| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ferulic acid perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ferulic acid_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.132035 |
| NDRG1 | N-myc downstream regulated 1 | 0.128974 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.127565 |
| FLNB | filamin B, beta | 0.110797 |
| SMAD3 | SMAD family member 3 | 0.109141 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0997877 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.097844 |
| PLEC | plectin | 0.0973194 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0968542 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0877873 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.082334 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0773717 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0754318 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0739423 |
| MSN | moesin | 0.0735405 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0637383 |
| FLNA | filamin A, alpha | 0.061035 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0575062 |
| PKM | pyruvate kinase, muscle | 0.0570523 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0556394 |
| NAV2 | neuron navigator 2 | 0.0537985 |
| MCL1 | myeloid cell leukemia 1 | 0.0518097 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0510689 |
| RPL3 | ribosomal protein L3 | 0.0499193 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0498884 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0496949 |
| EGR1 | early growth response 1 | 0.0495265 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0493971 |
| SEPTIN9 | septin 9 | 0.0486524 |
| FMNL2 | formin-like 2 | 0.0474783 |
| TNS1 | tensin 1 | 0.046599 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0452041 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0451751 |
| AUTS2 | autism susceptibility candidate 2 | 0.0447561 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0443966 |
| NUP58 | nucleoporin 58 | 0.0435665 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0428724 |
| POTEF | POTE ankyrin domain family, member F | 0.0425634 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0423935 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0412059 |
| VEGFA | vascular endothelial growth factor A | 0.0409959 |
| PTK2 | protein tyrosine kinase 2 | 0.0406328 |
| HELZ | helicase with zinc finger | 0.0402188 |
| SPAG9 | sperm associated antigen 9 | 0.0400309 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0396446 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0378774 |
| C1D | C1D nuclear receptor corepressor | 0.0372654 |
| COPA | coatomer protein complex, subunit alpha | 0.0369338 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0368582 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0363978 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0357836 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0349058 |
| NONO | non-POU domain containing, octamer-binding | 0.0347082 |
| CTBP2 | C-terminal binding protein 2 | 0.0345683 |
| KRT18 | keratin 18, type I | 0.0343276 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0336901 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0334154 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0333653 |
| MKI67 | marker of proliferation Ki-67 | 0.0333216 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0327278 |
| RPS3 | ribosomal protein S3 | 0.0325201 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0324398 |
| AXL | AXL receptor tyrosine kinase | 0.032331 |
| BCL2L1 | BCL2-like 1 | 0.0320645 |
| MINK1 | misshapen-like kinase 1 | 0.0316617 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0316346 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0315916 |
| STC1 | stanniocalcin 1 | 0.0314479 |
| PFN1 | profilin 1 | 0.0309011 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0304077 |
| TPM3 | tropomyosin 3 | 0.0301847 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0301314 |
| ACTN1 | actinin, alpha 1 | 0.0300999 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0300472 |
| MED15 | mediator complex subunit 15 | 0.0298902 |
| CD44 | CD44 molecule (Indian blood group) | 0.0295883 |
| LTBP4 | latent transforming growth factor beta binding protein 4 | 0.0293665 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.029337 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0288962 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0287963 |
| FAM13A | family with sequence similarity 13, member A | 0.0285896 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0285253 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0285157 |
| FOSL1 | FOS-like antigen 1 | 0.0279906 |
| MT2A | metallothionein 2A | 0.0279588 |
| PARD3 | par-3 family cell polarity regulator | 0.0279414 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0277975 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0277586 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0277253 |
| MYO10 | myosin X | 0.0272776 |
| PCBP2 | poly(rC) binding protein 2 | 0.0271964 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.027111 |
| HDGF | hepatoma-derived growth factor | 0.0269646 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0269463 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0268917 |
| USP3 | ubiquitin specific peptidase 3 | 0.0267203 |
| KCTD9 | potassium channel tetramerization domain containing 9 | 0.0266311 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0265708 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0264193 |
| DUSP5 | dual specificity phosphatase 5 | 0.0260519 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.100583 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0811495 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0789362 |
| KYNU | kynureninase | -0.077144 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0691656 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0680435 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0678226 |
| OSMR | oncostatin M receptor | -0.0635683 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.062327 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0618475 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0582545 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0554112 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0534885 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0517688 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0503224 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.048075 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.046604 |
| RPL4 | ribosomal protein L4 | -0.0463135 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0455379 |
| TXNRD1 | thioredoxin reductase 1 | -0.0449818 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0436006 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0433708 |
| EHBP1 | EH domain binding protein 1 | -0.0433271 |
| TMSB10 | thymosin beta 10 | -0.0432739 |
| AHNAK | AHNAK nucleoprotein | -0.0426035 |
| RPS24 | ribosomal protein S24 | -0.0419437 |
| RPLP1 | ribosomal protein, large, P1 | -0.0417252 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0329595 |
| RRBP1 | ribosome binding protein 1 | -0.0328627 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0318686 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0309749 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0308998 |
| GLIS3 | GLIS family zinc finger 3 | -0.0307494 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0305023 |
| PDE10A | phosphodiesterase 10A | -0.0296442 |
| EFNA5 | ephrin-A5 | -0.0295313 |
| RPS16 | ribosomal protein S16 | -0.0292085 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.02879 |
| RAI14 | retinoic acid induced 14 | -0.0282374 |
| RIGI | RNA sensor RIG-I | -0.0282027 |
| CA12 | carbonic anhydrase XII | -0.028163 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0278311 |
| S100A6 | S100 calcium binding protein A6 | -0.0274368 |
| BICC1 | BicC family RNA binding protein 1 | -0.0273895 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0269843 |
| CEP95 | centrosomal protein 95kDa | -0.0268838 |
| RPL12 | ribosomal protein L12 | -0.0265386 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0262485 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0261435 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0254322 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0244932 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0241697 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0240235 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0237095 |
| CLDN1 | claudin 1 | -0.0233114 |
| NRP1 | neuropilin 1 | -0.0231147 |
| MYO9A | myosin IXA | -0.0227027 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0226985 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0225825 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0221921 |
| LDHA | lactate dehydrogenase A | -0.0221709 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0220492 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0219861 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0211821 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0211607 |
| BMERB1 | bMERB domain containing 1 | -0.0208965 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0206357 |
| PMP22 | peripheral myelin protein 22 | -0.0205904 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0202332 |
| UBB | ubiquitin B | -0.0201649 |
| GPRIN3 | GPRIN family member 3 | -0.0201168 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0200535 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0198436 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0196394 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0194342 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0194156 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0190451 |
| PLSCR1 | phospholipid scramblase 1 | -0.0188555 |
| NF1 | neurofibromin 1 | -0.0188535 |
| GABRB3 | gamma-aminobutyric acid (GABA) A receptor, beta 3 | -0.0188322 |
| SBF2 | SET binding factor 2 | -0.0187318 |
| RPL26 | ribosomal protein L26 | -0.0186969 |
| RIC8B | RIC8 guanine nucleotide exchange factor B | -0.0186321 |
| HLA-E | major histocompatibility complex, class I, E | -0.0185828 |
| GNAS | GNAS complex locus | -0.0183274 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0182622 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0180954 |
| EXOC6B | exocyst complex component 6B | -0.0180605 |
| ABLIM1 | actin binding LIM protein 1 | -0.0180032 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0180008 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0179647 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0171033 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0170125 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.016903 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0168718 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.0167323 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0166536 |
| ETV6 | ets variant 6 | -0.0166417 |
| RSPO3 | R-spondin 3 | -0.0166333 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0164726 |