Ferulic acid_CFPAC-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in CFPAC-1 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Ferulic acid_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
MYH9 myosin, heavy chain 9, non-muscle 0.163249
PTMA prothymosin, alpha 0.158079
TMSB10 thymosin beta 10 0.154449
LAMB3 laminin, beta 3 0.126801
PLAU plasminogen activator, urokinase 0.125476
VEGFA vascular endothelial growth factor A 0.119175
ANKRD11 ankyrin repeat domain 11 0.111143
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.111065
WSB1 WD repeat and SOCS box containing 1 0.108731
NDRG1 N-myc downstream regulated 1 0.100982
ANXA2 annexin A2 0.0989048
FLNB filamin B, beta 0.0988996
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0868968
GRB10 growth factor receptor-bound protein 10 0.0861358
CCNY cyclin Y 0.0839063
FAM13A family with sequence similarity 13, member A 0.0838945
IGFBP3 insulin-like growth factor binding protein 3 0.0828001
PLEC plectin 0.0818649
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0795963
TSC22D2 TSC22 domain family, member 2 0.074415
LOC112694756 uncharaterized LOC112694756 0.0726295
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0724478
TNIP1 TNFAIP3 interacting protein 1 0.0715186
TMSB4X thymosin beta 4, X-linked 0.0714671
DDIT4 DNA-damage-inducible transcript 4 0.0714325
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0709474
KRT8 keratin 8, type II 0.0709409
G0S2 G0/G1 switch 2 0.0696261
EEF2 eukaryotic translation elongation factor 2 0.0689384
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.0686297
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.067639
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0673277
NAMPT nicotinamide phosphoribosyltransferase 0.0668697
APP amyloid beta (A4) precursor protein 0.0643984
HPCAL1 hippocalcin-like 1 0.0634845
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0620839
RPL23 ribosomal protein L23 0.0619228
PGK1 phosphoglycerate kinase 1 0.0614889
ACTG1 actin gamma 1 0.060601
ELL2 elongation factor, RNA polymerase II, 2 0.0601093
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0597212
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0596448
MT1X metallothionein 1X 0.0574712
CALR calreticulin 0.0573716
BHLHE40 basic helix-loop-helix family, member e40 0.0566192
YBX1 Y box binding protein 1 0.0562685
FLNA filamin A, alpha 0.0555811
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0554937
H1-0 H1.0 linker histone 0.0549191
KRT18 keratin 18, type I 0.0544419
FOSL1 FOS-like antigen 1 0.0536071
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0524354
USP3 ubiquitin specific peptidase 3 0.0518111
FTH1 ferritin, heavy polypeptide 1 0.0496435
RBM39 RNA binding motif protein 39 0.0496071
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0487077
F3 coagulation factor III (thromboplastin, tissue factor) 0.0486698
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0476586
MT2A metallothionein 2A 0.0472453
RACK1 receptor for activated C kinase 1 0.0468954
TFG TRK-fused gene 0.0454523
NUP58 nucleoporin 58 0.0454227
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0448796
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0447049
UBA6 ubiquitin-like modifier activating enzyme 6 0.0435511
FAM162A family with sequence similarity 162, member A 0.0418141
TRIO trio Rho guanine nucleotide exchange factor 0.0417436
ACTN1 actinin, alpha 1 0.0412893
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.0410923
HELZ helicase with zinc finger 0.0405902
MKI67 marker of proliferation Ki-67 0.0393189
ENO1 enolase 1, (alpha) 0.0392902
PDIA6 protein disulfide isomerase family A, member 6 0.0392006
PKM pyruvate kinase, muscle 0.0391629
TGM2 transglutaminase 2 0.0387802
HOOK2 hook microtubule-tethering protein 2 0.0386663
LMNA lamin A/C 0.0385471
HILPDA hypoxia inducible lipid droplet-associated 0.0373074
OGA O-GlcNAcase 0.0373059
RPS3 ribosomal protein S3 0.0372589
KIRREL1 kirre like nephrin family adhesion molecule 1 0.0369275
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0368191
ACTN4 actinin, alpha 4 0.0366244
AHNAK2 AHNAK nucleoprotein 2 0.0366193
EZR ezrin 0.0361897
MED15 mediator complex subunit 15 0.0358731
AKAP12 A kinase (PRKA) anchor protein 12 0.0357819
COPA coatomer protein complex, subunit alpha 0.0357434
B2M beta-2-microglobulin 0.0357192
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.0357026
FTL ferritin, light polypeptide 0.0356094
RAB1A RAB1A, member RAS oncogene family 0.0345281
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 0.0335212
ZNF292 zinc finger protein 292 0.0331803
PDPK1 3-phosphoinositide dependent protein kinase 1 0.0328686
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0327135
PPDPF pancreatic progenitor cell differentiation and proliferation factor 0.032311
WAC WW domain containing adaptor with coiled-coil 0.0323044
GARS1 glycyl-tRNA synthetase 1 0.0320409
APLP2 amyloid beta (A4) precursor-like protein 2 0.0319059

decreased expression

Symbol Name Standardized Value
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0967269
EFNA5 ephrin-A5 -0.0741227
ALCAM activated leukocyte cell adhesion molecule -0.0726585
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0546731
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0527036
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0524314
APOL1 apolipoprotein L, 1 -0.0486473
MMP7 matrix metallopeptidase 7 -0.047362
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0473199
RPS2 ribosomal protein S2 -0.0471522
ARHGAP5 Rho GTPase activating protein 5 -0.0467603
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0466227
FAM3C family with sequence similarity 3, member C -0.0450797
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0424408
GOLGB1 golgin B1 -0.0424169
ZBTB20 zinc finger and BTB domain containing 20 -0.0421735
CDCP1 CUB domain containing protein 1 -0.0419135
MYO1E myosin IE -0.0401261
DSG2 desmoglein 2 -0.039912
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.0360065
NRG3 neuregulin 3 -0.0353954
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0350912
MAML2 mastermind-like 2 (Drosophila) -0.0343353
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0342761
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -0.0326054
MACC1 metastasis associated in colon cancer 1 -0.0321293
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0314156
SAMD4A sterile alpha motif domain containing 4A -0.0313451
OSMR oncostatin M receptor -0.0311932
DSCAM Down syndrome cell adhesion molecule -0.0301491
GCC2 GRIP and coiled-coil domain containing 2 -0.029966
NABP1 nucleic acid binding protein 1 -0.0299219
PHF3 PHD finger protein 3 -0.029655
BICC1 BicC family RNA binding protein 1 -0.0296413
BPTF bromodomain PHD finger transcription factor -0.0291179
DOCK5 dedicator of cytokinesis 5 -0.0291085
JMJD1C jumonji domain containing 1C -0.028783
TMC5 transmembrane channel-like 5 -0.0285865
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.028527
IFI16 interferon, gamma-inducible protein 16 -0.028236
DPYD dihydropyrimidine dehydrogenase -0.0275877
SP100 SP100 nuclear antigen -0.0275102
IFI27 interferon, alpha-inducible protein 27 -0.0272379
NUMB numb homolog (Drosophila) -0.0270901
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0269398
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.0268763
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0267325
NRIP1 nuclear receptor interacting protein 1 -0.0266962
TMEM165 transmembrane protein 165 -0.0263344
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.0260648
DST dystonin -0.0259123
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0253948
ASPH aspartate beta-hydroxylase -0.0251869
CP ceruloplasmin (ferroxidase) -0.0251475
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0250975
TPT1 tumor protein, translationally-controlled 1 -0.0249339
RAB10 RAB10, member RAS oncogene family -0.0248842
CD2AP CD2-associated protein -0.0248602
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0247057
SYNRG synergin, gamma -0.0246951
SAMD9 sterile alpha motif domain containing 9 -0.0243005
PDE4D phosphodiesterase 4D, cAMP-specific -0.024292
LMO7 LIM domain 7 -0.0242196
NRP1 neuropilin 1 -0.0241151
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0235936
ARB2A ARB2 cotranscriptional regulator A -0.0235558
EXT1 exostosin glycosyltransferase 1 -0.0235193
PMP22 peripheral myelin protein 22 -0.023497
TJP1 tight junction protein 1 -0.0234018
MBD5 methyl-CpG binding domain protein 5 -0.0231049
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0229841
USP34 ubiquitin specific peptidase 34 -0.0228507
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like -0.0227901
MX2 MX dynamin-like GTPase 2 -0.0219842
MYO9A myosin IXA -0.0219527
SMYD3 SET and MYND domain containing 3 -0.0217568
AHNAK AHNAK nucleoprotein -0.0215135
VMP1 vacuole membrane protein 1 -0.0214464
TFPI2 tissue factor pathway inhibitor 2 -0.0212683
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.02117
RAD51B RAD51 paralog B -0.0209872
RIGI RNA sensor RIG-I -0.020833
ZC3H12C zinc finger CCCH-type containing 12C -0.0207396
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0207059
BOD1L1 biorientation of chromosomes in cell division 1-like 1 -0.0206747
XRN1 5'-3' exoribonuclease 1 -0.0206441
PTPN14 protein tyrosine phosphatase, non-receptor type 14 -0.0205316
USP53 ubiquitin specific peptidase 53 -0.0202644
MX1 MX dynamin-like GTPase 1 -0.0202448
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 -0.019933
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0196832
WWTR1 WW domain containing transcription regulator 1 -0.0196712
FAF1 Fas (TNFRSF6) associated factor 1 -0.0196496
FBXL20 F-box and leucine-rich repeat protein 20 -0.0194298
ATXN1 ataxin 1 -0.0194118
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.0194
CLTC clathrin, heavy chain (Hc) -0.0193723
FAAH2 fatty acid amide hydrolase 2 -0.0190081
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 -0.018852
ERBIN erbb2 interacting protein -0.0187463