| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fenofibrate perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fenofibrate_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.260354 |
| NDRG1 | N-myc downstream regulated 1 | 0.171535 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.143376 |
| KRT17 | keratin 17, type I | 0.130447 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.116914 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.103995 |
| EZR | ezrin | 0.103054 |
| VEGFA | vascular endothelial growth factor A | 0.100363 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0925395 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0923671 |
| FMN1 | formin 1 | 0.0874424 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0829471 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0816053 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0781824 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0773214 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0746101 |
| S100A9 | S100 calcium binding protein A9 | 0.0730551 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0662176 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0617871 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0606071 |
| LDHA | lactate dehydrogenase A | 0.0588577 |
| ENO1 | enolase 1, (alpha) | 0.0578554 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0578071 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0577209 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0569699 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0566026 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0562439 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.056116 |
| UBC | ubiquitin C | 0.0549746 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0535374 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0530055 |
| SLTM | SAFB-like, transcription modulator | 0.0526203 |
| MT2A | metallothionein 2A | 0.0494335 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0491873 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.048172 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0476682 |
| ACTN4 | actinin, alpha 4 | 0.0464187 |
| CNKSR3 | CNKSR family member 3 | 0.0457844 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0456712 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0449607 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0448311 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0444915 |
| MCL1 | myeloid cell leukemia 1 | 0.0436466 |
| PTMA | prothymosin, alpha | 0.0433666 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0429009 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0425973 |
| PTK2 | protein tyrosine kinase 2 | 0.0423573 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0421101 |
| FN1 | fibronectin 1 | 0.0411635 |
| H3-3B | H3.3 histone B | 0.0408541 |
| CD2AP | CD2-associated protein | 0.0406583 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0404069 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0403801 |
| EXOC6B | exocyst complex component 6B | 0.0401304 |
| SKAP1 | src kinase associated phosphoprotein 1 | 0.0399959 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0395618 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.039305 |
| FRMD4A | FERM domain containing 4A | 0.0391385 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0390068 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.038944 |
| RBM39 | RNA binding motif protein 39 | 0.0385018 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0384658 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0383556 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0382544 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0382049 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0377425 |
| ATP11A | ATPase, class VI, type 11A | 0.0376562 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0372162 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0369658 |
| RORA | RAR-related orphan receptor A | 0.0368181 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0354096 |
| RPS3 | ribosomal protein S3 | 0.0353632 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0352875 |
| ITGA6 | integrin, alpha 6 | 0.0350571 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0345292 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0344884 |
| FTL | ferritin, light polypeptide | 0.0344502 |
| CUX1 | cut-like homeobox 1 | 0.0340631 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.033549 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0333507 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0332552 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0326393 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0326065 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0324928 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0324288 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.032399 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0317422 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0317335 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0311481 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0308408 |
| FHIT | fragile histidine triad | 0.0307629 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0307249 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0303198 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0300297 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0299031 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0292855 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0289104 |
| S100A8 | S100 calcium binding protein A8 | 0.028756 |
| TPM3 | tropomyosin 3 | 0.0282791 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0282283 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.0999894 |
| NCOA3 | nuclear receptor coactivator 3 | -0.095221 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0924268 |
| MYO1E | myosin IE | -0.0806602 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0710881 |
| ANXA1 | annexin A1 | -0.0704711 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.066562 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0664776 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0648747 |
| RPLP0 | ribosomal protein, large, P0 | -0.062587 |
| MORF4L2 | mortality factor 4 like 2 | -0.0619514 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0612187 |
| EGFR | epidermal growth factor receptor | -0.0594071 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0592199 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.059124 |
| COPA | coatomer protein complex, subunit alpha | -0.0588033 |
| CDC73 | cell division cycle 73 | -0.058447 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.057869 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0571779 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0556715 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0545295 |
| ANXA2 | annexin A2 | -0.0544627 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0529686 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0525216 |
| HMGA1 | high mobility group AT-hook 1 | -0.0520312 |
| NPTN | neuroplastin | -0.0514753 |
| OXR1 | oxidation resistance 1 | -0.0506325 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0502619 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0501954 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0500746 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0496464 |
| SQSTM1 | sequestosome 1 | -0.0493016 |
| RCOR1 | REST corepressor 1 | -0.0489134 |
| PDE10A | phosphodiesterase 10A | -0.048908 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0488015 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0483397 |
| PHF21A | PHD finger protein 21A | -0.0482834 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0480297 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0464605 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0463413 |
| RPL23 | ribosomal protein L23 | -0.0459823 |
| SRPK2 | SRSF protein kinase 2 | -0.0451587 |
| TXNIP | thioredoxin interacting protein | -0.0449639 |
| CD44 | CD44 molecule (Indian blood group) | -0.0448176 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0446074 |
| RPL35A | ribosomal protein L35a | -0.0441544 |
| THOC2 | THO complex 2 | -0.0437302 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0428569 |
| CMIP | c-Maf inducing protein | -0.0426018 |
| XPO1 | exportin 1 | -0.042477 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0424528 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0422134 |
| GPC6 | glypican 6 | -0.0417433 |
| IGF2 | insulin-like growth factor 2 | -0.0415474 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0414382 |
| ATP11B | ATPase, class VI, type 11B | -0.0412213 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0406629 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0404305 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0399866 |
| CALR | calreticulin | -0.0397579 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0396447 |
| SP100 | SP100 nuclear antigen | -0.0393264 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0391357 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0391103 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0389338 |
| MYO6 | myosin VI | -0.0387708 |
| MED13 | mediator complex subunit 13 | -0.0387028 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0386523 |
| POTEF | POTE ankyrin domain family, member F | -0.0385326 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0384474 |
| SETD2 | SET domain containing 2 | -0.0381491 |
| VCL | vinculin | -0.0380157 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0375312 |
| ANO6 | anoctamin 6 | -0.037483 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0371356 |
| LAMC2 | laminin, gamma 2 | -0.0369993 |
| RPL11 | ribosomal protein L11 | -0.0369691 |
| ARF4 | ADP-ribosylation factor 4 | -0.03679 |
| YAP1 | Yes-associated protein 1 | -0.035475 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0352884 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0351366 |
| SEPTIN2 | septin 2 | -0.0348027 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0345656 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0340628 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0338703 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0338583 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.033801 |
| HLA-B | major histocompatibility complex, class I, B | -0.0330777 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0329299 |
| FOXP1 | forkhead box P1 | -0.0327968 |
| MED13L | mediator complex subunit 13-like | -0.032443 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0322239 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0321349 |
| YME1L1 | YME1-like 1 ATPase | -0.0319206 |
| CALU | calumenin | -0.0312271 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0306159 |
| TNPO1 | transportin 1 | -0.0306092 |
| MATR3 | matrin 3 | -0.0305354 |
| S100A10 | S100 calcium binding protein A10 | -0.0303722 |
| RUNX1 | runt-related transcription factor 1 | -0.0302962 |
