Ferulic acid_CHP-212 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ferulic acid perturbation in CHP-212 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Ferulic acid_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
LPIN1 lipin 1 0.0770033
HELZ helicase with zinc finger 0.0713443
FAM13A family with sequence similarity 13, member A 0.0708231
TRIO trio Rho guanine nucleotide exchange factor 0.0622584
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0592313
ZMIZ1 zinc finger, MIZ-type containing 1 0.0585077
FNDC3B fibronectin type III domain containing 3B 0.0582536
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0523111
DST dystonin 0.0511709
MYH9 myosin, heavy chain 9, non-muscle 0.0500898
DSCAM Down syndrome cell adhesion molecule 0.048931
KDM3A lysine (K)-specific demethylase 3A 0.0455267
SEPTIN9 septin 9 0.0449967
EEF2 eukaryotic translation elongation factor 2 0.0443568
ITPRID2 ITPR interacting domain containing 2 0.042002
VEGFA vascular endothelial growth factor A 0.0406729
CDH10 cadherin 10, type 2 (T2-cadherin) 0.040029
ACSL3 acyl-CoA synthetase long-chain family member 3 0.0399126
NAMPT nicotinamide phosphoribosyltransferase 0.0398931
WAC WW domain containing adaptor with coiled-coil 0.0395148
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0382356
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.0376189
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0357051
SMAD3 SMAD family member 3 0.0354528
ZFAND3 zinc finger, AN1-type domain 3 0.0338889
MEF2A myocyte enhancer factor 2A 0.0329961
CASC3 cancer susceptibility candidate 3 0.0327946
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.0327653
YEATS2 YEATS domain containing 2 0.0323626
ADGRG6 adhesion G protein-coupled receptor G6 0.0313587
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0309283
ADARB1 adenosine deaminase, RNA-specific, B1 0.0308547
SOS1 son of sevenless homolog 1 (Drosophila) 0.0300644
SSBP3 single stranded DNA binding protein 3 0.0298854
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0296866
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.029443
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0291877
PTEN phosphatase and tensin homolog 0.0289554
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0289005
NCOR2 nuclear receptor corepressor 2 0.0286373
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0281437
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.0279817
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 0.027868
APP amyloid beta (A4) precursor protein 0.027692
MEIS2 Meis homeobox 2 0.0272841
KMT2C lysine (K)-specific methyltransferase 2C 0.0272181
PTK2 protein tyrosine kinase 2 0.0270406
CNOT1 CCR4-NOT transcription complex, subunit 1 0.0267821
LIMCH1 LIM and calponin homology domains 1 0.0266298
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0265063
EIF4B eukaryotic translation initiation factor 4B 0.0261673
HSPA8 heat shock 70kDa protein 8 0.0261017
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.0254106
ANTXR1 anthrax toxin receptor 1 0.0253065
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.0248665
PLEC plectin 0.0247139
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0246446
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0245642
WDR43 WD repeat domain 43 0.0244537
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0242859
KIRREL1 kirre like nephrin family adhesion molecule 1 0.0242465
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.0239268
ZNF292 zinc finger protein 292 0.0237339
NCKAP1 NCK-associated protein 1 0.0233766
NONO non-POU domain containing, octamer-binding 0.0233297
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.0232493
SRSF1 serine/arginine-rich splicing factor 1 0.0232433
FMN1 formin 1 0.0231955
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0229697
XPO1 exportin 1 0.0229314
MSI2 musashi RNA-binding protein 2 0.0227464
KCTD3 potassium channel tetramerization domain containing 3 0.0226854
CLTC clathrin, heavy chain (Hc) 0.0225908
EWSR1 EWS RNA-binding protein 1 0.022107
RPTOR regulatory associated protein of MTOR, complex 1 0.0217283
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0216612
BIRC6 baculoviral IAP repeat containing 6 0.0215742
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.021559
USP36 ubiquitin specific peptidase 36 0.0210852
NDRG1 N-myc downstream regulated 1 0.0210217
SETD2 SET domain containing 2 0.0208617
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.0208057
AUH AU RNA binding protein/enoyl-CoA hydratase 0.0207897
IGF1R insulin-like growth factor 1 receptor 0.0207034
SMYD3 SET and MYND domain containing 3 0.0206394
COL18A1 collagen, type XVIII, alpha 1 0.0205212
TLE4 transducin-like enhancer of split 4 0.0204611
SREBF2 sterol regulatory element binding transcription factor 2 0.0204585
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.0204154
PELI1 pellino E3 ubiquitin protein ligase 1 0.0203277
CEMIP cell migration inducing protein, hyaluronan binding 0.020289
SSBP2 single-stranded DNA binding protein 2 0.0201616
SPAG9 sperm associated antigen 9 0.0201393
NBAS neuroblastoma amplified sequence 0.0200641
KAT6A K(lysine) acetyltransferase 6A 0.0199907
RUNX1 runt-related transcription factor 1 0.0198965
DDR2 discoidin domain receptor tyrosine kinase 2 0.0198525
BHLHE40 basic helix-loop-helix family, member e40 0.0198446
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 0.0197822
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0197733

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.196532
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -0.128229
IGF2 insulin-like growth factor 2 -0.123347
VIM vimentin -0.121407
PTMA prothymosin, alpha -0.103353
RPS6 ribosomal protein S6 -0.0961832
RPLP1 ribosomal protein, large, P1 -0.0586736
RPL35A ribosomal protein L35a -0.0585147
RPL23 ribosomal protein L23 -0.0538013
RPS24 ribosomal protein S24 -0.0483612
LSAMP limbic system-associated membrane protein -0.0471406
TPT1 tumor protein, translationally-controlled 1 -0.0466346
TMSB10 thymosin beta 10 -0.045181
RPL19 ribosomal protein L19 -0.044396
RPL34 ribosomal protein L34 -0.0441447
NALF1 NALCN channel auxiliary factor 1 -0.0427048
PTPRD protein tyrosine phosphatase, receptor type, D -0.0419828
FTL ferritin, light polypeptide -0.0417187
AKAP12 A kinase (PRKA) anchor protein 12 -0.0416302
RPL26 ribosomal protein L26 -0.0389524
RPS19 ribosomal protein S19 -0.0371502
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.036621
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0362303
RPL31 ribosomal protein L31 -0.0361035
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0351594
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -0.0349347
GNAS GNAS complex locus -0.0347695
RPS3 ribosomal protein S3 -0.0338746
EIF1 eukaryotic translation initiation factor 1 -0.0335555
IFI16 interferon, gamma-inducible protein 16 -0.0330528
RPL12 ribosomal protein L12 -0.0319335
RPS12 ribosomal protein S12 -0.031909
SYT1 synaptotagmin I -0.0313608
BICD1 bicaudal D homolog 1 (Drosophila) -0.0294394
RPS8 ribosomal protein S8 -0.0288095
VCL vinculin -0.028532
RPL32 ribosomal protein L32 -0.0280984
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0280866
CRH corticotropin releasing hormone -0.0276269
RPS14 ribosomal protein S14 -0.0272288
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0272087
ACTG1 actin gamma 1 -0.0271385
S100A9 S100 calcium binding protein A9 -0.0270711
RPS16 ribosomal protein S16 -0.0266941
B2M beta-2-microglobulin -0.0265603
IER3 immediate early response 3 -0.0265174
HILPDA hypoxia inducible lipid droplet-associated -0.0264921
RPL36 ribosomal protein L36 -0.0262888
RHOBTB3 Rho-related BTB domain containing 3 -0.0258109
RPS25 ribosomal protein S25 -0.0257722
ZNF804A zinc finger protein 804A -0.0256655
RPS23 ribosomal protein S23 -0.0253525
SLITRK6 SLIT and NTRK-like family, member 6 -0.0248179
KTN1 kinectin 1 (kinesin receptor) -0.0240852
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0237358
COL1A1 collagen, type I, alpha 1 -0.0233308
RPS5 ribosomal protein S5 -0.0232046
RPLP0 ribosomal protein, large, P0 -0.0230452
RPL7A ribosomal protein L7a -0.0229109
SOX4 SRY (sex determining region Y)-box 4 -0.0228308
KPNB1 karyopherin (importin) beta 1 -0.0227392
TPM4 tropomyosin 4 -0.0221368
RPL28 ribosomal protein L28 -0.0217559
RPL9 ribosomal protein L9 -0.0215261
RPS11 ribosomal protein S11 -0.0213672
RPS29 ribosomal protein S29 -0.0213533
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0212336
DSTN destrin (actin depolymerizing factor) -0.021168
RPS27 ribosomal protein S27 -0.0211444
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0207105
RPL37 ribosomal protein L37 -0.0204853
RSL1D1 ribosomal L1 domain containing 1 -0.0202925
DCAF7 DDB1 and CUL4 associated factor 7 -0.0201589
DLC1 DLC1 Rho GTPase activating protein -0.0201137
LOC102724023 ES1 protein homolog, mitochondrial -0.0196778
IGFBP3 insulin-like growth factor binding protein 3 -0.0193601
PFN1 profilin 1 -0.0193059
LDHB lactate dehydrogenase B -0.0192609
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0190997
SP100 SP100 nuclear antigen -0.0189168
CCND1 cyclin D1 -0.0189004
VDAC1 voltage-dependent anion channel 1 -0.0188904
GREM2 gremlin 2, DAN family BMP antagonist -0.0187402
SERF2 small EDRK-rich factor 2 -0.0186726
RPL11 ribosomal protein L11 -0.0184167
BCAS3 breast carcinoma amplified sequence 3 -0.018315
BPTF bromodomain PHD finger transcription factor -0.0183021
ASTN2 astrotactin 2 -0.0182583
S100A6 S100 calcium binding protein A6 -0.0180607
SLC38A2 solute carrier family 38, member 2 -0.0180471
RPS17 ribosomal protein S17 -0.0179706
LMAN1 lectin, mannose-binding, 1 -0.0179243
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.017862
RPL27 ribosomal protein L27 -0.0177429
NCAM2 neural cell adhesion molecule 2 -0.017705
ASPH aspartate beta-hydroxylase -0.0176751
COL3A1 collagen, type III, alpha 1 -0.0176624
RPLP2 ribosomal protein, large, P2 -0.0174308
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0172443
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0171916