Fertilization Gene Set

Dataset Reactome Pathways 2014
Category structural or functional annotations
Type pathway
Description The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). (Gene Ontology, GO_0009566)
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-1187000
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Genes

26 proteins participating in the Fertilization pathway from the Reactome Pathways dataset.

Symbol Name
ACR acrosin
ADAM2 ADAM metallopeptidase domain 2
ADAM20 ADAM metallopeptidase domain 20
ADAM21 ADAM metallopeptidase domain 21
ADAM30 ADAM metallopeptidase domain 30
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
CATSPER1 cation channel, sperm associated 1
CATSPER2 cation channel, sperm associated 2
CATSPER3 cation channel, sperm associated 3
CATSPER4 cation channel, sperm associated 4
CATSPERB catsper channel auxiliary subunit beta
CATSPERD catsper channel auxiliary subunit delta
CATSPERG catsper channel auxiliary subunit gamma
CD9 CD9 molecule
HVCN1 hydrogen voltage gated channel 1
IZUMO1 izumo sperm-egg fusion 1
IZUMO2 IZUMO family member 2
IZUMO3 IZUMO family member 3
IZUMO4 IZUMO family member 4
KCNU1 potassium channel, subfamily U, member 1
OVGP1 oviductal glycoprotein 1, 120kDa
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
ZP1 zona pellucida glycoprotein 1 (sperm receptor)
ZP2 zona pellucida glycoprotein 2 (sperm receptor)
ZP3 zona pellucida glycoprotein 3 (sperm receptor)
ZP4 zona pellucida glycoprotein 4