| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| Description | A benzazepine that has formula C16H16ClNO3. (Chemical Entities of Biological Interest Ontology, CHEBI_5002) |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/3341 |
| Similar Terms | |
| Downloads & Tools |
200 proteins with high or low expression in Fenoldopam relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPAT4 | glycerol-3-phosphate acyltransferase 4 | 0.93 |
| HMOX1 | heme oxygenase 1 | 0.75 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.71 |
| TRAF3IP2 | TRAF3 interacting protein 2 | 0.6 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.59 |
| TTPA | tocopherol (alpha) transfer protein | 0.59 |
| FBXO41 | F-box protein 41 | 0.56 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | 0.55 |
| EID2 | EP300 interacting inhibitor of differentiation 2 | 0.51 |
| SNAP91 | synaptosomal-associated protein, 91kDa | 0.47 |
| ZNF624 | zinc finger protein 624 | 0.47 |
| SGMS2 | sphingomyelin synthase 2 | 0.45 |
| FJX1 | four jointed box 1 (Drosophila) | 0.45 |
| LIX1L | Lix1 homolog (chicken) like | 0.44 |
| FBXL15 | F-box and leucine-rich repeat protein 15 | 0.44 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.43 |
| FLYWCH1 | FLYWCH-type zinc finger 1 | 0.43 |
| IREB2 | iron-responsive element binding protein 2 | 0.43 |
| CMPK2 | cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial | 0.42 |
| KCTD17 | potassium channel tetramerization domain containing 17 | 0.42 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.42 |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.4 |
| ZFP30 | ZFP30 zinc finger protein | 0.4 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | 0.39 |
| ATXN1L | ataxin 1-like | 0.39 |
| ASTE1 | asteroid homolog 1 (Drosophila) | 0.38 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.38 |
| GPR161 | G protein-coupled receptor 161 | 0.38 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 | 0.36 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 0.35 |
| NCKAP5L | NCK-associated protein 5-like | 0.35 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B | 0.35 |
| PCSK9 | proprotein convertase subtilisin/kexin type 9 | 0.35 |
| SGO1 | shugoshin 1 | 0.35 |
| AASDH | aminoadipate-semialdehyde dehydrogenase | 0.34 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 | 0.34 |
| ZNF618 | zinc finger protein 618 | 0.34 |
| RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing | 0.34 |
| MKX | mohawk homeobox | 0.33 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | 0.33 |
| RNF138 | ring finger protein 138, E3 ubiquitin protein ligase | 0.33 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.33 |
| UBXN2A | UBX domain protein 2A | 0.32 |
| TTN | titin | 0.32 |
| SUSD2 | sushi domain containing 2 | 0.32 |
| UTP14C | UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) | 0.31 |
| ZNF320 | zinc finger protein 320 | 0.31 |
| RP9 | retinitis pigmentosa 9 (autosomal dominant) | 0.31 |
| UTP23 | UTP23, small subunit (SSU) processome component, homolog (yeast) | 0.31 |
| ADAM22 | ADAM metallopeptidase domain 22 | 0.31 |
| HEXD | hexosaminidase D | 0.31 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | 0.31 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.3 |
| EYS | eyes shut homolog (Drosophila) | 0.3 |
| BMP8A | bone morphogenetic protein 8a | 0.3 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.3 |
| H3C1 | H3 clustered histone 1 | 0.3 |
| ANKRD10 | ankyrin repeat domain 10 | 0.29 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 | 0.29 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | 0.29 |
| RPGR | retinitis pigmentosa GTPase regulator | 0.29 |
| FAM241B | family with sequence similarity 241 member B | 0.29 |
| MNT | MAX network transcriptional repressor | 0.28 |
| ADM | adrenomedullin | 0.28 |
| TRAK2 | trafficking protein, kinesin binding 2 | 0.28 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.28 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.28 |
| STK40 | serine/threonine kinase 40 | 0.27 |
| DEPDC1 | DEP domain containing 1 | 0.27 |
| N4BP3 | NEDD4 binding protein 3 | 0.27 |
| DUS4L | dihydrouridine synthase 4-like (S. cerevisiae) | 0.27 |
| COL6A3 | collagen, type VI, alpha 3 | 0.27 |
| FICD | FIC domain containing | 0.27 |
| GPATCH3 | G patch domain containing 3 | 0.27 |
| DCLRE1A | DNA cross-link repair 1A | 0.27 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.26 |
| DNAAF2 | dynein, axonemal, assembly factor 2 | 0.26 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | 0.26 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.26 |
| TYW1 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) | 0.26 |
| MRPS24 | mitochondrial ribosomal protein S24 | 0.26 |
| HPSE | heparanase | 0.26 |
| JMJD4 | jumonji domain containing 4 | 0.26 |
| HELB | helicase (DNA) B | 0.26 |
| NOVA2 | neuro-oncological ventral antigen 2 | 0.26 |
| RAD54L | RAD54-like (S. cerevisiae) | 0.26 |
| SORT1 | sortilin 1 | 0.26 |
| DAPK2 | death-associated protein kinase 2 | 0.26 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.25 |
| MED10 | mediator complex subunit 10 | 0.25 |
| ZNF485 | zinc finger protein 485 | 0.25 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.25 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.25 |
| DOCK11 | dedicator of cytokinesis 11 | 0.25 |
| TXNDC16 | thioredoxin domain containing 16 | 0.25 |
| BMP4 | bone morphogenetic protein 4 | 0.25 |
| ZBED8 | zinc finger, BED-type containing 8 | 0.25 |
| GABPB2 | GA binding protein transcription factor, beta subunit 2 | 0.24 |
| ERVMER34-1 | endogenous retrovirus group MER34, member 1 | 0.24 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.24 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FGB | fibrinogen beta chain | -1.04 |
| HSP90AB4P | heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene | -0.98 |
| ADCK1 | aarF domain containing kinase 1 | -0.71 |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 | -0.67 |
| USP27X | ubiquitin specific peptidase 27, X-linked | -0.66 |
| HSP90AB3P | heat shock protein 90kDa alpha (cytosolic), class B member 3, pseudogene | -0.61 |
| AASS | aminoadipate-semialdehyde synthase | -0.6 |
| CENPO | centromere protein O | -0.58 |
| PLEKHN1 | pleckstrin homology domain containing, family N member 1 | -0.57 |
| RUSC2 | RUN and SH3 domain containing 2 | -0.56 |
| PIP4P2 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 | -0.54 |
| DAP | death-associated protein | -0.49 |
| FN1 | fibronectin 1 | -0.49 |
| ABLIM2 | actin binding LIM protein family, member 2 | -0.48 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.47 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | -0.47 |
| TMSB10 | thymosin beta 10 | -0.45 |
| ANO8 | anoctamin 8 | -0.45 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.45 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.43 |
| CPN1 | carboxypeptidase N, polypeptide 1 | -0.43 |
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 | -0.43 |
| ONECUT2 | one cut homeobox 2 | -0.43 |
| ERCC6 | excision repair cross-complementation group 6 | -0.41 |
| COL1A1 | collagen, type I, alpha 1 | -0.4 |
| TC2N | tandem C2 domains, nuclear | -0.4 |
| TMC4 | transmembrane channel-like 4 | -0.39 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa | -0.38 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.37 |
| MYO15A | myosin XVA | -0.37 |
| LYPD3 | LY6/PLAUR domain containing 3 | -0.36 |
| RNF220 | ring finger protein 220 | -0.36 |
| SYTL2 | synaptotagmin-like 2 | -0.36 |
| MROH6 | maestro heat-like repeat family member 6 | -0.35 |
| FAAH | fatty acid amide hydrolase | -0.35 |
| ZNF524 | zinc finger protein 524 | -0.34 |
| CLCN3 | chloride channel, voltage-sensitive 3 | -0.34 |
| EIF3C | eukaryotic translation initiation factor 3, subunit C | -0.34 |
| SLC44A2 | solute carrier family 44 (choline transporter), member 2 | -0.34 |
| HBA1 | hemoglobin, alpha 1 | -0.34 |
| KLHL20 | kelch-like family member 20 | -0.34 |
| SPCS1 | signal peptidase complex subunit 1 homolog (S. cerevisiae) | -0.34 |
| REPS2 | RALBP1 associated Eps domain containing 2 | -0.33 |
| MEX3C | mex-3 RNA binding family member C | -0.33 |
| TMC5 | transmembrane channel-like 5 | -0.33 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.33 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.33 |
| AMDHD1 | amidohydrolase domain containing 1 | -0.33 |
| NUCB2 | nucleobindin 2 | -0.33 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.32 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 | -0.32 |
| TFCP2L1 | transcription factor CP2-like 1 | -0.32 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.31 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.31 |
| PLEK | pleckstrin | -0.3 |
| MRPS18C | mitochondrial ribosomal protein S18C | -0.3 |
| GPAA1 | glycosylphosphatidylinositol anchor attachment 1 | -0.3 |
| NHLRC3 | NHL repeat containing 3 | -0.29 |
| ZNF518B | zinc finger protein 518B | -0.29 |
| BOLA1 | bolA family member 1 | -0.29 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -0.29 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 | -0.28 |
| USP48 | ubiquitin specific peptidase 48 | -0.28 |
| VWA5B2 | von Willebrand factor A domain containing 5B2 | -0.28 |
| NLRC3 | NLR family, CARD domain containing 3 | -0.27 |
| ADIRF | adipogenesis regulatory factor | -0.27 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 | -0.27 |
| CEP85L | centrosomal protein 85kDa-like | -0.27 |
| SARDH | sarcosine dehydrogenase | -0.27 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.27 |
| CDC26 | cell division cycle 26 | -0.26 |
| ADSS1 | adenylosuccinate synthase 1 | -0.26 |
| ACAP3 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 | -0.26 |
| MANEA | mannosidase, endo-alpha | -0.26 |
| CLGN | calmegin | -0.26 |
| TPGS2 | tubulin polyglutamylase complex subunit 2 | -0.26 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.26 |
| GGT7 | gamma-glutamyltransferase 7 | -0.26 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | -0.26 |
| CCDC167 | coiled-coil domain containing 167 | -0.25 |
| C6ORF141 | chromosome 6 open reading frame 141 | -0.25 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | -0.25 |
| MT1F | metallothionein 1F | -0.25 |
| LMAN2 | lectin, mannose-binding 2 | -0.25 |
| LOXL2 | lysyl oxidase-like 2 | -0.25 |
| BCLAF3 | BCLAF1 and THRAP3 family member 3 | -0.25 |
| LASP1 | LIM and SH3 protein 1 | -0.24 |
| CEP44 | centrosomal protein 44kDa | -0.24 |
| CCDC9B | coiled-coil domain containing 9B | -0.24 |
| ABHD14A | abhydrolase domain containing 14A | -0.24 |
| ABHD4 | abhydrolase domain containing 4 | -0.24 |
| FAM185A | family with sequence similarity 185, member A | -0.24 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -0.24 |
| USP43 | ubiquitin specific peptidase 43 | -0.24 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.24 |
| SDHAF4 | succinate dehydrogenase complex assembly factor 4 | -0.24 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.24 |
| ZNF22 | zinc finger protein 22 | -0.24 |
| USP19 | ubiquitin specific peptidase 19 | -0.24 |
| CES3 | carboxylesterase 3 | -0.23 |
