| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fenofibrate perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fenofibrate_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.192898 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.126477 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.119491 |
| PEG10 | paternally expressed 10 | 0.100372 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.096889 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0914171 |
| PTMA | prothymosin, alpha | 0.0849198 |
| TMSB4X | thymosin beta 4, X-linked | 0.0848096 |
| THBS1 | thrombospondin 1 | 0.0831838 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0822884 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0810068 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0741476 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0720401 |
| CENPF | centromere protein F, 350/400kDa | 0.0706665 |
| RBM39 | RNA binding motif protein 39 | 0.0680038 |
| ZNF292 | zinc finger protein 292 | 0.0675085 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0646478 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0644084 |
| NCKAP1 | NCK-associated protein 1 | 0.0622154 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0615635 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.060374 |
| HMGB2 | high mobility group box 2 | 0.0601453 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0589111 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.058012 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0576885 |
| CALR | calreticulin | 0.0570743 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0567145 |
| XPO1 | exportin 1 | 0.0547347 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0532864 |
| RTN4 | reticulon 4 | 0.0526864 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0509879 |
| H1-0 | H1.0 linker histone | 0.0504928 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0502388 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0494395 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0489981 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.048841 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0483332 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0483058 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0477402 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0475695 |
| DST | dystonin | 0.0473441 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.046529 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0465119 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0462967 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0447366 |
| PUM1 | pumilio RNA-binding family member 1 | 0.044606 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0438384 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0437904 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0434716 |
| RAI1 | retinoic acid induced 1 | 0.0432946 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0431425 |
| FAT1 | FAT atypical cadherin 1 | 0.0429036 |
| EMP1 | epithelial membrane protein 1 | 0.0428269 |
| RPL3 | ribosomal protein L3 | 0.0427251 |
| RPL4 | ribosomal protein L4 | 0.039998 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0399802 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0398788 |
| PRELID2 | PRELI domain containing 2 | 0.0392072 |
| COL5A2 | collagen, type V, alpha 2 | 0.038938 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.038788 |
| TPX2 | TPX2, microtubule-associated | 0.0381965 |
| OGA | O-GlcNAcase | 0.0375885 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0375402 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0374133 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0373788 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0372979 |
| RHEB | Ras homolog enriched in brain | 0.0371338 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0369869 |
| ANXA1 | annexin A1 | 0.0362821 |
| NFIA | nuclear factor I/A | 0.0362531 |
| ECT2 | epithelial cell transforming 2 | 0.0361552 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0360537 |
| YBX1 | Y box binding protein 1 | 0.036009 |
| GOLGA4 | golgin A4 | 0.0357137 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0355577 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0351386 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0347061 |
| THOC2 | THO complex 2 | 0.0343939 |
| CANX | calnexin | 0.0342958 |
| CENPE | centromere protein E, 312kDa | 0.0341633 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0341164 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0340974 |
| ACTN4 | actinin, alpha 4 | 0.0340642 |
| MKI67 | marker of proliferation Ki-67 | 0.0338383 |
| JMJD1C | jumonji domain containing 1C | 0.0338003 |
| PLPP1 | phospholipid phosphatase 1 | 0.0334522 |
| ATG5 | autophagy related 5 | 0.0331726 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0330635 |
| APP | amyloid beta (A4) precursor protein | 0.032664 |
| SEPTIN7 | septin 7 | 0.0321978 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0321378 |
| NUP58 | nucleoporin 58 | 0.0321223 |
| CCNL1 | cyclin L1 | 0.0320909 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0320675 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0320504 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0319604 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0317341 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0316486 |
| RPN2 | ribophorin II | 0.0315719 |
| ZFR | zinc finger RNA binding protein | 0.0315501 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.1635 |
| CADM2 | cell adhesion molecule 2 | -0.129223 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.102278 |
| PCDH9 | protocadherin 9 | -0.0826719 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0691349 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0638651 |
| TMSB10 | thymosin beta 10 | -0.0636002 |
| CDH19 | cadherin 19, type 2 | -0.0559634 |
| RASAL2 | RAS protein activator like 2 | -0.0509836 |
| VIM | vimentin | -0.0507071 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.048996 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0466251 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.043757 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0426642 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0420184 |
| GNAS | GNAS complex locus | -0.0405083 |
| RPLP1 | ribosomal protein, large, P1 | -0.0382345 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0364381 |
| FOXP2 | forkhead box P2 | -0.0363074 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0357867 |
| RPL35A | ribosomal protein L35a | -0.0352626 |
| FST | follistatin | -0.0346814 |
| RPS16 | ribosomal protein S16 | -0.0345665 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0325412 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0322173 |
| APOE | apolipoprotein E | -0.0317263 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0311776 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0305704 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0305097 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0301978 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0296401 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0294009 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0290264 |
| RAD51B | RAD51 paralog B | -0.0287138 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0283928 |
| RPL23 | ribosomal protein L23 | -0.0278421 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0277762 |
| FTL | ferritin, light polypeptide | -0.0274324 |
| LRRC4C | leucine rich repeat containing 4C | -0.0272131 |
| MT2A | metallothionein 2A | -0.0270606 |
| RPS8 | ribosomal protein S8 | -0.0266609 |
| RPL37A | ribosomal protein L37a | -0.026424 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0260751 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0257105 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0252908 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0252006 |
| RPL30 | ribosomal protein L30 | -0.0249932 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0247591 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0245119 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0245112 |
| RPS25 | ribosomal protein S25 | -0.024273 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0242382 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0239017 |
| MEIS2 | Meis homeobox 2 | -0.0236488 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0234633 |
| SCFD1 | sec1 family domain containing 1 | -0.0233791 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0228391 |
| RPL26 | ribosomal protein L26 | -0.0226571 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0224417 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0222862 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0222446 |
| RPLP0 | ribosomal protein, large, P0 | -0.0219414 |
| RPL31 | ribosomal protein L31 | -0.0218365 |
| FN1 | fibronectin 1 | -0.0214862 |
| ARLN | allregulin | -0.0213417 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0212865 |
| UBAP2 | ubiquitin associated protein 2 | -0.0212655 |
| ZFHX4 | zinc finger homeobox 4 | -0.0208854 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 | -0.0207608 |
| RPS19 | ribosomal protein S19 | -0.0203365 |
| RPS6 | ribosomal protein S6 | -0.0201699 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0198702 |
| HMGA2 | high mobility group AT-hook 2 | -0.0196312 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0192426 |
| FOXO1 | forkhead box O1 | -0.0191624 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0191613 |
| LUZP2 | leucine zipper protein 2 | -0.0191342 |
| RPS15 | ribosomal protein S15 | -0.0189827 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0189011 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0188543 |
| PALLD | palladin, cytoskeletal associated protein | -0.0187504 |
| ACACA | acetyl-CoA carboxylase alpha | -0.01854 |
| RPS27A | ribosomal protein S27a | -0.0183766 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | -0.0182478 |
| ANK2 | ankyrin 2, neuronal | -0.0182318 |
| SNX6 | sorting nexin 6 | -0.018198 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0181101 |
| RCOR1 | REST corepressor 1 | -0.0176812 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0176716 |
| CNTN6 | contactin 6 | -0.0175751 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0174445 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0173133 |
| RPL34 | ribosomal protein L34 | -0.0172079 |
| RPL11 | ribosomal protein L11 | -0.0172025 |
| AHI1 | Abelson helper integration site 1 | -0.0171893 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0171787 |
| PCDH7 | protocadherin 7 | -0.017143 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | -0.0170979 |
| SIK2 | salt-inducible kinase 2 | -0.0170887 |
| PBRM1 | polybromo 1 | -0.0170172 |
