclin L1 | 0.0518946 |
| ZNF292 | zinc finger protein 292 | 0.0447581 |
| RPL3 | ribosomal protein L3 | 0.0437079 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0432632 |
| WDR43 | WD repeat domain 43 | 0.0430161 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0425572 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0424172 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0423112 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0418943 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0406472 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0390875 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0387358 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0387111 |
| YBX1 | Y box binding protein 1 | 0.0378582 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0378572 |
| NUP58 | nucleoporin 58 | 0.0368822 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0365396 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.036442 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0360743 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0360235 |
| RPL4 | ribosomal protein L4 | 0.0355608 |
| ANLN | anillin, actin binding protein | 0.03539 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0351681 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0348165 |
| CHN1 | chimerin 1 | 0.034077 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0338903 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0332974 |
| OLA1 | Obg-like ATPase 1 | 0.0329879 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0323313 |
| YBX3 | Y box binding protein 3 | 0.0314878 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.031356 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.0311864 |
| MKI67 | marker of proliferation Ki-67 | 0.0311613 |
| POTEF | POTE ankyrin domain family, member F | 0.0311035 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0307563 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0306822 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0302954 |
| TPD52 | tumor protein D52 | 0.0302489 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0299306 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0298662 |
| PFDN2 | prefoldin subunit 2 | 0.0297438 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0296969 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0296102 |
| CENPF | centromere protein F, 350/400kDa | 0.0295317 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0293805 |
| KIF23 | kinesin family member 23 | 0.0290066 |
| RBM39 | RNA binding motif protein 39 | 0.0285773 |
| WBP11 | WW domain binding protein 11 | 0.0282959 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0281515 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0280296 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0279861 |
| YME1L1 | YME1-like 1 ATPase | 0.0278645 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0277909 |
| HDGF | hepatoma-derived growth factor | 0.0277184 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0276123 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0275512 |
| RNF145 | ring finger protein 145 | 0.0273652 |
| FGG | fibrinogen gamma chain | 0.0272742 |
| MTMR3 | myotubularin related protein 3 | 0.0266802 |
| FAM168A | family with sequence similarity 168, member A | 0.0264341 |
| TPX2 | TPX2, microtubule-associated | 0.026167 |
| CALR | calreticulin | 0.0256188 |
| TAGLN2 | transgelin 2 | 0.025515 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0253302 |
| QKI | QKI, KH domain containing, RNA binding | 0.0253126 |
| ENAH | enabled homolog (Drosophila) | 0.0252424 |
| PFN1 | profilin 1 | 0.0251631 |
| SIN3A | SIN3 transcription regulator family member A | 0.0251003 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0249138 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0248041 |
| TMEM123 | transmembrane protein 123 | 0.0246639 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0246117 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0246061 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.024566 |
| PCBP2 | poly(rC) binding protein 2 | 0.0245434 |
| RHEB | Ras homolog enriched in brain | 0.0244624 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0244322 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0243587 |
| JAK1 | Janus kinase 1 | 0.0242301 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0241175 |
| MATR3 | matrin 3 | 0.0239678 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0237001 |
| PNN | pinin, desmosome associated protein | 0.0236933 |
| MORF4L1 | mortality factor 4 like 1 | 0.023481 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.162515 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.149851 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.149305 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.132515 |
| MT2A | metallothionein 2A | -0.122264 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.115211 |
| ACTG1 | actin gamma 1 | -0.110466 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.108486 |
| CMIP | c-Maf inducing protein | -0.108345 |
| VIM | vimentin | -0.0966924 |
| IER3 | immediate early response 3 | -0.0800364 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0796634 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0726829 |
| FMNL2 | formin-like 2 | -0.0708422 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0704374 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0696655 |
| EGFR | epidermal growth factor receptor | -0.0693059 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0665565 |
| FLNB | filamin B, beta | -0.0634164 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0604003 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0581923 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0581648 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0580471 |
| CAVIN1 | caveolae associated protein 1 | -0.0541437 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0539271 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0534526 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0521326 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0519813 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0517264 |
| GLIS3 | GLIS family zinc finger 3 | -0.0515485 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0506247 |
| PYGL | phosphorylase, glycogen, liver | -0.0490339 |
| MYO1E | myosin IE | -0.0480074 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0478177 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0456311 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0453319 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0453026 |
| INTS6 | integrator complex subunit 6 | -0.0450412 |
| ATXN1 | ataxin 1 | -0.0441442 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0434557 |
| PARD3 | par-3 family cell polarity regulator | -0.0426478 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0415348 |
| NEBL | nebulette | -0.0412517 |
| NDRG1 | N-myc downstream regulated 1 | -0.0406246 |
| RPL35A | ribosomal protein L35a | -0.0406101 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0391777 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.038725 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0381577 |
| DST | dystonin | -0.0377115 |
| RPS29 | ribosomal protein S29 | -0.0375492 |
| RPS8 | ribosomal protein S8 | -0.0368006 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0365492 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0362868 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0362076 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0361311 |
| NEGR1 | neuronal growth regulator 1 | -0.0361009 |
| HLA-B | major histocompatibility complex, class I, B | -0.0360553 |
| IGF2 | insulin-like growth factor 2 | -0.0358807 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0354154 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0350762 |
| EHBP1 | EH domain binding protein 1 | -0.0348245 |
| RAD51B | RAD51 paralog B | -0.0348078 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0340336 |
| RPL31 | ribosomal protein L31 | -0.0337163 |
| CTBP2 | C-terminal binding protein 2 | -0.0336389 |
| NF1 | neurofibromin 1 | -0.0331573 |
| CUX1 | cut-like homeobox 1 | -0.0330977 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0330081 |
| RPL37A | ribosomal protein L37a | -0.0330061 |
| PTMA | prothymosin, alpha | -0.0325843 |
| EFNA5 | ephrin-A5 | -0.0324889 |
| NUMB | numb homolog (Drosophila) | -0.0319745 |
| S100A10 | S100 calcium binding protein A10 | -0.0314855 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0313513 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0313155 |
| HMGA2 | high mobility group AT-hook 2 | -0.031188 |
| RPS27A | ribosomal protein S27a | -0.0308216 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0306986 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0306633 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.030647 |
| PCNX4 | pecanex 4 | -0.0304218 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0297591 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0296361 |
| NLK | nemo-like kinase | -0.0295938 |
| SNX14 | sorting nexin 14 | -0.0290966 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0286506 |
| VCL | vinculin | -0.0278393 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.027679 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0275004 |
| AHNAK | AHNAK nucleoprotein | -0.0274983 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0274544 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0272537 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.027171 |
| CDK13 | cyclin-dependent kinase 13 | -0.0270858 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0270838 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.026737 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0265606 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0263389 |
| LOXL2 | lysyl oxidase-like 2 | -0.0263225 |
| KYNU | kynureninase | -0.0263087 |
