| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ferulic acid perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ferulic acid_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.193012 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.124774 |
| SMAD3 | SMAD family member 3 | 0.0922041 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.090883 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0897107 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0846328 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.0846032 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0836956 |
| NRP2 | neuropilin 2 | 0.0815277 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0801938 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0795074 |
| G0S2 | G0/G1 switch 2 | 0.0743467 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0741348 |
| FAT1 | FAT atypical cadherin 1 | 0.0734798 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0732346 |
| MSN | moesin | 0.0711473 |
| FLNA | filamin A, alpha | 0.0663266 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0649952 |
| APP | amyloid beta (A4) precursor protein | 0.0620974 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0615595 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0594278 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0569743 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0563462 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0560848 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0542052 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0528583 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0522772 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0522709 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0520341 |
| VEGFA | vascular endothelial growth factor A | 0.0512171 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0507296 |
| DENND2B | DENN domain containing 2B | 0.0497503 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0483781 |
| PLEC | plectin | 0.0475665 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0467397 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0466022 |
| ARRDC3 | arrestin domain containing 3 | 0.0462256 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0457983 |
| RUNX1 | runt-related transcription factor 1 | 0.0451085 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0443029 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0436585 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.0436436 |
| ANKRD11 | ankyrin repeat domain 11 | 0.04364 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0432673 |
| ANKRD10 | ankyrin repeat domain 10 | 0.042311 |
| CD44 | CD44 molecule (Indian blood group) | 0.042048 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0414805 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0413125 |
| GPC6 | glypican 6 | 0.0410655 |
| RPL3 | ribosomal protein L3 | 0.0408699 |
| SEPTIN9 | septin 9 | 0.0398498 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0394205 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0393585 |
| POTEF | POTE ankyrin domain family, member F | 0.0392107 |
| PAX8 | paired box 8 | 0.0378641 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0376094 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0373683 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.0369692 |
| TPM3 | tropomyosin 3 | 0.0368683 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.036568 |
| IRS2 | insulin receptor substrate 2 | 0.0360645 |
| TGFB2 | transforming growth factor, beta 2 | 0.0359809 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | 0.0346422 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0346363 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0337087 |
| NAV2 | neuron navigator 2 | 0.0337027 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0333983 |
| PLK2 | polo-like kinase 2 | 0.03323 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0330777 |
| SP3 | Sp3 transcription factor | 0.033 |
| ANLN | anillin, actin binding protein | 0.0328604 |
| HPCAL1 | hippocalcin-like 1 | 0.0327836 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0327031 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0323072 |
| ACTN4 | actinin, alpha 4 | 0.0322036 |
| CADM1 | cell adhesion molecule 1 | 0.0321498 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.032119 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0319413 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0314678 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0310565 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0310433 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0304707 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0301842 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0301624 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0298497 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0298497 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0297664 |
| FLNB | filamin B, beta | 0.0296195 |
| TXNRD1 | thioredoxin reductase 1 | 0.0294844 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0294462 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0293742 |
| ATP13A3 | ATPase type 13A3 | 0.0293517 |
| CENPF | centromere protein F, 350/400kDa | 0.0286263 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0285006 |
| PTK2 | protein tyrosine kinase 2 | 0.0284979 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0283552 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0283317 |
| MYO10 | myosin X | 0.0282906 |
| JAK1 | Janus kinase 1 | 0.0279021 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0278946 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.227552 |
| FRMD4A | FERM domain containing 4A | -0.167079 |
| VIM | vimentin | -0.150049 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.108907 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0984343 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0915037 |
| CP | ceruloplasmin (ferroxidase) | -0.0766228 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.061833 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0582752 |
| CTSD | cathepsin D | -0.0463353 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0439552 |
| HLA-B | major histocompatibility complex, class I, B | -0.0433216 |
| TMSB10 | thymosin beta 10 | -0.0426974 |
| PLIN2 | perilipin 2 | -0.0416663 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0404975 |
| FTL | ferritin, light polypeptide | -0.0382168 |
| SP100 | SP100 nuclear antigen | -0.0381931 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0376091 |
| RIGI | RNA sensor RIG-I | -0.0371021 |
| HLA-E | major histocompatibility complex, class I, E | -0.0360391 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0355592 |
| CA12 | carbonic anhydrase XII | -0.0345596 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0340761 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.032034 |
| RRBP1 | ribosome binding protein 1 | -0.0315045 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0312939 |
| MTDH | metadherin | -0.0312819 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0308481 |
| RAI14 | retinoic acid induced 14 | -0.0302637 |
| MMP7 | matrix metallopeptidase 7 | -0.029588 |
| EHBP1 | EH domain binding protein 1 | -0.0286585 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0284458 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0284241 |
| S100A6 | S100 calcium binding protein A6 | -0.0283851 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.028115 |
| APOL1 | apolipoprotein L, 1 | -0.0279479 |
| RPL35A | ribosomal protein L35a | -0.0274644 |
| PRKCA | protein kinase C, alpha | -0.026782 |
| CAVIN1 | caveolae associated protein 1 | -0.0266813 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.026408 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0262945 |
| VCL | vinculin | -0.0262716 |
| IFI44L | interferon-induced protein 44-like | -0.0259147 |
| HLA-C | major histocompatibility complex, class I, C | -0.0256965 |
| GOLGB1 | golgin B1 | -0.025151 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0250029 |
| HLA-A | major histocompatibility complex, class I, A | -0.0249898 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0245255 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0243815 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0243536 |
| UBC | ubiquitin C | -0.0241263 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0234966 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0234022 |
| INTS6 | integrator complex subunit 6 | -0.0233266 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.023192 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0230719 |
| TPM4 | tropomyosin 4 | -0.0226462 |
| RPS6 | ribosomal protein S6 | -0.0225053 |
| CUX1 | cut-like homeobox 1 | -0.0224635 |
| XAF1 | XIAP associated factor 1 | -0.021918 |
| RPL34 | ribosomal protein L34 | -0.0214533 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0214236 |
| RND3 | Rho family GTPase 3 | -0.0213173 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0210395 |
| AHNAK | AHNAK nucleoprotein | -0.0209244 |
| CCND1 | cyclin D1 | -0.0207042 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0206018 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0205711 |
| CLMP | CXADR-like membrane protein | -0.0204464 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0203033 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0203007 |
| RPS24 | ribosomal protein S24 | -0.020085 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.019782 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0195184 |
| GPC5 | glypican 5 | -0.0191819 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0190507 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0189149 |
| ANXA4 | annexin A4 | -0.0188719 |
| BNC2 | basonuclin 2 | -0.0188385 |
| OXR1 | oxidation resistance 1 | -0.0187549 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0185854 |
| CANX | calnexin | -0.0184428 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0183683 |
| S100A11 | S100 calcium binding protein A11 | -0.0183625 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.018324 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0182263 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0181104 |
| OSMR | oncostatin M receptor | -0.0180899 |
| GNAS | GNAS complex locus | -0.0180397 |
| FRMD5 | FERM domain containing 5 | -0.0179415 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0178982 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0177236 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0176918 |
| HM13 | histocompatibility (minor) 13 | -0.017547 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0173194 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0173149 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0172811 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0171903 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0170564 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0165083 |
