Ferulic acid_AsPC-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in AsPC-1 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Ferulic acid_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FLNB filamin B, beta 0.288052
AKAP12 A kinase (PRKA) anchor protein 12 0.210361
LAMB3 laminin, beta 3 0.190775
PTMA prothymosin, alpha 0.180991
PLEC plectin 0.144943
MYH9 myosin, heavy chain 9, non-muscle 0.109411
BAIAP2L1 BAI1-associated protein 2-like 1 0.10481
LMTK2 lemur tyrosine kinase 2 0.0968166
KRT18 keratin 18, type I 0.0944908
EEF2 eukaryotic translation elongation factor 2 0.0888818
ITPRID2 ITPR interacting domain containing 2 0.0859905
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0847225
KRT8 keratin 8, type II 0.0820929
EZR ezrin 0.075331
ACTG1 actin gamma 1 0.0727838
RPS3 ribosomal protein S3 0.069088
MPRIP myosin phosphatase Rho interacting protein 0.0677904
LMO7 LIM domain 7 0.0674737
UPP1 uridine phosphorylase 1 0.0662991
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.066113
DSPP dentin sialophosphoprotein 0.0649019
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.0639816
GRB10 growth factor receptor-bound protein 10 0.0634094
BHLHE40 basic helix-loop-helix family, member e40 0.0629695
SLMAP sarcolemma associated protein 0.062072
RPL37A ribosomal protein L37a 0.0605772
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0603368
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0576138
RACK1 receptor for activated C kinase 1 0.0558052
TNIP1 TNFAIP3 interacting protein 1 0.0555566
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.0544413
RPS12 ribosomal protein S12 0.0539361
B2M beta-2-microglobulin 0.0536245
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0518873
TPM3 tropomyosin 3 0.0514033
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0509778
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.050316
BIRC6 baculoviral IAP repeat containing 6 0.0492208
MXD1 MAX dimerization protein 1 0.0492189
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0482611
EGR1 early growth response 1 0.0477363
SRRM2 serine/arginine repetitive matrix 2 0.0468346
LOC112694756 uncharaterized LOC112694756 0.0467877
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.046724
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.04626
RCOR1 REST corepressor 1 0.044933
MUC17 mucin 17, cell surface associated 0.0449279
ANXA2 annexin A2 0.0439917
NCOA3 nuclear receptor coactivator 3 0.0437417
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0436028
FOSL1 FOS-like antigen 1 0.0434825
PGK1 phosphoglycerate kinase 1 0.0431433
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0428823
PTPRF protein tyrosine phosphatase, receptor type, F 0.0425374
F3 coagulation factor III (thromboplastin, tissue factor) 0.0424512
ESYT2 extended synaptotagmin-like protein 2 0.0422334
KCMF1 potassium channel modulatory factor 1 0.0421329
LAMC2 laminin, gamma 2 0.0420908
UBA6 ubiquitin-like modifier activating enzyme 6 0.0419438
NCOR2 nuclear receptor corepressor 2 0.0418336
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0409392
STK39 serine threonine kinase 39 0.0405685
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0404244
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.040216
S100A10 S100 calcium binding protein A10 0.0391389
FAM107B family with sequence similarity 107, member B 0.0386905
OSBP2 oxysterol binding protein 2 0.038657
KIRREL1 kirre like nephrin family adhesion molecule 1 0.0381459
EIF3H eukaryotic translation initiation factor 3, subunit H 0.0375127
FSCN1 fascin actin-bundling protein 1 0.0372154
RPS27A ribosomal protein S27a 0.0369294
RPL26 ribosomal protein L26 0.0366196
RPS8 ribosomal protein S8 0.0365028
PLAUR plasminogen activator, urokinase receptor 0.0363419
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.0360022
RBM39 RNA binding motif protein 39 0.0357357
FTH1 ferritin, heavy polypeptide 1 0.0351195
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.035022
NONO non-POU domain containing, octamer-binding 0.0341499
CTBP2 C-terminal binding protein 2 0.0339308
SFTPA2 surfactant protein A2 0.0338175
FA2H fatty acid 2-hydroxylase 0.0330766
MED15 mediator complex subunit 15 0.0329169
PPDPF pancreatic progenitor cell differentiation and proliferation factor 0.032806
RPL30 ribosomal protein L30 0.032769
EPCAM epithelial cell adhesion molecule 0.0325198
FOXO3 forkhead box O3 0.0323292
HRNR hornerin 0.0321261
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.0320153
EPS8 epidermal growth factor receptor pathway substrate 8 0.0312482
PTK2 protein tyrosine kinase 2 0.0311198
EIF3E eukaryotic translation initiation factor 3, subunit E 0.0309178
JUP junction plakoglobin 0.0309035
HSPA8 heat shock 70kDa protein 8 0.0308701
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0306883
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0302913
APP amyloid beta (A4) precursor protein 0.0301795
RPS10 ribosomal protein S10 0.0301075
TMSB4X thymosin beta 4, X-linked 0.0299036
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.0296294

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0704372
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.056033
EFNA5 ephrin-A5 -0.0550892
EGFR epidermal growth factor receptor -0.0455193
MBNL1 muscleblind-like splicing regulator 1 -0.0371404
ZBTB20 zinc finger and BTB domain containing 20 -0.0365554
MT2A metallothionein 2A -0.0353128
OSMR oncostatin M receptor -0.0351871
TXNRD1 thioredoxin reductase 1 -0.0338239
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa -0.0331535
DOCK5 dedicator of cytokinesis 5 -0.0320037
VIM vimentin -0.0311655
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.029797
JMJD1C jumonji domain containing 1C -0.0291619
VCL vinculin -0.0283037
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0269263
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0263378
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -0.024529
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.0242241
PDE4D phosphodiesterase 4D, cAMP-specific -0.0238297
HMGA2 high mobility group AT-hook 2 -0.0236412
RIGI RNA sensor RIG-I -0.023283
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0230715
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.023047
ADNP activity-dependent neuroprotector homeobox -0.0222268
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -0.0220328
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0219968
EHBP1 EH domain binding protein 1 -0.0219174
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.0211802
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy -0.0208399
TSC22D2 TSC22 domain family, member 2 -0.0206178
IFI16 interferon, gamma-inducible protein 16 -0.0203773
GREB1L growth regulation by estrogen in breast cancer-like -0.0202628
MAML2 mastermind-like 2 (Drosophila) -0.0200465
UBC ubiquitin C -0.0199923
TXNIP thioredoxin interacting protein -0.0199208
RPS24 ribosomal protein S24 -0.0197706
EXT1 exostosin glycosyltransferase 1 -0.0197558
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats -0.019743
AHNAK AHNAK nucleoprotein -0.0194119
ATP5F1B ATP synthase F1 subunit beta -0.0193975
FER fer (fps/fes related) tyrosine kinase -0.0193559
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like -0.019095
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.0188604
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.018829
SDC4 syndecan 4 -0.0183363
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0178801
NF1 neurofibromin 1 -0.0176544
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0175572
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -0.0174543
HP1BP3 heterochromatin protein 1, binding protein 3 -0.0173708
ANTXR2 anthrax toxin receptor 2 -0.0173614
RBM25 RNA binding motif protein 25 -0.0171844
ARB2A ARB2 cotranscriptional regulator A -0.0169099
SLC38A2 solute carrier family 38, member 2 -0.0165696
BPTF bromodomain PHD finger transcription factor -0.0165541
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.0163569
AGO2 argonaute RISC catalytic component 2 -0.0162557
MED13 mediator complex subunit 13 -0.016168
RTN4 reticulon 4 -0.0161458
PMP22 peripheral myelin protein 22 -0.0161258
PCBP2 poly(rC) binding protein 2 -0.0159653
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -0.0158802
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0158197
AKAP9 A kinase (PRKA) anchor protein 9 -0.0157158
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0156164
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.0155565
HDAC9 histone deacetylase 9 -0.0155415
MBD5 methyl-CpG binding domain protein 5 -0.015423
NABP1 nucleic acid binding protein 1 -0.0154083
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0152794
EPSTI1 epithelial stromal interaction 1 (breast) -0.0152525
LOC102724023 ES1 protein homolog, mitochondrial -0.0152153
FRYL FRY-like -0.0151738
PKP4 plakophilin 4 -0.0151512
AVL9 AVL9 homolog (S. cerevisiase) -0.01491
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 -0.0148918
LNPEP leucyl/cystinyl aminopeptidase -0.0147917
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0147822
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -0.0147318
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0146995
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.0145436
CDCP1 CUB domain containing protein 1 -0.0145369
LPP LIM domain containing preferred translocation partner in lipoma -0.0143327
C6ORF62 chromosome 6 open reading frame 62 -0.0142931
CENPF centromere protein F, 350/400kDa -0.0142723
SAMD9 sterile alpha motif domain containing 9 -0.0142658
TGM2 transglutaminase 2 -0.0142478
LCOR ligand dependent nuclear receptor corepressor -0.0142245
SERINC5 serine incorporator 5 -0.0142243
FAM3C family with sequence similarity 3, member C -0.0141487
RPL28 ribosomal protein L28 -0.0141436
ANKIB1 ankyrin repeat and IBR domain containing 1 -0.0141077
UBE2R2 ubiquitin-conjugating enzyme E2R 2 -0.0140708
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0140489
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0140487
CYB5R3 cytochrome b5 reductase 3 -0.0139875
TUT7 terminal uridylyl transferase 7 -0.0139854
RABGAP1L RAB GTPase activating protein 1-like -0.0139793
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0139574