Ferulic acid_C32 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in C32 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Ferulic acid_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
NDRG1 N-myc downstream regulated 1 0.109527
FN1 fibronectin 1 0.105893
NAMPT nicotinamide phosphoribosyltransferase 0.0805844
VGF VGF nerve growth factor inducible 0.0660363
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0647219
LEF1 lymphoid enhancer-binding factor 1 0.0640248
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0614138
CD109 CD109 molecule 0.06117
BHLHE40 basic helix-loop-helix family, member e40 0.0548062
ICAM1 intercellular adhesion molecule 1 0.0537845
EEF2 eukaryotic translation elongation factor 2 0.0464974
TMEM178B transmembrane protein 178B 0.0452925
KMT2C lysine (K)-specific methyltransferase 2C 0.0451006
CPEB2 cytoplasmic polyadenylation element binding protein 2 0.0433051
RNASE12 ribonuclease, RNase A family, 12 (non-active) 0.0426889
FNDC3B fibronectin type III domain containing 3B 0.0423946
CABIN1 calcineurin binding protein 1 0.0419032
NBAS neuroblastoma amplified sequence 0.0415432
FYN FYN proto-oncogene, Src family tyrosine kinase 0.040843
APP amyloid beta (A4) precursor protein 0.0405677
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0403835
PRELID2 PRELI domain containing 2 0.0401867
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 0.0399501
MIDEAS mitotic deacetylase associated SANT domain protein 0.0397495
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0397418
NAV2 neuron navigator 2 0.0396535
MYH9 myosin, heavy chain 9, non-muscle 0.0394893
CDC73 cell division cycle 73 0.0392375
NUP58 nucleoporin 58 0.0390234
COPA coatomer protein complex, subunit alpha 0.0389634
EGLN1 egl-9 family hypoxia-inducible factor 1 0.0386116
ESYT2 extended synaptotagmin-like protein 2 0.0376645
VEGFA vascular endothelial growth factor A 0.0368304
LOC112694756 uncharaterized LOC112694756 0.0367838
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.035485
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0352122
KIRREL1 kirre like nephrin family adhesion molecule 1 0.0350754
CHSY1 chondroitin sulfate synthase 1 0.0348064
LUC7L2 LUC7-like 2 (S. cerevisiae) 0.0341005
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0328858
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.032004
KMT2E lysine (K)-specific methyltransferase 2E 0.0312444
PLEC plectin 0.0305103
FOSL1 FOS-like antigen 1 0.0303638
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0303292
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0302396
RBM33 RNA binding motif protein 33 0.0302235
ARRDC3 arrestin domain containing 3 0.0301795
UBE2H ubiquitin-conjugating enzyme E2H 0.030049
EPS8 epidermal growth factor receptor pathway substrate 8 0.0299721
SMAD3 SMAD family member 3 0.0298776
HELZ helicase with zinc finger 0.0298071
ACSL3 acyl-CoA synthetase long-chain family member 3 0.0294503
FBXO7 F-box protein 7 0.0290301
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.028822
RPL3 ribosomal protein L3 0.0287797
FLNA filamin A, alpha 0.0286663
MED15 mediator complex subunit 15 0.0286425
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.0280676
MRTFA myocardin related transcription factor A 0.0277222
SSBP3 single stranded DNA binding protein 3 0.0271284
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0268643
DSCAM Down syndrome cell adhesion molecule 0.0266105
MACF1 microtubule-actin crosslinking factor 1 0.0263504
ZYX zyxin 0.0262898
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.0259034
IL1RAP interleukin 1 receptor accessory protein 0.0257124
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0256006
SETBP1 SET binding protein 1 0.0255783
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.0252973
ACTN1 actinin, alpha 1 0.0248631
SND1 staphylococcal nuclease and tudor domain containing 1 0.0248018
SEPTIN9 septin 9 0.0247106
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0244221
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0241288
RIPK4 receptor-interacting serine-threonine kinase 4 0.0240963
ANO6 anoctamin 6 0.0240102
VMP1 vacuole membrane protein 1 0.023212
GAS7 growth arrest-specific 7 0.0231164
SRPK2 SRSF protein kinase 2 0.0230563
TNNC1 troponin C type 1 (slow) 0.0227242
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.0224796
SRRM2 serine/arginine repetitive matrix 2 0.0223923
ZMIZ1 zinc finger, MIZ-type containing 1 0.0223885
HOOK2 hook microtubule-tethering protein 2 0.0219368
ATXN1 ataxin 1 0.0216604
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0216101
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.0215959
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0214557
MSN moesin 0.0213248
SOX10 SRY (sex determining region Y)-box 10 0.0213144
SAMD4A sterile alpha motif domain containing 4A 0.0212688
PHF21A PHD finger protein 21A 0.0211769
PKM pyruvate kinase, muscle 0.0211228
FMNL2 formin-like 2 0.0208347
TAC4 tachykinin 4 (hemokinin) 0.0207821
PHC2 polyhomeotic homolog 2 (Drosophila) 0.0206165
NEK7 NIMA-related kinase 7 0.0204913
TENT4A terminal nucleotidyltransferase 4A 0.0204748
NUMA1 nuclear mitotic apparatus protein 1 0.0204688

decreased expression

Symbol Name Standardized Value
VIM vimentin -0.183865
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.149045
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.147027
IGFBP5 insulin-like growth factor binding protein 5 -0.124358
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.112727
NLGN1 neuroligin 1 -0.0809567
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -0.0797822
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0787674
S100A6 S100 calcium binding protein A6 -0.0671105
IFI16 interferon, gamma-inducible protein 16 -0.0626371
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0619603
AKAP12 A kinase (PRKA) anchor protein 12 -0.056156
PDIA4 protein disulfide isomerase family A, member 4 -0.0536039
PTMA prothymosin, alpha -0.0535666
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0510089
TMSB10 thymosin beta 10 -0.0468143
HLA-B major histocompatibility complex, class I, B -0.0460445
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0443408
IER3 immediate early response 3 -0.041692
ACTG1 actin gamma 1 -0.041437
GDF15 growth differentiation factor 15 -0.0397107
TPT1 tumor protein, translationally-controlled 1 -0.0395617
CENPF centromere protein F, 350/400kDa -0.0370416
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 -0.036404
EHBP1 EH domain binding protein 1 -0.0358335
GPC6 glypican 6 -0.0346272
PTCHD4 patched domain containing 4 -0.0336445
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0327585
VDAC1 voltage-dependent anion channel 1 -0.0315937
PTPRD protein tyrosine phosphatase, receptor type, D -0.0312769
HILPDA hypoxia inducible lipid droplet-associated -0.0310461
CANX calnexin -0.0301764
RPLP1 ribosomal protein, large, P1 -0.0299888
ENO1 enolase 1, (alpha) -0.0299355
FTL ferritin, light polypeptide -0.0296954
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0289451
TIMP3 TIMP metallopeptidase inhibitor 3 -0.0283412
AHNAK AHNAK nucleoprotein -0.0271827
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -0.026796
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0267061
PDIA3 protein disulfide isomerase family A, member 3 -0.0262954
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.0259874
SCFD2 sec1 family domain containing 2 -0.0258882
NPR2 natriuretic peptide receptor 2 -0.0248049
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -0.0244578
CTSD cathepsin D -0.0244126
IFITM3 interferon induced transmembrane protein 3 -0.0242362
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0235277
TMEM123 transmembrane protein 123 -0.0234173
PLIN2 perilipin 2 -0.0231537
MTDH metadherin -0.0225995
HLA-A major histocompatibility complex, class I, A -0.0224508
HMGA2 high mobility group AT-hook 2 -0.0222179
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa -0.0221007
GNAS GNAS complex locus -0.021874
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.021504
RPL34 ribosomal protein L34 -0.0213061
RPS8 ribosomal protein S8 -0.0210131
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0204023
RRBP1 ribosome binding protein 1 -0.0201456
TAS2R14 taste receptor, type 2, member 14 -0.0200599
NAV3 neuron navigator 3 -0.020009
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0197893
MACROD2 MACRO domain containing 2 -0.0197114
IFI6 interferon, alpha-inducible protein 6 -0.0195351
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0193135
RPL35A ribosomal protein L35a -0.0189601
IFITM1 interferon induced transmembrane protein 1 -0.0186172
IRF2BP2 interferon regulatory factor 2 binding protein 2 -0.0186093
MMP16 matrix metallopeptidase 16 (membrane-inserted) -0.0185476
S100A9 S100 calcium binding protein A9 -0.0185098
CALU calumenin -0.0184183
HMGB1 high mobility group box 1 -0.0181917
CALD1 caldesmon 1 -0.0177096
CCND1 cyclin D1 -0.017634
RPS6 ribosomal protein S6 -0.0175922
S100A10 S100 calcium binding protein A10 -0.0175885
DCT dopachrome tautomerase -0.017479
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0173967
COL19A1 collagen, type XIX, alpha 1 -0.0172938
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0171104
RPS24 ribosomal protein S24 -0.0171025
FAM162A family with sequence similarity 162, member A -0.0170049
NAP1L1 nucleosome assembly protein 1-like 1 -0.0167925
BTG1 B-cell translocation gene 1, anti-proliferative -0.016352
FBXO11 F-box protein 11 -0.0161196
RPLP2 ribosomal protein, large, P2 -0.0159966
ZNF704 zinc finger protein 704 -0.0159212
CALR calreticulin -0.0157874
SLC38A1 solute carrier family 38, member 1 -0.0156367
RNF24 ring finger protein 24 -0.0155238
CUX1 cut-like homeobox 1 -0.0154842
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0154152
TET1 tet methylcytosine dioxygenase 1 -0.0153444
ZBTB20 zinc finger and BTB domain containing 20 -0.0153356
BZW1 basic leucine zipper and W2 domains 1 -0.0152914
GLG1 golgi glycoprotein 1 -0.0149324
EIF5B eukaryotic translation initiation factor 5B -0.0147227
TPM4 tropomyosin 4 -0.014655
GOLGB1 golgin B1 -0.0146331