| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fenofibrate perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fenofibrate_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.12516 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.110561 |
| PKM | pyruvate kinase, muscle | 0.0953926 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0780437 |
| FLNB | filamin B, beta | 0.0774034 |
| ECT2 | epithelial cell transforming 2 | 0.0623208 |
| EZR | ezrin | 0.0607447 |
| PDGFC | platelet derived growth factor C | 0.0551022 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0508061 |
| ZNF292 | zinc finger protein 292 | 0.0494495 |
| CCNL1 | cyclin L1 | 0.0487579 |
| YAP1 | Yes-associated protein 1 | 0.0463919 |
| UBC | ubiquitin C | 0.0456254 |
| RTN4 | reticulon 4 | 0.0449775 |
| RPL3 | ribosomal protein L3 | 0.0440408 |
| TMSB4X | thymosin beta 4, X-linked | 0.0436782 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0428509 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0426284 |
| SQSTM1 | sequestosome 1 | 0.0403644 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0393952 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0390838 |
| RHOA | ras homolog family member A | 0.0390039 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0385064 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0383 |
| DSCAM | Down syndrome cell adhesion molecule | 0.03814 |
| QKI | QKI, KH domain containing, RNA binding | 0.037228 |
| PRELID2 | PRELI domain containing 2 | 0.0362321 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0361658 |
| OGA | O-GlcNAcase | 0.0361281 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0358609 |
| TXNIP | thioredoxin interacting protein | 0.034523 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0344812 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0343409 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0340402 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.034007 |
| ZNF608 | zinc finger protein 608 | 0.0338949 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0335898 |
| CUL3 | cullin 3 | 0.0335514 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0335113 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0334032 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0327276 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0324681 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.03242 |
| PLPP3 | phospholipid phosphatase 3 | 0.0322094 |
| AHNAK | AHNAK nucleoprotein | 0.0316674 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0315765 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0313067 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0311395 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0307728 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0302508 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0299129 |
| OLA1 | Obg-like ATPase 1 | 0.0298745 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0297478 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0294587 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0292934 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0285861 |
| APP | amyloid beta (A4) precursor protein | 0.0283062 |
| RBM39 | RNA binding motif protein 39 | 0.0282822 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0281891 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0281709 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0279559 |
| POTEF | POTE ankyrin domain family, member F | 0.0276504 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0269806 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0268486 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0268315 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0266123 |
| PTK2 | protein tyrosine kinase 2 | 0.0264572 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0256081 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.025578 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0255061 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0254508 |
| TFG | TRK-fused gene | 0.0247412 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0245558 |
| YEATS2 | YEATS domain containing 2 | 0.0243269 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0243018 |
| YTHDC1 | YTH domain containing 1 | 0.0242838 |
| VMP1 | vacuole membrane protein 1 | 0.0242558 |
| TLK2 | tousled-like kinase 2 | 0.0241575 |
| TPR | translocated promoter region, nuclear basket protein | 0.0240696 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0240436 |
| RBM25 | RNA binding motif protein 25 | 0.023927 |
| SRPK2 | SRSF protein kinase 2 | 0.0238364 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.023614 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0235435 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.023538 |
| ADAR | adenosine deaminase, RNA-specific | 0.0235052 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0234658 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0234557 |
| NBAS | neuroblastoma amplified sequence | 0.0234064 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0232256 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0232017 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0231843 |
| USP24 | ubiquitin specific peptidase 24 | 0.022972 |
| USP34 | ubiquitin specific peptidase 34 | 0.0229472 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0229259 |
| SFTPA2 | surfactant protein A2 | 0.0226798 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0226343 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.022631 |
| MACROD2 | MACRO domain containing 2 | 0.0225125 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0223949 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.153557 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.145499 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.141031 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.134922 |
| FOXP1 | forkhead box P1 | -0.105584 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0929598 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0663918 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0655158 |
| PTMA | prothymosin, alpha | -0.0556115 |
| BPTF | bromodomain PHD finger transcription factor | -0.0460433 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0437566 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.042561 |
| BMP10 | bone morphogenetic protein 10 | -0.0418019 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0399101 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0397796 |
| VCL | vinculin | -0.0395471 |
| PDE7B | phosphodiesterase 7B | -0.0382787 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0378396 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0369734 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0350256 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0349232 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0345553 |
| ZNF438 | zinc finger protein 438 | -0.0338011 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0335533 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.032709 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0311169 |
| CUX1 | cut-like homeobox 1 | -0.030936 |
| GLI3 | GLI family zinc finger 3 | -0.0305269 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0294639 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0292772 |
| RPLP0 | ribosomal protein, large, P0 | -0.0283093 |
| EGFR | epidermal growth factor receptor | -0.0262867 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0255054 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0253185 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0251323 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0250496 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0249502 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0247154 |
| MTAP | methylthioadenosine phosphorylase | -0.0246211 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0240534 |
| MLIP | muscular LMNA-interacting protein | -0.0239724 |
| PRSS23 | protease, serine, 23 | -0.0232453 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0231988 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0228199 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0225527 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0225361 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.022199 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0214865 |
| NEBL | nebulette | -0.0214497 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0203753 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0202865 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.020094 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0200525 |
| RPL7A | ribosomal protein L7a | -0.0200045 |
| MTDH | metadherin | -0.0199848 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0199047 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0198488 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0197838 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0196477 |
| S100A6 | S100 calcium binding protein A6 | -0.0196156 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0188559 |
| PLCE1 | phospholipase C, epsilon 1 | -0.0188076 |
| COMMD10 | COMM domain containing 10 | -0.0182196 |
| AEBP2 | AE binding protein 2 | -0.0182174 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0180107 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0178981 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0178556 |
| S100A4 | S100 calcium binding protein A4 | -0.0178304 |
| RIGI | RNA sensor RIG-I | -0.0177384 |
| RPL7 | ribosomal protein L7 | -0.0175366 |
| RPL12 | ribosomal protein L12 | -0.0174535 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0174427 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0173989 |
| BCL2 | B-cell CLL/lymphoma 2 | -0.0172305 |
| CTIF | CBP80/20-dependent translation initiation factor | -0.01702 |
| PFN1 | profilin 1 | -0.017019 |
| KIF5B | kinesin family member 5B | -0.0169994 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.0168828 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.016876 |
| PKP4 | plakophilin 4 | -0.0168433 |
| ONECUT2 | one cut homeobox 2 | -0.016828 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0167055 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0166944 |
| JMJD1C | jumonji domain containing 1C | -0.0166385 |
| LIMD1 | LIM domains containing 1 | -0.0165797 |
| NBEA | neurobeachin | -0.0165741 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0164786 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0164415 |
| PWWP2A | PWWP domain containing 2A | -0.0163942 |
| RYR2 | ryanodine receptor 2 (cardiac) | -0.0163114 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0162612 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0162367 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0160508 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0160114 |
| AHI1 | Abelson helper integration site 1 | -0.015976 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | -0.015661 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0155798 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0155343 |
| RBM8A | RNA binding motif protein 8A | -0.015476 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -0.0154754 |