Ferulic acid_C-33 A Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in C-33 A cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Ferulic acid_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.134654
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.12467
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.123297
KMT2C lysine (K)-specific methyltransferase 2C 0.0956657
ZNF292 zinc finger protein 292 0.0855977
CABIN1 calcineurin binding protein 1 0.0819387
SMYD3 SET and MYND domain containing 3 0.0805487
NUP58 nucleoporin 58 0.0787783
EEF2 eukaryotic translation elongation factor 2 0.0762066
PIAS2 protein inhibitor of activated STAT, 2 0.0722138
HELZ helicase with zinc finger 0.0674905
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0599877
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0585257
ATRN attractin 0.0580736
KDM3A lysine (K)-specific demethylase 3A 0.0578777
EGLN1 egl-9 family hypoxia-inducible factor 1 0.0572302
FMNL2 formin-like 2 0.0569913
RPL3 ribosomal protein L3 0.0552523
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.054315
PTK2 protein tyrosine kinase 2 0.0532115
USP9X ubiquitin specific peptidase 9, X-linked 0.0527667
SREBF2 sterol regulatory element binding transcription factor 2 0.0519492
DST dystonin 0.0515673
NGLY1 N-glycanase 1 0.0514067
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0507307
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0500596
KDM6A lysine (K)-specific demethylase 6A 0.0499468
NFIA nuclear factor I/A 0.0490057
PDK3 pyruvate dehydrogenase kinase, isozyme 3 0.0489996
CAMTA1 calmodulin binding transcription activator 1 0.0483212
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.047763
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.0470206
QKI QKI, KH domain containing, RNA binding 0.0459653
YEATS2 YEATS domain containing 2 0.0458843
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.0449852
CHD7 chromodomain helicase DNA binding protein 7 0.0448935
ARFGEF3 ARFGEF family member 3 0.0446227
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0440332
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 0.0437037
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.0435582
MED13L mediator complex subunit 13-like 0.0432503
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.0432157
OGA O-GlcNAcase 0.0432124
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0420386
FAM168A family with sequence similarity 168, member A 0.0408814
PTCH1 patched 1 0.0401102
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0399213
KMT2E lysine (K)-specific methyltransferase 2E 0.0396328
SRSF4 serine/arginine-rich splicing factor 4 0.0395842
ATP11A ATPase, class VI, type 11A 0.0392176
PARD3 par-3 family cell polarity regulator 0.0390417
FOXO3 forkhead box O3 0.0389438
WSB1 WD repeat and SOCS box containing 1 0.038035
TTC28 tetratricopeptide repeat domain 28 0.0378486
PGK1 phosphoglycerate kinase 1 0.0376138
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.0375129
AUTS2 autism susceptibility candidate 2 0.0374966
ADAR adenosine deaminase, RNA-specific 0.0374743
KDM1A lysine (K)-specific demethylase 1A 0.037216
GYS1 glycogen synthase 1 (muscle) 0.0365763
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0365271
KIAA1958 KIAA1958 0.036473
SSBP2 single-stranded DNA binding protein 2 0.0363358
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0362886
DIDO1 death inducer-obliterator 1 0.0360994
EIF4B eukaryotic translation initiation factor 4B 0.0360424
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.03604
JARID2 jumonji, AT rich interactive domain 2 0.0357216
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0356299
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0355808
ZNF638 zinc finger protein 638 0.0353624
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0351075
CCNY cyclin Y 0.0347124
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 0.0346021
PHIP pleckstrin homology domain interacting protein 0.0345271
BIRC6 baculoviral IAP repeat containing 6 0.0344625
UBA6 ubiquitin-like modifier activating enzyme 6 0.0344195
TOP2B topoisomerase (DNA) II beta 180kDa 0.0343085
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0340077
SRRM2 serine/arginine repetitive matrix 2 0.0338017
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0337367
CHSY1 chondroitin sulfate synthase 1 0.0331866
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0330811
MACF1 microtubule-actin crosslinking factor 1 0.033068
MSI2 musashi RNA-binding protein 2 0.0329434
NCOR1 nuclear receptor corepressor 1 0.0328561
ZNF608 zinc finger protein 608 0.0328151
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.0324806
INSIG2 insulin induced gene 2 0.0324469
TRIO trio Rho guanine nucleotide exchange factor 0.0323684
XPO1 exportin 1 0.0323615
BBX bobby sox homolog (Drosophila) 0.0322709
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.0322276
FAT1 FAT atypical cadherin 1 0.0321693
SUN1 Sad1 and UNC84 domain containing 1 0.0321006
CASC3 cancer susceptibility candidate 3 0.0319031
CDC73 cell division cycle 73 0.0317186
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0317082
PCNX1 pecanex 1 0.0312955
MXI1 MAX interactor 1, dimerization protein 0.0311116

decreased expression

Symbol Name Standardized Value
ERBB4 erb-b2 receptor tyrosine kinase 4 -0.138935
SLIT2 slit homolog 2 (Drosophila) -0.100547
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0681432
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D -0.0615263
PTMA prothymosin, alpha -0.0514893
IFI6 interferon, alpha-inducible protein 6 -0.0506089
MCTP1 multiple C2 domains, transmembrane 1 -0.0472078
RIGI RNA sensor RIG-I -0.042187
SOX4 SRY (sex determining region Y)-box 4 -0.0416177
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0416001
ACTG1 actin gamma 1 -0.0415756
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0413867
RPLP1 ribosomal protein, large, P1 -0.0411971
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0394659
RPS6 ribosomal protein S6 -0.0387731
TMSB10 thymosin beta 10 -0.0368919
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0358395
PDE4D phosphodiesterase 4D, cAMP-specific -0.0345243
RPS8 ribosomal protein S8 -0.0320557
RPS24 ribosomal protein S24 -0.0315664
RPL34 ribosomal protein L34 -0.0307324
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0304777
PRICKLE1 prickle homolog 1 (Drosophila) -0.028491
RPLP2 ribosomal protein, large, P2 -0.0282753
CTNNA3 catenin (cadherin-associated protein), alpha 3 -0.0282262
HMGB1 high mobility group box 1 -0.0282007
RPL12 ribosomal protein L12 -0.0271525
MLIP muscular LMNA-interacting protein -0.0270274
RPL31 ribosomal protein L31 -0.0266968
RPL35A ribosomal protein L35a -0.0264752
CADM2 cell adhesion molecule 2 -0.0260525
RPL19 ribosomal protein L19 -0.0252498
RBBP6 retinoblastoma binding protein 6 -0.0246478
RPS5 ribosomal protein S5 -0.0242784
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -0.0240878
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -0.023806
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0232006
RPS19 ribosomal protein S19 -0.0226505
TPT1 tumor protein, translationally-controlled 1 -0.0223618
BNC2 basonuclin 2 -0.0213475
VCL vinculin -0.0213014
EIF5B eukaryotic translation initiation factor 5B -0.0211813
MYL12B myosin, light chain 12B, regulatory -0.0205571
RPL5 ribosomal protein L5 -0.0205378
ZBTB20 zinc finger and BTB domain containing 20 -0.0198855
OSBPL10 oxysterol binding protein-like 10 -0.019613
EIF1 eukaryotic translation initiation factor 1 -0.0195823
VIM vimentin -0.019276
PFN1 profilin 1 -0.0191999
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.0191487
RPS21 ribosomal protein S21 -0.0191194
VMP1 vacuole membrane protein 1 -0.0191021
AKAP6 A kinase (PRKA) anchor protein 6 -0.0189632
RPL9 ribosomal protein L9 -0.0186769
HHIP hedgehog interacting protein -0.0183536
RPL28 ribosomal protein L28 -0.0182652
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0181425
RPS29 ribosomal protein S29 -0.01768
PCNX4 pecanex 4 -0.0176725
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0174037
RPS28 ribosomal protein S28 -0.0171986
PMP22 peripheral myelin protein 22 -0.0170699
HMGA1 high mobility group AT-hook 1 -0.0170384
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0167054
IARS1 isoleucyl-tRNA synthetase 1 -0.0166435
RPS20 ribosomal protein S20 -0.0164482
PRH1 proline-rich protein HaeIII subfamily 1 -0.0163314
NRG1 neuregulin 1 -0.0163033
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -0.0162212
RPL26 ribosomal protein L26 -0.0160622
LARS1 leucyl-tRNA synthetase 1 -0.0160227
PHF14 PHD finger protein 14 -0.0159103
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0158678
BICD1 bicaudal D homolog 1 (Drosophila) -0.0154886
RPS27A ribosomal protein S27a -0.0154623
CCDC138 coiled-coil domain containing 138 -0.0154282
RPL32 ribosomal protein L32 -0.0154047
RPL18 ribosomal protein L18 -0.0152674
FTL ferritin, light polypeptide -0.0151978
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0151843
RPS23 ribosomal protein S23 -0.0150103
VDAC1 voltage-dependent anion channel 1 -0.0145788
SIK2 salt-inducible kinase 2 -0.0143745
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0142571
BRCA1 breast cancer 1, early onset -0.0142535
ISG15 ISG15 ubiquitin-like modifier -0.0142468
FBXL7 F-box and leucine-rich repeat protein 7 -0.0142288
NARS1 asparaginyl-tRNA synthetase 1 -0.0140968
RPS2 ribosomal protein S2 -0.0139669
SOX2 SRY (sex determining region Y)-box 2 -0.013872
ZRANB2 zinc finger, RAN-binding domain containing 2 -0.0138069
ZNFX1 zinc finger, NFX1-type containing 1 -0.01374
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -0.0137377
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0136375
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0136275
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -0.0135737
THADA thyroid adenoma associated -0.0135696
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0134835
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.0132134
DNAH14 dynein, axonemal, heavy chain 14 -0.0131948